Turpentine Oil - Neupro (Rotigotine) Interaction
Herbal: Turpentine Oil
Also Known As: Pinus palustris, Aceite de Trementina, Essence de Térébenthine, Huile de Pin, Huile de Térébenthine, Huile de Térébenthine Purifiée, Pine Oleoresin, Pine Tree Terpenic, Purified Turpentine Oil, Spirits of Turpentine, Térébenthine, Terebinthinae Aetheroleum
Drug: Rotigotine
Brand names:
Neupro
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 02, 2024
Interaction Details
Rotigotine is classified as belonging to the following category: Topical Drugs
Some in vitro research shows that alpha-pinene, the major constituent of turpentine oil, does not increase the absorption of chlorpromazine or haloperidol when applied topically. However, animal research shows that turpentine oil increases the absorption of ibuprofen when applied topically. Theoretically, applying turpentine oil to the skin along with other medications might increase the effects and side effects of these medications.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Jiang Q, Wu Y, Zhang H, et al. Development of essential oils as skin permeation enhancers: penetration enhancement effect and mechanism of action. Pharmaceutical Biol. 2017;55(1):1592-1600.
- Almirall M, Montana J, Excribano E, Obach R, Berrozpe JD. Effect of d-limonene, alpha-pinene, and cineole on in vitro transdermal human skin penetration of chlorpromazine and haloperidol. Arzneimittelforschung. 1996 Jul;46(7):676-80.
Turpentine Oil Overview
Rotigotine Overview
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Rotigotine transdermal patches are used to treat the signs and symptoms of Parkinson's disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) including shaking of parts of the body, stiffness, slowed movements, and problems with balance. Rotigotine transdermal patches are also used to treat restless legs syndrome (RLS or Ekbom syndrome; a condition that causes discomfort in the legs and a strong urge to move the legs, especially at night and when sitting or lying down). Rotigotine is in a class of medications called dopamine agonists. It works by acting in place of dopamine, a natural substance produced in the brain that is needed to control movement.
Turpentine Oil - More Interactions
Turpentine Oil interacts with 361 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
Unknown | No interactions have been reported or no interaction data is currently available. |
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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Drug descriptions are provided by MedlinePlus.