Dyer's Broom - Acetaminophen, Caffeine, Codeine, Salicylamide Interaction
Herbal: Dyer's Broom
Also Known As: Genista tinctoria, Broom Flower, Dyers Broom, Dyer's Greenwood, Dyer's Weed, Dyer's Whin, Fleur à Teindre, Furze, Genestrelle, Genêt Bâtard, Genêt des Teinturiers, Genette, Green Broom, Greenweed, Herbe à Jaunir, Herbe à Teindre, Petit Gênet, Spargelle, Wood Waxen
Drug: Acetaminophen, Caffeine, Codeine, Salicylamide
Brand names:
Codalan No.1, Codalan No.2, Codalan No.3
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jul 22, 2023
Interaction Details
Acetaminophen, Caffeine, Codeine, Salicylamide is classified as belonging to the following category: Caffeine
Theoretically, dyer's broom might reduce the clearance of caffeine.
Dyer's broom contains genistein. Taking genistein 1 gram daily for 14 days seems to inhibit caffeine clearance and metabolism in healthy females. This effect has been attributed to inhibition of the cytochrome P450 1A2 (CYP1A2) enzyme, which is involved in caffeine metabolism. It is unclear if this effect occurs with the lower amounts of genistein found in dyer's broom.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Chen, Y., Xiao, C. Q., He, Y. J., Chen, B. L., Wang, G., Zhou, G., Zhang, W., Tan, Z. R., Cao, S., Wang, L. P., and Zhou, H. H. Genistein alters caffeine exposure in healthy female volunteers. Eur.J Clin.Pharmacol. 2011;67(4):347-353.
Dyer's Broom Overview
Dyer's broom (Genista tinctoria) is a flowering plant that is native to Europe and North Africa. The plant's roots and stems contain a yellow dye called "weld" and has been traditionally used as a natural dye for textiles and other materials. In traditional medicine, Dyers' broom has been used for a variety of purposes, including treating skin irritation, respiratory problems, gout, lower back and pelvic pain, and digestive issues.
Dyer's Broom - More Interactions
Dyer's Broom interacts with 29 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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