Interaction Details

There were no interactions found between Peginterferon alfa-2b and Coenzyme Q10. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Peginterferon alfa-2b and Coenzyme Q10? Ask Dr. Brian Staiger about it by contacting him directly.

Pharmacist Analysis

Although CoQ10 is considered relatively safe for most individuals, it does have some reported interactions that are important to be aware of.

This includes:

  • Antihypertensives: Clinical research has shown that CoQ10 can significantly lower blood pressure but conflicting results have been reported.
  • Warfarin: Research is conflicting but concomitant use of CoQ10 and warfarin might reduce the anticoagulant effects of warfarin.
  • Alkylating Agents: Antioxidants such as CoQ10 might also protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy.

Outside of the interactions I've listed above, CoQ10 is generally considered safe to supplement with in most situations.

In fact, some individuals taking certain medications (e.g., 'Statins') may be recommended to take it.

If you have any questions about CoQ10 supplements, be sure to speak to your healthcare professional. We are always happy to answer questions on the matter as well!

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Coenzyme Q10 Overview

Coenzyme Q10, also known as CoQ10, is a naturally occurring substance that is found in every cell of the body and plays an essential role in energy production within the mitochondria, which are the powerhouse of the cells. CoQ10 also acts as an antioxidant, protecting cells from damage caused by harmful free radicals. While CoQ10 is endogenous, meaning our body can produce it on its own, levels can decrease with age, with certain medications (e.g., statins) or due to certain medical conditions. In such cases, supplementation with CoQ10 may be beneficial. Additionally, CoQ10 supplements have been studied for a variety of health benefits, including improving heart health, reducing inflammation, and potentially even aiding in the treatment of neurological disorders such as Parkinson's disease. However, it's important to note that while some studies have shown potential benefits, the research on CoQ10 supplementation is still ongoing, and more studies are needed to fully understand its effects on the body.
See More Information Regarding Coenzyme Q10

Peginterferon alfa-2b Overview

  • Peginterferon alfa-2b is used alone or in combination with ribavirin (a medication) to treat chronic (long-term) hepatitis C infection (swelling of the liver caused by a virus) in people who show signs of liver damage and who have not been treated with interferon alpha (medication similar to peginterferon alfa-2b) in the past. Peginterferon alfa-2b is in a class of medications called interferons. Peginterferon alpha-2b is a combination of interferon and polyethylene glycol, which helps the interferon stay active in your body for a longer period of time. Peginterferon alpha-2b works by decreasing the amount of hepatitis C virus (HCV) in the body. Peginterferon alfa-2b may not cure hepatitis C or prevent you from developing complications of hepatitis C such as cirrhosis (scarring) of the liver, liver failure, or liver cancer. Peginterferon alfa-2b may not prevent the spread of hepatitis C to other people.

See More Information Regarding Peginterferon Alfa-2b (PEG-Intron)

Coenzyme Q10 - More Interactions

Coenzyme Q10 interacts with 194 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Ask A Pharmacist About Your Herbal Questions!

Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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