Vancomycin Injection

Generic name: Pronounced as (van" koe mye' sin)

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 04/15/2016

Vancomycin injection is used alone or in combination with other medications to treat certain serious infections such as endocarditis (infection of the heart lining and valves), peritonitis (inflammation of the lining of the abdomen), and infections of the lungs, skin, blood, and bones. Vancomycin injection is in a class of medications called glycopeptide antibiotics. It works by killing bacteria that cause infections.

Antibiotics such as vancomycin injection will not work for colds, flu, or other viral infections. Taking or using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

Vancomycin injection comes as a powder to be added to fluid and injected intravenously (into a vein). It is usually infused (injected slowly) over a period of at least 60 minutes once every 6 or 12 hours, but may be given every 8 hours in newborn babies. The length of your treatment depends on the type of infection you have.

You may experience a reaction while you receive a dose of vancomycin injection, usually during your infusion or soon after your infusion has completed. Tell your doctor immediately if you experience any of these symptoms while you receive vancomycin injection: dizziness, wheezing, shortness of breath, itching, hives, flushing of the upper body, or muscle pain or spasm of the chest and back.

You may receive vancomycin injection in a hospital or you may use the medication at home. If you are using vancomycin injection at home, use it at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or other healthcare provider to explain any part you do not understand. Use vancomycin injection exactly as directed. Do not infuse it more quickly than directed. Do not use more or less of it or use it more often than prescribed by your doctor.

If you will be using vancomycin injection at home, your healthcare provider will show you how to infuse the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions. Ask your healthcare provider what to do if you have any problems infusing vancomycin injection.

You should begin feeling better during the first few days of your treatment with vancomycin injection. If your symptoms do not improve, or if they get worse, call your doctor.

Use vancomycin injection until you finish the prescription, even if you feel better. If you stop using vancomycin injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Vancomycin injection may also be given orally to treat colitis (inflammation of the intestine caused by certain bacteria) that may occur after antibiotic treatment.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before using vancomycin injection,

  • tell your doctor and pharmacist if you are allergic to vancomycin, any other medications, or any of the ingredients in vancomycin injection. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amikacin, amphotericin (Abelcet, Ambisome, Amphotec), bacitracin (Baciim); cisplatin, colistin, kanamycin, neomycin (Neo-Fradin), paromomycin, polymyxin B, streptomycin, and tobramycin. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you have or have ever had hearing problems or kidney disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using vancomycin injection, call your doctor.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are receiving vancomycin injection.

Unless your doctor tells you otherwise, continue your normal diet.

Infuse the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not infuse a double dose to make up for a missed one.

  • Vancomycin injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • pain, redness, or swelling at the injection site

    • fever

    • nausea

    • chills

  • Some side effects can be serious. If you experience any of these symptoms or those listed in the HOW section, call your doctor immediately or get emergency medical treatment:

    • severe diarrhea with watery or bloody stools (up to 2 months after your treatment)

    • stomach pain or cramps

    • rash

    • peeling or blistering of the skin

    • swelling of the eyes, face, throat, tongue, or lips

    • difficulty breathing or swallowing

    • hoarseness

    • hearing loss, roaring or ringing in the ears, or dizziness

  • Vancomycin injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to vancomycin injection.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Alendronate Alendronate The risk or severity of nephrotoxicity and hypocalcemia can be increased when Vancomycin is combined with Alendronic acid.
Cilostazol Cilostazol Cilostazol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Conjugated estrogens may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Fenofibrate Fenofibrate Fenofibrate may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Guanfacine Guanfacine Guanfacine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Magnesium Gluconate Magnesium Gluconate The risk or severity of neuromuscular blockade can be increased when Vancomycin is combined with Magnesium gluconate.
Magnesium Hydroxide Magnesium Hydroxide Magnesium hydroxide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Magnesium Oxide Magnesium Oxide The risk or severity of neuromuscular blockade can be increased when Vancomycin is combined with Magnesium oxide.
Mycophenolate Mycophenolate Mycophenolic acid may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Olsalazine Olsalazine Olsalazine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Potassium Potassium Vancomycin may decrease the excretion rate of Potassium cation which could result in a higher serum level.
Prednisone Prednisone Prednisone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ranitidine Ranitidine Ranitidine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Reserpine Reserpine Reserpine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Rizatriptan Rizatriptan Rizatriptan may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Sumatriptan Sumatriptan Sumatriptan may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tacrolimus Tacrolimus Tacrolimus may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tiludronate Tiludronate The risk or severity of nephrotoxicity and hypocalcemia can be increased when Vancomycin is combined with Etidronic acid.
Ampicillin Injection Ampicillin Injection Ampicillin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection Doxycycline may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Fluconazole Injection Fluconazole Injection Fluconazole may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Foscarnet Injection Foscarnet Injection The risk or severity of nephrotoxicity can be increased when Vancomycin is combined with Foscarnet.
Hydromorphone Injection Hydromorphone Injection Hydromorphone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Levofloxacin Injection Levofloxacin Injection Levofloxacin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Meperidine Injection Meperidine Injection Meperidine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Metoclopramide Injection Metoclopramide Injection Metoclopramide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pamidronate Injection Pamidronate Injection Pamidronic acid may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Altretamine Altretamine Amphetamine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cyclosporine Cyclosporine Cyclosporine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Torsemide Torsemide Torasemide may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
Meloxicam Meloxicam Meloxicam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Risedronate Risedronate The risk or severity of nephrotoxicity and hypocalcemia can be increased when Vancomycin is combined with Risedronic acid.
Sevelamer Sevelamer The therapeutic efficacy of Vancomycin can be decreased when used in combination with Sevelamer.
Temozolomide Temozolomide Temozolomide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Zaleplon Zaleplon Zaleplon may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Perindopril Perindopril Perindopril may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tenofovir Tenofovir Tenofovir may increase the nephrotoxic activities of Vancomycin.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Eplerenone Eplerenone Eplerenone may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
Zonisamide Zonisamide Zonisamide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Atomoxetine Atomoxetine Atomoxetine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Atazanavir Atazanavir Atazanavir may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Almotriptan Almotriptan Almotriptan may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Emtricitabine Emtricitabine Emtricitabine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Memantine Memantine Memantine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tadalafil Tadalafil Tadalafil may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Duloxetine Duloxetine Duloxetine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tinidazole Tinidazole Tinidazole may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cefditoren Cefditoren Cefdinir may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cyanocobalamin Injection Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Eszopiclone Eszopiclone Eszopiclone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ganciclovir Ganciclovir Ganciclovir may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ribavirin Ribavirin Ribavirin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Valganciclovir Valganciclovir Valganciclovir may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Zoledronic Acid Injection Zoledronic Acid Injection The risk or severity of nephrotoxicity and hypocalcemia can be increased when Vancomycin is combined with Zoledronic acid.
Adefovir Adefovir Adefovir may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine Amphetamine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ibandronate Ibandronate The risk or severity of nephrotoxicity and hypocalcemia can be increased when Vancomycin is combined with Ibandronate.
Ramelteon Ramelteon Ramelteon may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Fentanyl Fentanyl Fentanyl may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pregabalin Pregabalin Pregabalin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ranolazine Ranolazine Ranolazine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Rasagiline Rasagiline Rasagiline may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Sitagliptin Sitagliptin Sitagliptin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Varenicline Varenicline Varenicline may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Albuterol Albuterol Salbutamol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Paliperidone Paliperidone Paliperidone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Clofarabine Injection Clofarabine Injection Clofarabine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Lubiprostone Lubiprostone Lubiprostone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pemetrexed Injection Pemetrexed Injection Vancomycin may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Sorafenib Sorafenib Sorafenib may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Levocetirizine Levocetirizine Levocetirizine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pegaptanib Injection Pegaptanib Injection Pegaptanib may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Azacitidine Injection Azacitidine Injection Azacitidine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Lenalidomide Lenalidomide Lenalidomide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Budesonide Budesonide Budesonide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Desmopressin Desmopressin Desmopressin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Vancomycin is combined with Botulinum toxin type A.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Vancomycin is combined with Botulinum Toxin Type B.
Doripenem Injection Doripenem Injection Doripenem may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Arsenic Trioxide Injection Arsenic Trioxide Injection Arsenic trioxide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Desvenlafaxine Desvenlafaxine Desvenlafaxine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cevimeline Cevimeline Cevimeline may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Certolizumab Injection Certolizumab Injection Certolizumab pegol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Daptomycin Injection Daptomycin Injection Daptomycin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Methylnaltrexone Injection Methylnaltrexone Injection Methylnaltrexone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Midazolam Midazolam Midazolam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Dexrazoxane Injection Dexrazoxane Injection Dexrazoxane may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Milnacipran Milnacipran Milnacipran may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Plerixafor Injection Plerixafor Injection Plerixafor may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Fesoterodine Fesoterodine Fesoterodine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Prasugrel Prasugrel Prasugrel may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) Tolvaptan may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Vancomycin is combined with Botulinum toxin type A.
Pralatrexate Injection Pralatrexate Injection Pralatrexate may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection Palonosetron may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Saxagliptin Saxagliptin Saxagliptin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Telavancin Injection Telavancin Injection Telavancin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Topotecan Topotecan Topotecan may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Dalfampridine Dalfampridine Dalfampridine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Vancomycin is combined with Botulinum toxin type A.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Acetaminophen Injection Acetaminophen Injection Acetaminophen may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ipilimumab Injection Ipilimumab Injection Ipilimumab may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Terbutaline Injection Terbutaline Injection Terbutaline may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Roflumilast Roflumilast Roflumilast may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Rivaroxaban Rivaroxaban Rivaroxaban may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ruxolitinib Ruxolitinib Ruxolitinib may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Clobazam Clobazam Clobazam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Deferiprone Deferiprone Deferiprone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Naloxone Injection Naloxone Injection Naloxone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Fondaparinux Injection Fondaparinux Injection Fondaparinux may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Enzalutamide Enzalutamide Enzalutamide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Mirabegron Mirabegron Mirabegron may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Teduglutide Injection Teduglutide Injection Teduglutide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Alogliptin Alogliptin Alogliptin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pomalidomide Pomalidomide Pomalidomide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Canagliflozin Canagliflozin Canagliflozin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Methazolamide Methazolamide Methazolamide may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
Trametinib Trametinib Trametinib may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Levomilnacipran Levomilnacipran Levomilnacipran may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ertapenem Injection Ertapenem Injection Ertapenem may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tigecycline Injection Tigecycline Injection The risk or severity of neuromuscular blockade can be increased when Vancomycin is combined with Tigecycline.
Vortioxetine Vortioxetine Vortioxetine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ketorolac Injection Ketorolac Injection Ketorolac may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Sofosbuvir Sofosbuvir Sofosbuvir may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Dapagliflozin Dapagliflozin Dapagliflozin may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
Apremilast Apremilast Apremilast may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Droxidopa Droxidopa Droxidopa may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Testosterone Injection Testosterone Injection Testosterone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Edoxaban Edoxaban Edoxaban may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Methamphetamine Methamphetamine Metamfetamine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tasimelteon Tasimelteon Tasimelteon may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Haloperidol Injection Haloperidol Injection Haloperidol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Amiloride Amiloride Amiloride may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
Macitentan Macitentan Macitentan may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Penicillin G Procaine Injection Penicillin G Procaine Injection Procaine benzylpenicillin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ixazomib Ixazomib Ixazomib may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Lesinurad Lesinurad Lesinurad may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Brivaracetam Injection Brivaracetam Injection Brivaracetam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Furosemide Injection Furosemide Injection Furosemide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Lixisenatide Injection Lixisenatide Injection Lixisenatide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Doxepin (Insomnia) Doxepin (Insomnia) Doxepin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Deutetrabenazine Deutetrabenazine Deutetrabenazine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Valbenazine Valbenazine Valbenazine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Naldemedine Naldemedine Naldemedine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Benznidazole Benznidazole Benznidazole may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Delafloxacin Delafloxacin Delafloxacin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ertugliflozin Ertugliflozin Ertugliflozin may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
Apalutamide Apalutamide Apalutamide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Baricitinib Baricitinib Baricitinib may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Lofexidine Lofexidine Lofexidine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Plazomicin Injection Plazomicin Injection Vancomycin may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Stiripentol Stiripentol Stiripentol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Prucalopride Prucalopride Prucalopride may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Magnesium Citrate Magnesium Citrate The risk or severity of neuromuscular blockade can be increased when Vancomycin is combined with Magnesium citrate.
Acyclovir Ophthalmic Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Solriamfetol Solriamfetol Solriamfetol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pitolisant Pitolisant Pitolisant may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives Drospirenone may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
Viloxazine Viloxazine Viloxazine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tobramycin Injection Tobramycin Injection Tobramycin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Fenoprofen Fenoprofen Fenoprofen may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Indomethacin Indomethacin Indomethacin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Mefenamic Acid Mefenamic Acid Mefenamic acid may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Naproxen Naproxen Naproxen may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tolmetin Tolmetin Tolmetin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Sulindac Sulindac Sulindac may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Isotretinoin Isotretinoin Isotretinoin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Sucralfate Sucralfate Sucralfate may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Floxuridine Floxuridine Floxuridine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Metaxalone Metaxalone Metaxalone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Methotrexate Injection Methotrexate Injection Methotrexate may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Chlorpromazine Chlorpromazine Chlorpromazine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Diazepam Diazepam Diazepam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Oxazepam Oxazepam Oxazepam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Flurazepam Flurazepam Flurazepam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Clorazepate Clorazepate Clorazepic acid may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Lorazepam Lorazepam Lorazepam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Carmustine Carmustine Carmustine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Amantadine Amantadine Amantadine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Codeine Codeine Codeine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Phenelzine Phenelzine Phenelzine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tetracycline Tetracycline Tetracycline may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Minocycline Minocycline The risk or severity of neuromuscular blockade can be increased when Vancomycin is combined with Minocycline.
Demeclocycline Demeclocycline The risk or severity of neuromuscular blockade can be increased when Vancomycin is combined with Demeclocycline.
Bleomycin Bleomycin Bleomycin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Sulfadiazine Sulfadiazine Sulfadiazine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Methadone Methadone Methadone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Benztropine Benztropine Benzatropine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Colestipol Colestipol The therapeutic efficacy of Vancomycin can be decreased when used in combination with Colestipol.
Maprotiline Maprotiline Maprotiline may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ibuprofen Ibuprofen Ibuprofen may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Azathioprine Azathioprine Azathioprine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Methylphenidate Methylphenidate Methylphenidate may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Sulfasalazine Sulfasalazine Sulfasalazine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Phenazopyridine Phenazopyridine Vancomycin may decrease the excretion rate of Phenazopyridine which could result in a higher serum level.
Carbamazepine Carbamazepine Vancomycin may decrease the excretion rate of Carbamazepine which could result in a higher serum level.
Methyldopa Methyldopa Methyldopa may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Hydralazine Hydralazine Hydralazine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cimetidine Cimetidine Cimetidine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Gentamicin Injection Gentamicin Injection Gentamicin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Warfarin Warfarin Vancomycin may decrease the excretion rate of Warfarin which could result in a higher serum level.
Clonazepam Clonazepam Clonazepam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Promethazine Promethazine Promethazine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Meclofenamate Meclofenamate Meclofenamic acid may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Nitrofurantoin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Digoxin Digoxin Vancomycin may decrease the excretion rate of Digoxin which could result in a higher serum level.
Chloroquine Chloroquine Chloroquine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Quinine Quinine The risk or severity of neuromuscular blockade can be increased when Quinine is combined with Vancomycin.
Triamterene Triamterene Triamterene may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Lactulose Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Vancomycin.
Chlorothiazide Chlorothiazide Chlorothiazide may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
Chlorthalidone Chlorthalidone Chlorthalidone may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
Metolazone Metolazone Metolazone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Isosorbide Isosorbide Isosorbide may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
Clindamycin Injection Clindamycin Injection The risk or severity of neuromuscular blockade can be increased when Vancomycin is combined with Clindamycin.
Secobarbital Secobarbital Secobarbital may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Desipramine Desipramine Desipramine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Amitriptyline Amitriptyline Amitriptyline may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Imipramine Imipramine Imipramine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Probenecid Probenecid Probenecid may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Quinidine Quinidine Vancomycin may decrease the excretion rate of Quinidine which could result in a higher serum level.
Procainamide Procainamide Vancomycin may decrease the excretion rate of Procainamide which could result in a higher serum level.
Isoniazid Isoniazid Isoniazid may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pyrazinamide Pyrazinamide Pyrazinamide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Disopyramide Disopyramide Disopyramide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Butabarbital Butabarbital Butabarbital may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Liothyronine Liothyronine Liothyronine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Methimazole Methimazole Methimazole may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Chlorpropamide Chlorpropamide Chlorpropamide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tolbutamide Tolbutamide Tolbutamide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tolazamide Tolazamide Tolazamide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Baclofen Baclofen Vancomycin may decrease the excretion rate of Baclofen which could result in a higher serum level.
Ethambutol Ethambutol Ethambutol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Methyclothiazide Methyclothiazide Methyclothiazide may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
Hydrochlorothiazide Hydrochlorothiazide Hydrochlorothiazide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Dantrolene Dantrolene The risk or severity of neuromuscular blockade can be increased when Vancomycin is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone Chlorzoxazone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pyridoxine Pyridoxine Pyridoxine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Folic Acid Folic Acid Folic acid may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) Propranolol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Spironolactone Spironolactone Spironolactone may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Injection Amphotericin B Injection Amphotericin B may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Phytonadione Phytonadione Phylloquinone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Amikacin Injection Amikacin Injection Amikacin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Nadolol Nadolol Nadolol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cholestyramine Resin Cholestyramine Resin The therapeutic efficacy of Vancomycin can be decreased when used in combination with Cholestyramine.
