Interaction Details

There were no interactions found between Entrectinib and Autumn Crocus. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Entrectinib and Autumn Crocus? Ask Dr. Brian Staiger about it by contacting him directly.

Autumn Crocus Overview

Autumn Crocus Autumn crocus, a perennial herb native to Europe and North Africa, grows from an underground corm and has been known for over 2000 years as a poisonous plant. It contains colchicine and resembles onion, wild garlic, and wild leek, leading to accidental ingestion and colchicine poisoning. Historically, extracts have been used to treat gout and rheumatoid arthritis. However, it is considered unsafe for oral consumption due to its toxicity, causing adverse effects such as agranulocytosis, aplastic anemia, and peripheral neuritis. Topical exposure can cause finger numbness. Due to these risks, it is recommended to use the standardized, FDA-approved prescription form of colchicine for treating conditions like gout and familial Mediterranean fever, under the supervision of a medical professional.
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Entrectinib Overview

  • Entrectinib is used to treat a certain type of non-small cell lung cancer (NSCLC) in adults that has spread to other parts of the body. It is also used to treat certain types of solid tumors in adults and children 12 years of age and older that cannot be treated by surgery or that has spread to other parts of the body and that worsened after treatment with other chemotherapy medications. Entrectinib is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

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Autumn Crocus - More Interactions

Autumn Crocus interacts with 2 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Ask A Pharmacist About Your Herbal Questions!

Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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