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Modafinil

Modafinil is a wakefulness-promoting medicine for adults with excessive sleepiness from narcolepsy, obstructive sleep apnea (OSA), or shift work disorder.

Brand name Provigil
Drug class Sympathomimetic-like Agent
Rx Schedule CIV Form 1
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 2, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 38 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

✓No current FDA shortage listed · checked Oct 5, 2026
Modafinil at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

Modafinil (Provigil), on the U.S. market since about 1998 and available as a generic, helps adults stay awake when narcolepsy, obstructive sleep apnea or shift work disorder causes excessive sleepiness, and it is a common first choice for narcolepsy that acts somewhat like a stimulant, possibly by blocking the brain’s recycling of dopamine. Most people tolerate it well, and headache is the side effect most notice, sometimes with nausea, nervousness or trouble sleeping. Watch for rash above all, and stop it and call your doctor at the first sign, since serious reactions such as Stevens-Johnson syndrome (a severe skin and mucous membrane reaction) have occurred.

Clinical pearls

  • It can make hormonal birth control less reliable, so use backup contraception during treatment and for one month after stopping.
  • For shift work disorder, take it about an hour before your shift; otherwise take it in the morning to protect sleep.
  • If you have sleep apnea, keep using your CPAP machine, because modafinil treats the sleepiness, not the blocked airway.
  • Modafinil is a Schedule IV controlled substance, so refills are limited by law; keep it secured and never share it.
How you get itPrescription only
Comes asTablet
Earliest FDA record1998
Companies listing it with the FDA21
FDA label last updatedDec 19, 2017
FDA’s strongest warning (boxed)None on the label

Patient information guide A plain-language walkthrough of Modafinil, written from its FDA label.

What Modafinil is used for

▾

Modafinil is used to improve wakefulness in adults with excessive sleepiness from these conditions:

  • Narcolepsy (Provigil and modafinil tablets)
  • Obstructive sleep apnea, to treat the sleepiness only and not the airway blockage (Provigil and modafinil tablets)
  • Shift work disorder (Provigil and modafinil tablets)

How Modafinil works

▾

The exact way modafinil promotes wakefulness is unknown. It acts somewhat like stimulants such as amphetamine and methylphenidate, though its profile is not identical. In lab studies, it binds to the dopamine transporter and slows dopamine reuptake. This raises dopamine levels in some brain regions in animals.

Modafinil also produces stimulant-like effects on mood, thinking, and perception in people, and it has reinforcing properties.

Modafinil dosage

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Modafinil tablets (Provigil or generic) are taken by mouth once a day.

  • Narcolepsy or OSA: taken in the morning.
  • Shift work disorder: taken about one hour before your shift.
  • Severe liver problems: the dose is reduced to half.
  • Older adults: a lower dose may be considered.

Follow your prescriber's directions and your label.

Dosing details from the FDA-approved label

From the Modafinil prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Narcolepsy or Obstructive Sleep Apnea (OSA)
    • 200 mg taken orally once a day as a single dose in the morning
    • Maximum: Doses up to 400 mg/day, given as a single dose, have been well tolerated, but there is no consistent evidence that this dose confers additional benefit beyond that of the 200 mg/day dose
  • Shift Work Disorder (SWD)
    • 200 mg taken orally once a day as a single dose approximately 1 hour prior to the start of their work shift
  • Patients with severe hepatic impairment
    • Dosage should be reduced to one-half of that recommended for patients with normal hepatic function
    • Severe hepatic impairment
  • Geriatric patients
    • Consideration should be given to the use of lower doses and close monitoring
    • Age-related adjustment
Read the label’s full dosing text