Allopurinol Allopurinol Allopurinol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Flavoxate Flavoxate Flavoxate may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Colchicine Colchicine Colchicine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cefadroxil Cefadroxil Cefadroxil may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cephalexin Cephalexin Cephalexin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Dacarbazine Dacarbazine Dacarbazine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Acetazolamide Acetazolamide Acetazolamide may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pyrantel Pyrantel The therapeutic efficacy of Vancomycin can be increased when used in combination with Pyrantel.
Ethacrynic Acid Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Metoprolol Metoprolol Metoprolol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Aspirin Aspirin Acetylsalicylic acid may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Salsalate Salsalate Salsalate may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Alprazolam Alprazolam Alprazolam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Temazepam Temazepam Temazepam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Triazolam Triazolam Triazolam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Dicyclomine Dicyclomine Dicyclomine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Propantheline Propantheline Propantheline may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Trimethoprim Trimethoprim Trimethoprim may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Nifedipine Nifedipine Nifedipine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Timolol Timolol Timolol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Verapamil Verapamil Verapamil may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pindolol Pindolol Pindolol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cisplatin Injection Cisplatin Injection Vancomycin may decrease the excretion rate of Cisplatin which could result in a higher serum level.
Diflunisal Diflunisal Diflunisal may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Piroxicam Piroxicam Piroxicam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Bumetanide Bumetanide Bumetanide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Glipizide Glipizide Glipizide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Indapamide Indapamide Indapamide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Amoxicillin Amoxicillin Amoxicillin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Oxacillin Injection Oxacillin Injection Oxacillin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pentoxifylline Pentoxifylline Pentoxifylline may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pentamidine Injection Pentamidine Injection Pentamidine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ceftriaxone Injection Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Labetalol Labetalol Labetalol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Auranofin Auranofin Auranofin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection Leuprolide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Gemfibrozil Gemfibrozil Gemfibrozil may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ketoprofen Ketoprofen Ketoprofen may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cefotetan Injection Cefotetan Injection Cefotetan may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Flurbiprofen Flurbiprofen Flurbiprofen may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Aztreonam Injection Aztreonam Injection Aztreonam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Buspirone Buspirone Buspirone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ciprofloxacin Ciprofloxacin Ciprofloxacin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Mesalamine Mesalamine Mesalazine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Diclofenac Diclofenac Diclofenac may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Clozapine Clozapine Clozapine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Estazolam Estazolam Estazolam may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Didanosine Didanosine Didanosine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pentostatin Injection Pentostatin Injection Pentostatin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Etodolac Etodolac Etodolac may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Fosinopril Fosinopril Fosinopril may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Nabumetone Nabumetone Nabumetone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Lisinopril Lisinopril Lisinopril may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Oxaprozin Oxaprozin Oxaprozin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Bisoprolol Bisoprolol Bisoprolol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Isradipine Isradipine Isradipine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Venlafaxine Venlafaxine Venlafaxine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Fluvoxamine Fluvoxamine Fluvoxamine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Nefazodone Nefazodone Nefazodone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Lamotrigine Lamotrigine Lamotrigine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Valacyclovir Valacyclovir Valaciclovir may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tramadol Tramadol Tramadol may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Carboplatin Injection Carboplatin Injection Carboplatin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ifosfamide Injection Ifosfamide Injection Ifosfamide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Bupropion Bupropion Bupropion may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Ticlopidine Ticlopidine Ticlopidine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Metformin Metformin Metformin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Nisoldipine Nisoldipine Nisoldipine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Lamivudine Lamivudine Lamivudine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Acarbose Acarbose Acarbose may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Gemcitabine Injection Gemcitabine Injection Gemcitabine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Meropenem Injection Meropenem Injection Meropenem may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Clomipramine Clomipramine Clomipramine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Fosfomycin Fosfomycin Fosfomycin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Topiramate Topiramate Topiramate may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Pramipexole Pramipexole Pramipexole may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Nilutamide Nilutamide Nilutamide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Flutamide Flutamide Flutamide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tamsulosin Tamsulosin Tamsulosin may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Quetiapine Quetiapine Quetiapine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Cetirizine Cetirizine Cetirizine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tolcapone Tolcapone Tolcapone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Capecitabine Capecitabine Capecitabine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Abacavir Abacavir Abacavir may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Celecoxib Celecoxib Celecoxib may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Rosiglitazone Rosiglitazone Rosiglitazone may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Tolterodine Tolterodine Tolterodine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Oseltamivir Oseltamivir Oseltamivir may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Colesevelam Colesevelam The therapeutic efficacy of Vancomycin can be decreased when used in combination with Colesevelam.
Balsalazide Balsalazide Balsalazide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Nateglinide Nateglinide Nateglinide may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Rabeprazole Rabeprazole Rabeprazole may decrease the excretion rate of Vancomycin which could result in a higher serum level.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists