Interaction Details

There were no interactions found between Denosumab and Whey Protein. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Denosumab and Whey Protein? Ask Dr. Brian Staiger about it by contacting him directly.

Whey Protein Overview

Whey Protein Whey protein is a type of protein derived from cow's milk. Specifically, whey comes from the cheesemaking process. Enzymes are added to milk, which separates the milk into cheese curds and liquid whey. Whey is a complete protein, meaning that it contains all nine essential amino acids that the body needs but cannot produce on its own. Whey protein is often used as a supplement to help build and repair muscle tissue, and it is popular among athletes and bodybuilders. There are three main types of whey protein: concentrate, isolate, and hydrolysate. The concentrate contains a higher amount of lactose (milk sugar) and fat, while isolate is a purer form of protein that contains less lactose and fat. Hydrolysate is a predigested form of whey protein that is easier for the body to absorb. Whey protein is often consumed in the form of powders, shakes, and bars, and it can be mixed with water, milk, or other beverages. Drug interactions with whey protein typically result due to the calcium content of whey, which can decrease absorption of some drugs, including many classes of antibiotics.
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Denosumab Overview

  • Denosumab injection (Prolia) is used

    • to treat osteoporosis (a condition in which the bones become thin and weak and break easily) in women who have undergone menopause (''change of life;'' end of menstrual periods) who have an increased risk for fractures (broken bones) or who cannot take or did not respond to other medication treatments for osteoporosis.

    • to treat men who have an increased risk for fractures (broken bones) or who cannot take or did not respond to other medication treatments for osteoporosis.

    • treat osteoporosis that is caused by corticosteroid medications in men and women who will be taking corticosteroid medications for at least 6 months and have an increased risk for fractures or who cannot take or did not respond to other medication treatments for osteoporosis.

    • to treat bone loss in men who are being treated for prostate cancer with certain medications that cause bone loss,

    • to treat bone loss in women with breast cancer who are receiving certain medications that increase their risk for fractures.

  • Denosumab injection (Xgeva) is used

    • to reduce the risk of fractures in people who have multiple myeloma (cancer that begins in the plasma cells and causes bone damage), and in people who have certain types of cancer that began in another part of the body but has spread to the bones.

    • in adults and some adolescents to treat giant cell tumor of bone (GCTB; a type of bone tumor) that cannot be treated with surgery.

    • to treat high calcium levels that are caused by cancer in people who did not respond to other medications.

    Denosumab injection is in a class of medications called RANK ligand inhibitors. It works to prevent bone loss by blocking a certain receptor in the body to decrease bone breakdown. It works to treat GCTB by blocking a certain receptor in the tumor cells which slows the tumor growth. It works to treat high calcium levels by decreasing bone breakdown as the breakdown of bones releases calcium.

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Whey Protein - More Interactions

Whey Protein interacts with 52 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Ask A Pharmacist About Your Herbal Questions!

Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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