Ashwagandha - Amoxicillin Interaction
Herbal: Ashwagandha
Also Known As: Withania somnifera, Ajagandha, Amangura, Asan, Asana, Asgand, Asgandh, Asgandha, Ashagandha, Ashvagandha, Ashwaganda, Ashwanga, Asoda, Asundha, Aswagandha, Avarada, Ayurvedic Ginseng, Cerise d'Hiver, Clustered Wintercherry, Ghoda Asoda
Drug: Amoxicillin
Brand names:
Amoxil Capsules, Trimox, Wymox, Amix, Amoram, Amoxident, Galenamox, Rimoxallin, Amoxil Injection
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 02, 2024
Interaction Details
There were no interactions found between Amoxicillin and Ashwagandha. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Pharmacist Analysis
The use of ashwagandha may result in potential interactions with certain classes of medication due to its known effects. However, these interactions are generally considered to be of minimal clinical significance.
Nevertheless, it is recommended to exercise caution when using ashwagandha in conjunction with the following classes of drugs:
- Antidiabetes
- Antihypertensives
- Benzodiazepines
- CNS Depressants
- Immunosuppressant
- Thyroid Hormones
Although ashwagandha can typically be used safely in combination with these drug classes, it is crucial to inform your healthcare provider of all medications and supplements you are taking to ensure proper monitoring. Based on available information, ashwagandha does not appear to cause any adverse interactions with the specific drug mentioned in this inquiry.
Ashwagandha With Amoxicillin - Additional Details
There is currently no known interaction between ashwagandha and amoxicillin, as noted above.
This is likely because both work on different pathways in the body and the fact that ashwagandha doesn't appear to affect amoxicillin metabolism.
Additionally, although ashwagandha doesn't seem to affect CYP liver metabolizing enzymes to a significant degree, amoxicillin is excreted in the urine via tubular secretion and glomerular filtration. It is not affected by CYP enzymes.
Overall, no clinically significant interaction is expected between amoxicillin and ashwagandha. They are generally considered safe to take together.
- Dr. Brian Staiger, PharmDAshwagandha Overview
Amoxicillin Overview
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Amoxicillin is used to treat certain infections caused by bacteria, such as pneumonia; bronchitis (infection of the airway tubes leading to the lungs); and infections of the ears, nose, throat, urinary tract, and skin. It is also used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers. Amoxicillin is in a class of medications called penicillin-like antibiotics. It works by stopping the growth of bacteria.
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Antibiotics such as amoxicillin will not work for colds, flu, and other viral infections. Taking antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
Ashwagandha - More Interactions
Ashwagandha interacts with 625 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.