Bear's Garlic - Triumeq (Abacavir Sulfate, Dolutegravir, Lamivudine) Interaction
Herbal: Bear's Garlic
Also Known As: Allium ursinum, Ail des Bois, Ail à Feuilles Larges, Ail des Ours, Ail Pétiolé, Ajo de Oso, Ajo Silvestre, Baerlauch, Bear Garlic, Broad-leaved Garlic, Hog's Garlic, Ramsons, Wild Garlic, Wood Garlic
Drug: Abacavir Sulfate, Dolutegravir, Lamivudine
Brand names:
Triumeq
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Apr 13, 2024
Interaction Details
There were no interactions found between Abacavir Sulfate, Dolutegravir, Lamivudine and Bear's Garlic. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Bear's Garlic Overview
Bear's garlic, also known as wild garlic or Allium ursinum, is a perennial plant native to Europe and parts of Asia. The herb and bulb of bear's garlic are commonly used in culinary applications, prized for their mild garlic flavor. Bear's garlic contains various beneficial compounds, including glucopyranoside, kaempferol, and flavonoids, although levels of alliin, a compound found in garlic, are lower in bear's garlic. It's important to note that many of these compounds are degraded if the plant is dried.
Research suggests that bear's garlic exhibits cardioprotective effects, with in vitro studies showing promising results. It moderately inhibits the angiotensin-converting enzyme (ACE), which could contribute to its purported cardioprotective and blood pressure-lowering effects. Additionally, bear's garlic leaf extract has been found to inhibit platelet aggregation in vitro, mainly through the inhibition of the ADP pathway. Specific non-sulphur constituents, such as 1,2-di-O-alpha-linolenoyl-3-O-beta-D-galactopyranosyl-sn-glycerol and beta-sitosterol-3-O-beta-D-glucoside, appear to be the most active antiplatelet constituents, along with some flavonoids.
Abacavir Sulfate, Dolutegravir, Lamivudine Overview
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The combination of abacavir, dolutegravir, and lamivudine is used alone or along with other medications to treat HIV infection in certain adults and children who weigh at least 88 lb (40 kg). Abacavir and lamivudine are in a class of medications called nucleoside analogue reverse transcriptase inhibitors (NRTIs) and dolutegravir is in a class of medications called integrase strand transfer inhibitors (INSTIs). They work by decreasing the amount of HIV in your blood and increasing the number of immune cells that help fight infections in your body. Although abacavir, dolutegravir, and lamivudine will not cure HIV, these medications may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer. Taking these medications along with practicing safer sex and making other lifestyle changes may decrease the risk of getting or transmitting the HIV virus to other people.
Bear's Garlic - More Interactions
Bear's Garlic interacts with 118 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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