Comfrey - Bufferin (Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide) Interaction
Herbal: Comfrey
Also Known As: Symphytum officinale, Ass Ear, Beinwellwurzel, Black Root, Blackwort, Bruisewort, Common Comfrey, Consolidae Radix, Consoude, Consoude Officinale, Consound, Consuelda, Grande Consoude, Gum Plant, Healing Herb, Herbe aux Charpentiers, Herbe à la Coupure, Knitback
Drug: Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide
Brand names:
Bufferin
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Apr 13, 2024
Interaction Details
There were no interactions found between Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide and Comfrey. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Comfrey Overview
Comfrey (Symphytum officinale) is an herbaceous plant that belongs to the borage family (Boraginaceae). It is native to Europe and Asia and is known for its hairy, green leaves and small, purple, bell-shaped flowers.
Comfrey has a long history of use in traditional medicine and contains a number of active compounds, including allantoin, which is believed to have anti-inflammatory and healing properties. It has been traditionally used to treat a variety of ailments, including wounds, fractures, and skin conditions. In addition, comfrey is believed to have astringent and expectorant effects, and has been used to treat respiratory disorders and coughs. It is important to note that comfrey may cause liver damage if taken in large amounts (orally) or over a long period of time and should be used with caution. The FDA has recommended removal of oral comfrey products from the market due to potential for liver toxicity although it is currently still available. It is most often seen in topical forms (e.g., as an ointment).
Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide Overview
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Prescription aspirin is used to relieve the symptoms of rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), osteoarthritis (arthritis caused by breakdown of the lining of the joints), systemic lupus erythematosus (condition in which the immune system attacks the joints and organs and causes pain and swelling) and certain other rheumatologic conditions (conditions in which the immune system attacks parts of the body). Nonprescription aspirin is used to reduce fever and to relieve mild to moderate pain from headaches, menstrual periods, arthritis, toothaches, and muscle aches. Nonprescription aspirin is also used to prevent heart attacks in people who have had a heart attack in the past or who have angina (chest pain that occurs when the heart does not get enough oxygen). Nonprescription aspirin is also used to reduce the risk of death in people who are experiencing or who have recently experienced a heart attack. Nonprescription aspirin is also used to prevent ischemic strokes (strokes that occur when a blood clot blocks the flow of blood to the brain) or mini-strokes (strokes that occur when the flow of blood to the brain is blocked for a short time) in people who have had this type of stroke or mini-stroke in the past. Aspirin will not prevent hemorrhagic strokes (strokes caused by bleeding in the brain). Aspirin is in a group of medications called salicylates. It works by stopping the production of certain natural substances that cause fever, pain, swelling, and blood clots.
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Aspirin is also available in combination with other medications such as antacids, pain relievers, and cough and cold medications. This monograph only includes information about the use of aspirin alone. If you are taking a combination product, read the information on the package or prescription label or ask your doctor or pharmacist for more information.
Comfrey - More Interactions
Comfrey interacts with 409 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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