Peppermint - Bufferin (Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide) Interaction
Herbal: Peppermint
Also Known As: Mentha x piperita, Black Peppermint, Brandy Mint, Extract of Peppermint, Field Mint, Herba Menthae, Huile de Menthe Poivrée, Lamb Mint, M. Balsamea Willd Extract, Menta Pepperita, Menta Piperita, Mentha Balsamea, Mentha Oil, Mentha Piperita Extract, Mentha Piperita Oil
Drug: Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide
Brand names:
Bufferin
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 26, 2024
Interaction Details
There were no interactions found between Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide and Peppermint. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Pharmacist Analysis
Peppermint and peppermint oil have a number of theoretical interactions due to several lab and animal studies suggesting it can inhibit a variety of CYP metabolizing enzymes in the liver, including:
- CYP2C9
- CYP3A4
- CYP2C19
- CYP1A2
However, many of these interactions have not been seen in humans, and the likelihood of them being clinically significant is low. They are nevertheless important to be aware of.
There is no known interaction between peppermint and the drug in question here. They are considered safe to combine.
- Dr. Brian Staiger, PharmDPeppermint Overview
Peppermint is a perennial herb that is native to Europe and Asia. It is a member of the mint family (Lamiaceae) and is known for its fragrant, minty aroma and distinctive, spear-shaped leaves.
Peppermint is commonly used in cooking and aromatherapy, as well as in a variety of personal care products. It has a refreshing, cool, and slightly sweet flavor.
In traditional medicine, peppermint is believed to have a number of health benefits. It is thought to have anti-inflammatory and pain-relieving effects, and it is sometimes used to treat a variety of conditions, including digestive problems, respiratory infections, and skin disorders.
Peppermint is also commonly used as a natural treatment for colds and flu due to its expectorant properties.
Some peppermint supplements are marketed specifically towards those suffering from IBS (irritable bowel syndrome) as evidence shows it can help reduce symptoms in some individuals.
Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide Overview
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Prescription aspirin is used to relieve the symptoms of rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), osteoarthritis (arthritis caused by breakdown of the lining of the joints), systemic lupus erythematosus (condition in which the immune system attacks the joints and organs and causes pain and swelling) and certain other rheumatologic conditions (conditions in which the immune system attacks parts of the body). Nonprescription aspirin is used to reduce fever and to relieve mild to moderate pain from headaches, menstrual periods, arthritis, toothaches, and muscle aches. Nonprescription aspirin is also used to prevent heart attacks in people who have had a heart attack in the past or who have angina (chest pain that occurs when the heart does not get enough oxygen). Nonprescription aspirin is also used to reduce the risk of death in people who are experiencing or who have recently experienced a heart attack. Nonprescription aspirin is also used to prevent ischemic strokes (strokes that occur when a blood clot blocks the flow of blood to the brain) or mini-strokes (strokes that occur when the flow of blood to the brain is blocked for a short time) in people who have had this type of stroke or mini-stroke in the past. Aspirin will not prevent hemorrhagic strokes (strokes caused by bleeding in the brain). Aspirin is in a group of medications called salicylates. It works by stopping the production of certain natural substances that cause fever, pain, swelling, and blood clots.
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Aspirin is also available in combination with other medications such as antacids, pain relievers, and cough and cold medications. This monograph only includes information about the use of aspirin alone. If you are taking a combination product, read the information on the package or prescription label or ask your doctor or pharmacist for more information.
Peppermint - More Interactions
Peppermint interacts with 772 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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