1,3-dmba - Harvoni (Ledipasvir, Sofosbuvir) Interaction

Herbal: 1,3-dmba

Drug: Ledipasvir, Sofosbuvir
Brand names: Harvoni

Medical Content Editor
Last updated Apr 13, 2024

Interaction Details

There were no interactions found between Ledipasvir, Sofosbuvir and 1,3-dmba. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.

Still looking for more information about combining Ledipasvir, Sofosbuvir and 1,3-dmba? Ask Dr. Brian Staiger about it by contacting him directly.

1,3-dmba Overview

1,3-DMBA, also known as 1,3-dimethylbutylamine, is a chemical present in certain supplements advertised for enhancing athletic performance and aiding in weight loss. While some products claim to derive 1,3-DMBA from pouchong tea or Coreopsis tinctoria, the levels found in these supplements far exceed natural quantities, suggesting synthetic production. Consequently, the US FDA has classified supplements containing 1,3-DMBA as adulterated, and the World Anti-Doping Agency prohibits their use. When taken orally, 1,3-DMBA is considered potentially unsafe due to its stimulant and vasoconstrictive properties, similar to those of 1,3-DMAA, a synthetic stimulant associated with severe side effects such as lactic acidosis, myocardial infarction, stroke, and even death. As a result, it is strongly recommended to avoid oral consumption of 1,3-DMBA.
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Ledipasvir, Sofosbuvir Overview

  • The combination of ledipasvir and sofosbuvir is used alone or in combination with ribavirin (Copegus, Rebetol, Ribasphere, others) to treat certain types of chronic hepatitis C (an ongoing viral infection that damages the liver) in adults and children 3 years of age and older. Sofosbuvir is in a class of antiviral medications called nucleotide polymerase inhibitors. It works by decreasing the amount of hepatitis C virus (HCV) in the body. Ledipasvir is in a class of antiviral medications called HCV NS5A inhibitors. It works by stopping the virus that causes hepatitis C from spreading inside the body.

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1,3-dmba - More Interactions

1,3-dmba interacts with 318 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Dr. Brian Staiger, PharmD

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Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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