Interaction Details

Promazine is classified as belonging to the following category: Antipsychotic Drugs

Cannabis does not seem to affect blood levels or effects of some antipsychotic drugs.
Human research shows that cannabis use does not affect blood levels or clinical effects of amisulpride, aripiprazole, or olanzapine in patients with schizophrenia and related disorders.

Interaction Rating

Minor

Likelihood of Occurrence

Unlikely

Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

References

  • Alisauskiene R, Johnsen E, Gjestad R, et al. Does drug use affect the efficacy of amisulpride, aripiprazole and olanzapine in patients with schizophrenia spectrum disorders? Results from a pragmatic, randomised study. Gen Hosp Psychiatry 2023;83:185-193.

Cannabis Overview

Cannabis Cannabis, also known as marijuana, is a plant that contains more than 100 compounds known as cannabinoids. Some of these compounds can have psychoactive effects when consumed, which is why cannabis is often used for recreational purposes. However, cannabis has also been used for medicinal purposes and specific compounds found in cannabis (e.g., THC, CBD, CBN) are thought to have different effects and work on different receptors in the body. The two main cannabinoids in cannabis that are used medicinally are tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is the psychoactive compound in cannabis, while CBD is not psychoactive. Cannabidiol (CBD) is also found in the prescription drug Epidiolex and is used to treat certain types of seizures.
See More Information Regarding Cannabis

Cannabis - More Interactions

Cannabis interacts with 1095 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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