Saw Palmetto - Avodart (Dutasteride) Interaction

Interaction Details

Pharmacist Analysis

Both saw palmetto and dutasteride are believed to work by blocking the conversion of testosterone to dihydrotestosterone (DHT), which can contribute to prostate enlargement.

While studies show both can be effective for treating BPH, there is limited research available regarding the potential interaction between saw palmetto and finasteride when used together.

Based on their similar mechanisms of action, it stands to reason that the combined use of saw palmetto and dutasteride may not provide any additional benefit beyond what each medication can provide on its own.

Furthermore, there is a possibility that using both medications together may increase the risk of side effects without much-added benefit.

Therefore, further research is needed to fully understand the potential risks and benefits of combining saw palmetto and dutasteride.

It's unlikely that there is a significant interaction between the two that would result in severe adverse reactions, but as always, it is important to always consult with your doctor before starting or stopping any medication, including natural supplements like saw palmetto.

Both saw palmetto and dutasteride are believed to work by blocking the conversion of testosterone to dihydrotestosterone (DHT), which can contribute to prostate enlargement.

While studies show both can be effective for treating BPH, there is limited research available regarding the potential interaction between saw palmetto and finasteride when used together.

Based on their similar mechanisms of action, it stands to reason that the combined use of saw palmetto and dutasteride may not provide any additional benefit beyond what each medication can provide on its own.

Furthermore, there is a possibility that using both medications together may increase the risk of side effects without much-added benefit.

Therefore, further research is needed to fully understand the potential risks and benefits of combining saw palmetto and dutasteride.

It's unlikely that there is a significant interaction between the two that would result in severe adverse reactions, but as always, it is important to always consult with your doctor before starting or stopping any medication, including natural supplements like saw palmetto.

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On the whole, saw palmetto has very few reported drug interactions due to its lack of effects on liver metabolizing enzymes (e.g., CYP P450 enzymes).

There have been some reports of minor interactions with anticoagulants, estrogens, and contraceptives due to saw palmetto's purported effects on blood clotting and various hormones in the body. However, these interactions have generally only been seen in lab studies and for most individuals, are not considered clinically significant.

As always, however, be sure to talk to your doctor before starting any new medications or supplements so you can be appropriately monitored.

Dutasteride Overview

• Dutasteride is used alone or with another medication (tamsulosin [Flomax]) to treat benign prostatic hyperplasia (BPH; enlargement of the prostate gland). Dutasteride is used to treat symptoms of BPH and may reduce the chance of developing acute urinary retention (sudden inability to urinate). Dutasteride may also decrease the chance that prostate surgery will be needed. Dutasteride is in a class of medications called 5-alpha reductase inhibitors. It works by blocking the production of a natural substance that enlarges the prostate.

Saw Palmetto - More Interactions

Saw Palmetto interacts with 170 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.