Interaction Details

There were no interactions found between Alvimopan and Gamma Butyrolactone (gbl). This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Alvimopan and Gamma Butyrolactone (gbl)? Ask Dr. Brian Staiger about it by contacting him directly.

Gamma Butyrolactone (gbl) Overview

Gamma Butyrolactone (gbl) Gamma butyrolactone (GBL) is a chemical compound found in a wide range of industrial products, including cleaning solutions and nail varnish. Its main use is as a solvent and reagent. If consumed, GBL is metabolized to gamma-hydroxybutyrate (GHB), a potent sedative that can produce relaxation, euphoria and hallucinations. GHB is commonly known as the 'date-rape drug'. The use of GBL for medicinal purposes is not recommended. GBL is federally classified as a Schedule I controlled substance in the United States, making its production, sale, and possession illegal.
See More Information Regarding Gamma Butyrolactone (gbl)

Alvimopan Overview

  • Alvimopan is used to help the bowel recover more quickly after bowel surgery, so that you can eat solid foods and have regular bowel movements. Alvimopan is in a class of medications called peripherally acting mu-opioid receptor antagonists. It works by protecting the bowel from the constipation effects of opioid (narcotic) medications that are used to treat pain after surgery.

See More Information Regarding Alvimopan

Gamma Butyrolactone (gbl) - More Interactions

Gamma Butyrolactone (gbl) interacts with 268 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

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Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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