FDA-filed SPL labeling · retrieved through openFDA

Vancomycin

Vancomycin is an antibiotic used to treat serious bacterial infections including blood infections, infective endocarditis, skin and bone infections, lower respiratory tract infections, and — when taken by mouth — C. difficile-associated diarrhea and staphylococcal enterocolitis.

Brand names FirvanqTyzavan

Drug class ⓘ Glycopeptide Antibacterial

Rx Forms 3 Routes Intravenous · Oral · Intravenous, Oral · Intravenous; Oral +1

Reviewed by Dr. Brian Staiger, PharmD, BCPS Last reviewed Jul 10, 2026

🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 57 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

At a glance

Linked label effectiveAug 19, 2026

Clinical labels in scope ⓘ57

AvailabilityRx

Earliest approval/marketing year ⓘ1958

FDA-listed product records ⓘ392

Boxed warningYes

How we combine label and product data →

⚠️Currently in shortage (FDA) 🚨Recall on record · 2

Other forms & routes:

Injection

⭐ Vancomycin at a glance The quick version — the full detail is in the Patient Information Guide below.

💊

HelloPharmacist Editorial Team Bottom Line

Vancomycin is a powerful antibiotic reserved for serious bacterial infections — including MRSA — and for C. diff gut infections when taken by mouth. Because it can affect the kidneys and hearing, your levels and organ function will be monitored closely throughout treatment. Always take it exactly as prescribed, finish the full course, and promptly report any new hearing changes, reduced urination, or skin reactions to your care team.

How we write & review this content — our editorial policy →

⚠️ FDA Boxed Warning — the FDA’s strongest safety alert ▾

One specific injectable formulation of vancomycin — containing the additives PEG 400 and N-acetyl D-alanine (NADA) — should NOT be used during the first or second trimester of pregnancy. In animal studies, these additives (not vancomycin itself) caused fetal bone and heart malformations at high doses. If you need vancomycin during early pregnancy, your doctor should use a different formulation that does not contain these additives. Be sure to tell your doctor if you are pregnant or could become pregnant before receiving any IV vancomycin.

Read the full warning on DailyMed →

📖 Vancomycin: Patient Information Guide

A plain-language walkthrough of Vancomycin — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.

🎯What it's used for▾

Vancomycin is an antibiotic active against serious gram-positive bacterial infections. Approved uses vary by form and route:

IV formulations (including Tyzavan, Vancomycin Injection, and Vancomycin Hydrochloride for Injection): treat septicemia (serious bloodstream infection), infective endocarditis (heart valve infection), skin and skin structure infections, bone infections, and lower respiratory tract infections — in adults and children, including newborns in some formulations
Oral capsules (including Vancocin and Vancomycin Hydrochloride Capsules): treat Clostridioides difficile-associated diarrhea and staphylococcal enterocolitis (including MRSA strains) in adults and pediatric patients under 18
Oral solution/liquid (including Firvanq and Vancomycin Hydrochloride for Oral Solution): treat C. difficile-associated diarrhea and staphylococcal enterocolitis in adults and pediatric patients under 18
The IV form does not work for C. diff or gut infections; the oral form does not work for bloodstream, bone, heart, skin, or lung infections

⚙️How it works▾

Vancomycin kills bacteria by blocking cell wall construction. Bacteria need a strong outer wall to survive; vancomycin binds to key building blocks needed to assemble that wall, causing the bacteria to fall apart. It also disrupts the bacterial cell membrane and interferes with RNA synthesis (how bacteria make proteins). Together, these actions kill the bacteria rather than just slowing their growth.

Vancomycin works only against gram-positive bacteria — a specific class that includes MRSA and certain streptococci — and has no activity against gram-negative bacteria, fungi, or mycobacteria. There is no cross-resistance between vancomycin and other antibiotic classes, which is part of why it's used when other antibiotics have failed.

💊How it's taken▾

How and how often vancomycin is given depends on the form and what's being treated — always follow your prescriber's exact instructions.

IV (intravenous): Given in a healthcare setting, infused slowly into a vein over at least 60 minutes. The frequency depends on kidney function, weight, and the infection being treated. Food timing is not relevant for IV dosing.
Oral capsules (e.g., Vancocin): Taken by mouth several times a day, typically for 7 to 10 days. Can be taken with or without food. Complete the full course even if you feel better.
Oral liquid solution (e.g., Firvanq): Also taken by mouth multiple times a day for 7 to 10 days. The solution is prepared by a pharmacist before dispensing.

If you miss a dose, take it as soon as you remember — unless it's almost time for your next dose. Do not double up. Never switch between oral and IV forms on your own.

🤒Side effects — in detail▾

Side effects vary depending on whether you receive vancomycin by IV or by mouth.

Oral vancomycin (most common, over 10%): nausea, abdominal pain, low potassium (hypokalemia)
Also reported with oral use: vomiting, diarrhea, gas, fever, swelling, headache, fatigue, urinary tract infection
IV and oral (both): kidney injury, hearing loss, ringing in the ears (tinnitus), dizziness, low white blood cell count (neutropenia)
IV-specific: flushing/redness of the face and upper body, low blood pressure, wheezing, chest pain, vein irritation (phlebitis) at the infusion site
Rare but serious: severe allergic reactions (anaphylaxis), life-threatening skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis), cardiac arrest with rapid infusion

Call your doctor or get emergency help right away for signs of kidney problems, hearing changes, severe skin reactions, or any difficulty breathing.

⚠️Warnings & precautions▾

Kidney damage (nephrotoxicity): The biggest risk with vancomycin. Both IV and oral use can cause acute kidney injury. Risk is higher with prolonged use, high doses, existing kidney disease, older age, dehydration, and when combined with other kidney-stressing drugs. Kidney function and vancomycin levels are monitored throughout treatment.
Hearing damage (ototoxicity): Can cause ringing in the ears, hearing loss, or dizziness — sometimes permanently. Higher risk in older patients, those with pre-existing hearing loss, and those also taking aminoglycoside antibiotics.
Severe skin reactions: Rare but potentially life-threatening reactions including toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) have been reported. Stop vancomycin immediately if blistering, peeling skin, or mouth sores appear.
Infusion reactions (IV only): Rapid infusion can cause a dramatic drop in blood pressure, shock, or cardiac arrest. Always infuse over at least 60 minutes. A "vancomycin infusion reaction" (red man syndrome) — flushing, itching, and redness of the face and upper chest — can occur, especially with fast infusion rates.
Low white blood cell count (neutropenia): Reported with both IV and oral use; your doctor may monitor your blood counts during prolonged treatment.
C. diff colitis: Like all antibiotics, vancomycin (when given by IV) can disrupt gut bacteria and trigger C. difficile overgrowth, causing diarrhea or colitis — even weeks after stopping treatment.

🔀What it interacts with▾

Vancomycin has several important drug interactions to be aware of:

Piperacillin/tazobactam (Zosyn): Combining this antibiotic with vancomycin significantly increases the risk of acute kidney injury. Kidney function should be closely monitored.
Anesthetic agents: Using vancomycin around the time of general anesthesia has been associated with skin flushing and histamine-like reactions. When possible, vancomycin is given before anesthetic agents are started.
Aminoglycoside antibiotics (e.g., gentamicin, tobramycin): These drugs are also toxic to the kidneys and ears; using them together with vancomycin raises the risk of both kidney damage and hearing loss.
Other nephrotoxic or ototoxic drugs: Any medication that can stress the kidneys or harm hearing requires closer monitoring of kidney function when used at the same time as vancomycin.

This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.

📋Before taking it▾

Allergy to vancomycin: Do not take it — this is a contraindication. Tell your doctor about any past reactions.
Allergy to corn or corn products: Some IV formulations contain dextrose (derived from corn) and may be contraindicated.
Kidney problems: Vancomycin is cleared almost entirely by the kidneys; doses must be adjusted and function carefully monitored.
Hearing loss: Pre-existing hearing problems increase the risk of ototoxicity; tell your doctor before starting treatment.
Pregnancy (first or second trimester): The specific IV formulation containing PEG 400 and NADA must be avoided; use an alternative vancomycin formulation if treatment is needed. Discuss with your doctor.
Breastfeeding: There is insufficient data on vancomycin levels in breast milk; discuss with your doctor before breastfeeding while on vancomycin.
Older adults (65+): More likely to have reduced kidney function; kidney function should be monitored closely during and after treatment, even if baseline kidney function seems normal.
Children and newborns: Vancomycin is used in pediatric patients with appropriate dose adjustments; infusion reactions may be more severe in children. Serum levels and kidney function should be monitored.
Inflammatory bowel disease: Patients with active gut inflammation may absorb more oral vancomycin into the bloodstream than usual, increasing the risk of systemic side effects.

🚑If you take too much▾

If too much vancomycin is given, supportive care is the main treatment — there is no specific antidote. Vancomycin is not well removed by standard dialysis, though certain advanced filtering techniques (hemofiltration, hemoperfusion with polysulfone resin) may help increase clearance. Contact a Regional Poison Control Center immediately if overdose is suspected.

📡Pharmacodynamics — effects in the body▾

Vancomycin's ability to fight infection is linked to the total amount of drug the body is exposed to over time relative to how resistant the bacteria are — a measure called the AUC/MIC ratio. Essentially, the more drug exposure compared to how much it takes to inhibit the bacteria, the better the outcome. This relationship has been observed in animal models, particularly for MRSA, though the best clinical measure of effectiveness has not been fully established in human trials.

🔬Pharmacokinetics — how your body processes it▾

Vancomycin is given intravenously for most serious infections because it is poorly absorbed when taken by mouth — oral doses stay mostly in the gut, which is exactly what's needed for treating C. diff and gut infections. When given IV, it distributes widely into body fluids including pleural fluid, joint fluid, and urine, but does not easily cross into the spinal fluid unless the brain's protective membranes are inflamed. The drug is about 55% bound to proteins in the blood and is not significantly broken down (metabolized) by the body. It is eliminated almost entirely unchanged through the kidneys, with a normal half-life of 4 to 6 hours — but in people with kidney failure, that can stretch to 7.5 days, making dose adjustments critical. Older adults typically clear the drug more slowly as well.

📦How to store it▾

Store below 25°C (77ºF), in original package.

📄 Written from Vancomycin’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →

Supplements & herbs that interact with Vancomycin

50 supplements and herbal products have documented interactions with Vancomycin in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix

Major · 3
Moderate · 36
Minor · 11

ACTIVATED CHARCOAL Major ASARABACCA Major SIBERIAN COCKLEBUR Major ARISTOLOCHIA Moderate BACILLUS COAGULANS Moderate Bacillus Subtilis Moderate BIFIDOBACTERIUM ANIMALIS SUBSP. LACTIS Moderate BIFIDOBACTERIUM BIFIDUM Moderate +42 more

Every supplement checked against Vancomycin — ranked by severity The full interaction hub: 3 major · 36 moderate · 11 minor · every one linked to its full report. Check Vancomycin against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

Nutrient depletion considerations

Vancomycin has been associated with lower levels of 7 nutrients in the clinical literature. This does not mean a deficiency will occur — it means these may be worth discussing with your pharmacist or healthcare provider, especially with long-term use.

Evidence & significance mix

Higher significance · 6
Moderate · 1

BIOTIN Insignificant Depletion FOLIC ACID Insignificant Depletion RIBOFLAVIN Insignificant Depletion THIAMINE Insignificant Depletion VITAMIN B12 Insignificant Depletion VITAMIN B6 Insignificant Depletion VITAMIN K Moderate Depletion

See the full Vancomycin nutrient depletion report

Educational information from a licensed clinical database (Natural Medicines) — not medical advice. Do not start or stop medications or supplements without professional guidance.

🩺 Pharmacist Counseling Corner

Quick, plain-English answers to the questions patients ask most about Vancomycin — the kind of thing our pharmacy team would talk through with you at the counter.

Why do I need an IV antibiotic — can't I just take a pill? ▾

It depends on what you're being treated for. If you have a serious infection like a bloodstream infection, heart valve infection, or bone infection, the oral form of vancomycin simply doesn't get absorbed into your bloodstream — so it can't reach the infection. The IV form gets the medicine directly where it needs to go. On the flip side, if you're being treated for a C. diff gut infection or staphylococcal enterocolitis, the oral form works because it stays in your gut right where the infection is — and the IV form actually won't work for those.

