Modafinil
Modafinil is a wakefulness-promoting medicine for adults with excessive sleepiness from narcolepsy, obstructive sleep apnea (OSA), or shift work disorder.
🧬 Where this information comes from Click to expand
The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 38 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →
Modafinil (Provigil), on the U.S. market since about 1998 and available as a generic, helps adults stay awake when narcolepsy, obstructive sleep apnea or shift work disorder causes excessive sleepiness, and it is a common first choice for narcolepsy that acts somewhat like a stimulant, possibly by blocking the brain’s recycling of dopamine. Most people tolerate it well, and headache is the side effect most notice, sometimes with nausea, nervousness or trouble sleeping. Watch for rash above all, and stop it and call your doctor at the first sign, since serious reactions such as Stevens-Johnson syndrome (a severe skin and mucous membrane reaction) have occurred.
Clinical pearls
- It can make hormonal birth control less reliable, so use backup contraception during treatment and for one month after stopping.
- For shift work disorder, take it about an hour before your shift; otherwise take it in the morning to protect sleep.
- If you have sleep apnea, keep using your CPAP machine, because modafinil treats the sleepiness, not the blocked airway.
- Modafinil is a Schedule IV controlled substance, so refills are limited by law; keep it secured and never share it.
Patient information guide A plain-language walkthrough of Modafinil, written from its FDA label.
What Modafinil is used for
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Modafinil is used to improve wakefulness in adults with excessive sleepiness from these conditions:
- Narcolepsy (Provigil and modafinil tablets)
- Obstructive sleep apnea, to treat the sleepiness only and not the airway blockage (Provigil and modafinil tablets)
- Shift work disorder (Provigil and modafinil tablets)
How Modafinil works
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The exact way modafinil promotes wakefulness is unknown. It acts somewhat like stimulants such as amphetamine and methylphenidate, though its profile is not identical. In lab studies, it binds to the dopamine transporter and slows dopamine reuptake. This raises dopamine levels in some brain regions in animals.
Modafinil also produces stimulant-like effects on mood, thinking, and perception in people, and it has reinforcing properties.
Modafinil dosage
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Modafinil tablets (Provigil or generic) are taken by mouth once a day.
- Narcolepsy or OSA: taken in the morning.
- Shift work disorder: taken about one hour before your shift.
- Severe liver problems: the dose is reduced to half.
- Older adults: a lower dose may be considered.
Follow your prescriber's directions and your label.
Dosing details from the FDA-approved label
From the Modafinil prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.
- Narcolepsy or Obstructive Sleep Apnea (OSA)
- 200 mg taken orally once a day as a single dose in the morning
- Maximum: Doses up to 400 mg/day, given as a single dose, have been well tolerated, but there is no consistent evidence that this dose confers additional benefit beyond that of the 200 mg/day dose
- Shift Work Disorder (SWD)
- 200 mg taken orally once a day as a single dose approximately 1 hour prior to the start of their work shift
- Patients with severe hepatic impairment
- Dosage should be reduced to one-half of that recommended for patients with normal hepatic function
- Severe hepatic impairment
- Geriatric patients
- Consideration should be given to the use of lower doses and close monitoring
- Age-related adjustment
Read the label’s full dosing text
2 DOSAGE AND ADMINISTRATION The recommended dosage of modafinil tablets for each indication are as follows: • Narcolepsy or OSA: 200 mg once a day in the morning. (2.1) • SWD: 200 mg once a day, taken approximately one hour prior to start of the work shift (2.2) • Severe Hepatic Impairment: reduce dose to half the recommended dose. (2.3, 12.3) • Geriatric Patients: consider lower dose. (2.4, 12.3) 2.1 Dosage in Narcolepsy and Obstructive Sleep Apnea (OSA) The recommended dosage of modafinil tablets for patients with narcolepsy or OSA is 200 mg taken orally once a day as a single dose in the morning. Doses up to 400 mg/day, given as a single dose, have been well tolerated, but there is no consistent evidence that this dose confers additional benefit beyond that of the 200 mg/day dose [see Clinical Pharmacology (12.3) and Clinical Studies (14.1 , 14.2 )]. 2.2 Dosage in Shift Work Disorder (SWD) The recommended dosage of modafinil tablets for patients with SWD is 200 mg taken orally once a day as a single dose approximately 1 hour prior to the start of their work shift. 2.3 Dosage Modifications in Patients with Severe Hepatic Impairment In patients with severe hepatic impairment, the dosage of modafinil tablets should be reduced to one-half of that recommended for patients with normal hepatic function [see Use in Specific Populations (8.6) and Clinical Pharmacology (12.3) ]. 2.4 Use in Geriatric Patients Consideration should be given to the use of lower doses and close monitoring in geriatric patients [see Use in Specific Populations (8.5)] .
