Ergot - Actimmune (Interferon Gamma-1b) Interaction
Herbal: Ergot
Also Known As: Claviceps purpurea, Cockspur Rye, Cornezuelo, Ergot de Seigle, Hornseed, Mai Jiao, Mother of Rye, Secale Cornutum, Smut Rye, Spurred Rye
Drug: Interferon Gamma-1b
Brand names:
Actimmune
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 23, 2024
Interaction Details
There were no interactions found between Interferon Gamma-1b and Ergot. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Ergot Overview
Ergot is a fungal plant infection that most commonly grows on rye. Ergot contains ergolines, which are alkaloids that have various pharmacologic and toxic effects. A well-known illness from the Middle Ages, St. Anthony's Fire, was brought on by the widespread consumption of fungus-contaminated rye grain which caused ergot poisoning (ergotism). Ergot has been used medicinally for obstetric and gynecologic conditions, such as abnormally heavy bleeding at menstruation since ergot contains chemicals that can help reduce bleeding by causing a narrowing of the blood vessels. Due to the safety concerns of consuming ergot, its use is not recommended.
Interferon Gamma-1b Overview
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Interferon gamma-1b injection is used to reduce the frequency and severity of serious infections in people with chronic granulomatous disease (an inherited immune system disease). It is also used to slow down worsening of their condition in people with severe, malignant osteopetrosis (an inherited bone disease). Interferon gamma-1b is in a class of medications called immunomodulators. It is not known exactly how interferon gamma-1b works to treat chronic granulomatous disease and osteopetrosis.
Ergot - More Interactions
Ergot interacts with 453 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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