Free & pharmacist-reviewed

Drug & Supplement Interaction Checker

See whether your medications interact with vitamins, herbs, and supplements. Search by ingredient — like turmeric or vitamin K — or by supplement product, and get clear, evidence-based results in seconds.

214,000+
Supplements
300,000+
Interactions
100%
Free, no signup

Check an interaction

Add one medication & one supplement
+
Search by ingredient — e.g. turmeric, magnesium, or St. John’s Wort — not a brand or product name.
Reviewed by licensed pharmacists Sourced from Natural Medicines & NIH DSLD Free — no account needed
Popular checks: turmeric + warfarin vitamin K + warfarin St. John’s Wort + sertraline magnesium + levothyroxine ashwagandha + levothyroxine
Browse the directory. Explore every ingredient and product we track — 214,000+ supplements plus herbs, vitamins & minerals, A–Z or by name, brand, or barcode. Open directory
NEW 📸 Or just snap a photo of the label. Point your camera at the Supplement Facts panel — we read every active ingredient and check each one against your meds. Instantly. Scan your supplement
✨ Not sure where to start? Just ask. Type your question in plain English — “Can I take turmeric with warfarin?” — and our pharmacist AI answers with links to the right pages. Ask the AI
Skip the search — just ask

Ask HelloPharmacist AI

Anything about drug & supplement interactions. Ask about an ingredient, a product, or a specific drug-and-supplement combination, and get a plain-language answer with links to the right pages on our site.

Try:

AI answers are generated from our pharmacist-reviewed interaction data and may be incomplete. Always confirm with your pharmacist or doctor. How we use AI

Clear results

Color-coded by severity

Every interaction we find is rated and explained in plain language, with the evidence behind it.

Major

Clinically significant. Best to avoid the combination, or use only under close professional supervision.

Moderate

Be cautious. The combination may call for monitoring, timing changes, or a dose adjustment.

Minor

Limited clinical concern, but still worth being aware of and mentioning to your pharmacist.

Simple

How it works

Three steps — no sign-up, no jargon.

Step 1

Add your medication

Start typing any prescription or OTC drug name.

Step 2

Add a supplement ingredient

Search by ingredient — turmeric, magnesium, CoQ10.

Step 3

Get clear, sourced results

See severity, what to do, and the evidence behind it.

Natural Medicines database NIH Supplement Label Database Pharmacist-reviewed
Good to know

Common questions

The things people ask most about checking supplement interactions.

Who creates and reviews the interactions I see?
Most of our interaction content is provided by the Natural Medicines database and then reviewed by licensed HelloPharmacist pharmacists, who may add additional detail or clinical context from our team. So each interaction pairs an evidence-based source with a real pharmacist’s review — not opinion.
Where does your interaction data come from?
We build on Natural Medicines — one of the most respected, evidence-graded references for vitamins, herbs, and supplements — together with official product-label data from the NIH Dietary Supplement Label Database (DSLD). Our pharmacists curate and review what you see — see our editorial policy for how.
How do you rate the strength of an interaction?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the quality of the evidence behind it. We explain what the rating means and what to do about it, so you’re not left guessing.
Why search by ingredient instead of a brand or product?
Interactions happen at the ingredient level — it’s the turmeric or St. John’s Wort inside a product that interacts, not the brand on the label. Searching by ingredient catches every product that contains it, so nothing slips through.
Does this tool check drug-drug interactions too?
No — this checker focuses on drug ↔ supplement and herb interactions. To check two medications against each other, use our Drug Interactions tool.
Can medications affect my nutrient levels too?
Yes — some medications have been associated with lower levels of certain vitamins and minerals over time (like metformin and vitamin B12). Our Nutrient Depletion Checker shows the reported associations for your medications and what to discuss with your pharmacist.
Is this a substitute for medical advice?
No. This tool is for information only and may not capture every possible interaction. Always confirm with your pharmacist or doctor before starting, stopping, or changing any medication or supplement.

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Our pharmacists answer your medication & supplement questions — free.

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Explore everything

Browse the full directory

Four ways in — explore by medication (every supplement checked against your drug, ranked by severity), by ingredient (every vitamin, herb & mineral with interaction data), by product (214,000+ supplements by name, brand, or barcode), or by brand.

Medication directory Pick your drug to see every supplement & herb with a documented interaction — ranked by severity. Browse medications Ingredient directory Every vitamin, mineral, herb & botanical we track — each with pharmacist-reviewed drug-interaction data. Browse ingredients Product directory Look up any bottle by name, brand, or barcode to see exactly what’s inside and how it interacts with medications. Browse products Brand directory Browse every supplement brand we track and see each brand’s full product range in one place. Browse brands
Always growing

New in the checker

The latest supplement products added to our catalog — each one ready to check against your medications right now.

Refreshed ZBiotics Pre-Alcohol Probiotic Drink ZBiotics Pre-Alcohol Probiotic Drink by ZBiotics Refreshed Aug 30 1 ingredient Check this product → MINDBODYSKIN 2 Hormonal Acne Supplement (No 5-HTP) MINDBODYSKIN 2 Hormonal Acne Supplement (No 5-HTP) by CLEARSTEM Added Aug 3 10 ingredients Check this product → Rho Nutrition Liposomal DIM+ Liquid Rho Nutrition Liposomal DIM+ Liquid by Rho Nutrition Added Jul 29 2 ingredients Check this product → Peach Perfect Hormone Hero Women's Daily Multivitamin Peach Perfect Hormone Hero Women's Daily Multivitamin by Peach Perfect Added Jul 29 6 ingredients Check this product → DIM Supplement 300mg with Black Pepper DIM Supplement 300mg with Black Pepper by Deal Supplement Added Jul 29 2 ingredients Check this product → Refreshed Apple Cider Vinegar Gummies - 60 Gummies Apple Cider Vinegar Gummies - 60 Gummies by WEEM Refreshed Jul 27 5 ingredients Check this product → DIM SGS+: DIM, Hormone + Detox DIM SGS+: DIM, Hormone + Detox by Simlike Added Jul 27 3 ingredients Check this product → Grassfed Beef Liver 4500mg Desiccated Capsules Grassfed Beef Liver 4500mg Desiccated Capsules by Carlyle Added Jul 27 1 ingredient Check this product → Lymphatic Drainage Drops for Bloat Relief & De-Puff Lymphatic Drainage Drops for Bloat Relief & De-Puff by LYMPHORIA Added Jul 23 4 ingredients Check this product → DripDrop Hydration Packets - Juicy Variety Pack - Single Serve Electrolytes Powder Drink Mix - Grape, Fruit Punch, Strawberry Lemonade, Cherry DripDrop Hydration Packets - Juicy Variety Pack - Single Serve Electrolytes Powder Drink Mix - Grape, Fruit Punch, Strawberry Lemonade, Cherry by DripDrop Added Jul 22 5 ingredients Check this product →

Browse the full product directory →

Disclaimer: This drug-supplement interaction checker is provided for informational purposes only and should not be used as a substitute for the advice of a healthcare professional. The information contained in this tool is not intended to diagnose, treat, cure, or prevent any disease.

Additionally, this tool does not encompass all potential interactions. The interactions between supplements, their ingredients and medications can be complex and are not always fully understood. Always be sure to consult with your doctor before making changes to your medication regimen.