Interaction Details

There were no interactions found between Clindamycin and Fenugreek. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Clindamycin and Fenugreek? Ask Dr. Brian Staiger about it by contacting him directly.

Pharmacist Analysis

Fenugreek is generally considered relatively safe in regard to potential drug interactions.

Nevertheless, interactions are possible between fenugreek and:

  • 'Blood-thinning' drugs
  • Drugs that lower blood pressure
  • Drugs that low blood sugar

Fenugreek contains some components that can prevent blood from clotting. However, there is not enough research to confirm whether the amount of these components present in common fenugreek products can have a clinically significant effect.

Fenugreek may also have an additive effect with blood sugar-lowering medication and blood pressure-lowering medication.

All of these potential interactions are documented individually on our specific drug-herbal interaction pages.

Is Fenugreek Safe With Clindamycin?

Fenugreek is not known to interact with most antibiotic medications, including clindamycin.

While fenugreek may have additive effects with several different classes of drugs (e.g., blood-pressure medications and anticoagulants), it is not known to affect any liver metabolizing enzymes and is not known to affect how any antibiotic works.

In fact, some studies even suggest fenugreek may have mild antimicrobial effects (one study suggests it may help heal ulcers caused by the bacteria H.pylori faster).

Overall, there is no indication fenugreek interacts with clindamycin and they are generally considered safe to take together.

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Fenugreek Overview

Fenugreek Fenugreek (Trigonella foenum-graecum) is a plant native to the Mediterranean region and western Asia. The seeds have a nutty, slightly bitter taste and are commonly used in different types of cuisine. The leaves, which are known as "methi," are used in cooking as well. In addition to its use as a spice and herb, fenugreek has a long history of use in traditional medicine. Some studies have suggested that fenugreek may have potential health benefits, including the ability to lower blood sugar levels in people with diabetes, improve cholesterol levels, and reduce inflammation. It may also have potential benefits for women who are breastfeeding, as it is thought to increase milk production and improve the quality of breast milk.
See More Information Regarding Fenugreek

Clindamycin Overview

  • Clindamycin is used to treat certain types of bacterial infections, including infections of the lungs, skin, blood, female reproductive organs, and internal organs. Clindamycin is in a class of medications called lincomycin antibiotics. It works by slowing or stopping the growth of bacteria.

  • Antibiotics such as clindamycin will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

See More Information Regarding Clindamycin

Fenugreek - More Interactions

Fenugreek interacts with 383 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Ask A Pharmacist About Your Herbal Questions!

Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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