Wahoo - Aricept (Donepezil) Interaction
Herbal: Wahoo
Also Known As: Euonymus atropurpureus, Arrowwood, Bitter Ash, Bleeding Heart, Bursting Heart, Eastern Burning Bush, Fish Wood, Fusain, Fusanum, Fusoria, Gadrose, Gatten, Gatter, Indian Arrowroot, Indian Arrowwood, Pegwood, Pigwood, Prickwood, Skewerwood, Spindle Tree
Drug: Donepezil
Brand names:
Aricept, Adlarity
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Apr 13, 2024
Interaction Details
There were no interactions found between Donepezil and Wahoo. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Wahoo Overview
Euonymus atropurpureus, commonly known as Eastern Wahoo, is a deciduous shrub or small tree native to North America. It is commonly found in forests, along streams, and in other moist, shady areas.
Euonymus atropurpureus is commonly used in traditional medicine to treat a variety of ailments, including digestive problems, respiratory infections, and skin irritations. Wahoo is generally considered poisonous and supplements containing wahoo must be prepared carefully. The seeds of the plant can cause serious adverse effects, such as bloody diarrhea, fever, shortness of breath, circulatory problems, unconsciousness, and convulsions. The specific poisonous component of Euonymus atropurpureus isn't known, but it's likely from the cardioactive steroids, known as cardenolides, or alkaloids the plant contains.
Donepezil Overview
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Donepezil is used to treat dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and may cause changes in mood and personality) in people who have Alzheimer's disease (AD; a brain disease that slowly destroys the memory and the ability to think, learn, communicate and handle daily activities). Donepezil is in a class of medications called cholinesterase inhibitors. It improves mental function (such as memory, attention, the ability to interact with others, speak, think clearly, and perform regular daily activities) by increasing the amount of a certain naturally occurring substance in the brain. Donepezil may improve the ability to think and remember or slow the loss of these abilities in people who have AD. However, donepezil will not cure AD or prevent the loss of mental abilities at some time in the future.
Wahoo - More Interactions
Wahoo interacts with 133 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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