2.1 Dosage in Narcolepsy and Obstructive Sleep Apnea (OSA) The recommended dosage of modafinil tablets for patients with narcolepsy or OSA is 200 mg taken orally once a day as a single dose in the morning. Doses up to 400 mg/day, given as a single dose, have been well tolerated, but there is no consistent evidence that this dose confers additional benefit beyond that of the 200 mg/day dose [see Clinical Pharmacology (12.3) and Clinical Studies (14.1 , 14.2 )].
2.2 Dosage in Shift Work Disorder (SWD) The recommended dosage of modafinil tablets for patients with SWD is 200 mg taken orally once a day as a single dose approximately 1 hour prior to the start of their work shift.
Excerpted — the section continues on the label. Read the full Dosage and Administration section on DailyMed →
Modafinil side effects
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Modafinil is generally well tolerated, and most side effects are mild to moderate. Common ones include:
Common side effects
- Headache
- Nausea
- Nervousness
- Anxiety
- Trouble sleeping (insomnia)
- Dizziness
- Diarrhea
- Runny or stuffy nose (rhinitis)
- Back pain
- Indigestion
When to get medical help
- Get help right away if you develop a rash. Serious rashes, including Stevens-Johnson syndrome, have occurred. Stop the medicine at the first sign of rash unless a doctor says it is not drug-related.
- Seek emergency care for swelling of the face, lips, or throat, or trouble breathing (angioedema or anaphylaxis).
- Call your doctor about signs of a multi-organ allergic reaction.
- Call your doctor if you develop new or worsening psychiatric symptoms, such as depression, mania, or psychosis.
- Tell your doctor if you still feel sleepy. Avoid driving or other risky activities if you do.
- Report chest pain, especially if you have heart disease.
Modafinil warnings and precautions
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- Serious rash: This includes Stevens-Johnson syndrome and has led to hospitalization. Stop modafinil at the first sign of rash unless it is clearly not drug-related.
- Allergic reactions: Angioedema, anaphylaxis, and multi-organ hypersensitivity reactions can occur. Stop the medicine if suspected.
- Persistent sleepiness: Sleepiness may continue. Your doctor will check often, and you may need to avoid driving or other dangerous activities.
- Psychiatric symptoms: Use caution with a history of psychosis, depression, or mania.
- Heart disease: Closer monitoring may be needed.
Modafinil interactions
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Modafinil can change the levels of other medicines in your body.
- Hormonal birth control: may work less well. Use backup contraception during treatment and for one month after.
- Cyclosporine: levels may fall.
- Midazolam and triazolam: may be cleared faster.
- Phenytoin, diazepam, propranolol, omeprazole, clomipramine: may stay in the body longer.
- Tricyclic antidepressants and SSRIs: levels may rise in people lacking the CYP2D6 enzyme.
- Warfarin: INR may need more frequent checks.
- MAO inhibitors: use with caution.
Interactions listed in the FDA-approved label
From the Modafinil prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.
- CYP3A4/5 substrates (e.g., steroidal contraceptives, cyclosporine, midazolam, triazolam): Clearance of these drugs may be increased by modafinil via induction of metabolic enzymes, resulting in lower systemic exposure. Dosage adjustment of these drugs should be considered when used concomitantly with modafinil.
- Steroidal contraceptives (e.g., ethinyl estradiol): The effectiveness of steroidal contraceptives may be reduced when used with modafinil and for one month after discontinuation of therapy. Use alternative or concomitant methods of contraception while taking modafinil and for one month after discontinuation of modafinil treatment.
- Cyclosporine: Blood levels of cyclosporine may be reduced when used with modafinil. Consider monitoring circulating cyclosporine concentrations and appropriate dosage adjustment for cyclosporine.