2 DOSAGE AND ADMINISTRATION The recommended dosage of modafinil tablets for each indication are as follows: • Narcolepsy or OSA: 200 mg once a day in the morning. (2.1) • SWD: 200 mg once a day, taken approximately one hour prior to start of the work shift (2.2) • Severe Hepatic Impairment: reduce dose to half the recommended dose. (2.3, 12.3) • Geriatric Patients: consider lower dose. (2.4, 12.3) 2.1 Dosage in Narcolepsy and Obstructive Sleep Apnea (OSA) The recommended dosage of modafinil tablets for patients with narcolepsy or OSA is 200 mg taken orally once a day as a single dose in the morning. Doses up to 400 mg/day, given as a single dose, have been well tolerated, but there is no consistent evidence that this dose confers additional benefit beyond that of the 200 mg/day dose [see Clinical Pharmacology (12.3) and Clinical Studies (14.1 , 14.2 )]. 2.2 Dosage in Shift Work Disorder (SWD) The recommended dosage of modafinil tablets for patients with SWD is 200 mg taken orally once a day as a single dose approximately 1 hour prior to the start of their work shift. 2.3 Dosage Modifications in Patients with Severe Hepatic Impairment In patients with severe hepatic impairment, the dosage of modafinil tablets should be reduced to one-half of that recommended for patients with normal hepatic function [see Use in Specific Populations (8.6) and Clinical Pharmacology (12.3) ]. 2.4 Use in Geriatric Patients Consideration should be given to the use of lower doses and close monitoring in geriatric patients [see Use in Specific Populations (8.5)] .

2.1 Dosage in Narcolepsy and Obstructive Sleep Apnea (OSA) The recommended dosage of modafinil tablets for patients with narcolepsy or OSA is 200 mg taken orally once a day as a single dose in the morning. Doses up to 400 mg/day, given as a single dose, have been well tolerated, but there is no consistent evidence that this dose confers additional benefit beyond that of the 200 mg/day dose [see Clinical Pharmacology (12.3) and Clinical Studies (14.1 , 14.2 )].

2.2 Dosage in Shift Work Disorder (SWD) The recommended dosage of modafinil tablets for patients with SWD is 200 mg taken orally once a day as a single dose approximately 1 hour prior to the start of their work shift.

Excerpted — the section continues on the label. Read the full Dosage and Administration section on DailyMed →

Modafinil side effects

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Modafinil is generally well tolerated, and most side effects are mild to moderate. Common ones include:

Common side effects

  • Headache
  • Nausea
  • Nervousness
  • Anxiety
  • Trouble sleeping (insomnia)
  • Dizziness
  • Diarrhea
  • Runny or stuffy nose (rhinitis)
  • Back pain
  • Indigestion

When to get medical help

  • Get help right away if you develop a rash. Serious rashes, including Stevens-Johnson syndrome, have occurred. Stop the medicine at the first sign of rash unless a doctor says it is not drug-related.
  • Seek emergency care for swelling of the face, lips, or throat, or trouble breathing (angioedema or anaphylaxis).
  • Call your doctor about signs of a multi-organ allergic reaction.
  • Call your doctor if you develop new or worsening psychiatric symptoms, such as depression, mania, or psychosis.
  • Tell your doctor if you still feel sleepy. Avoid driving or other risky activities if you do.
  • Report chest pain, especially if you have heart disease.

Modafinil warnings and precautions

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  • Serious rash: This includes Stevens-Johnson syndrome and has led to hospitalization. Stop modafinil at the first sign of rash unless it is clearly not drug-related.
  • Allergic reactions: Angioedema, anaphylaxis, and multi-organ hypersensitivity reactions can occur. Stop the medicine if suspected.
  • Persistent sleepiness: Sleepiness may continue. Your doctor will check often, and you may need to avoid driving or other dangerous activities.
  • Psychiatric symptoms: Use caution with a history of psychosis, depression, or mania.
  • Heart disease: Closer monitoring may be needed.

Modafinil interactions

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Modafinil can change the levels of other medicines in your body.

  • Hormonal birth control: may work less well. Use backup contraception during treatment and for one month after.
  • Cyclosporine: levels may fall.
  • Midazolam and triazolam: may be cleared faster.
  • Phenytoin, diazepam, propranolol, omeprazole, clomipramine: may stay in the body longer.
  • Tricyclic antidepressants and SSRIs: levels may rise in people lacking the CYP2D6 enzyme.
  • Warfarin: INR may need more frequent checks.
  • MAO inhibitors: use with caution.

Interactions listed in the FDA-approved label

From the Modafinil prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.

