Evening Primrose - Casodex (Bicalutamide) Interaction
Herbal: Evening Primrose
Also Known As: Oenothera biennis, Oenothera muricata, Oenothera rubricaulis, Evening star, Suncups, Sundrop
Drug: Bicalutamide
Brand names:
Casodex
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Apr 13, 2024
Interaction Details
There were no interactions found between Bicalutamide and Evening Primrose. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Evening Primrose Overview
Evening primrose (Oenothera biennis) is a plant native to North and Central America and a member of the Onagraceae family. It is an annual plant that has bright yellow flowers that bloom in the evening (hence the name). The plant produces seeds that are rich in a fatty acid called gamma-linolenic acid (GLA).
Evening primrose oil is a dietary supplement that is derived from the seeds of the evening primrose plant. It is rich in GLA (gamma-linolenic acid), an omega-6 fatty acid, and is sometimes taken to improve the health of the skin, reduce inflammation, and reduce the symptoms of premenstrual syndrome (PMS). It has also been used historically for alcohol use disorder.
Dietary supplements containing evening primrose oil generally are standardized by their gamma-linolenic acid (GLA) and linoleic acid (LA) content.
Bicalutamide Overview
-
Bicalutamide is used with another medication (gonadotropin-releasing hormone (GnRH) agonists; such as leuprolide or goserelin) to treat metastatic prostate cancer (cancer that started in the prostate and has spread to other parts of the body). Bicalutamide is in a class of medications called nonsteroidal antiandrogens. It works by blocking the effect of androgen (a male hormone), to stop the growth and spread of cancer cells.
Evening Primrose - More Interactions
Evening Primrose interacts with 226 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
Return to the main herbal interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
Ask A Pharmacist About Your Herbal Questions!
Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
Ask A Pharmacist