Royal Jelly - Coumadin (Warfarin Sodium) Interaction
Herbal: Royal Jelly
Also Known As: Bee Saliva, Bee Spit, Gelée Royale, Honey Bee Milk, Jalea Real, Lait des Abeilles, Royal Bee Jelly
Drug: Warfarin Sodium
Brand names:
Coumadin, Panwarfin, Sofarin
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jul 22, 2023
Interaction Details
Warfarin Sodium is classified as belonging to the following category: Warfarin (Coumadin)
Royal jelly might increase the risk of bleeding when taken with warfarin.
In one case, an 87-year-old male who was previously stabilized on warfarin developed hematuria and was found to have an INR of 7.29 after taking a royal jelly supplement for one week.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Lee NJ, Fermo JD. Warfarin and royal jelly interaction. Pharmacotherapy 2006;26:583-6.
Royal Jelly Overview
Royal jelly is a thick, milky substance produced by worker bees. It is fed to the queen bee during the larval stage of her life, and it is believed to play a key role in her development and fertility.
Royal jelly is rich in nutrients, including proteins, carbohydrates, lipids, vitamins, and minerals. It is also a good source of antioxidants.
Royal jelly is often utilized as used as a dietary supplement as it is purported to have a number of potential health benefits. It is believed to have antioxidant and anti-inflammatory properties, and it is sometimes used to treat a variety of conditions, including skin conditions, asthma, and menopausal symptoms. It is also used to boost the immune system and improve physical and mental performance.
Warfarin Sodium Overview
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Warfarin is used to prevent blood clots from forming or growing larger in your blood and blood vessels. It is prescribed for people with certain types of irregular heartbeat, people with prosthetic (replacement or mechanical) heart valves, and people who have suffered a heart attack. Warfarin is also used to treat or prevent venous thrombosis (swelling and blood clot in a vein) and pulmonary embolism (a blood clot in the lung). Warfarin is in a class of medications called anticoagulants ('blood thinners'). It works by decreasing the clotting ability of the blood.
Royal Jelly - More Interactions
Royal Jelly interacts with 170 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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