  • CYP3A4/5 substrates (e.g., steroidal contraceptives, cyclosporine, midazolam, triazolam): Clearance of these drugs may be increased by modafinil via induction of metabolic enzymes, resulting in lower systemic exposure. Dosage adjustment of these drugs should be considered when used concomitantly with modafinil.
  • Steroidal contraceptives (e.g., ethinyl estradiol): The effectiveness of steroidal contraceptives may be reduced when used with modafinil and for one month after discontinuation of therapy. Use alternative or concomitant methods of contraception while taking modafinil and for one month after discontinuation of modafinil treatment.
  • Cyclosporine: Blood levels of cyclosporine may be reduced when used with modafinil. Consider monitoring circulating cyclosporine concentrations and appropriate dosage adjustment for cyclosporine.
  • CYP2C19 substrates (e.g., phenytoin, diazepam, propranolol, omeprazole, clomipramine): Elimination of these drugs may be prolonged by modafinil via inhibition of metabolic enzymes, with resultant higher systemic exposure. Dose adjustments of these drugs may be necessary when used concomitantly with modafinil.
  • CYP2D6 substrates with ancillary CYP2C19 elimination (tricyclic antidepressants, SSRIs) in CYP2D6-deficient individuals: Levels of these drugs may be increased by co-administration of modafinil. Dose adjustments of these drugs may be necessary when used concomitantly with modafinil.
Read the label’s full interactions text

7 DRUG INTERACTIONS Effects of Modafinil Tablets on CYP3A4/5 Substrates The clearance of drugs that are substrates for CYP3A4/5 (e.g., steroidal contraceptives, cyclosporine, midazolam, and triazolam) may be increased by modafinil tablets via induction of metabolic enzymes, which results in lower systemic exposure. Dosage adjustment of these drugs should be considered when these drugs are used concomitantly with modafinil tablets [see Clinical Pharmacology (12.3) ]. The effectiveness of steroidal contraceptives may be reduced when used with modafinil tablets and for one month after discontinuation of therapy. Alternative or concomitant methods of contraception are recommended for patients taking steroidal contraceptives (e.g., ethinyl estradiol) when treated concomitantly with modafinil tablets and for one month after discontinuation of modafinil tablets treatment. Blood levels of cyclosporine may be reduced when used with modafinil tablets. Monitoring of circulating cyclosporine concentrations and appropriate dosage adjustment for cyclosporine should be considered when used concomitantly with modafinil tablets. Effects of Modafinil Tablets on CYP2C19 Substrates Elimination of drugs that are substrates for CYP2C19 (e.g., phenytoin, diazepam, propranolol, omeprazole, and clomipramine) may be prolonged by modafinil tablets via inhibition of metabolic enzymes, with resultant higher systemic exposure. In individuals deficient in the CYP2D6 enzyme, the levels of CYP2D6 substrates which have ancillary routes of elimination through CYP2C19, such as tricyclic antidepressants and selective serotonin reuptake inhibitors, may be increased by co-administration of modafinil tablets. Dose adjustments of these drugs and other drugs that are substrates for CYP2C19 may be necessary when used concomitantly with modafinil tablets [see Clinical Pharmacology (12.3) ].

Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →

Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.

Before taking Modafinil

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  • Do not use if allergic to modafinil or armodafinil.
  • Tell your doctor about any history of psychosis, depression, or mania.
  • Tell your doctor about heart disease.
  • Severe liver problems call for a lower dose.
  • Older adults may need a lower dose.
  • Pregnancy: use only if the benefit justifies the risk.
  • Breastfeeding: unknown if it passes into milk, so use caution.
  • Not approved for children, who have had serious rashes.

Modafinil overdose

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Too much modafinil can cause insomnia, restlessness, confusion, agitation, hallucinations, nausea, diarrhea, fast or slow heartbeat, high blood pressure, and chest pain. There is no specific antidote, and care is mainly supportive with heart monitoring. Contact a poison-control center for any overdose.

What Modafinil does in the body

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Modafinil promotes wakefulness, though how is unknown. It inhibits dopamine reuptake in lab studies. In humans it can also cause psychoactive and euphoric effects, and changes in mood, perception, and thinking, like other CNS stimulants.

How your body processes Modafinil

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Modafinil tablets are absorbed readily, with peak levels about 2 to 4 hours after a dose. Steady levels are reached in 2 to 4 days of dosing. The effective half-life is about 15 hours. About 90% is broken down mainly by the liver, and the metabolites leave mostly through the urine.

How to store Modafinil

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Store at 20º to 25ºC (68º to 77ºF) . Dispense in a tight container.

Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

197

Supplements & herbs that interact with Modafinil

197 supplements and herbal products have documented interactions with Modafinil in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 8
  • Moderate · 150
  • Minor · 39
Every supplement checked against Modafinil — ranked by severity The full interaction hub: 8 major · 150 moderate · 39 minor · every one linked to its full report. Check Modafinil against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

Modafinil: pharmacist answers to common questions

Quick, plain-English answers to the questions patients ask most about Modafinil — the kind of thing our pharmacy team would talk through with you at the counter.

What is modafinil for?

▾
It helps adults stay awake when they have excessive sleepiness from narcolepsy, obstructive sleep apnea, or shift work disorder. In sleep apnea, it treats the sleepiness but not the breathing problem, so keep using treatments like CPAP if you have them.

When should I take it?

▾
Take it once a day by mouth. For narcolepsy or sleep apnea, take it in the morning. For shift work disorder, take it about an hour before your shift starts. Follow your prescription label.

What side effects should I expect?

▾
Common ones are headache, nausea, nervousness, anxiety, trouble sleeping, dizziness, and diarrhea. Most are mild to moderate. Let me know if they bother you or don't go away.

Is there anything I should call my doctor about right away?

▾
Yes. Stop the medicine and get help if you see any rash, or swelling of your face, lips, or throat. Also call if you notice new depression, mania, or odd thinking, or if you get chest pain.

Does it affect my birth control?

▾
It can. Modafinil may make hormonal birth control less effective, and this can last for a month after you stop. Use a backup or additional method during that time.

Can I take it if I'm pregnant?

▾
Talk to your doctor first. Animal studies showed possible harm, and there are no good studies in pregnant women. It should only be used if the benefit outweighs the risk.

Is Modafinil available over the counter?

▾
No. Modafinil is a prescription medicine: every Modafinil product listed with the FDA is prescription only, so it is not sold over the counter. Your prescriber decides whether it is appropriate for you, and your pharmacist dispenses it.

Is Modafinil a controlled substance?

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Yes — Modafinil is a federally controlled substance (Schedule IV) in the United States, so how it is prescribed, refilled and dispensed is regulated by the DEA.

When was Modafinil first available?

▾
The earliest FDA record we hold for Modafinil is from 1998: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Modafinil was first used.

Who makes Modafinil?

▾
21 companies currently list Modafinil products in the FDA's NDC Directory, including Aphena Pharma Solutions - Tennessee, LLC, Bryant Ranch Prepack, Golden State Medical Supply, Inc.. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

More about Modafinil on HelloPharmacist

Detailed data & references for Modafinil Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

Modafinil forms and strengths (how it comes)

Modafinil is available in 1 form. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Tablet

By mouth
Brands Provigil
How this form is used
What it may be used for
  • Provigil tablets are used to improve wakefulness in adults with excessive sleepiness from narcolepsy, OSA, or shift work disorder.
  • Modafinil tablets are used to improve wakefulness in adults with excessive sleepiness from narcolepsy, OSA, or shift work disorder.
Important instructions
  • Provigil is taken by mouth once a day, in the morning for narcolepsy or OSA.
  • Provigil is taken about one hour before the work shift for shift work disorder.
  • Modafinil tablets are taken by mouth once a day, in the morning for narcolepsy or OSA, or about one hour before the work shift for shift work disorder.
Available strengths 2 strengths
125 FDA-listed product records ⓘ

Modafinil on the U.S. market: products, makers and brands

How Modafinil appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

21 companies list 57 Modafinil product records with the FDA, mostly as tablet; the earliest marketing or approval year on record is 1998. Brand names on the directory include Provigil; the rest are generics.

1
Dose forms ⓘ
21
Labelers (makers, repackagers, distributors)
2
Brand names
57
FDA-listed product records ⓘ
1998
Earliest FDA record ⓘ

Also listed with the FDA, not a patient dose form: Powder (16) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Aphena Pharma Solutions - Tennessee, LLC11%
Bryant Ranch Prepack9%
Golden State Medical Supply, Inc.9%
Asclemed Usa Inc.7%
Apotex Corp7%
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.5%
Other makers53%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Modafinil is used (Medicaid data)

A general measure of how commonly Modafinil is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Modafinil is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

117,062
Medicaid prescriptions filled (Q1–Q4 2025)
$17.3M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Modafinil prescribed? Of the 1,601 medications we measure, Modafinil ranks #488 by Medicaid prescriptions — more than 70% of them.

