Amaranth - Reclast (Zoledronic Acid) Interaction
Herbal: Amaranth
Also Known As: Amaranthus blitum, Amaranthus caudatus, Amaranthus cruentus, Amaranto, Chua, Huantli, Huatlí, Kantanoty, Lady Bleeding, Love-Lies-Bleeding, Lovely Bleeding, Pilewort, Prickly Amaranth, Prince's Feather, Rajgira, Ramdana, Red Cockscomb, Red Spinach, Rhamdana, Royal Grain, Smo
Drug: Zoledronic Acid
Brand names:
Zometa, Aclasta, Reclast
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Apr 13, 2024
Interaction Details
There were no interactions found between Zoledronic Acid and Amaranth. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Amaranth Overview
Amaranth is a diverse group of plants found in lowlands, wastelands, and gardens, with some species yielding seeds used as pseudocereals or for oil. Others, like Amaranthus dubius and Amaranthus tricolor, have large leaves used as vegetables. Common medicinal varieties include Amaranthus roxburghianus and Amaranthus spinosus.
The whole amaranth plant is used medicinally. Its leaves contain some vitamin C and beta-carotene, with Amaranthus tricolor leaves also providing calcium, iron, and zinc. Amaranth seed oil is rich in unsaturated fatty acids (UFAs), including linoleic, alpha-linolenic, and oleic acids, along with saturated fatty acids (SFAs) like palmitic and stearic acids, in a 1:3 SFA to UFA ratio, and also contains squalene, tocopherols, and sterols.
Amaranth seeds, used as pseudocereals, are high in protein, vitamin E, antioxidant phenols, and minerals like iron. Amaranthus hypochondriacus seeds contain bioactive peptides like lunasin, vicilin, and 11S globulin. Amaranthus roxburghianus roots contain eugenol, benzene derivatives, and 3,5-dihydroxy-6-methyl-2,3-dihydropyran-4-one, while Amaranthus spinosus bark contains betacyanins, quercetin, kaempferol, and amaranthoside.
Zoledronic Acid Overview
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Zoledronic acid (Reclast) is used to prevent or treat osteoporosis (condition in which the bones become thin and weak and break easily) in women who have undergone menopause ('change of life,' end of regular menstrual periods). Zoledronic acid (Reclast) is also used to treat osteoporosis in men, and to prevent or treat osteoporosis in men and women who are taking glucocorticoids (a type of corticosteroid medication that may cause osteoporosis). Zoledronic acid (Reclast) is also used to treat Paget's disease of bone (a condition in which the bones are soft and weak and may be deformed, painful, or easily broken). Zoledronic acid (Zometa) is used to treat high levels of calcium in the blood that may be caused by certain types of cancer. Zoledronic acid (Zometa) is also used along with cancer chemotherapy to treat bone damage caused by multiple myeloma [cancer that begins in the plasma cells (white blood cells that produce substances needed to fight infection)] or by cancer that began in another part of the body but has spread to the bones. Zoledronic acid (Zometa) is not cancer chemotherapy, and it will not slow or stop the spread of cancer. However, it can be used to treat bone disease in patients who have cancer. Zoledronic acid is in a class of medications called bisphosphonates. It works by slowing bone breakdown, increasing bone density (thickness), and decreasing the amount of calcium released from the bones into the blood.
Amaranth - More Interactions
Amaranth interacts with 0 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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