Interaction Details

There were no interactions found between Vestronidase Alfa-Vjbk and Wild Lettuce. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Vestronidase Alfa-Vjbk and Wild Lettuce? Ask Dr. Brian Staiger about it by contacting him directly.

Pharmacist Analysis

Studies are few and far between, but the only reported interactions with wild lettuce are with sedative drugs as wild lettuce is purported to have sedative effects.

This would include drugs like antihistamines, opioids, and benzodiazepines. These are detailed on our individual drug interaction pages.

Additionally, as wild lettuce may contain hyoscyamine, an anticholinergic drug, it should be used cautiously with other anticholinergic drugs due to the increased risk of side effects.


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Wild Lettuce Overview

Wild Lettuce Wild lettuce (Lactuca virosa) is a plant species in the lettuce family that is native to Europe and parts of Asia. It is a tall, annual plant with small, yellow flowers and leaves that resemble the leaves of cultivated lettuce. Wild lettuce is sometimes called "opium lettuce" due to the milky sap it contains that has been purported to have sedative and analgesic effects. Wild lettuce has a long history of use in traditional medicine. It is thought to have various medicinal properties, including sedative, analgesic, and antispasmodic effects. It is used to treat a variety of conditions, including insomnia, anxiety, and pain.
See More Information Regarding Wild Lettuce

Wild Lettuce - More Interactions

Wild Lettuce interacts with 390 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

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Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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