Interaction Details

There were no interactions found between Levoleucovorin and Alpha Hydroxy Acids (ahas). This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Levoleucovorin and Alpha Hydroxy Acids (ahas)? Ask Dr. Brian Staiger about it by contacting him directly.

Alpha Hydroxy Acids (ahas) Overview

Alpha Hydroxy Acids (AHAs) are natural acids found in foods like citrus fruits, sugarcane, sour milk, apples, and grapes. They are used in cosmetics and diet supplements, with some taken orally, intravaginally, or by inhalation. In dermatology, AHAs may help combat hyperkeratinization, any have been used to treat acne, dry skin, and photo-aging by exfoliating dead skin cells. Smaller AHAs like glycolic acid penetrate the skin more deeply. They reduce the stratum corneum's thickness, improving flexibility, possibly by interfering with enzymes. Studies show AHAs, especially in combination with intense pulsed light therapy, effectively treat acne. Some AHAs like tartaric acid are more relevant for gastrointestinal and respiratory health, while others like malic acid are used for saliva production and blood pressure control. It's important to consider each AHA individually for its specific effects.
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Levoleucovorin Overview

  • Levoleucovorin injection is used in adults and children to prevent harmful effects of methotrexate (Trexall) when methotrexate is used to treat osteosarcoma (cancer that forms in bones). Levoleucovorin injection is also used to treat adults and children who have accidentally received an overdose of methotrexate or similar medications or who are not able to eliminate these medications properly from their bodies. Levoleucovorin injection is also used with fluorouracil (5-FU, a chemotherapy medication) to treat adults with colorectal cancer (cancer that begins in the large intestine) that has spread to other parts of the body. Levoleucovorin injection is in a class of medications called folic acid analogs. It works to prevent the harmful effects of methotrexate by protecting healthy cells, while allowing methotrexate to enter and kill cancer cells. It works to treat colorectal cancer by increasing the effects of fluorouracil.

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Alpha Hydroxy Acids (ahas) - More Interactions

Alpha Hydroxy Acids (ahas) interacts with 0 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

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Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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