Where Modafinil ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5

Utilization by Modafinil product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 200 mg oral tablet is the most-dispensed Modafinil product — about 68% of these Medicaid prescriptions.

modafinil 200 MG Oral Tablet Most dispensed

80,003 Medicaid prescriptions (Q1–Q4 2025) 68% of Modafinil prescriptions shown $13.9M gross reimbursement (before rebates) ≈ $174 per prescription (gross)

Summed across the 17 of 176 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 205324

modafinil 100 MG Oral Tablet

37,059 Medicaid prescriptions (Q1–Q4 2025) 32% of Modafinil prescriptions shown $3.4M gross reimbursement (before rebates) ≈ $92 per prescription (gross)

Summed across the 13 of 93 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 260218

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Modafinil, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 30 of 269 listed Modafinil NDCs with Medicaid activity.

Compare Modafinil products

A representative set of FDA-listed product records for Modafinil — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 57 of 57 products — FDA National Drug Code Directory. See every product, package size and price: browse all 57 Modafinil NDCs →

Modafinil recall history

A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

The FDA’s enforcement reports list no Modafinil recalls since July 2021.

✅No Modafinil recalls on record since July 2021

Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Modafinil RxCUI 30125 1 dose form · 2 strengths
  1. Dose form (SCDF) Oral Tablet RxCUI 372944 In current FDA listings
    Clinical drug / strength (SCD) 100 MG RxCUI 260218 200 MG RxCUI 205324

Look up RxCUI 30125 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

💵 What Modafinil costs pharmacies (NADAC benchmark)

The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.

FormStrengthPharmacy acquisition benchmark
Tablet · Oral 200 mg $0.344 per tablet NDC details & price history
Tablet · Oral 100 mg $0.248 per tablet NDC details & price history
Tablet 100 mg $53.15 per tablet NDC details & price history
Tablet 200 mg $80.35 per tablet NDC details & price history
Why show this? Your out-of-pocket cost depends on insurance, pharmacy markup, and discounts — but the acquisition benchmark tells you whether the medication itself is inexpensive or costly, which strengths cost more per dose, and whether a cash-price quote is in a reasonable range. Each row links to the NDC-level record with its full price history.

Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.

Modafinil brand names

Modafinil is sold under one brand name in the FDA directory — Provigil. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Provigil

Who makes Modafinil: manufacturers and labelers

21 companies list Modafinil products with the FDA. By number of product records, the largest are Aphena Pharma Solutions - Tennessee, LLC, Bryant Ranch Prepack, Golden State Medical Supply, Inc.. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

Aphena Pharma Solutions - Tennessee, LLC 6 Bryant Ranch Prepack 5 Golden State Medical Supply, Inc. 5 Asclemed Usa Inc. 4 Apotex Corp 4 Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. 3 Proficient Rx LP 3 Alembic Pharmaceuticals Inc. 2 Alembic Pharmaceuticals Limited 2 American Health Packaging 2 Aurobindo Pharma Limited 2 AvPAK 2 Bionpharma Inc. 2 Cima Labs Inc. 2 Cephalon, LLC 2 Major Pharmaceuticals 2 Preferred Pharmaceuticals Inc. 2 Rising Pharma Holdings, Inc. 2 Viona Pharmaceuticals Inc 2 Zydus Lifesciences Limited 2 NuCare Pharmaceuticals,Inc. 1

Modafinil drug class (RxNorm)

Modafinil belongs to the Sympathomimetic-like Agent class.

Pharmacologic class Sympathomimetic-like Agent
Drug family (ATC) Centrally acting sympathomimetics

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

Sources for this Modafinil page

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Dec 19, 2017
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Modafinil.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Modafinil after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
38
Finished products in the current FDA directory
57
Companies listing them (makers, repackagers, distributors)
21
FDA labeler codes behind them ⓘ
25
Linked representative label ⓘ
Aphena Pharma Solutions - Tennessee, LLC
Linked label effective
Dec 19, 2017
Composite sections available
25
Linked SPL Set ID
cad4201c-133c-4a61-9d93-3c5e51695430
Linked SPL Document ID
01f751d9-8907-4a54-b2e9-f57a8f150920
Open the linked representative label on DailyMed ↗

How this page is built

HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Aphena Pharma Solutions - Tennessee, LLC is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →