FDA-filed SPL labeling · retrieved through openFDA

Nystatin and Triamcinolone

Nystatin and Triamcinolone is a combination antifungal and corticosteroid cream or ointment used to treat cutaneous candidiasis (fungal skin infections caused by Candida).

Brand names Myco-Triacet IIMycolog-IIMykacetMytrex FNystatin and Triamcinolone Acetonide
Drug classes ⓘ Corticosteroid
Rx Form 1 Route Topical
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 39 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

At a glance
Linked label effectiveJul 7, 2025
Clinical labels in scope ⓘ39
AvailabilityRx
Earliest approval/marketing year ⓘ1987
FDA-listed product records ⓘ101
Boxed warningNone found in compared labels
How we combine label and product data →
✓No current FDA shortage listed · checked Sep 25, 2026
⭐ Nystatin and Triamcinolone at a glance The quick version — the full detail is in the Patient Information Guide below.
💊
HelloPharmacist Editorial Team Bottom Line
Nystatin and Triamcinolone Acetonide cream and ointment combine an antifungal and a steroid to treat cutaneous candidiasis more effectively than either ingredient alone. Apply it twice daily as directed, avoid covering it with tight dressings, and check in with your doctor if the infection hasn't cleared within 25 days.
How we write & review this content — our editorial policy →

📖 Nystatin and Triamcinolone: Patient Information Guide

A plain-language walkthrough of Nystatin and Triamcinolone — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.

🎯What it's used for▾

Nystatin and Triamcinolone Acetonide is a topical combination product used to treat fungal skin infections. Here are the supported uses:

  • Cutaneous candidiasis — fungal skin infections caused by Candida albicans or other Candida species (supported by both the cream and ointment formulations of Nystatin and Triamcinolone Acetonide)
  • The combination has been shown to provide greater and faster improvement in redness and itching than nystatin or triamcinolone used alone
⚙️How it works▾

Nystatin works by binding to sterols — structural components — in the yeast cell membrane. This destroys the membrane's ability to act as a selective barrier, which kills the fungal cell. It targets Candida species specifically and has no effect on bacteria, viruses, or protozoa. Nystatin is not absorbed through intact skin.

Triamcinolone acetonide is a topical corticosteroid (steroid) that reduces inflammation, relieves itching, and constricts blood vessels in the skin. Together, the two ingredients address both the infection and the uncomfortable symptoms it causes.

💊How it's taken▾

Both the cream and ointment are applied to the affected skin area twice daily — in the morning and in the evening.

  • Cream: Gently and thoroughly massage it into the skin
  • Ointment: Apply a thin film to the affected area
  • Do not use either form under occlusive (airtight) dressings
  • If symptoms have not improved after 25 days, stop using it and contact your doctor
🤒Side effects — in detail▾

Most side effects from this combination product are mild and occur at the site of application. Common ones include:

  • Burning or stinging
  • Itching or irritation
  • Skin dryness
  • Folliculitis (inflamed hair follicles)
  • Acne-like eruptions
  • Hypopigmentation (lightening of skin color)
  • Skin thinning, stretch marks, or miliaria (heat rash) with extended use

Nystatin is well tolerated and rarely causes irritation on its own. If you develop signs of an allergic reaction, a secondary skin infection, or significant skin changes, contact your doctor right away.

⚠️Warnings & precautions▾
  • Do not use with occlusive dressings — covering the skin airtight significantly increases steroid absorption and raises the risk of system-wide side effects
  • Limit duration of use — stop and call your doctor if symptoms haven't improved within 25 days
  • Prolonged use of topical corticosteroids can cause skin thinning, stretch marks, and color changes
  • Inflammation or broken skin increases how much triamcinolone is absorbed into the body
🔀What it interacts with▾

The FDA label for Nystatin and Triamcinolone Acetonide does not list specific drug or food interactions.

    This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.

    📋Before taking it▾
    • Do not use this product if you are allergic to nystatin, triamcinolone acetonide, or any other ingredient in the formulation
    • Tell your doctor or pharmacist about all medications and health conditions before using this product
    • Avoid using occlusive (airtight) bandages or wrap over treated skin areas
    🚑If you take too much▾

    Topical corticosteroids like triamcinolone can be absorbed through the skin in amounts large enough to cause body-wide (systemic) effects if overused. However, acute overdose or serious harm from typical skin application is unlikely. If you are concerned about overuse, contact your doctor or poison control.

    📡Pharmacodynamics — effects in the body▾

    Nystatin targets the cell membranes of Candida yeast, making them unable to function — which stops the infection at its source. Triamcinolone acetonide reduces redness, itching, and swelling through its anti-inflammatory and vasoconstrictive (blood vessel-narrowing) effects. Clinical studies showed patients using the combination had faster and more pronounced clearing of redness and itching than those using either ingredient alone.

    🔬Pharmacokinetics — how your body processes it▾

    Nystatin is not absorbed through intact skin or mucous membranes, so it works locally without entering the bloodstream. Triamcinolone acetonide can be absorbed through the skin — the amount absorbed depends on the condition of the skin, the vehicle (cream vs. ointment), and whether occlusive dressings are used. Once absorbed, it is processed similarly to other corticosteroids: metabolized mainly in the liver and eliminated by the kidneys, with some metabolites also excreted through bile.

    📦How to store it▾

    Store at 20°C to 25°C (68°F to 77°F); . Do not refrigerate and avoid freezing.

    📄 Written from Nystatin and Triamcinolone’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →

    🩺 Pharmacist Counseling Corner

    Quick, plain-English answers to the questions patients ask most about Nystatin and Triamcinolone — the kind of thing our pharmacy team would talk through with you at the counter.

    What exactly is this medication treating? ▾
    This combination cream or ointment treats cutaneous candidiasis — a fungal skin infection caused by Candida yeast. The nystatin kills the yeast, and the triamcinolone steroid helps calm the redness and itching that come with the infection. Studies showed the combination works faster than either ingredient used on its own.
    How do I apply it, and how often? ▾
    Apply it to the affected area twice a day — once in the morning and once in the evening. For the cream, massage it gently and thoroughly into the skin. For the ointment, apply a thin film. Don't wrap the area with tight or airtight bandages after applying — that can push too much of the steroid into your body.
    What side effects might I notice? ▾
    Most people tolerate this medication well. You might notice some mild burning, stinging, or dryness at the spot where you apply it. Less commonly, some people see acne-like bumps or slight skin color changes. If the skin starts thinning, developing stretch marks, or if you notice signs of an allergic reaction like significant swelling or a spreading rash, reach out to your doctor.
    How long should I use it before I know it's working? ▾
    You should start noticing improvement — less redness and itching — within the first several days. The medication should not be used for more than 25 days. If your skin hasn't improved by then, stop applying it and contact your doctor, because the infection may need a different approach.
    Can I use this if I'm allergic to any of the ingredients? ▾
    No — if you've ever had an allergic reaction to nystatin, triamcinolone, or any other ingredient in the product, you should not use it. Tell your doctor or pharmacist about any allergies before you start using it so they can find a safe alternative if needed.
    Is it okay to cover the treated area with a bandage? ▾
    You should avoid covering the treated area with an airtight or occlusive dressing — meaning tight wraps or sealed bandages. That kind of cover-up greatly increases how much of the steroid gets absorbed into your body, which raises the chance of unwanted side effects. A loose, breathable covering is fine if needed, but check with your doctor first.
    Is Nystatin and Triamcinolone available over the counter? ▾
    Nystatin and Triamcinolone is dispensed by prescription according to its FDA labeling, so it isn't sold over the counter. Your prescriber and pharmacist will determine if it's appropriate for you.
    When was Nystatin and Triamcinolone first available? ▾
    Nystatin and Triamcinolone has been available in the United States since at least 1987, based on FDA approval history (Drugs@FDA) and product marketing records.
    Who makes Nystatin and Triamcinolone? ▾
    Nystatin and Triamcinolone is supplied by 30 manufacturers listed in the FDA NDC Directory, including Bryant Ranch Prepack, NuCare Pharmaceuticals,Inc., Preferred Pharmaceuticals Inc..

    💬 Answers drafted from Nystatin and Triamcinolone’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →

    🧰 Keep exploring

    🌿Drug & Supplement CheckerNystatin and Triamcinolone vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Nystatin and Triamcinolone NDCs & costs 🅰️Browse Drugs A–ZLook up any medication

    💊 How Nystatin and Triamcinolone comes

    Nystatin and Triamcinolone is available in 1 form. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

    Topical cream, ointment or gel

    On the skin
    Brands Nystatin and Triamcinolone Acetonide
    How this form is used
    What it may be used for
    • Nystatin and Triamcinolone Acetonide cream and ointment are used to treat cutaneous candidiasis (fungal skin infections caused by Candida yeast)
    • Nystatin and Triamcinolone Acetonide has been shown to clear redness and itching faster than nystatin or triamcinolone used alone
    Important instructions
    • Nystatin and Triamcinolone Acetonide cream: apply to the affected area twice daily (morning and evening), gently massaging it thoroughly into the skin
    • Nystatin and Triamcinolone Acetonide ointment: apply a thin film to the affected area twice daily (morning and evening)
    • Nystatin and Triamcinolone Acetonide cream and ointment should not be used with occlusive (airtight) dressings
    • Discontinue Nystatin and Triamcinolone Acetonide cream or ointment and contact your doctor if symptoms persist after 25 days of therapy
    Available strengths 3 strengths
    100000 mg/g / 1 mg/g 100000 [USP'U]/g / 1 mg/g NYSTATIN 100000 [USP'U]/g; TRIAMCINOLONE ACETONIDE 1 mg/g
    101 FDA-listed product records ⓘ

    📊 Nystatin and Triamcinolone across the U.S. market

    How Nystatin and Triamcinolone appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

    1
    Dose forms ⓘ
    30
    Manufacturers
    1
    Brand names
    101
    FDA-listed product records ⓘ
    1987
    First marketed ⓘ
    Bryant Ranch Prepack31%
    NuCare Pharmaceuticals,Inc.7%
    Preferred Pharmaceuticals Inc.6%
    Remedyrepack Inc.5%
    Preferred Pharmaceuticals Inc., USA4%
    Glenmark Pharmaceuticals Inc., USA4%
    Other makers44%

    Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

    📈 How widely Nystatin and Triamcinolone is used

    A general measure of how commonly Nystatin and Triamcinolone is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

    Think of this as a proxy for how widely Nystatin and Triamcinolone is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

    112,193
    Medicaid prescriptions filled (Q1–Q4 2025)
    $2.1M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

    How commonly is Nystatin and Triamcinolone prescribed? Of the 1,597 medications we measure, Nystatin and Triamcinolone ranks #492 by Medicaid prescriptions — more than 69% of them.

    Where Nystatin and Triamcinolone ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
    Total prescriptions — #492 of 1,597
    #487 Rifaximin 118,294 Rx #488 Modafinil 117,062 Rx #489 Palonosetron Injection 116,599 Rx #490 Cefpodoxime 115,402 Rx #491 Magnesium Sulfate Hept... 113,083 Rx #492 Nystatin and Triamcino... 112,193 Rx #493 Vancomycin Injection 112,053 Rx #494 Atropine 111,807 Rx #495 Lifitegrast Ophthalmic 109,594 Rx #496 Midazolam Nasal Spray 109,459 Rx #497 Digoxin 109,371 Rx

    Utilization by Nystatin and Triamcinolone product

    Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

    The 100000 units/mL / 1 mg/mL topical cream is the most-dispensed Nystatin and Triamcinolone product — about 67% of these Medicaid prescriptions.

    nystatin 100000 UNT/ML / triamcinolone acetonide 1 MG/ML Topical Cream Most dispensed

    74,673 Medicaid prescriptions (Q1–Q4 2025) 67% of Nystatin and Triamcinolone prescriptions shown $1.5M gross reimbursement (before rebates) ≈ $20 per prescription (gross)

    Summed across the 14 of 57 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1053753

    nystatin 100 UNT/MG / triamcinolone acetonide 0.001 MG/MG Topical Ointment

    37,520 Medicaid prescriptions (Q1–Q4 2025) 33% of Nystatin and Triamcinolone prescriptions shown $643,476 gross reimbursement (before rebates) ≈ $17 per prescription (gross)

    Summed across the 18 of 53 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1053697

    Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

    Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Nystatin and Triamcinolone, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 32 of 110 listed Nystatin and Triamcinolone NDCs with Medicaid activity.

    🔍 Compare Nystatin and Triamcinolone products

    A representative set of FDA-listed product records for Nystatin and Triamcinolone — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

    Showing 101 of 101 products — FDA National Drug Code Directory. See every product, package size and price: browse all 101 Nystatin and Triamcinolone NDCs →

    🏷️ Sold under these brand names

    Myco-Triacet II Mycolog-II Mykacet Mytrex F Nystatin and Triamcinolone Acetonide

    🏭 Manufacturers & labelers

    Bryant Ranch Prepack 31 NuCare Pharmaceuticals,Inc. 7 Preferred Pharmaceuticals Inc. 6 Remedyrepack Inc. 5 Preferred Pharmaceuticals Inc., USA 4 Glenmark Pharmaceuticals Inc., USA 4 Padagis Israel Pharmaceuticals Ltd 4 Crown Laboratories 3 Lupin Pharmaceuticals, Inc. 3 RPK Pharmaceuticals, Inc. 3 Macleods Pharmaceuticals Limited 3 Alembic Pharmaceuticals, Inc. 2 Sun Pharmaceutical Industries, Inc. 2 Alembic Pharmaceuticals Inc. 2 Aleor Dermaceuticals Limited 2 Zydus Lifesciences Limited 2 E. Fougera & Co. a division of Fougera Pharmaceuticals Inc. 2 Actavis Pharma, Inc. 2 Torrent Pharmaceuticals Limited 2 Taro Pharmaceuticals U.S.A., Inc. 2 Encube Ethicals Private Limited 1 Dr. Reddy's Laboratories, Inc. 1 Rising Pharmaceuticals, Inc. 1 Ipg Pharmaceuticals, Inc. 1

    …and 6 more on the FDA NDC directory.

    RxNorm drug class

    Nystatin and Triamcinolone belongs to the Corticosteroid class.

    Pharmacologic class Corticosteroid
    Drug family (ATC) Corticosteroids for local oral treatment, Corticosteroids, Corticosteroids, moderately potent (group II)
    How it works Corticosteroid Hormone Receptor Agonists

    Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

    🔬 Where this comes from

    Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

    📄
    FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Jul 7, 2025
    🏭
    Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Nystatin and Triamcinolone.
    📈
    Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
    🚨
    Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
    🧾 Clinical label set — FDA-filed SPL labels retained for Nystatin and Triamcinolone after exact ingredient or ingredient-combination matching and applicable route/form matching
    Clinical labels in scope
    39
    NDC products indexed
    101
    Distinct labelers/manufacturers represented
    30
    Linked representative label ⓘ
    Taro Pharmaceuticals U.S.A., Inc.
    Linked label effective
    Jul 7, 2025
    Composite sections available
    14
    Linked SPL Set ID
    2fd97fc5-cae5-43dd-a3c7-c9a03876153e
    Linked SPL Document ID
    395e7f1c-ecc8-31cf-e063-6294a90aef62
    Open the linked representative label on DailyMed ↗

    How we combine label and product data

    HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 39 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.

    For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Taro Pharmaceuticals U.S.A., Inc. is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.

    This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.