What should I watch out for while taking vancomycin? ▾

The two biggest things to watch for are changes in your hearing and changes in your urination. If you notice ringing in your ears, muffled hearing, or dizziness, let your doctor know right away — these can be early signs of hearing damage. Also tell your team if you're urinating less than usual or notice swelling, which could signal kidney stress. For the IV form specifically, during or right after the infusion, speak up if you feel flushed, itchy, short of breath, or have chest pain — those are signs the infusion may be going too fast.

Will vancomycin affect my kidneys? ▾

It can, yes — and that's exactly why your doctor will be monitoring your kidney function and blood levels throughout treatment. The risk is higher if you're older, already have kidney issues, are dehydrated, or are taking other drugs that stress the kidneys. If your kidney function changes during treatment, your dose may need to be adjusted or treatment may need to be paused. The good news is that with proper monitoring, your care team can catch any kidney changes early.

I'm pregnant — is vancomycin safe for me? ▾

It depends on which formulation is being considered. There's a specific IV formulation that contains additives called PEG 400 and NADA — and that one should NOT be used in the first or second trimester of pregnancy because those additives caused fetal abnormalities in animal studies. However, other vancomycin formulations without those additives have been used in pregnancy, particularly in the second and third trimesters, without clear evidence of harm in published studies. If you need vancomycin while pregnant, your doctor should use one of those alternative formulations. Always make sure your care team knows you're pregnant.

Do I need to take the full course even if I feel better? ▾

Yes — please finish the full course. With C. diff in particular, stopping early increases the chance the infection comes back. With serious infections treated by IV, stopping early can allow bacteria to survive and potentially come back stronger or more resistant to treatment. Even if you're feeling much better, the bacteria may not be fully cleared yet. If side effects are bothering you, talk to your doctor before stopping — don't just quit on your own.

Are there any other medicines I should avoid while on vancomycin? ▾

Yes, a few important ones. Piperacillin/tazobactam (Zosyn) — a common antibiotic often used in hospitals — raises the risk of kidney injury when combined with vancomycin, so your kidney function will be watched more closely if both are needed. Certain other antibiotics called aminoglycosides can increase the risk of both kidney and hearing damage when used at the same time. Make sure your full medication list — including any over-the-counter drugs or supplements — is shared with your care team so they can watch for any combinations that need extra monitoring.

Is Vancomycin available over the counter? ▾

Vancomycin is dispensed by prescription according to its FDA labeling, so it isn't sold over the counter. Your prescriber and pharmacist will determine if it's appropriate for you.

When was Vancomycin first available? ▾

Vancomycin has been available in the United States since at least 1958, based on FDA approval history (Drugs@FDA) and product marketing records.

Who makes Vancomycin? ▾

Vancomycin is supplied by 65 manufacturers listed in the FDA NDC Directory, including Hikma Pharmaceuticals USA Inc., Hospira, Inc., Xellia Pharmaceuticals USA LLC.

💬 Answers drafted from Vancomycin’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →

🧰 Keep exploring

📊Vancomycin supplement interactions50 checked — ranked by severity 🌿Drug & Supplement CheckerVancomycin vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Vancomycin NDCs & costs 🅰️Browse Drugs A–ZLook up any medication

📊 Detailed data & references for Vancomycin Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here.

💊 How Vancomycin comes

Vancomycin is available in 3 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Injection

By mouth · In the eye · Into a vein

Brands Tyzavan

Available strengths 37 strengths

100 mg/mL 500 mg 500 mg/5 mL 500 mg/10 mL 500 mg/100 mL 513 mg/mg

Show 31 more strengths Show fewer strengths

750 mg 750 mg/15 mL 750 mg/20 mL 750 mg/150 mL 769 mg/mg 1 g 1 g/10 mL 1 g/20 mL 1 g/200 mL 1025 mg/mg 1.25 g 1.25 g/25 mL 1.25 g/30 mL 1.25 g/250 mL 1280 mg/mg 1.5 g 1.5 g/30 mL 1.5 g/300 mL 1540 mg/mg 1.75 g/35 mL 1.75 g/350 mL 2 g/40 mL 2 g/400 mL 5 g 5 g/100 mL 5.13 g/g 10 g 10 g/95 mL 10 g/100 mL 10.25 g/g 100 g

Capsule

By mouth

Available strengths 2 strengths

125 mg 250 mg

Oral solution

By mouth

Available strengths 1 strength

250 mg/5 mL

📊 Vancomycin across the U.S. market

How Vancomycin appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

Dose forms ⓘ

Manufacturers

Brand names

392

FDA-listed product records ⓘ

1958

First marketed ⓘ

Injection

268

Capsule

Oral solution

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Kit (36) · Powder (21) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

40makers

Hikma Pharmaceuticals USA Inc.11%

Hospira, Inc.9%

Xellia Pharmaceuticals USA LLC7%

Mylan Institutional LLC6%

Fresenius Kabi USA, LLC6%

Baxter Healthcare Corporation6%

Other makers55%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

📈 How widely Vancomycin is used

A general measure of how commonly Vancomycin is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Vancomycin is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

145,157

Medicaid prescriptions filled (Q1–Q4 2025)

$14.9M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Vancomycin prescribed? Of the 1,596 medications we measure, Vancomycin ranks #440 by Medicaid prescriptions — more than 72% of them.

Where Vancomycin ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5

Total prescriptions — #440 of 1,596

#435 Secukinumab Injection 149,840 Rx #436 Magnesium Sulfate 148,724 Rx #437 Cannabidiol 148,283 Rx #438 Ketorolac Ophthalmic 148,176 Rx #439 Famotidine Injection 146,638 Rx #440 Vancomycin 145,157 Rx #441 Levodopa and Carbidopa 143,727 Rx #442 Roflumilast 143,447 Rx #443 Scopolamine Transderma... 143,028 Rx #444 Somatropin 142,879 Rx #445 Indomethacin 142,731 Rx

Utilization by Vancomycin product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 1000 mg injection is the most-dispensed Vancomycin product — about 32% of these Medicaid prescriptions.

vancomycin 1000 MG Injection Most dispensed

46,890 Medicaid prescriptions (Q1–Q4 2025) 32% of Vancomycin prescriptions shown $6.4M gross reimbursement (before rebates) ≈ $136 per prescription (gross)

Summed across the 13 of 55 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1807513

vancomycin 125 MG Oral Capsule

27,646 Medicaid prescriptions (Q1–Q4 2025) 19% of Vancomycin prescriptions shown $1.7M gross reimbursement (before rebates) ≈ $61 per prescription (gross)

Summed across the 8 of 30 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 313570

vancomycin 100 MG/ML Injectable Solution

21,223 Medicaid prescriptions (Q1–Q4 2025) 15% of Vancomycin prescriptions shown $2.2M gross reimbursement (before rebates) ≈ $101 per prescription (gross)

Summed across the 10 of 22 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 239209

200 ML vancomycin 5 MG/ML Injection

10,842 Medicaid prescriptions (Q1–Q4 2025) 7% of Vancomycin prescriptions shown $1M gross reimbursement (before rebates) ≈ $93 per prescription (gross)

Summed across the 3 of 8 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1807508

vancomycin 50 MG/ML Injectable Solution

9,039 Medicaid prescriptions (Q1–Q4 2025) 6% of Vancomycin prescriptions shown $715,447 gross reimbursement (before rebates) ≈ $79 per prescription (gross)

Summed across the 8 of 18 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 313572

vancomycin 500 MG Injection

8,244 Medicaid prescriptions (Q1–Q4 2025) 6% of Vancomycin prescriptions shown $657,676 gross reimbursement (before rebates) ≈ $80 per prescription (gross)

Summed across the 8 of 52 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1807516

250 ML vancomycin 5 MG/ML Injection

4,143 Medicaid prescriptions (Q1–Q4 2025) 3% of Vancomycin prescriptions shown $387,529 gross reimbursement (before rebates) ≈ $94 per prescription (gross)

Summed across the 2 of 5 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2387078

300 ML vancomycin 5 MG/ML Injection

3,398 Medicaid prescriptions (Q1–Q4 2025) 2% of Vancomycin prescriptions shown $350,114 gross reimbursement (before rebates) ≈ $103 per prescription (gross)

Summed across the 2 of 5 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2118448

vancomycin 250 MG Oral Capsule

2,408 Medicaid prescriptions (Q1–Q4 2025) 2% of Vancomycin prescriptions shown $343,116 gross reimbursement (before rebates) ≈ $142 per prescription (gross)

Summed across the 4 of 31 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 313571

vancomycin 50 MG/ML Oral Solution

2,364 Medicaid prescriptions (Q1–Q4 2025) 2% of Vancomycin prescriptions shown $323,380 gross reimbursement (before rebates) ≈ $137 per prescription (gross)

Summed across the 8 of 23 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2000134

150 ML vancomycin 5 MG/ML Injection

2,128 Medicaid prescriptions (Q1–Q4 2025) 1% of Vancomycin prescriptions shown $128,677 gross reimbursement (before rebates) ≈ $60 per prescription (gross)

Summed across the 3 of 8 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1807510

vancomycin 750 MG Injection

1,713 Medicaid prescriptions (Q1–Q4 2025) 1% of Vancomycin prescriptions shown $88,082 gross reimbursement (before rebates) ≈ $51 per prescription (gross)

Summed across the 6 of 22 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1807518

vancomycin 1250 MG Injection

1,463 Medicaid prescriptions (Q1–Q4 2025) 1% of Vancomycin prescriptions shown $170,889 gross reimbursement (before rebates) ≈ $117 per prescription (gross)

Summed across the 5 of 16 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2049888

vancomycin 1500 MG Injection

1,199 Medicaid prescriptions (Q1–Q4 2025) <1% of Vancomycin prescriptions shown $256,877 gross reimbursement (before rebates) ≈ $214 per prescription (gross)

Summed across the 4 of 18 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2049890

100 ML vancomycin 5 MG/ML Injection

688 Medicaid prescriptions (Q1–Q4 2025) <1% of Vancomycin prescriptions shown $29,699 gross reimbursement (before rebates) ≈ $43 per prescription (gross)

Summed across the 3 of 8 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1807511

vancomycin 25 MG/ML Oral Solution

686 Medicaid prescriptions (Q1–Q4 2025) <1% of Vancomycin prescriptions shown $75,135 gross reimbursement (before rebates) ≈ $110 per prescription (gross)

Summed across the 6 of 7 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2000127

350 ML vancomycin 5 MG/ML Injection

608 Medicaid prescriptions (Q1–Q4 2025) <1% of Vancomycin prescriptions shown $69,780 gross reimbursement (before rebates) ≈ $115 per prescription (gross)

Summed across the 1 of 4 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2387079

400 ML vancomycin 5 MG/ML Injection

425 Medicaid prescriptions (Q1–Q4 2025) <1% of Vancomycin prescriptions shown $32,855 gross reimbursement (before rebates) ≈ $77 per prescription (gross)

Summed across the 1 of 4 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2118449

vancomycin 1750 MG Injection

33 Medicaid prescriptions (Q1–Q4 2025) <1% of Vancomycin prescriptions shown $9,373 gross reimbursement (before rebates) ≈ $284 per prescription (gross)

Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2688632

vancomycin 2000 MG Injection

17 Medicaid prescriptions (Q1–Q4 2025) <1% of Vancomycin prescriptions shown $4,601 gross reimbursement (before rebates) ≈ $271 per prescription (gross)

Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2688634

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Vancomycin, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 97 of 340 listed Vancomycin NDCs with Medicaid activity.

🔍 Compare Vancomycin products

A representative set of FDA-listed product records for Vancomycin — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Strength	Route	Manufacturer / Labeler	Category ⓘ	Details
💊Capsule
250 mg	Oral	Advanced Rx of Tennessee, LLC	NDA AUTHORIZED GENERIC	View NDC →
125 mg	Oral	Akorn	ANDA	View NDC →
250 mg	Oral	Akorn	ANDA	View NDC →
125 mg	Oral	Alvogen Inc. × 2 listings	ANDA	View NDC →
250 mg	Oral	Alvogen Inc. × 2 listings	ANDA	View NDC →
125 mg	Oral	ANI Pharmaceuticals, Inc. × 2 listings	NDA	View NDC →
125 mg	Oral	ANI Pharmaceuticals, Inc. × 2 listings	NDA AUTHORIZED GENERIC	View NDC →
250 mg	Oral	ANI Pharmaceuticals, Inc. × 2 listings	NDA	View NDC →
250 mg	Oral	ANI Pharmaceuticals, Inc. × 2 listings	NDA AUTHORIZED GENERIC	View NDC →
125 mg	Oral	Bryant Ranch Prepack × 2 listings	ANDA	View NDC →
250 mg	Oral	Bryant Ranch Prepack × 2 listings	ANDA	View NDC →
125 mg	Oral	Cameron Pharmaceuticals × 2 listings	ANDA	View NDC →
250 mg	Oral	Cameron Pharmaceuticals × 2 listings	ANDA	View NDC →
125 mg	Oral	Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. × 3 listings	ANDA	View NDC →
250 mg	Oral	Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. × 3 listings	ANDA	View NDC →
125 mg	Oral	Lupin Pharmaceuticals, Inc. × 2 listings	ANDA	View NDC →
250 mg	Oral	Lupin Pharmaceuticals, Inc. × 2 listings	ANDA	View NDC →
125 mg	Oral	Orient Pharma Co.,Ltd Yunlin Plant	ANDA	View NDC →
250 mg	Oral	Orient Pharma Co.,Ltd Yunlin Plant	ANDA	View NDC →
125 mg	Oral	PAI Holdings, LLC × 2 listings	ANDA	View NDC →
250 mg	Oral	PAI Holdings, LLC × 2 listings	ANDA	View NDC →
125 mg	Oral	PAI Holdings, LLC dba PAI Pharma	ANDA	View NDC →
250 mg	Oral	PAI Holdings, LLC dba PAI Pharma	ANDA	View NDC →
125 mg	Oral	Pharmaceutical Associates, Inc. × 2 listings	ANDA	View NDC →
250 mg	Oral	Pharmaceutical Associates, Inc. × 2 listings	ANDA	View NDC →
125 mg	Oral	Redpharm Drug	NDA AUTHORIZED GENERIC	View NDC →
125 mg	Oral	Redpharm Drug	ANDA	View NDC →
125 mg	Oral	Remedyrepack Inc.	ANDA	View NDC →
125 mg	Oral	Strides Pharma Science Limited	ANDA	View NDC →
250 mg	Oral	Strides Pharma Science Limited	ANDA	View NDC →
💊Injection
500 mg/10 mL	Intravenous	Almaject, Inc. × 2 listings	ANDA	View NDC →
1 g/20 mL	Intravenous	Almaject, Inc. × 2 listings	ANDA	View NDC →
500 mg/10 mL	Intravenous	Athenex Pharmaceutical Division, LLC.	ANDA	View NDC →
1 g/20 mL	Intravenous	Athenex Pharmaceutical Division, LLC.	ANDA	View NDC →
500 mg/10 mL	Intravenous	AuroMedics Pharma LLC	ANDA	View NDC →
1 g/20 mL	Intravenous	AuroMedics Pharma LLC	ANDA	View NDC →
5 g	Intravenous	AuroMedics Pharma LLC	ANDA	View NDC →
10 g	Intravenous	AuroMedics Pharma LLC	ANDA	View NDC →
750 mg	Intravenous, Oral	Avenacy, LLC	NDA	View NDC →
1.25 g	Intravenous, Oral	Avenacy, LLC	NDA	View NDC →
1.5 g	Intravenous, Oral	Avenacy, LLC	NDA	View NDC →
500 mg	Intravenous	BluePoint Laboratories	ANDA	View NDC →
1 g	Intravenous	BluePoint Laboratories	ANDA	View NDC →
5 g	Intravenous	BluePoint Laboratories	ANDA	View NDC →
10 g	Intravenous	BluePoint Laboratories	ANDA	View NDC →
500 mg/10 mL	Intravenous	Camber Pharmaceuticals, Inc.	ANDA	View NDC →
1 g/20 mL	Intravenous	Camber Pharmaceuticals, Inc.	ANDA	View NDC →
500 mg/5 mL	Intravenous	Civica, Inc	ANDA	View NDC →
500 mg/10 mL	Intravenous	Civica, Inc	ANDA	View NDC →
1 g	Intravenous	Civica, Inc	ANDA	View NDC →
1 g/10 mL	Intravenous	Civica, Inc. × 2 listings	ANDA	View NDC →
5 g/100 mL	Intravenous	Civica, Inc.	ANDA	View NDC →
10 g/100 mL	Intravenous	Civica, Inc.	ANDA	View NDC →
500 mg/10 mL	Intravenous	Eugia US LLC × 2 listings	ANDA	View NDC →
1 g/20 mL	Intravenous	Eugia US LLC × 2 listings	ANDA	View NDC →
1.25 g/25 mL	Intravenous	Eugia US LLC	ANDA	View NDC →
1.5 g/30 mL	Intravenous	Eugia US LLC	ANDA	View NDC →
5 g	Intravenous	Eugia US LLC × 2 listings	ANDA	View NDC →
10 g	Intravenous	Eugia US LLC × 2 listings	ANDA	View NDC →
500 mg/10 mL	Intravenous	Eurofarma, Inc.	ANDA	View NDC →
1 g/20 mL	Intravenous	Eurofarma, Inc.	ANDA	View NDC →
500 mg/10 mL	Intravenous	Fresenius Kabi, LLC × 4 listings	ANDA	View NDC →
1 g/20 mL	Intravenous	Fresenius Kabi, LLC × 2 listings	ANDA	View NDC →
10 g/100 mL	Intravenous	Fresenius Kabi, LLC	ANDA	View NDC →
500 mg/10 mL	Intravenous	Fresenius Kabi USA, LLC × 4 listings	ANDA	View NDC →
750 mg/15 mL	Intravenous	Fresenius Kabi USA, LLC × 5 listings	ANDA	View NDC →
1 g/20 mL	Intravenous	Fresenius Kabi USA, LLC × 6 listings	ANDA	View NDC →
5 g/100 mL	Intravenous	Fresenius Kabi USA, LLC × 3 listings	ANDA	View NDC →
10 g/100 mL	Intravenous	Fresenius Kabi USA, LLC × 3 listings	ANDA	View NDC →
500 mg	Intravenous	General Injectables & Vaccines, Inc	ANDA	View NDC →
500 mg/10 mL	Intravenous	Gland Pharma Limited × 2 listings	ANDA	View NDC →
750 mg	Intravenous	Gland Pharma Limited	ANDA	View NDC →
1 g/20 mL	Intravenous	Gland Pharma Limited × 2 listings	ANDA	View NDC →
1.25 g	Intravenous	Gland Pharma Limited	ANDA	View NDC →
1.5 g	Intravenous	Gland Pharma Limited	ANDA	View NDC →
5 g/100 mL	Intravenous	Gland Pharma Limited	ANDA	View NDC →
10 g/100 mL	Intravenous	Gland Pharma Limited	ANDA	View NDC →
500 mg/10 mL	Intravenous	Glenmark Pharmaceuticals Inc., Usa	ANDA	View NDC →
750 mg	Intravenous	Glenmark Pharmaceuticals Inc., Usa	ANDA	View NDC →
1 g/20 mL	Intravenous	Glenmark Pharmaceuticals Inc., Usa	ANDA	View NDC →
1.25 g	Intravenous	Glenmark Pharmaceuticals Inc., Usa	ANDA	View NDC →
1.5 g	Intravenous	Glenmark Pharmaceuticals Inc., Usa	ANDA	View NDC →
500 mg	Intravenous	Henry Schein, Inc. × 3 listings	ANDA	View NDC →
500 mg	Intravenous	Hikma Pharmaceuticals USA Inc.	ANDA	View NDC →
513 mg/mg	Intravenous, Oral	Hikma Pharmaceuticals Usa Inc.	NDA	View NDC →
513 mg/mg	Intravenous; Oral	Hikma Pharmaceuticals Usa Inc.	NDA	View NDC →
750 mg	Intravenous	Hikma Pharmaceuticals USA Inc.	ANDA	View NDC →
769 mg/mg	Intravenous, Oral	Hikma Pharmaceuticals Usa Inc.	NDA	View NDC →
1 g	Intravenous	Hikma Pharmaceuticals USA Inc.	ANDA	View NDC →
1025 mg/mg	Intravenous, Oral	Hikma Pharmaceuticals Usa Inc.	NDA	View NDC →
1025 mg/mg	Intravenous; Oral	Hikma Pharmaceuticals Usa Inc.	NDA	View NDC →
1.25 g	Intravenous	Hikma Pharmaceuticals USA Inc. × 2 listings	ANDA	View NDC →
1280 mg/mg	Intravenous, Oral	Hikma Pharmaceuticals Usa Inc.	NDA	View NDC →
1.5 g	Intravenous	Hikma Pharmaceuticals USA Inc. × 2 listings	ANDA	View NDC →
1540 mg/mg	Intravenous, Oral	Hikma Pharmaceuticals Usa Inc.	NDA	View NDC →
5 g	Intravenous	Hikma Pharmaceuticals USA Inc.	ANDA	View NDC →
5.13 g/g	Intravenous, Oral	Hikma Pharmaceuticals Usa Inc.	NDA	View NDC →
5.13 g/g	Intravenous; Oral	Hikma Pharmaceuticals Usa Inc.	NDA	View NDC →
10 g	Intravenous	Hikma Pharmaceuticals USA Inc.	ANDA	View NDC →
10.25 g/g	Intravenous, Oral	Hikma Pharmaceuticals Usa Inc.	NDA	View NDC →
10.25 g/g	Intravenous; Oral	Hikma Pharmaceuticals Usa Inc.	NDA	View NDC →
100 mg/mL	Intravenous	Hospira, Inc.	ANDA	View NDC →
500 mg	Intravenous	Hospira, Inc. × 4 listings	ANDA	View NDC →
500 mg/5 mL	Intravenous	Hospira, Inc. × 6 listings	ANDA	View NDC →
500 mg/10 mL	Intravenous	Hospira, Inc. × 7 listings	ANDA	View NDC →
750 mg	Intravenous	Hospira, Inc. × 4 listings	ANDA	View NDC →
1 g	Intravenous	Hospira, Inc. × 6 listings	ANDA	View NDC →
1.5 g	Intravenous	Hospira, Inc. × 3 listings	ANDA	View NDC →
500 mg/10 mL	Intravenous	Meitheal Pharmaceuticals Inc. × 3 listings	ANDA	View NDC →
750 mg/15 mL	Intravenous	Meitheal Pharmaceuticals Inc. × 2 listings	ANDA	View NDC →
1 g/20 mL	Intravenous	Meitheal Pharmaceuticals Inc. × 3 listings	ANDA	View NDC →
5 g/100 mL	Intravenous	Meitheal Pharmaceuticals Inc. × 2 listings	ANDA	View NDC →
10 g/95 mL	Intravenous	Meitheal Pharmaceuticals Inc. × 2 listings	ANDA	View NDC →
500 mg	Intravenous	Xellia Pharmaceuticals USA LLC	ANDA	View NDC →
1 g	Intravenous	Xellia Pharmaceuticals USA LLC	ANDA	View NDC →
10.25 g/g	Intravenous, Oral	Zhejiang Novus Pharma Co., Ltd.	NDA	View NDC →

Showing 200 of 392 products — FDA National Drug Code Directory. See every product, package size and price: browse all 392 Vancomycin NDCs →

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Vancomycin RxCUI 11124 4 dose forms · 21 strengths

Dose form (SCDF) Injectable Solution RxCUI 375983 In current FDA listings
Clinical drug / strength (SCD) 50 MG/ML RxCUI 313572 100 MG/ML RxCUI 239209
Dose form (SCDF) Injection RxCUI 1807507 In current FDA listings
Clinical drug / strength (SCD) 100 ML vancomycin 5 MG/ML RxCUI 1807511 150 ML vancomycin 5 MG/ML RxCUI 1807510 200 ML vancomycin 5 MG/ML RxCUI 1807508 250 MG RxCUI 2049891 250 ML vancomycin 5 MG/ML RxCUI 2387078 300 ML vancomycin 5 MG/ML RxCUI 2118448 350 ML vancomycin 5 MG/ML RxCUI 2387079 400 ML vancomycin 5 MG/ML RxCUI 2118449 500 MG RxCUI 1807516 750 MG RxCUI 1807518 1000 MG RxCUI 1807513 1250 MG RxCUI 2049888 1500 MG RxCUI 2049890 1750 MG RxCUI 2688632 2000 MG RxCUI 2688634
Dose form (SCDF) Oral Capsule RxCUI 374281 In current FDA listings
Clinical drug / strength (SCD) 125 MG RxCUI 313570 250 MG RxCUI 313571
Dose form (SCDF) Oral Solution RxCUI 374282 In current FDA listings
Clinical drug / strength (SCD) 25 MG/ML RxCUI 2000127 50 MG/ML RxCUI 2000134

Look up RxCUI 11124 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

🏷️ Sold under these brand names

Firvanq Tyzavan

🏭 Manufacturers & labelers

Hikma Pharmaceuticals USA Inc. 41 Hospira, Inc. 31 Xellia Pharmaceuticals USA LLC 24 Mylan Institutional LLC 23 Fresenius Kabi USA, LLC 21 Baxter Healthcare Corporation 20 Azurity Pharmaceuticals, Inc 20 Bryant Ranch Prepack 17 Meitheal Pharmaceuticals Inc. 12 Wilshire Pharmaceuticals, Inc. 12 Eugia US LLC 10 ANI Pharmaceuticals, Inc. 10 Sagent Pharmaceuticals 9 Gland Pharma Limited 9 Slate Run Pharmaceuticals, LLC 8 Fresenius Kabi, LLC 7 NorthStar Rx LLC 6 Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. 6 Glenmark Pharmaceuticals Inc., Usa 5 Pharmaceutical Associates, Inc. 4 Civica, Inc. 4 Cameron Pharmaceuticals 4 BluePoint Laboratories 4 Lupin Pharmaceuticals, Inc. 4

…and 16 more on the FDA NDC directory.

RxNorm drug class

Vancomycin belongs to the Glycopeptide Antibacterial class.

Pharmacologic class Glycopeptide Antibacterial

Drug family (ATC) Antibiotics, Glycopeptide antibacterials, Antibiotics

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

septicemia: A serious and life-threatening infection in which bacteria spread through the bloodstream, sometimes called blood poisoning.

infective endocarditis: An infection of the inner lining of the heart chambers and valves, usually caused by bacteria entering the bloodstream.

MRSA: Methicillin-resistant Staphylococcus aureus — a type of staph bacteria that is resistant to many common antibiotics, making it harder to treat.

C. difficile: Clostridioides difficile, a bacterium that can overgrow in the gut — often after antibiotic use — causing diarrhea and potentially serious colon inflammation.

enterocolitis: Inflammation of both the small intestine and colon, often caused by an infection; staphylococcal enterocolitis is caused by Staphylococcus aureus bacteria.

nephrotoxicity: Damage to the kidneys caused by a drug or chemical, which can impair the kidney's ability to filter waste from the blood.

ototoxicity: Damage to the ears — particularly to hearing or balance — caused by a drug or chemical.

glycopeptide antibiotic: A class of antibiotics that kill bacteria by blocking the construction of their cell walls; vancomycin is the most well-known member of this class.

gram-positive bacteria: A category of bacteria identified by their cell wall structure; they tend to retain a purple stain in laboratory tests and include staph and strep species that vancomycin can treat.

gram-negative bacteria: A category of bacteria with a different cell wall structure that vancomycin cannot penetrate or kill.

intravenous (IV): Delivered directly into a vein, allowing a drug to enter the bloodstream immediately.

infusion reaction: A reaction that occurs during or shortly after receiving an IV medication, which can include flushing, itching, low blood pressure, or breathing difficulty.

phlebitis: Inflammation of a vein, often at or near the site of an IV line, causing pain, redness, and swelling.

neutropenia: An abnormally low level of neutrophils (a type of white blood cell), which weakens the body's ability to fight infection.

hypokalemia: An abnormally low level of potassium in the blood, which can cause muscle weakness, cramps, or heart rhythm problems.

tinnitus: A ringing, buzzing, or hissing sound in the ears that has no external source; can be a sign of ear damage.

toxic epidermal necrolysis (TEN): A rare, life-threatening skin reaction where large areas of skin blister and peel away, triggered by drugs or infections.

Stevens-Johnson syndrome (SJS): A serious allergic skin reaction causing painful blistering of the skin and mucous membranes; less extensive than TEN but similarly dangerous.

anaphylaxis: A severe, rapid, and potentially life-threatening allergic reaction affecting the whole body, causing symptoms like throat swelling, a dramatic drop in blood pressure, and difficulty breathing.

AUC/MIC ratio: A measure used in pharmacology that compares how much drug the body is exposed to over time (AUC) with how much drug it takes to stop bacterial growth (MIC); a higher ratio generally means better bacterial killing.

half-life: The time it takes for the body to reduce the concentration of a drug in the blood by half; a longer half-life means the drug stays in the body longer.

renal clearance: The rate at which the kidneys filter and remove a drug from the blood.

excipient: An inactive ingredient added to a drug formulation — such as a preservative or stabilizer — that is not the active medicine itself but can still have biological effects.

PEG 400 (polyethylene glycol): A chemical commonly used as an additive in injectable drug formulations; in animal studies, high doses caused fetal abnormalities, prompting a pregnancy warning for specific vancomycin IV products.

cell wall biosynthesis: The process by which bacteria build and maintain their outer protective wall; vancomycin works by blocking this process.

aminoglycoside: A class of antibiotics (such as gentamicin or tobramycin) used for serious bacterial infections; they can also damage the kidneys and hearing, which is why combining them with vancomycin requires extra monitoring.

piperacillin/tazobactam: A combination antibiotic (brand name Zosyn) commonly used in hospitals that, when given alongside vancomycin, increases the risk of kidney injury.

pseudomembranous colitis: A serious inflammation of the colon, often caused by C. difficile overgrowth after antibiotic use, which can cause severe diarrhea and in rare cases be fatal.

interstitial nephritis: A type of kidney inflammation affecting the spaces between the kidney tubules, which can be triggered by certain drugs including vancomycin and leads to reduced kidney function.

acute tubular necrosis: Damage and death of the tubule cells inside the kidney — often caused by toxins or reduced blood flow — that can lead to acute kidney failure.

hemofiltration: A kidney-replacement therapy that filters blood through a membrane, similar to dialysis but using a different mechanism; can help remove some drugs from the body in overdose situations.

contraindication: A specific situation, condition, or factor that makes a particular treatment dangerous or inadvisable to use.

vancomycin infusion reaction: A reaction to rapid IV vancomycin infusion causing flushing, redness, and itching of the face, neck, and upper chest — sometimes called 'red man syndrome.'

pharmacokinetics: The study of how the body absorbs, distributes, breaks down, and eliminates a drug over time.

pharmacodynamics: The study of what a drug does to the body — including its effects and how those effects relate to the drug's concentration.

glomerular filtration: The process by which the kidneys filter waste products and drugs out of the blood; vancomycin is primarily eliminated this way.

serum concentration: The amount of a drug measured in the liquid part of the blood; used to monitor whether a drug is at a safe and effective level.

gram-positive: A classification for bacteria whose cell walls have a specific structure that retains a particular laboratory dye; vancomycin is effective against this group of bacteria.

aminoglycoside synergy: The enhanced antibacterial effect that results from combining vancomycin with an aminoglycoside antibiotic — the two drugs working together more powerfully than either alone.

contraindicated: Should not be used in that situation, because the risk is considered too high.

abdominal pain: Pain, cramping, or discomfort felt anywhere in the belly area.

acute kidney injury: A sudden drop in kidney function over hours or days, which is often reversible if the cause is treated.

Adverse Reactions: Unwanted or harmful effects that people experienced while taking a medicine, listed on its official label.

antidote: A treatment that reverses or counteracts the effects of a specific medicine or poison.

AUC: A measure of total drug exposure over time, showing how much medicine the blood is exposed to overall.

baseline: A person's starting condition, measured before treatment begins, used to see how much they change later on.

cardiac arrest: A sudden stop of the heart's pumping that cuts off blood flow to the body, which is a medical emergency.

clearance: How quickly the body removes a medicine from the blood, usually through the liver and kidneys.

Clostridioides difficile: A type of gut germ that can overgrow and cause severe, watery diarrhea, often after antibiotic use.

colitis: Swelling and irritation of the inner lining of the large intestine, or colon.

diarrhea: Loose, watery bowel movements that happen more often than normal.

Dosage and Administration: The label section explaining how much of a medicine to use and how to take or give it.

Drug Interactions: The label section listing other medicines, foods, or substances that can change how a medicine works or raise the chance of side effects.

flushing: Temporary redness and warmth of the skin, often on the face and neck, from widening of small blood vessels.

Full Prescribing Information: The complete, detailed label for a prescription medicine that follows the summary highlights.

Indications and Usage: The label section stating which medical conditions the FDA has officially approved the medicine to treat, prevent, or manage.

infusion: Slowly delivering fluid or medicine into a vein over a period of time, usually through a drip.

intravenous: Given directly into a vein through a needle or thin tube; often written as IV.

NDC: A unique number that identifies a specific medicine, its maker, strength, and package size.

Prescribing Information: The official, detailed document approved by the FDA that tells health professionals how to use a prescription medicine.

Stevens-Johnson syndrome: A rare, serious reaction causing painful blistering and peeling of the skin and the moist linings of the mouth, eyes, and other areas.

toxic epidermal necrolysis: A rare, life-threatening reaction in which large areas of the top layer of skin blister and peel away, like a severe burn.

trimester: One of the three roughly three-month stages that a pregnancy is divided into.

Warnings and Precautions: The label section describing serious risks to know about and safety steps to follow while using a medicine.

wheezing: A high-pitched whistling sound made while breathing, usually when the airways are narrowed.

🔬 Where this comes from

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄

FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Aug 19, 2026

🏭

Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Vancomycin.

📈

Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.

🚨

Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.

🧾 Clinical label set — FDA-filed SPL labels retained for Vancomycin after exact ingredient or ingredient-combination matching and applicable route/form matching

Clinical labels in scope: 57
NDC products indexed: 392
Distinct labelers/manufacturers represented: 65
Linked representative label ⓘ: Hikma Pharmaceuticals USA Inc.
Linked label effective: Aug 19, 2026
Composite sections available: 25
Linked SPL Set ID: 72e9c5e2-07cc-4a8b-ba64-b2e7619ea560
Linked SPL Document ID: 7bddeff1-1858-437c-b772-b063a7e7c6f8

Open the linked representative label on DailyMed ↗

How we combine label and product data

HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 57 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.

For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Hikma Pharmaceuticals USA Inc. is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.

This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.

Vancomycin

📖 Vancomycin: Patient Information Guide

Supplements & herbs that interact with Vancomycin

Nutrient depletion considerations

🩺 Pharmacist Counseling Corner

🧰 Keep exploring

💊 How Vancomycin comes

Injection

Capsule

Oral solution

📊 Vancomycin across the U.S. market

📈 How widely Vancomycin is used

🔍 Compare Vancomycin products

📈 What people report — real-world data (FDA FAERS)

🏛️ The road to your pharmacy

🚨 Recall history

RxNorm Concept Web — From Ingredient to Every Form and Strength

📦 Supply & shortage status

🏷️ Sold under these brand names

🏭 Manufacturers & labelers

RxNorm drug class

🔬 Where this comes from

How we combine label and product data

Vancomycin

📖 Vancomycin: Patient Information Guide

Supplements & herbs that interact with Vancomycin

Nutrient depletion considerations

🩺 Pharmacist Counseling Corner

🧰 Keep exploring

💊 How Vancomycin comes

📊 Vancomycin across the U.S. market

📈 How widely Vancomycin is used

🔍 Compare Vancomycin products

📈 What people report — real-world data (FDA FAERS)

🏛️ The road to your pharmacy

🚨 Recall history

🗺️ RxNorm Concept Web — From Ingredient to Every Form and Strength

📦 Supply & shortage status

🏷️ Sold under these brand names

🏭 Manufacturers & labelers

🏷️ RxNorm drug class

🔬 Where this comes from

How we combine label and product data

🔗 Related medications

RxNorm Concept Web — From Ingredient to Every Form and Strength

RxNorm drug class