- CYP2C19 substrates (e.g., phenytoin, diazepam, propranolol, omeprazole, clomipramine): Elimination of these drugs may be prolonged by modafinil via inhibition of metabolic enzymes, with resultant higher systemic exposure. Dose adjustments of these drugs may be necessary when used concomitantly with modafinil.
- CYP2D6 substrates with ancillary CYP2C19 elimination (tricyclic antidepressants, SSRIs) in CYP2D6-deficient individuals: Levels of these drugs may be increased by co-administration of modafinil. Dose adjustments of these drugs may be necessary when used concomitantly with modafinil.
Read the label’s full interactions text
7 DRUG INTERACTIONS Effects of Modafinil Tablets on CYP3A4/5 Substrates The clearance of drugs that are substrates for CYP3A4/5 (e.g., steroidal contraceptives, cyclosporine, midazolam, and triazolam) may be increased by modafinil tablets via induction of metabolic enzymes, which results in lower systemic exposure. Dosage adjustment of these drugs should be considered when these drugs are used concomitantly with modafinil tablets [see Clinical Pharmacology (12.3) ]. The effectiveness of steroidal contraceptives may be reduced when used with modafinil tablets and for one month after discontinuation of therapy. Alternative or concomitant methods of contraception are recommended for patients taking steroidal contraceptives (e.g., ethinyl estradiol) when treated concomitantly with modafinil tablets and for one month after discontinuation of modafinil tablets treatment. Blood levels of cyclosporine may be reduced when used with modafinil tablets. Monitoring of circulating cyclosporine concentrations and appropriate dosage adjustment for cyclosporine should be considered when used concomitantly with modafinil tablets. Effects of Modafinil Tablets on CYP2C19 Substrates Elimination of drugs that are substrates for CYP2C19 (e.g., phenytoin, diazepam, propranolol, omeprazole, and clomipramine) may be prolonged by modafinil tablets via inhibition of metabolic enzymes, with resultant higher systemic exposure. In individuals deficient in the CYP2D6 enzyme, the levels of CYP2D6 substrates which have ancillary routes of elimination through CYP2C19, such as tricyclic antidepressants and selective serotonin reuptake inhibitors, may be increased by co-administration of modafinil tablets. Dose adjustments of these drugs and other drugs that are substrates for CYP2C19 may be necessary when used concomitantly with modafinil tablets [see Clinical Pharmacology (12.3) ].
Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →
Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.
Before taking Modafinil
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- Do not use if allergic to modafinil or armodafinil.
- Tell your doctor about any history of psychosis, depression, or mania.
- Tell your doctor about heart disease.
- Severe liver problems call for a lower dose.
- Older adults may need a lower dose.
- Pregnancy: use only if the benefit justifies the risk.
- Breastfeeding: unknown if it passes into milk, so use caution.
- Not approved for children, who have had serious rashes.
Modafinil overdose
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Too much modafinil can cause insomnia, restlessness, confusion, agitation, hallucinations, nausea, diarrhea, fast or slow heartbeat, high blood pressure, and chest pain. There is no specific antidote, and care is mainly supportive with heart monitoring. Contact a poison-control center for any overdose.
What Modafinil does in the body
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Modafinil promotes wakefulness, though how is unknown. It inhibits dopamine reuptake in lab studies. In humans it can also cause psychoactive and euphoric effects, and changes in mood, perception, and thinking, like other CNS stimulants.
How your body processes Modafinil
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Modafinil tablets are absorbed readily, with peak levels about 2 to 4 hours after a dose. Steady levels are reached in 2 to 4 days of dosing. The effective half-life is about 15 hours. About 90% is broken down mainly by the liver, and the metabolites leave mostly through the urine.
How to store Modafinil
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Store at 20º to 25ºC (68º to 77ºF) . Dispense in a tight container.
Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →
Supplements & herbs that interact with Modafinil
197 supplements and herbal products have documented interactions with Modafinil in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.
- Major · 8
- Moderate · 150
- Minor · 39
Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.
Modafinil: pharmacist answers to common questions
Quick, plain-English answers to the questions patients ask most about Modafinil — the kind of thing our pharmacy team would talk through with you at the counter.
What is modafinil for?
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When should I take it?
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What side effects should I expect?
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Is there anything I should call my doctor about right away?
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Does it affect my birth control?
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Can I take it if I'm pregnant?
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Is Modafinil available over the counter?
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Is Modafinil a controlled substance?
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When was Modafinil first available?
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Who makes Modafinil?
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Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →
More about Modafinil on HelloPharmacist
Modafinil forms and strengths (how it comes)
Modafinil is available in 1 form. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.
Tablet
How this form is used
- Provigil tablets are used to improve wakefulness in adults with excessive sleepiness from narcolepsy, OSA, or shift work disorder.
- Modafinil tablets are used to improve wakefulness in adults with excessive sleepiness from narcolepsy, OSA, or shift work disorder.
- Provigil is taken by mouth once a day, in the morning for narcolepsy or OSA.
- Provigil is taken about one hour before the work shift for shift work disorder.
- Modafinil tablets are taken by mouth once a day, in the morning for narcolepsy or OSA, or about one hour before the work shift for shift work disorder.
Modafinil on the U.S. market: products, makers and brands
How Modafinil appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.
21 companies list 57 Modafinil product records with the FDA, mostly as tablet; the earliest marketing or approval year on record is 1998. Brand names on the directory include Provigil; the rest are generics.
Also listed with the FDA, not a patient dose form: Powder (16) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.
Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
How widely Modafinil is used (Medicaid data)
A general measure of how commonly Modafinil is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.
Think of this as a proxy for how widely Modafinil is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.
How commonly is Modafinil prescribed? Of the 1,601 medications we measure, Modafinil ranks #488 by Medicaid prescriptions — more than 70% of them.
Utilization by Modafinil product
Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.
modafinil 200 MG Oral Tablet Most dispensed
Summed across the 17 of 176 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 205324
modafinil 100 MG Oral Tablet
Summed across the 13 of 93 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 260218
Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.
Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Modafinil, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 30 of 269 listed Modafinil NDCs with Medicaid activity.
Compare Modafinil products
A representative set of FDA-listed product records for Modafinil — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)
| Strength | Route | Manufacturer / Labeler | Category ⓘ | Details |
|---|---|---|---|---|
| 💊Tablet | ||||
| 100 mg | Oral | Alembic Pharmaceuticals Inc. | ANDA | View NDC → |
| 200 mg | Oral | Alembic Pharmaceuticals Inc. | ANDA | View NDC → |
| 100 mg | Oral | Alembic Pharmaceuticals Limited | ANDA | View NDC → |
| 200 mg | Oral | Alembic Pharmaceuticals Limited | ANDA | View NDC → |
| 100 mg | Oral | American Health Packaging | ANDA | View NDC → |
| 200 mg | Oral | American Health Packaging | ANDA | View NDC → |
| 100 mg | Oral | Aphena Pharma Solutions - Tennessee, LLC | ANDA | View NDC → |
| 200 mg | Oral | Aphena Pharma Solutions - Tennessee, LLC | NDA AUTHORIZED GENERIC | View NDC → |
| 200 mg | Oral | Aphena Pharma Solutions - Tennessee, LLC × 4 listings | ANDA | View NDC → |
| 100 mg | Oral | Apotex Corp | NDA | View NDC → |
| 200 mg | Oral | Apotex Corp | NDA | View NDC → |
| 100 mg | Oral | Apotex Corp. | ANDA | View NDC → |
| 200 mg | Oral | Apotex Corp. | ANDA | View NDC → |
| 100 mg | Oral | Asclemed Usa Inc. × 2 listings | ANDA | View NDC → |
| 200 mg | Oral | Asclemed Usa Inc. × 2 listings | ANDA | View NDC → |
| 100 mg | Oral | Aurobindo Pharma Limited | ANDA | View NDC → |
| 200 mg | Oral | Aurobindo Pharma Limited | ANDA | View NDC → |
| 100 mg | Oral | AvPAK | ANDA | View NDC → |
| 200 mg | Oral | AvPAK | ANDA | View NDC → |
| 100 mg | Oral | Bionpharma Inc. | ANDA | View NDC → |
| 200 mg | Oral | Bionpharma Inc. | ANDA | View NDC → |
| 100 mg | Oral | Bryant Ranch Prepack | ANDA | View NDC → |
