Interaction Details

Modafinil is classified as belonging to the following category: Stimulant Drugs

Theoretically, combining 1,3-DMBA with other stimulant drugs might increase the risk of cardiovascular toxicity.
Animal research shows that 1,3-DMBA has stimulant effects, such as increasing blood pressure and heart rate.

Interaction Rating

Moderate

Likelihood of Occurrence

Possible

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists

References

  • SWANSON EE, CHEN KK. Comparison of pressor action of alicyclic derivatives of aliphatic amines. J Pharmacol Exp Ther. 1948 Aug;93(4):423-9.

1,3-dmba Overview

1,3-DMBA, also known as 1,3-dimethylbutylamine, is a chemical present in certain supplements advertised for enhancing athletic performance and aiding in weight loss. While some products claim to derive 1,3-DMBA from pouchong tea or Coreopsis tinctoria, the levels found in these supplements far exceed natural quantities, suggesting synthetic production. Consequently, the US FDA has classified supplements containing 1,3-DMBA as adulterated, and the World Anti-Doping Agency prohibits their use. When taken orally, 1,3-DMBA is considered potentially unsafe due to its stimulant and vasoconstrictive properties, similar to those of 1,3-DMAA, a synthetic stimulant associated with severe side effects such as lactic acidosis, myocardial infarction, stroke, and even death. As a result, it is strongly recommended to avoid oral consumption of 1,3-DMBA.
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Modafinil Overview

  • Modafinil is used to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness) or shift work sleep disorder (sleepiness during scheduled waking hours and difficulty falling asleep or staying asleep during scheduled sleeping hours in people who work at night or on rotating shifts). Modafinil is also used along with breathing devices or other treatments to prevent excessive sleepiness caused by obstructive sleep apnea/hypopnea syndrome (OSAHS; a sleep disorder in which the patient briefly stops breathing or breathes shallowly many times during sleep and therefore doesn't get enough restful sleep). Modafinil is in a class of medications called wakefulness promoting agents. It works by changing the amounts of certain natural substances in the area of the brain that controls sleep and wakefulness.

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1,3-dmba - More Interactions

1,3-dmba interacts with 319 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

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