Cola Nut - Tarka (Trandolapril, Verapamil) Interaction
Herbal: Cola Nut
Also Known As: Cola acuminata, Bissey Nut, Bissy Nut, Bitter Kola, Guru Nut, Gworo, Kola Nut, Kolatier, Noix de Cola, Noix de Kola, Noix du Soudan, Nuez de Cola, Soudan Coffee
Drug: Trandolapril, Verapamil
Brand names:
Tarka
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 26, 2024
Interaction Details
Trandolapril, Verapamil is classified as belonging to the following category: Verapamil (Calan, Others)
Theoretically, concomitant use might increase the levels and adverse effects of both verapamil and caffeine.
Cola nut contains caffeine. Verapamil increases plasma caffeine concentrations by 25%.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Carrillo JA, Benitez J. Clinically significant pharmacokinetic interactions between dietary caffeine and medications. Clin Pharmacokinet 2000;39:127-53.
Cola Nut Overview
Cola Nut - More Interactions
Cola Nut interacts with 646 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
Unknown | No interactions have been reported or no interaction data is currently available. |
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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Drug descriptions are provided by MedlinePlus.