| 200 mg | Oral | Bryant Ranch Prepack × 4 listings | ANDA | View NDC → |
| 100 mg | Oral | Cephalon, LLC | NDA | View NDC → |
| 200 mg | Oral | Cephalon, LLC | NDA | View NDC → |
| 100 mg | Oral | Cima Labs Inc. | NDA AUTHORIZED GENERIC | View NDC → |
| 200 mg | Oral | Cima Labs Inc. | NDA AUTHORIZED GENERIC | View NDC → |
| 100 mg | Oral | Golden State Medical Supply, Inc. × 2 listings | ANDA | View NDC → |
| 100 mg | Oral | Golden State Medical Supply, Inc. | NDA | View NDC → |
| 200 mg | Oral | Golden State Medical Supply, Inc. | ANDA | View NDC → |
| 200 mg | Oral | Golden State Medical Supply, Inc. | NDA | View NDC → |
| 100 mg | Oral | Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | ANDA | View NDC → |
| 200 mg | Oral | Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. × 2 listings | ANDA | View NDC → |
| 100 mg | Oral | Major Pharmaceuticals | ANDA | View NDC → |
| 200 mg | Oral | Major Pharmaceuticals | ANDA | View NDC → |
| 100 mg | Oral | NuCare Pharmaceuticals,Inc. | ANDA | View NDC → |
| 200 mg | Oral | Preferred Pharmaceuticals Inc. × 2 listings | ANDA | View NDC → |
| 100 mg | Oral | Proficient Rx LP | ANDA | View NDC → |
| 200 mg | Oral | Proficient Rx LP × 2 listings | ANDA | View NDC → |
| 100 mg | Oral | Rising Pharma Holdings, Inc. | ANDA | View NDC → |
| 200 mg | Oral | Rising Pharma Holdings, Inc. | ANDA | View NDC → |
| 100 mg | Oral | Viona Pharmaceuticals Inc | ANDA | View NDC → |
| 200 mg | Oral | Viona Pharmaceuticals Inc | ANDA | View NDC → |
| 100 mg | Oral | Zydus Lifesciences Limited | ANDA | View NDC → |
| 200 mg | Oral | Zydus Lifesciences Limited | ANDA | View NDC → |
Showing 57 of 57 products — FDA National Drug Code Directory. See every product, package size and price: browse all 57 Modafinil NDCs →
Modafinil side effects reported to the FDA (FAERS)
After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Modafinil — a signal of what to watch for, not proof the drug caused it.
Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Modafinil in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.
Modafinil FDA approval history
How Modafinil went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.
Source: Drugs@FDA.
Modafinil recall history
A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.
The FDA’s enforcement reports list no Modafinil recalls since July 2021.
✅No Modafinil recalls on record since July 2021Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.
RxNorm Concept Web — From Ingredient to Every Form and Strength
This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.
RxCUI 30125 1 dose form · 2 strengths
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Dose form (SCDF) Oral Tablet RxCUI 372944In current FDA listings
Look up RxCUI 30125 in the RxCUI Atlas →
RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.
Modafinil supply and shortage status
Whether Modafinil is in short supply in the U.S. right now, plus any shortage history the FDA has on record. A shortage usually reflects a manufacturing or demand issue — not a safety problem with the drug.
Source: openFDA, from the FDA Drug Shortages database.
💵 What Modafinil costs pharmacies (NADAC benchmark)
The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.
| Form | Strength | Pharmacy acquisition benchmark | |
|---|---|---|---|
| Tablet · Oral | 200 mg | $0.344 per tablet | NDC details & price history |
| Tablet · Oral | 100 mg | $0.248 per tablet | NDC details & price history |
| Tablet | 100 mg | $53.15 per tablet | NDC details & price history |
| Tablet | 200 mg | $80.35 per tablet | NDC details & price history |
Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.
Modafinil brand names
Modafinil is sold under one brand name in the FDA directory — Provigil. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.
Who makes Modafinil: manufacturers and labelers
21 companies list Modafinil products with the FDA. By number of product records, the largest are Aphena Pharma Solutions - Tennessee, LLC, Bryant Ranch Prepack, Golden State Medical Supply, Inc.. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.
Modafinil drug class (RxNorm)
Modafinil belongs to the Sympathomimetic-like Agent class.
Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.
Sources for this Modafinil page
Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.
How this page is built
HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Aphena Pharma Solutions - Tennessee, LLC is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →