Arabinoxylan - Cimzia (Certolizumab) Interaction
Herbal: Arabinoxylan
Also Known As: Arabinoxilano, Arabinoxylane, Pentosan
Drug: Certolizumab
Brand names:
Cimzia
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 09, 2024
Interaction Details
There were no interactions found between Certolizumab and Arabinoxylan. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Arabinoxylan Overview
Arabinoxylan is a type of dietary fiber present in the cell walls of cereal grains such as wheat, corn, rice, rye, oat, and barley. It has a structure comprising a xylose backbone with arabinose side chains and can be extracted from byproducts of wheat-flour processing. In natural medicine, arabinoxylan has been utilized to address conditions like diabetes, impaired glucose tolerance, and metabolic syndrome. However, the evidence supporting its effectiveness in these areas is currently insufficient.
Mechanistically, arabinoxylan functions as a prebiotic, fostering the growth of bifidobacteria in the gut. It may also reduce colonic protein fermentation while boosting the production of short-chain fatty acids. Arabinoxylan in clinical research has demonstrated hypoglycemic effects by lowering postprandial glucose levels and hypolipidemic effects by reducing serum triglycerides.
Certolizumab Overview
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Certolizumab injection is used to relieve the symptoms of certain autoimmune disorders (conditions in which the immune system attacks healthy parts of the body and causes pain, swelling, and damage) including the following:
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Crohn's disease (a condition in which the body attacks the lining of the digestive tract, causing pain, diarrhea, weight loss, and fever) that has not improved when treated with other medications,
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rheumatoid arthritis (a condition in which the body attacks its own joints, causing pain, swelling, and loss of function),
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psoriatic arthritis (a condition that causes joint pain and swelling and scales on the skin),
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active ankylosing spondylitis (a condition in which the body attacks the joints of the spine and other areas causing pain, swelling, and joint damage) with changes seen on X-ray,
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active non-radiographic axial spondyloarthritis (a condition in which the body attacks the joints of the spine and other areas causing pain and signs of swelling), but without changes seen on X-ray,
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plaque psoriasis (a skin disease in which red, scaly patches form on some areas of the body) in people who may benefit from medications or phototherapy (a treatment that involves exposing the skin to ultraviolet light).
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Certolizumab injection is in a class of medications called tumor necrosis factor (TNF) inhibitors. It works by blocking the activity of TNF, a substance in the body that causes inflammation.
Arabinoxylan - More Interactions
Arabinoxylan interacts with 84 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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