Whole Package Ingredients & Drug Interactions
by Heart & Soil
What is this page for?
First and foremost: checking Whole Package against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Whole Package is a dietary supplement by Heart & Soil with 6 active ingredients. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Liver. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Whole Package by Heart & Soil
Ask about any prescription or over-the-counter medication and we check it for interactions with Whole Package by Heart & Soil — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Whole Package by Heart & Soil
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Heart & Soil's Whole Package is a 6-ingredient product that's an animal-organ blend in capsule form. The active ingredients are liver extract, platelets, immune proteins, whole blood extract (which breaks down into its individual components), red blood cells, white blood cells, and testicle tissue.
These are meant to deliver a range of nutrients from beef organs — the product is sealed with bovine gelatin capsules.
Does it work?
Couldn't assess
The evidence on liver extract for chronic fatigue syndrome is limited — it's rated possibly ineffective. For hepatitis C, there isn't reliable evidence either way in the data we hold.
The effectiveness of the other ingredients in this product hasn't been established in our records.
How safe is it?
Well-documented data
Liver extract is generally well tolerated in food amounts, but it can deliver high levels of vitamin A and iron, and there are source-quality concerns since it comes from raw animal liver from slaughterhouses. High vitamin A is a problem in pregnancy — the safety data advises against use unless your doctor says otherwise.
There's also a theoretical concern about contamination from mad cow disease (BSE) if the liver comes from countries where it's been reported, though no human cases from liver extract have been documented. No adverse reactions to the product itself have been reported, but a thorough safety evaluation hasn't been done.
Talk with your doctor before using this product.
Meds to double-check
Minor interactions only
Check before taking this if you're on warfarin (a blood thinner) or iron supplements or medications. Liver extract may reduce warfarin's effectiveness or increase your iron levels, both of which need monitoring.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.
This is an organ-meat supplement for people interested in nose-to-tail nutrition. If you take warfarin or iron supplements, check with your pharmacist first — liver extract could affect how they work.
Pregnant people should avoid it unless their doctor approves. For anyone else, a conversation with your pharmacist about your full medication list is worth having.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Whole Package, straight from the product label.
| Brand | Heart & Soil |
|---|---|
| Barcode (UPC) | 850018088114 |
| Net contents | 180 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2022 |
| DSLD ID | 276357 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Whole Package by Heart & Soil, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Liver | 750 mg | -- |
| Platelets | 0 NP | -- |
| Immune Proteins | 0 NP | -- |
| Whole Blood Extract | 750 mg | -- |
| Red Blood Cells | 0 NP | -- |
| White Blood Cells | 0 NP | -- |
| Testicle | 1500 mg | -- |
Other ingredients: Bovine Gelatin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Reclaim your birthright to radical health. It breaks my heart to see how our families and our children struggle with fatigue, brain fog, mood issues, infertility, and autoimmunity. Is this the new normal that will become our future? Why have we forsaken the vitality that is our birthright and accepted this suffering as inescapable? I believe with all my soul that the solution is nose-to-tail nourishment. It starts with the soil and regenerative practices that heal the land, love, and nourish our animals so that we may be deeply nourished in turn. When we honor and consume animals nose-to-tail, we receive all of the nutrients needed to thrive, in the most bioavailable forms. This is my passion, my purpose, my entire heart & soul. Let me show you a brighter future. Visit us online at www.heartandsoil.co to start your journey today. Paul Saladino, M.D.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
3 g organs per serving
Whole Package 500 mg ea 180 capsules
Formulation
Regenerative Small batch 100% grass-fed 100% grass-finished
Suggested/Recommended/Usage/Directions
Suggested Use: 6 capsules daily or as directed by a healthcare professional
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Whole Package by Heart & Soil label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Whole Package by Heart & Soil
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size6 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Liver
Interacts with3 drugs
Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...
Liver monograph & interactionsWhole Blood Extract
- › Platelets
- › Immune Proteins
- › Red Blood Cells
- › White Blood Cells
Testicle
Other (inactive) ingredients: Bovine Gelatin. These complete the product’s ingredient list but are not active constituents.
Whole Package by Heart & Soil Drug Interactions
HelloPharmacist Interaction Report
Heart & Soil's Whole Package contains one ingredient we've checked for interactions: liver extract.
It shows minor interactions with two drug types.
Read the full breakdown — every affected drug type, severity by severity
Liver extract contains small amounts of vitamin K, which can theoretically reduce how well warfarin (a blood thinner) works and lower your INR (a measure of blood clotting). This hasn't been directly studied in humans, but if you start, stop, or significantly change how much liver extract you're taking, it's worth discussing with your doctor or pharmacist.
Liver extract also contains heme iron. If you're already taking iron supplements or iron-containing medications, adding this product could push your total iron intake higher, raising the risk of stomach upset or iron buildup in your body — especially at high doses, with long-term use, or if you have a condition like hemochromatosis (iron overload disease).
We could not check several other ingredients in this product: Platelets, Immune Proteins, Red Blood Cells, White Blood Cells, and Testicle. Altogether, these interactions span 3 individual medications.
Use the medication checker on this page to verify your specific drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Whole Package?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Whole Package interact with 3 drugs. Click any drug to see the details.
1 of the 6 ingredients in Whole Package interact with drugs. Each result below shows which ingredient is responsible. Liver
Ferrous SulfateFeosol
How Ferrous Sulfate interacts with Whole Package — through 1 ingredient. Tap an ingredient for the detail:
LiverIron Minor
Interaction Summary
Liver extract can contain heme iron.
Read the full Liver + Ferrous Sulfate interactionWarfarinWarfarin
How Warfarin interacts with Whole Package — through 1 ingredient. Tap an ingredient for the detail:
LiverWarfarin (coumadin) Minor
Interaction Summary
Liver extract products may contain small and variable amounts of vitamin K.
Read the full Liver + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Whole Package — through 1 ingredient. Tap an ingredient for the detail:
LiverWarfarin (coumadin) Minor
Interaction Summary
Liver extract products may contain small and variable amounts of vitamin K.
Read the full Liver + Warfarin Sodium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Whole Package with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Liver
Iron
Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.
Warfarin (Coumadin)
Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.
Brand information
Manufacturer and brand details for Whole Package, from the product label.
Heart & Soil
See all Heart & Soil products- Name
- Heart & Soil, LLC.
- City
- Austin
- State
- TX
- ZipCode
- 78746
- Web Address
- www.heartandsoil.co
Whole Package by Heart & Soil: Common Questions
Does Whole Package by Heart & Soil interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What is this supposed to do?
Has anyone had bad reactions to it?
Is it safe if I have iron overload (hemochromatosis)?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Whole Package is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Whole Package’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Whole Package's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Liver Extract 4 references
- Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
- Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
- Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
- Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC