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⚠️ Current Drug Shortages

The FDA drug-shortage list in one searchable place. See what's in shortage, why, and which NDCs are affected — open any drug for the full detail. Resolved shortages are kept on file too.

233 drugs in shortage Refreshed Oct 6, 2026
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Oct 6, 2026 at 4:29 PM ET · yesterday

Ask about a drug shortage in plain English

Type a brand or generic, or ask a plain-English question — like “Is amoxicillin on backorder?” — and get a clear answer from the FDA drug-shortage list.

Where does this data come from?
Official FDA drug-shortage data (via openFDA), with drug names matched through the FDA NDC Directory. This data shows national, manufacturer-reported supply problems; local supply may differ.

Key stats

1,571
Currently in shortage
233
Distinct drugs
992
Updated in 30 days
1,571
With NDC match
19
Resolved on file
1,590
Records tracked

Biggest shortage impact right now Why?

High supply-risk drugs, ranked by how many patients rely on them (Medicaid prescriptions/yr).

  1. 1 Semaglutide Tablet (Rybelsus) High risk ~193,225 Rx/yr
  2. 2 Insulin Lispro Protamine and Insulin Lispro... High risk ~21,036 Rx/yr
  3. 3 Desmopressin Acetate Spray (Ddavp) High risk ~12,192 Rx/yr
  4. 4 Chlorothiazide Oral Suspension (Diuril) High risk ~7,744 Rx/yr
  5. 5 Lasmiditan Succinate Tablet (Reyvow) High risk ~5,486 Rx/yr

Utilization shown is Medicaid only (CMS State Drug Utilization Data). It has reporting gaps and under-represents drugs used mainly outside Medicaid — treat it as a relative signal, not total U.S. use.

What changed

Between the FDA refresh on Oct 5, 2026 and Oct 6, 2026.

233 active · Oct 6
1 newly added to shortage
0 resolved or cleared

Compared against our previously saved copy of the FDA list. “Resolved or cleared” means the FDA no longer lists it as a current shortage.

Newly reported shortages per month

3 newly reported · Oct 2026
Oct 2024 460 reported across 19 months Oct 2026

The shortage landscape — tap a tile to filter the list below

By Therapeutic Category
By Reason for Shortage
All records by status
Current 1,141
To Be Discontinued 430
Resolved 19

Shortage insights — tap to expand

Most-used drugs in shortageby Medicaid Rx/yr, where we have data

Utilization shown is Medicaid only (CMS State Drug Utilization Data). It has reporting gaps and under-represents drugs used mainly outside Medicaid — treat it as a relative signal, not total U.S. use. Counts are annual prescriptions across each drug’s matched NDCs — a proxy for how many patients a shortage touches.

Longest-running active shortageshow long each has dragged on

Shortage list — 238 drugs, active first · newest shortages first

Fluocinonide Ointment View full page → To Be Discontinued 🆕 New this refresh ⚠ Supply risk: Low ✓ 3 other companies list it 5 days 3 NDCs Dermatology First posted Oct 2, 2026 Updated Oct 2, 2026

Teva Pharmaceuticals has told the FDA it is discontinuing its fluocinonide ointment products — a company stopping its own product, not a nationwide shortage. 3 other companies still list the same medicine without a shortage report.

Supply risk: Low · 1/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 3 other companies listing it Medicaid use (2026): ~12,294 Rx

Reporting: Teva Pharmaceuticals USA, Inc.

Ivermectin Tablet (STROMECTOL) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 5 other companies list it 8 days 1 NDC Anti-Infective First posted Sep 29, 2026 Updated Sep 29, 2026

Merck Sharp & Dohme is stopping its ivermectin 3 mg tablets, with the change taking effect October 31, 2026. Other manufacturers — including Edenbridge Pharmaceuticals, A-S Medication Solutions, and NuCare Pharmaceuticals — still list ivermectin 3 mg tablets, including the brand Stromectol, as available sources.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 5 other companies listing it Medicaid use (2026): ~39 Rx

Reporting: Merck Sharp & Dohme LLC

Rivaroxaban Powder for Suspension (Xarelto) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 1 other company lists it 19 days 1 NDC Hematology First posted Sep 18, 2026 Updated Sep 18, 2026

Janssen Pharmaceuticals is stopping Xarelto (rivaroxaban) for suspension, and this change may be permanent. The 155 mg suspension is still listed by Ascend Laboratories as a source not reporting a shortage.

Supply risk: Low · 2/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 1 other company listing it Medicaid use (2026): ~5,092 Rx

Reporting: Janssen Pharmaceuticals

Rivastigmine Extended-Release Film View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 7 other companies list it 19 days 1 NDC Neurology First posted Sep 18, 2026 Updated Sep 18, 2026

Viatris is permanently stopping its rivastigmine extended-release film patch. The same medicine — including Exelon (rivastigmine) patches — is still listed as available from other manufacturers that have not reported a shortage.

Supply risk: Low · 1/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 7 other companies listing it Medicaid use (2026): ~67 Rx

Reporting: Mylan Pharmaceuticals Inc., a Viatris Company

Melphalan Hydrochloride Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 9 other companies list it 21 days 1 NDC Oncology First posted Sep 16, 2026 Updated Sep 16, 2026

Fresenius Kabi is permanently stopping production of Melphalan Hydrochloride Injection. The same medicine is still listed by other makers, including Heritage Pharmaceuticals, Sagent, Dr. Reddy's, and BPI Labs.

Supply risk: Low · 0/5 risk factors 0/1 reporting maker with supply 9 other companies listing it

Reporting: Fresenius Kabi USA, LLC

Micafungin Sodium Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 8 other companies list it 26 days 2 NDCs Anti-Infective First posted Sep 11, 2026 Updated Sep 11, 2026

Par Health is permanently stopping its micafungin sodium injection (20 mg/mL and 10 mg/mL vials) due to a business decision. Other makers — including Hikma, Sagent, Hisun, and Fresenius Kabi — still list micafungin injection in 50 mg and 100 mg strengths.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 8 other companies listing it Medicaid use (2025): ~86 Rx

Reporting: Par Health, USA LLC

DELFLEX (Dextrose Monohydrate, Sodium Chloride, S...) View full page → To Be Discontinued ⚠ Supply risk: High 27 days 1 NDC Renal First posted Sep 10, 2026 Updated Sep 10, 2026

Fresenius Medical Care is permanently stopping production of DELFLEX (dextrose monohydrate, sodium chloride, sodium lactate, calcium chloride, and magnesium chloride solution). No other manufacturers are currently listed as a source for this medicine.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply

Reporting: Fresenius Medical Care North America

RECARBRIO (Imipenem Anhydrous, Cilastatin, and Rele...) View full page → To Be Discontinued ⚠ Supply risk: High 28 days 1 NDC Anti-Infective First posted Sep 9, 2026 Updated Sep 9, 2026

Merck Sharp & Dohme is stopping RECARBRIO (imipenem/cilastatin/relebactam) injection, and the change is expected to be permanent. No other manufacturer makes this medicine, so all strengths will be unavailable once the discontinuation takes effect.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply Medicaid use (2026): ~131 Rx

Reporting: Merck Sharp & Dohme LLC

Glycerol Phenylbutyrate Oral Liquid (RAVICTI) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 6 other companies list it 36 days 2 NDCs Inborn Errors First posted Sep 1, 2026 Updated Sep 1, 2026

Amgen is permanently stopping its glycerol phenylbutyrate oral liquid (1.1 g/mL), and this change may be permanent. Other makers — including Teva Pharmaceuticals, Camber Pharmaceuticals, Par Health USA, and Aurobindo Pharma — still list the same medicine at the same strength.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 6 other companies listing it Medicaid use (2026): ~3,207 Rx

Reporting: Amgen Inc.

Insulin Glargine-aglr Injection (Rezvoglar) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 1 other company lists it 36 days 1 NDC Endocrinology/Metabolism First posted Sep 1, 2026 Updated Sep 1, 2026

Eli Lilly is stopping Rezvoglar (insulin glargine-aglr) injection, with distribution expected to end in June 2027. The 100 units/mL KwikPen is still listed as available from at least one other supplier.

Supply risk: Low · 2/5 risk factors 1/1 strength / size still listed 0/1 reporting maker with supply 1 other company listing it Medicaid use (2026): ~35,201 Rx

Reporting: Eli Lilly and Co.

Insulin Lispro Protamine and Insulin Lispro Injection (Humalog Mix 75/25) View full page → To Be Discontinued ⚠ Supply risk: High 36 days 1 NDC Endocrinology/Metabolism First posted Sep 1, 2026 Updated Sep 1, 2026

Eli Lilly is stopping Humalog Mix 75/25 (insulin lispro protamine and insulin lispro) permanently. No other manufacturer currently lists this medicine as available.

Supply risk: High · 5/5 risk factors 0/1 strength / size still listed 0/1 reporting maker with supply Medicaid use (2026): ~21,036 Rx

Reporting: Eli Lilly and Co.

Medroxyprogesterone Acetate Tablet (PROVERA) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 8 other companies list it 37 days 2 NDCs Urology First posted Aug 31, 2026 Updated Aug 31, 2026

Pfizer is permanently stopping production of Provera (medroxyprogesterone acetate) tablets, with withdrawal from sale expected by late 2026. Other manufacturers still list this medicine in 2.5 mg, 5 mg, and 10 mg strengths.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 8 other companies listing it

Reporting: Pfizer Inc.

Metoprolol Succinate Extended-Release Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 28 other companies list it 37 days 7 NDCs Cardiovascular First posted Aug 31, 2026 Updated Aug 31, 2026

Teva is permanently stopping its metoprolol succinate extended-release tablets — all strengths (25 mg, 50 mg, 100 mg, and 200 mg) are affected. Other manufacturers, including Major Pharmaceuticals and Camber Pharmaceuticals, still list the 25 mg, 50 mg, and 100 mg strengths as available.

Supply risk: Low · 0/5 risk factors 4/4 strengths still listed 0/1 reporting maker with supply 28 other companies listing it Medicaid use (2026): ~286,383 Rx

Reporting: Teva Pharmaceuticals USA, Inc.

Palovarotene Capsule (SOHONOS) View full page → To Be Discontinued ⚠ Supply risk: High 37 days 1 NDC Musculoskeletal First posted Aug 31, 2026 Updated Aug 31, 2026

Ipsen is permanently stopping production of Sohonos (palovarotene) capsules. No other manufacturer makes this medicine, so no listed source exists for any strength.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply

Reporting: Ipsen Biopharmaceuticals, Inc.

Cardioplegic Solution (Potassium Chloride, Sodium Chloride, Cal...) View full page → To Be Discontinued ⚠ Supply risk: High ✓ 1 other company lists it 37 days 1 NDC Cardiovascular First posted Aug 31, 2026 Updated Aug 31, 2026

Fresenius Kabi is stopping production of this potassium chloride/sodium chloride/calcium chloride/magnesium chloride injection solution, and the change may be permanent. Plegisol (potassium chloride, sodium chloride, calcium chloride injection solution) from Hospira is listed as an available option from a manufacturer not reporting a shortage.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 1 other company listing it

Reporting: Fresenius Kabi USA, LLC

Pentostatin Injection (Nipent) View full page → Current ⚠ Supply risk: High 41 days 1 NDC Oncology First posted Aug 27, 2026 Updated Aug 27, 2026

Nipent (pentostatin) injection is currently unavailable due to manufacturing delays at Pfizer, with no supply expected until mid-2027 at the earliest. No other manufacturers of this medicine are listed as an alternative source right now.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 100% of NDCs unavailable

Why: Other

Reporting: Hospira, Inc., a Pfizer Company

Mesalamine Extended-Release Capsule (Pentasa) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 12 other companies list it 43 days 3 NDCs 2 companies reporting Gastroenterology First posted Aug 25, 2026 Updated Sep 16, 2026

Mylan is permanently stopping its mesalamine extended-release capsules, and Takeda plans to stop supplying its version by end of 2027. Other makers — including Teva and Upsher-Smith — have not reported a shortage and still list mesalamine extended-release capsules as available.

Supply risk: Low · 1/5 risk factors 2/3 strengths still listed 0/2 reporting makers with supply 12 other companies listing it Medicaid use (2026): ~15,688 Rx

Reporting: Mylan Pharmaceuticals Inc., a Viatris Company, Takeda Pharmaceuticals USA Inc.

Disopyramide Phosphate Extended-Release Capsule (Norpace CR) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 3 other companies list it 44 days 2 NDCs Cardiovascular First posted Aug 24, 2026 Updated Aug 24, 2026

Pfizer is stopping production of Norpace CR (disopyramide phosphate) extended-release capsules, and this change may be permanent. Immediate-release disopyramide capsules in 100 mg and 150 mg are still listed by other manufacturers who have not reported a shortage.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 3 other companies listing it

Reporting: Pfizer Inc.

Fulvestrant Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 16 other companies list it 54 days 1 NDC Oncology First posted Aug 14, 2026 Updated Aug 14, 2026

Fresenius Kabi is permanently stopping production of fulvestrant injection (250 mg/5 mL). The same medicine — including Faslodex (fulvestrant) — is still listed as available from other manufacturers not reporting a shortage.

Supply risk: Low · 1/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 16 other companies listing it Medicaid use (2026): ~81 Rx

Reporting: Fresenius Kabi USA, LLC

Diclofenac Sodium Delayed-Release Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 25 other companies list it 55 days 6 NDCs Musculoskeletal, Rheumatology First posted Aug 13, 2026 Updated Aug 13, 2026

Teva is permanently stopping its diclofenac sodium delayed-release tablets. Other makers — including Rising Pharma, AvKARE, Edenbridge, and PD-Rx — still list this medicine in 25 mg, 50 mg, and 75 mg strengths, so supply may be available from other sources.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 25 other companies listing it Medicaid use (2026): ~2,868 Rx

Reporting: Teva Pharmaceuticals USA, Inc.

Plenvu (Polyethylene Glycol 3350, Sodium Ascorba...) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 2 other companies list it 55 days 1 NDC Gastroenterology First posted Aug 13, 2026 Updated Aug 13, 2026

Salix Pharmaceuticals is permanently stopping its version of this bowel-prep solution. The same medicine is still listed by other makers, including as MoviPrep and Plenvu.

Supply risk: Low · 0/5 risk factors 0/1 reporting maker with supply 2 other companies listing it Medicaid use (2025): ~5,485 Rx

Reporting: Salix Pharmaceuticals, a division of Bausch Health US, LLC

Glyburide Tablet (Diabeta) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 9 other companies list it 58 days 4 NDCs Endocrinology/Metabolism First posted Aug 10, 2026 Updated Aug 10, 2026

Sanofi-Aventis is permanently discontinuing its glyburide tablets. Other manufacturers, including Teva and Heritage Pharmaceuticals, still list glyburide in all three strengths (1.25 mg, 2.5 mg, and 5 mg) as available.

Supply risk: Low · 0/5 risk factors 3/3 strengths still listed 0/1 reporting maker with supply 9 other companies listing it Medicaid use (2026): ~10,584 Rx

Reporting: Sanofi-Aventis U.S. LLC

DIANEAL PD-2 with Dextrose (Calcium Chloride; Dextrose; Magnesium Ch...) View full page → To Be Discontinued ⚠ Supply risk: High 65 days 18 NDCs Renal First posted Aug 3, 2026 Updated Aug 3, 2026

Vantive US Healthcare LLC is stopping production of this intraperitoneal dialysis solution, and the change may be permanent. Some Dianeal formulations from Vantive are still listed as available, including Dianeal Low Calcium and Dianeal PD-2 with Dextrose in several strengths.

Supply risk: High · 5/5 risk factors 0/6 strengths still listed 0/1 reporting maker with supply

Reporting: Vantive US Healthcare LLC

Doxycycline Hyclate Delayed-Release Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 29 other companies list it 69 days 2 NDCs Anti-Infective First posted Jul 30, 2026 Updated Jul 30, 2026

Teva is permanently stopping its doxycycline hyclate delayed-release tablet. Delayed-release versions at 75 mg and 100 mg are still listed by other manufacturers not reporting a shortage.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 29 other companies listing it Medicaid use (2026): ~44 Rx

Reporting: Teva Pharmaceuticals USA, Inc.

Glycopyrrolate Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 16 other companies list it 69 days 4 NDCs Anesthesia First posted Jul 30, 2026 Updated Jul 30, 2026

Fresenius Kabi is permanently stopping production of glycopyrrolate injection. Other makers — including Hikma, American Regent, Sandoz, and Accord — still list glycopyrrolate injection in multiple strengths without reporting a shortage.

Supply risk: Low · 1/5 risk factors 1/4 strengths still listed 0/1 reporting maker with supply 16 other companies listing it Medicaid use (2026): ~1,392 Rx

Reporting: Fresenius Kabi USA, LLC

Fluticasone Propionate and Salmeterol Xinafoate Inhaler (Advair HFA) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 2 other companies list it 72 days 3 NDCs Pulmonary/Allergy First posted Jul 27, 2026 Updated Jul 27, 2026

GlaxoSmithKline is stopping its Advair HFA (fluticasone/salmeterol) inhaler, with distribution ending around December 31, 2026. Other manufacturers still list Advair HFA and fluticasone/salmeterol HFA inhalers as available.

Supply risk: Low · 0/5 risk factors 3/3 strengths still listed 0/1 reporting maker with supply 2 other companies listing it Medicaid use (2026): ~527 Rx

Reporting: GlaxoSmithKline

Lopinavir and Ritonavir Oral Solution (Kaletra) View full page → To Be Discontinued ⚠ Supply risk: High 75 days 1 NDC Antiviral First posted Jul 24, 2026 Updated Jul 24, 2026

Kaletra (lopinavir and ritonavir) oral solution is being permanently discontinued by AbbVie. No other makers list this medicine as available right now.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply Medicaid use (2026): ~23 Rx

Reporting: AbbVie Inc.

Lopinavir and Ritonavir Tablet (Kaletra) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 2 other companies list it 75 days 4 NDCs Antiviral First posted Jul 24, 2026 Updated Jul 24, 2026

AbbVie is stopping production of Kaletra (lopinavir/ritonavir) tablets, and this change may be permanent. Generic versions of the same medicine are still listed by other manufacturers.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 2 other companies listing it Medicaid use (2026): ~25 Rx

Reporting: AbbVie Inc.

Ritonavir Oral Powder (Norvir) View full page → To Be Discontinued ⚠ Supply risk: High 75 days 1 NDC Antiviral First posted Jul 24, 2026 Updated Jul 24, 2026

Norvir (ritonavir) oral powder is being discontinued by AbbVie, and this change may be permanent. No other maker lists this powder form as available right now.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply Medicaid use (2026): ~17 Rx

Reporting: AbbVie Inc.

Ritonavir Tablet (Norvir) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 5 other companies list it 75 days 1 NDC Antiviral First posted Jul 24, 2026 Updated Jul 24, 2026

AbbVie is stopping production of Norvir (ritonavir) tablets, and this change may be permanent. The 100 mg tablet is still listed by other manufacturers that have not reported a shortage.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 5 other companies listing it Medicaid use (2026): ~1,923 Rx

Reporting: AbbVie Inc.

Aspirin Suppository View full page → To Be Discontinued ⚠ Supply risk: High 76 days 1 NDC Analgesia/Addiction, Cardiovascular First posted Jul 23, 2026 Updated Jul 23, 2026

Padagis is permanently stopping production of aspirin suppositories (300 mg), and no other manufacturer currently lists this product. This strength has no known available source at this time.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply

Reporting: Padagis US LLC

Belladonna and Opium Suppository View full page → To Be Discontinued ⚠ Supply risk: High 76 days 4 NDCs Analgesia/Addiction First posted Jul 23, 2026 Updated Jul 23, 2026

Padagis is permanently stopping production of Belladonna and Opium suppositories. No other manufacturer is listed as a source for any strength of this medicine right now.

Supply risk: High · 5/5 risk factors 0/2 strengths still listed 0/1 reporting maker with supply Medicaid use (2025): ~11 Rx

Reporting: Padagis US LLC

Bendamustine Hydrochloride Injection (Treanda) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 10 other companies list it 76 days 1 NDC Oncology First posted Jul 23, 2026 Updated Jul 23, 2026

Teva is permanently stopping Treanda (bendamustine hydrochloride injection). Other makers, including Baxter Healthcare, Accord Healthcare, Azurity Pharmaceuticals, and Eagle Pharmaceuticals, still list bendamustine hydrochloride injection in multiple strengths and forms.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 10 other companies listing it Medicaid use (2025): ~28 Rx

Reporting: Cephalon, LLC (a wholly owned subsidiary of Teva Pharmaceutical Industries, Ltd.)

Hydrocortisone Acetate Suppository View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 16 other companies list it 76 days 2 NDCs Analgesia/Addiction, Other First posted Jul 23, 2026 Updated Jul 23, 2026

Padagis is permanently stopping production of hydrocortisone acetate suppositories. Other manufacturers — including makers of Anucort-HC (hydrocortisone acetate) — still list both the 25 mg and 30 mg suppositories as available.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 16 other companies listing it

Reporting: Padagis US LLC

Hydromorphone Hydrochloride Suppository View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 1 other company lists it 76 days 1 NDC Analgesia/Addiction First posted Jul 23, 2026 Updated Jul 23, 2026

Padagis is stopping production of hydromorphone hydrochloride suppositories, and this change may be permanent. The 3 mg suppository is still listed by Bryant Ranch Prepack, which has not reported a shortage.

Supply risk: Low · 2/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 1 other company listing it Medicaid use (2026): ~35 Rx

Reporting: Padagis US LLC

Morphine Sulfate Suppository View full page → To Be Discontinued ⚠ Supply risk: High 76 days 4 NDCs Analgesia/Addiction First posted Jul 23, 2026 Updated Jul 23, 2026

Padagis is permanently stopping production of morphine sulfate suppositories, and no other manufacturer is currently listed as a source for any strength. This medicine is not available from any reported maker right now.

Supply risk: High · 5/5 risk factors 0/4 strengths still listed 0/1 reporting maker with supply

Reporting: Padagis US LLC

Podophyllum Resin Topical Tincture (Podocon 25, Topical Tincture) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 1 other company lists it 76 days 1 NDC Dermatology First posted Jul 23, 2026 Updated Jul 23, 2026

Padagis is stopping production of Podophyllum Resin Topical Tincture, and this change may be permanent. Podocon-25 (podophyllum resin) 1 mg/4 mL tincture is still listed as available from Bryant Ranch Prepack.

Supply risk: Low · 2/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 1 other company listing it

Reporting: Padagis US LLC

Succinylcholine Chloride Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 11 other companies list it 76 days 1 NDC Anesthesia First posted Jul 23, 2026 Updated Jul 23, 2026

Fresenius Kabi is stopping production of Succinylcholine Chloride Injection 20 mg/mL, and this change may be permanent. The same medicine at the same strength is still listed by other manufacturers, including Quelicin (succinylcholine chloride) from Hospira.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 11 other companies listing it Medicaid use (2026): ~53 Rx

Reporting: Fresenius Kabi USA, LLC

Tobramycin Sulfate Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 3 other companies list it 82 days 1 NDC Anti-Infective First posted Jul 17, 2026 Updated Jul 17, 2026

Pfizer (Hospira) is permanently stopping its tobramycin sulfate injection. The same medicine at both 40 mg/mL and 10 mg/mL strengths is still listed as available from other manufacturers, including Baxter Healthcare, Fresenius Kabi, and Mylan Institutional.

Supply risk: Low · 1/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 3 other companies listing it Medicaid use (2026): ~1,131 Rx

Reporting: Hospira, Inc., a Pfizer Company

Travoprost Ophthalmic Solution View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 9 other companies list it 92 days 2 NDCs Ophthalmology First posted Jul 7, 2026 Updated Jul 7, 2026

Mylan is permanently stopping its travoprost ophthalmic solution, affecting both the 2.5 mL and 5 mL sizes. Other makers — including Novartis, Sagent, Micro Labs, and Golden State Medical Supply — still list travoprost eye drops (including Travatan Z), so supply may be available from other sources.

Supply risk: Low · 1/5 risk factors 0/2 strengths still listed 0/1 reporting maker with supply 9 other companies listing it Medicaid use (2026): ~578 Rx

Reporting: Mylan Pharmaceuticals Inc., a Viatris Company

Desflurane for Inhalation View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 1 other company lists it 97 days 1 NDC Anesthesia First posted Jul 2, 2026 Updated Jul 2, 2026

Jiangsu Hengrui is permanently stopping production of desflurane liquid for inhalation. Suprane (desflurane) 240 mL is still listed as available from Baxter Healthcare.

Supply risk: Low · 2/5 risk factors 1/1 size still listed 0/1 reporting maker with supply 1 other company listing it Medicaid use (2026): ~23 Rx

Reporting: Jiangsu Hengrui Pharmaceuticals Co. (US Agent eVenus Pharmaceutical Laboratories, Inc.)

Daptomycin Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 19 other companies list it 99 days 2 NDCs Anti-Infective First posted Jun 30, 2026 Updated Jun 30, 2026

Jiangsu Hengrui is permanently stopping its daptomycin injection. Other makers — including Hikma, Hospira, and Accord — still list daptomycin in 350 mg and 500 mg strengths and have not reported a shortage.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 19 other companies listing it Medicaid use (2026): ~87 Rx

Reporting: Jiangsu Hengrui Pharmaceuticals Co. (US Agent eVenus Pharmaceutical Laboratories, Inc.)

Gadobutrol Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 3 other companies list it 99 days 4 NDCs Medical Imaging First posted Jun 30, 2026 Updated Jun 30, 2026

Jiangsu Hengrui is discontinuing its gadobutrol injection single-dose vials, and this change may be permanent. The same medicine at 604.72 mg/mL — including Gadavist (gadobutrol) — is still listed by other manufacturers not reporting a shortage.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 3 other companies listing it Medicaid use (2025): ~9,697 Rx

Reporting: Jiangsu Hengrui Pharmaceuticals Co., Ltd.

Emtricitabine Capsule (Emtriva) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 1 other company lists it 112 days 1 NDC Anti-Infective First posted Jun 17, 2026 Updated Jun 17, 2026

Gilead Sciences is stopping Emtriva (emtricitabine) capsules, and this change may be permanent. Supply from Gilead is expected to last until March 2027; a 200 mg capsule is also listed by Cipla USA as a source not currently reporting a shortage.

Supply risk: Low · 2/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 1 other company listing it Medicaid use (2025): ~218 Rx

Reporting: Gilead Sciences, Inc.

Emtricitabine Oral Solution (Emtriva) View full page → To Be Discontinued ⚠ Supply risk: High 112 days 1 NDC Anti-Infective First posted Jun 17, 2026 Updated Jun 17, 2026

Gilead Sciences is stopping its emtricitabine oral solution (10 mg/mL), and this change is expected to be permanent. No other manufacturers of this liquid form are currently listed, so supply will not be available after March 2027.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply

Reporting: Gilead Sciences, Inc.

Donepezil Hydrochloride; Memantine Hydrochloride Extended-Release Capsule View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 5 other companies list it 114 days 2 NDCs Neurology First posted Jun 15, 2026 Updated Jun 15, 2026

Amneal Pharmaceuticals is permanently stopping its generic donepezil/memantine extended-release capsules. Namzaric (donepezil/memantine) capsules in multiple strengths are still listed as available from other manufacturers not reporting a shortage.

Supply risk: Low · 1/5 risk factors 0/2 strengths still listed 0/1 reporting maker with supply 5 other companies listing it Medicaid use (2026): ~262 Rx

Reporting: Amneal Pharmaceuticals

Lorlatinib Tablet (Lorbrena) View full page → To Be Discontinued ⚠ Supply risk: High 114 days 1 NDC Oncology First posted Jun 15, 2026 Updated Jun 15, 2026

Pfizer is stopping Lorbrena (lorlatinib) 25 mg tablets in the 120-count bottle, and this change may be permanent. The 30-count bottle of the same strength will continue to be made by Pfizer, with current supply expected to last through June 30, 2026.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply Medicaid use (2026): ~11 Rx

Reporting: Pfizer Inc.

Ifosfamide Injection (IFEX) View full page → Current ⚠ Supply risk: Low 117 days 8 NDCs 4 companies reporting Oncology, Pediatric First posted Jun 12, 2026 Updated Oct 2, 2026

IFEX (ifosfamide) injection is in short supply, with most brand products still available but several generic versions unavailable or limited. The 50 mg/mL strength has no listed source right now; other strengths remain available from some makers, with Hikma expecting more supply around September 2026.

Supply risk: Low · 2/5 risk factors 3/4 strengths still listed 3/4 reporting makers with supply 38% of NDCs unavailable Medicaid use (2026): ~500 Rx

Why: Demand increase for the drug; Requirements related to complying with good manufacturing practices

Reporting: Baxter Healthcare, Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc., SteriMax, Inc.

Dacomitinib Tablet (Vizimpro) View full page → To Be Discontinued ⚠ Supply risk: High 121 days 3 NDCs Oncology First posted Jun 8, 2026 Updated Jun 8, 2026

Pfizer is permanently stopping production of Vizimpro (dacomitinib) tablets. No other manufacturer makes this medicine, so all strengths — 15 mg, 30 mg, and 45 mg — are losing their only listed source.

Supply risk: High · 5/5 risk factors 0/3 strengths still listed 0/1 reporting maker with supply

Reporting: Pfizer Inc.

Leflunomide Tablet (Arava) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 13 other companies list it 121 days 5 NDCs Rheumatology First posted Jun 8, 2026 Updated Jun 8, 2026

Sanofi-Aventis is permanently stopping production of Arava (leflunomide) tablets. Generic leflunomide 10 mg and 20 mg tablets are still listed by other manufacturers; the 100 mg strength has no listed source from any maker right now.

Supply risk: Low · 1/5 risk factors 2/3 strengths still listed 0/1 reporting maker with supply 13 other companies listing it Medicaid use (2025): ~22 Rx

Reporting: Sanofi-Aventis U.S. LLC

Semaglutide Tablet (Rybelsus) View full page → To Be Discontinued ⚠ Supply risk: High 125 days 3 NDCs Endocrinology/Metabolism First posted Jun 4, 2026 Updated Jun 4, 2026

Novo Nordisk is stopping all Rybelsus (semaglutide) tablets, and this change may be permanent. Novo Nordisk states Rybelsus will be replaced by Ozempic (semaglutide) tablets, and no other manufacturer currently lists this medicine as available.

Supply risk: High · 5/5 risk factors 0/3 strengths still listed 0/1 reporting maker with supply Medicaid use (2026): ~193,225 Rx

Reporting: Novo Nordisk, Inc.

Dehydrated Alcohol Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 5 other companies list it 133 days 1 NDC Cardiovascular First posted May 27, 2026 Updated May 27, 2026

Accord Healthcare is discontinuing the 10-pack of Dehydrated Alcohol Injection, and the change may be permanent. Accord is switching to a 5-pack version (NDC 16729-710-53), and other makers still list this medicine as available.

Supply risk: Low · 1/5 risk factors 0/1 size still listed 0/1 reporting maker with supply 5 other companies listing it Medicaid use (2025): ~67 Rx

Reporting: Accord Healthcare Inc.

Gadoterate Meglumine Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 4 other companies list it 139 days 8 NDCs Medical Imaging First posted May 21, 2026 Updated Jun 30, 2026

Fresenius Kabi is permanently stopping production of its gadoterate meglumine injection. The 376.9 mg/mL strength is still listed as available from other manufacturers, including as Dotarem and Clariscan (gadoterate meglumine).

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 4 other companies listing it Medicaid use (2026): ~101 Rx

Reporting: Jiangsu Hengrui Pharmaceuticals Co., Ltd.

Alteplase Injection (Activase) View full page → To Be Discontinued ⚠ Supply risk: High 139 days 1 NDC Cardiovascular, Hematology, Neurology First posted May 21, 2026 Updated May 21, 2026

Genentech is permanently discontinuing the alteplase injection 100 mg vial. The Activase kit, which also contains alteplase, is still listed by Genentech as available.

Supply risk: High · 5/5 risk factors 0/1 size still listed 0/1 reporting maker with supply Medicaid use (2026): ~11 Rx

Reporting: Genentech, Inc

Iron Sucrose Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 4 other companies list it 139 days 1 NDC Hematology First posted May 21, 2026 Updated May 21, 2026

Mylan Institutional is permanently stopping its iron sucrose injection 50 mg/2.5 mL vial. Other strengths and brands — including Venofer (iron sucrose) and generic versions from several makers — are still listed as available.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 4 other companies listing it

Reporting: Mylan Institutional, a Viatris Company

Activated Charcoal Oral Suspension (Actidose Aqua, Actidose) View full page → To Be Discontinued ⚠ Supply risk: High ✓ 1 other company lists it 145 days 5 NDCs Other First posted May 15, 2026 Updated May 15, 2026

Padagis is stopping production of Actidose and Actidose Aqua (activated charcoal oral suspension), and the change may be permanent. A similar product, Insta-Char Aqueous activated charcoal suspension, is still listed by VistaPharm as a possible alternative.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 1 other company listing it Medicaid use (2026): ~100 Rx

Reporting: Padagis US LLC

Sulconazole Nitrate Solution (Exelderm) View full page → To Be Discontinued ⚠ Supply risk: High 152 days 3 NDCs Dermatology First posted May 8, 2026 Updated May 8, 2026

Journey Medical Corporation is permanently stopping sulconazole nitrate 1% solution (sold under their label and for JG Pharma). No other manufacturer of this solution is currently listed as having supply available.

Supply risk: High · 5/5 risk factors 0/3 strengths / sizes still listed 0/1 reporting maker with supply

Reporting: Journey Medical Corporation

Icatibant Acetate Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 7 other companies list it 153 days 2 NDCs Hematology First posted May 7, 2026 Updated May 7, 2026

Fresenius Kabi is permanently stopping its icatibant acetate injection, and no supply from them remains. Other makers — including Takeda, Hikma, Teva, and Eugia — still list icatibant acetate injection, including Firazyr (icatibant acetate), so the medicine has sources available.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 7 other companies listing it

Reporting: Fresenius Kabi USA, LLC

Cisatracurium Besylate Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 10 other companies list it 154 days 3 NDCs Analgesia/Addiction First posted May 6, 2026 Updated Sep 11, 2026

Pfizer (Hospira) is permanently stopping production of cisatracurium besylate injection, with supply expected to run out by late 2026. Other makers — including Hikma, Sandoz, Camber, and Eugia — still list both the 2 mg/mL and 10 mg/mL strengths.

Supply risk: Low · 1/5 risk factors 0/3 strengths still listed 0/1 reporting maker with supply 10 other companies listing it

Reporting: Hospira, Inc., a Pfizer Company

Lamotrigine Extended-Release Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 26 other companies list it 161 days 6 NDCs Neurology First posted Apr 29, 2026 Updated Apr 29, 2026

Par Health is permanently stopping its lamotrigine extended-release tablets. Other strengths of lamotrigine extended-release are still listed by manufacturers that have not reported a shortage, though only orally disintegrating tablets (not extended-release) appear in those listings.

Supply risk: Low · 0/5 risk factors 6/6 strengths still listed 0/1 reporting maker with supply 26 other companies listing it Medicaid use (2026): ~3,649 Rx

Reporting: Par Health, Inc.

Crinecerfont Capsule (Crenessity) View full page → To Be Discontinued ⚠ Supply risk: High 162 days 1 NDC Endocrinology/Metabolism First posted Apr 28, 2026 Updated Apr 28, 2026

Neurocrine Biosciences is stopping the 25 mg capsule of Crenessity (crinecerfont), and this change may be permanent. The 50 mg and 100 mg capsule strengths are not part of this discontinuation, but no other manufacturer lists the 25 mg strength as available.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply

Reporting: Neurocrine Biosciences, Inc.

Etravirine Tablet (Intelence) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 6 other companies list it 162 days 2 NDCs Antiviral First posted Apr 28, 2026 Updated Apr 28, 2026

Janssen is stopping production of Intelence (etravirine) tablets, and this change may be permanent. Other makers not reporting a shortage still list etravirine tablets in 100 mg and 200 mg strengths.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 6 other companies listing it Medicaid use (2026): ~29 Rx

Reporting: Janssen Research and Development

Palbociclib Capsule (Ibrance) View full page → To Be Discontinued ⚠ Supply risk: High 168 days 2 NDCs Oncology First posted Apr 22, 2026 Updated Apr 22, 2026

Pfizer is permanently stopping production of Ibrance (palbociclib) capsules. Pfizer will continue making Ibrance tablets in both the 75 mg and 100 mg strengths as replacements for the capsules.

Supply risk: High · 5/5 risk factors 0/2 strengths still listed 0/1 reporting maker with supply Medicaid use (2025): ~588 Rx

Reporting: Pfizer Inc.

Ketorolac Tromethamine Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 19 other companies list it 170 days 1 NDC Analgesia/Addiction First posted Apr 20, 2026 Updated Apr 20, 2026

Viatris is stopping its manufacture of ketorolac tromethamine 10 mg tablets, and the change may be permanent. Other makers — including Teva, Major Pharmaceuticals, Ajanta Pharma, and Camber — still list the same 10 mg tablet as available.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 19 other companies listing it Medicaid use (2026): ~25,681 Rx

Reporting: Mylan Pharmaceuticals Inc., a Viatris Company

Isocarboxazid Tablet (Marplan) View full page → Current ⚠ Supply risk: Medium 174 days 1 NDC Psychiatry First posted Apr 16, 2026 Updated Aug 6, 2026

Isocarboxazid (Marplan) 10 mg tablets are currently in shortage, though the one manufacturer on record, Lifsa Drugs, still lists some supply available. No other makers of this medicine are on file, so availability may be limited.

Supply risk: Medium · 3/5 risk factors 1/1 strength still listed 1/1 reporting maker with supply 0% of NDCs unavailable

Why: Other

Reporting: Lifsa Drugs LLC

Tiagabine Hydrochloride Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 2 other companies list it 175 days 4 NDCs Neurology First posted Apr 15, 2026 Updated Apr 15, 2026

Teva is permanently stopping production of tiagabine hydrochloride tablets. Other makers — including Sun Pharmaceutical, Cephalon, and Novadoz — have not reported a shortage and still list the 2 mg and 4 mg strengths.

Supply risk: Low · 1/5 risk factors 0/4 strengths still listed 0/1 reporting maker with supply 2 other companies listing it

Reporting: Teva Pharmaceuticals USA, Inc.

Nitroglycerin Ointment (Rectiv) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 5 other companies list it 176 days 1 NDC Analgesia/Addiction First posted Apr 14, 2026 Updated Apr 14, 2026

AbbVie is permanently stopping production of its nitroglycerin 0.4% ointment. Other makers — including Cosette Pharmaceuticals, Encube Ethicals, Trupharma, and Bryant Ranch Prepack — still list nitroglycerin ointment as available.

Supply risk: Low · 1/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 5 other companies listing it Medicaid use (2026): ~369 Rx

Reporting: AbbVie Inc.

Nitrofurantoin Oral Suspension View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 6 other companies list it 180 days 1 NDC Anti-Infective, Other First posted Apr 10, 2026 Updated Apr 10, 2026

Amneal Pharmaceuticals is stopping production of nitrofurantoin oral suspension (25 mg/5 mL), and this change may be permanent. Other makers, including Rising Pharma, Lupin, and Aurobindo, still list nitrofurantoin oral suspension at both 25 mg/5 mL and 50 mg/5 mL strengths.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 6 other companies listing it Medicaid use (2026): ~2,195 Rx

Reporting: Amneal Pharmaceuticals

Azithromycin Tablet (Zithromax) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 22 other companies list it 181 days 2 NDCs Anti-Infective First posted Apr 9, 2026 Updated Apr 9, 2026

Pfizer is permanently stopping production of Zithromax (azithromycin) tablets. Other makers, including Sandoz and Lannett, still list the 250 mg and 500 mg tablets as available, so the medicine can still be found from other sources.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 22 other companies listing it Medicaid use (2026): ~110 Rx

Reporting: Pfizer Inc.

Aprepitant Oral Powder for Suspension (Emend) View full page → To Be Discontinued ⚠ Supply risk: High 182 days 1 NDC Gastroenterology First posted Apr 8, 2026 Updated Apr 8, 2026

Merck is stopping aprepitant oral powder for suspension (125 mg), and this change may be permanent. No other manufacturers of this form are listed as having supply available right now.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply Medicaid use (2026): ~257 Rx

Reporting: Merck Sharp & Dohme LLC

Fosaprepitant Dimeglumine Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 16 other companies list it 182 days 1 NDC Gastroenterology First posted Apr 8, 2026 Updated Apr 8, 2026

Fresenius Kabi is permanently stopping production of its fosaprepitant dimeglumine injection. The 150 mg/5 mL strength is still listed by other manufacturers, including as Emend (fosaprepitant dimeglumine).

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 16 other companies listing it Medicaid use (2026): ~630 Rx

Reporting: Fresenius Kabi USA, LLC

Idelalisib Tablet (Zydelig) View full page → To Be Discontinued ⚠ Supply risk: High 183 days 2 NDCs Oncology First posted Apr 7, 2026 Updated Apr 7, 2026

Gilead Sciences is stopping Zydelig (idelalisib) tablets, and this change may be permanent. No other makers list either the 100 mg or 150 mg strength, so there is currently no listed source for this medicine.

Supply risk: High · 5/5 risk factors 0/2 strengths still listed 0/1 reporting maker with supply

Reporting: Gilead Sciences, Inc.

Ursodiol Capsule View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 20 other companies list it 184 days 1 NDC Other First posted Apr 6, 2026 Updated Apr 6, 2026

Strides Pharma is permanently stopping its ursodiol 300 mg capsules. Other manufacturers — including Lannett, Actavis, Major Pharmaceuticals, and KVK-Tech — still list ursodiol 300 mg capsules as available.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 20 other companies listing it Medicaid use (2026): ~1,218 Rx

Reporting: Strides Pharma Inc.

Icosapent Ethyl Capsule View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 13 other companies list it 189 days 2 NDCs Cardiovascular First posted Apr 1, 2026 Updated Apr 1, 2026

Apotex is permanently stopping its icosapent ethyl capsules. The 1 g strength is still listed as available from other makers, including Hikma, Teva, Northstar Rx, and Camber Pharmaceuticals.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 13 other companies listing it

Reporting: Apotex Corp.

Furosemide Oral Solution View full page → Current ⚠ Supply risk: Low ✓ 1 other company lists it 190 days 3 NDCs Cardiovascular First posted Mar 31, 2026 Updated Sep 18, 2026

Furosemide oral solution is in short supply because of a shortage of an inactive ingredient. Hikma still lists both the 40 mg/5 mL and 10 mg/mL strengths but is filling orders on allocation only; Precision Dose also lists furosemide oral solution from outside the shortage.

Supply risk: Low · 2/5 risk factors 2/2 strengths still listed 1/1 reporting maker with supply 1 other company listing it 0% of NDCs unavailable Medicaid use (2025): ~44,171 Rx

Why: Shortage of an inactive ingredient component

Reporting: Hikma Pharmaceuticals USA, Inc.

Dapsone Gel View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 13 other companies list it 194 days 1 NDC Dermatology First posted Mar 27, 2026 Updated Mar 27, 2026

Amneal Pharmaceuticals is permanently stopping production of dapsone gel 7.5%. Other brands and generics of dapsone gel, including Aczone (dapsone) gel, are still listed by other manufacturers.

Supply risk: Low · 1/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 13 other companies listing it Medicaid use (2025): ~633 Rx

Reporting: Amneal Pharmaceuticals

Progesterone Vaginal Gel (Crinone) View full page → To Be Discontinued ⚠ Supply risk: High 194 days 1 NDC Urology First posted Mar 27, 2026 Updated Mar 27, 2026

AbbVie is permanently stopping production of Crinone (progesterone vaginal gel) 4%. No other makers of this gel are currently listed as having supply available.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply Medicaid use (2025): ~33 Rx

Reporting: AbbVie Inc.

Tazemetostat Hydrobromide Tablet (Tazverik) View full page → To Be Discontinued ⚠ Supply risk: High 194 days 1 NDC Oncology First posted Mar 27, 2026 Updated Mar 27, 2026

Epizyme is permanently stopping production of Tazemetostat Hydrobromide tablets (the cancer medicine sold as Tazverik), and no supply remains. No other manufacturer of this medicine has been found in our records.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply Medicaid use (2025): ~97 Rx

Reporting: Epizyme, Inc. (An Ipsen Company)

Nebivolol Hydrochloride Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 20 other companies list it 196 days 16 NDCs Cardiovascular First posted Mar 25, 2026 Updated Mar 25, 2026

Torrent Pharmaceuticals is permanently stopping its generic nebivolol hydrochloride tablets in all strengths. Bystolic (nebivolol hydrochloride) tablets in all four strengths are still listed by other manufacturers not reporting a shortage.

Supply risk: Low · 0/5 risk factors 4/4 strengths still listed 0/1 reporting maker with supply 20 other companies listing it

Reporting: Torrent Pharmaceuticals Limited

Ivabradine Hydrochloride Tablet (Corlanor) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 9 other companies list it 197 days 2 NDCs Cardiovascular First posted Mar 24, 2026 Updated Mar 24, 2026

Amgen is permanently stopping its version of ivabradine hydrochloride tablets. Other manufacturers — including Camber Pharmaceuticals, Ingenus Pharmaceuticals, and Golden State Medical Supply — still list both the 5 mg and 7.5 mg strengths as available.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 9 other companies listing it Medicaid use (2025): ~6,290 Rx

Reporting: Amgen Inc.

Ivabradine Solution (Corlanor) View full page → To Be Discontinued ⚠ Supply risk: High 197 days 1 NDC Cardiovascular First posted Mar 24, 2026 Updated Mar 24, 2026

Amgen is permanently stopping production of ivabradine oral solution (5 mg/5 mL). No other manufacturer of this form is currently listed as having supply available.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply Medicaid use (2026): ~164 Rx

Reporting: Amgen Inc.

Pilocarpine Hydrochloride Ophthalmic Solution (Vuity) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 4 other companies list it 197 days 5 NDCs Ophthalmology First posted Mar 24, 2026 Updated Mar 24, 2026

AbbVie is permanently stopping production of Vuity (pilocarpine hydrochloride) eye drops. Other manufacturers not reporting a shortage still list pilocarpine hydrochloride eye drops in multiple strengths as available.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 4 other companies listing it Medicaid use (2026): ~743 Rx

Reporting: AbbVie Inc.

Pentamidine Isethionate Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 4 other companies list it 198 days 1 NDC Anti-Infective First posted Mar 23, 2026 Updated Mar 23, 2026

XGen Pharmaceuticals is permanently stopping its pentamidine isethionate injection. Other manufacturers — including Fresenius Kabi and Seton Pharmaceuticals — still list this medicine, including Pentam 300 (pentamidine isethionate) 300 mg, so supply may be available from other sources.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 4 other companies listing it

Reporting: XGen Pharmaceuticals DJB, Inc.

Ramelteon Tablet (Rozerem) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 17 other companies list it 202 days 2 NDCs Psychiatry First posted Mar 19, 2026 Updated Mar 19, 2026

Rozerem (ramelteon) tablets are being discontinued by Takeda Pharmaceuticals. The 8 mg strength is still listed by other makers, including Actavis Pharma, Upsher-Smith Laboratories, Major Pharmaceuticals, and AvKARE.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 17 other companies listing it Medicaid use (2026): ~15,832 Rx

Reporting: Takeda Pharmaceuticals USA Inc.

Plerixafor Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 7 other companies list it 208 days 1 NDC Hematology First posted Mar 13, 2026 Updated Mar 13, 2026

Fresenius Kabi is permanently stopping its plerixafor injection, a medicine used to help collect stem cells for transplant. Other makers — including the brand Mozobil (plerixafor) from Sanofi-Aventis — have not reported a shortage and still list supply.

Supply risk: Low · 1/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 7 other companies listing it

Reporting: Fresenius Kabi USA, LLC

Peritoneal Dialysis Solution (DELFLEX w/Dextrose) View full page → To Be Discontinued ⚠ Supply risk: High 211 days 6 NDCs Renal First posted Mar 10, 2026 Updated Mar 10, 2026

DELFLEX® w/Dextrose (peritoneal dialysis solution) is being discontinued by Fresenius Medical Care. The product will be replaced with items under a new labeling code, and no other manufacturers currently list this solution as available.

Supply risk: High · 5/5 risk factors 0/6 strengths still listed 0/1 reporting maker with supply

Reporting: Fresenius Medical Care North America

Clindamycin Palmitate Hydrochloride Injection View full page → To Be Discontinued ⚠ Supply risk: High 222 days 2 NDCs Anti-Infective First posted Feb 27, 2026 Updated Mar 26, 2026

Amneal Pharmaceuticals is stopping production of Clindamycin Palmitate Hydrochloride Injection (75 mg/5 mL), and this change may be permanent. No other manufacturers are currently listed as a source for this medicine.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply Medicaid use (2026): ~460 Rx

Reporting: Amneal Pharmaceuticals

Itraconazole Capsule (Sporanox) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 9 other companies list it 222 days 3 NDCs Anti-Infective, Other First posted Feb 27, 2026 Updated Feb 27, 2026

Janssen Pharmaceuticals is permanently stopping its itraconazole 100 mg capsules. Other makers — including Torrent Pharmaceuticals, Rising Pharma, NorthStar Rx, and AvPAK — have not reported a shortage and still list this medicine as available.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 9 other companies listing it Medicaid use (2026): ~484 Rx

Reporting: Janssen Pharmaceuticals

Lincomycin Hydrochloride Injection (Lincocin) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 2 other companies list it 224 days 3 NDCs 2 companies reporting Anti-Infective First posted Feb 25, 2026 Updated Mar 26, 2026

Lincocin (lincomycin hydrochloride) injection is being discontinued by both Pfizer and XGen Pharmaceuticals, and this change may be permanent. Lincocin is still listed as available from other manufacturers not reporting a shortage.

Supply risk: Low · 1/5 risk factors 0/3 strengths / sizes still listed 0/2 reporting makers with supply 2 other companies listing it Medicaid use (2026): ~446 Rx

Reporting: Pfizer Inc., XGen Pharmaceuticals DJB, Inc.

Clindamycin Hydrochloride Capsule (Cleocin Hydrochloride) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 18 other companies list it 224 days 3 NDCs Anti-Infective First posted Feb 25, 2026 Updated Feb 25, 2026

Pfizer is permanently stopping its Cleocin Hydrochloride (clindamycin hydrochloride) capsules. The same capsules in 75 mg, 150 mg, and 300 mg strengths are still listed by other manufacturers that have not reported a shortage.

Supply risk: Low · 0/5 risk factors 3/3 strengths still listed 0/1 reporting maker with supply 18 other companies listing it Medicaid use (2026): ~11 Rx

Reporting: Pfizer Inc.

Arsenic Trioxide Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 12 other companies list it 225 days 2 NDCs 2 companies reporting Oncology First posted Feb 24, 2026 Updated Sep 21, 2026

Both Fresenius Kabi and Ingenus Pharmaceuticals are permanently stopping production of arsenic trioxide injection. Other makers — including Sandoz, Nexus Pharmaceuticals, Heritage Pharma, and Sagent Pharmaceuticals — still list arsenic trioxide injection in both 1 mg/mL and 2 mg/mL strengths as available.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/2 reporting makers with supply 12 other companies listing it Medicaid use (2026): ~956 Rx

Reporting: Fresenius Kabi USA, LLC, Ingenus Pharmaceuticals LLC

Irinotecan Hydrochloride Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 12 other companies list it 225 days 2 NDCs Oncology First posted Feb 24, 2026 Updated Feb 24, 2026

Ingenus Pharmaceuticals is permanently stopping its irinotecan hydrochloride injection, a chemotherapy medicine used to treat certain cancers. Other manufacturers — including the makers of Camptosar (irinotecan hydrochloride) — have not reported a shortage, so supply may still be available from other sources.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 12 other companies listing it Medicaid use (2026): ~564 Rx

Reporting: Ingenus Pharmaceuticals LLC

Decitabine Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 14 other companies list it 229 days 2 NDCs Oncology First posted Feb 20, 2026 Updated Feb 20, 2026

BluePoint Laboratories is permanently stopping its decitabine injection. The 50 mg form is still listed as available from other manufacturers, including Hikma, Accord Healthcare, Sagent, and Camber Pharmaceuticals.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 14 other companies listing it Medicaid use (2025): ~18 Rx

Reporting: Ingenus Pharmaceuticals LLC

Docetaxel Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 18 other companies list it 229 days 2 NDCs Oncology First posted Feb 20, 2026 Updated Feb 20, 2026

Ingenus Pharmaceuticals is permanently discontinuing its docetaxel injection 10 mg/mL. Other manufacturers — including Hikma, Hospira, Sanofi-Aventis, and Accord Healthcare — still list docetaxel injection in other strengths and forms.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 18 other companies listing it

Reporting: Ingenus Pharmaceuticals LLC

Allopurinol Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 28 other companies list it 230 days 4 NDCs Oncology, Renal, Rheumatology First posted Feb 19, 2026 Updated Feb 19, 2026

Teva is permanently stopping its allopurinol tablets. Both the 100 mg and 300 mg strengths are still listed by other makers, including Mylan, Par, Major Pharmaceuticals, and Rising Pharma.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 28 other companies listing it Medicaid use (2026): ~3,933 Rx

Reporting: Teva Pharmaceuticals USA, Inc.

Cefepime Hydrochloride Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 6 other companies list it 239 days 2 NDCs Anti-Infective First posted Feb 10, 2026 Updated Feb 10, 2026

Fresenius Kabi is permanently stopping its cefepime hydrochloride injection, and this change may be lasting. The same medicine in both 1 g and 2 g strengths is still listed as available from other manufacturers, including Hikma, Hospira, Sagent, and WG Critical Care.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 6 other companies listing it Medicaid use (2026): ~140 Rx

Reporting: Fresenius Kabi USA, LLC

Chlorothiazide Oral Suspension (Diuril) View full page → To Be Discontinued ⚠ Supply risk: High 239 days 1 NDC Cardiovascular First posted Feb 10, 2026 Updated Feb 10, 2026

Diuril (chlorothiazide) oral suspension is being permanently discontinued by its manufacturer. No other maker of this suspension is currently listed, so there is no known alternative source for this form of the medicine right now.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply Medicaid use (2026): ~7,744 Rx

Reporting: Salix Pharmaceuticals, a division of Bausch Health US, LLC

Gemfibrozil Tablet (Lopid) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 18 other companies list it 239 days 1 NDC Endocrinology/Metabolism First posted Feb 10, 2026 Updated Feb 10, 2026

Pfizer is permanently stopping production of gemfibrozil 600 mg tablets. The same medicine — including Lopid (gemfibrozil) 600 mg — is still listed as available from other manufacturers not reporting a shortage.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 18 other companies listing it

Reporting: Pfizer Inc.

Pindolol Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 6 other companies list it 250 days 2 NDCs Cardiovascular First posted Jan 30, 2026 Updated Jan 30, 2026

Sun Pharmaceutical is permanently stopping production of pindolol tablets, with the last batches expiring by early 2027. Both the 5 mg and 10 mg strengths are still listed by other manufacturers, including Marlex Pharmaceuticals, ANI Pharmaceuticals, Westminster Pharmaceuticals, and Bryant Ranch Prepack.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 6 other companies listing it Medicaid use (2026): ~863 Rx

Reporting: Sun Pharmaceutical Industries, Inc.

Podofilox Topical Gel (Condylox) View full page → To Be Discontinued ⚠ Supply risk: High ✓ 1 other company lists it 252 days 1 NDC Dermatology, Other First posted Jan 28, 2026 Updated Jan 28, 2026

AbbVie is permanently stopping production of Podofilox 0.5% topical gel. The same medicine in gel form is still listed as available from Padagis.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 1 other company listing it Medicaid use (2026): ~332 Rx

Reporting: AbbVie Inc.

Benztropine Mesylate Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 2 other companies list it 253 days 1 NDC Neurology First posted Jan 27, 2026 Updated Jan 27, 2026

Fresenius Kabi is permanently stopping production of benztropine mesylate injection. The 1 mg/mL strength is still listed as available from other manufacturers not reporting a shortage.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 2 other companies listing it

Reporting: Fresenius Kabi USA, LLC

Fluvastatin Sodium Extended-Release Tablet (Lescol XL) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 2 other companies list it 253 days 3 NDCs Cardiovascular First posted Jan 27, 2026 Updated Jan 27, 2026

Sandoz is stopping all of its Lescol XL (fluvastatin) extended-release tablets, and this change may be permanent. The 80 mg generic version is still listed by other makers who have not reported a shortage.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 2 other companies listing it

Reporting: Sandoz Inc.

Azithromycin Injection (Zithromax IV) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 6 other companies list it 260 days 1 NDC Anti-Infective First posted Jan 20, 2026 Updated Jan 20, 2026

Pfizer is permanently stopping production of Zithromax IV (azithromycin injection). The same medicine at the 500 mg strength is still listed as available from other manufacturers, including Sagent Pharmaceuticals, Eugia US LLC, Sun Pharmaceutical Industries, and Fresenius Kabi USA.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 6 other companies listing it Medicaid use (2026): ~535 Rx

Reporting: Pfizer Inc.

Maraviroc Solution (Selzentry) View full page → To Be Discontinued ⚠ Supply risk: High 260 days 1 NDC Antiviral First posted Jan 20, 2026 Updated Jan 20, 2026

Selzentry (maraviroc) oral solution is being discontinued — ViiV Healthcare plans to stop distributing it around August 1, 2026. No other manufacturers of this oral solution appear in our records.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply

Reporting: ViiV Healthcare Company

Piperacillin and Tazobactam Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 10 other companies list it 260 days 1 NDC Anti-Infective First posted Jan 20, 2026 Updated Jan 20, 2026

Fresenius Kabi is permanently stopping its piperacillin-tazobactam injection 2.25 g vials. Other manufacturers — including B. Braun Medical, Sagent Pharmaceuticals, WG Critical Care, and Eugia — still list piperacillin-tazobactam in multiple strengths and forms.

Supply risk: Low · 1/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 10 other companies listing it Medicaid use (2026): ~13 Rx

Reporting: Fresenius Kabi USA, LLC

Riboflavin 5-Phosphate Ophthalmic Solution (Photrexa Cross-linking Kit) View full page → To Be Discontinued ⚠ Supply risk: High 260 days 1 NDC Ophthalmology First posted Jan 20, 2026 Updated Jan 20, 2026

Glaukos Corporation is stopping production of the Photrexa Cross-linking Kit (riboflavin 5-phosphate ophthalmic solution), and this change may be permanent. No other manufacturer of this medicine has been identified in FDA shortage records.

Supply risk: High · 4/5 risk factors 0/1 reporting maker with supply Medicaid use (2026): ~862 Rx

Reporting: Glaukos Corporation

Adalimumab-adaz Injection (Hyrimoz) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 1 other company lists it 267 days 5 NDCs Rheumatology First posted Jan 13, 2026 Updated Jan 13, 2026

Sandoz is stopping its version of Hyrimoz (adalimumab-adaz) injection, and this change may be permanent. Sandoz notes an equivalent Sandoz format is available; Hyrimoz is also still listed by Cordavis in multiple strengths.

Supply risk: Low · 2/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 1 other company listing it

Reporting: Sandoz Inc.

Caspofungin Acetate Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 3 other companies list it 268 days 3 NDCs 2 companies reporting Anti-Infective First posted Jan 12, 2026 Updated Jun 30, 2026

Sandoz and Fresenius Kabi are permanently stopping production of their caspofungin acetate injection. The same medicine — including Cancidas (caspofungin acetate) — is still listed as available from other manufacturers not reporting a shortage.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/2 reporting makers with supply 3 other companies listing it Medicaid use (2026): ~161 Rx

Reporting: Fresenius Kabi USA, LLC, Jiangsu Hengrui Pharmaceuticals Co. (US Agent eVenus Pharmaceutical Laboratories, Inc.)

Doxycycline Hyclate Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 45 other companies list it 268 days 2 NDCs Anti-Infective First posted Jan 12, 2026 Updated Jan 12, 2026

Viatris (through its Mylan unit) is permanently stopping its doxycycline hyclate tablets. The 100 mg tablet is still listed as available from other manufacturers not reporting a shortage.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 45 other companies listing it

Reporting: Mylan Pharmaceuticals Inc., a Viatris Company

Doxylamine Succinate and Pyridoxine Hydrochloride Delayed-Release Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 6 other companies list it 268 days 1 NDC Other First posted Jan 12, 2026 Updated Jan 12, 2026

Viatris (formerly Mylan) is permanently stopping its doxylamine-pyridoxine delayed-release tablets. The same 10 mg strength is still listed by other makers, including the brand Diclegis (doxylamine-pyridoxine) from Duchesnay USA.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 6 other companies listing it Medicaid use (2025): ~3,325 Rx

Reporting: Mylan Pharmaceuticals Inc., a Viatris Company

Neostigmine Methylsulfate Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 15 other companies list it 268 days 1 NDC Analgesia/Addiction First posted Jan 12, 2026 Updated Jan 12, 2026

Fresenius Kabi is permanently stopping its neostigmine methylsulfate injection. Other manufacturers have not reported a shortage and still list this medicine as available.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 15 other companies listing it

Reporting: Fresenius Kabi USA, LLC

Haloperidol Decanoate Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 13 other companies list it 271 days 2 NDCs Psychiatry First posted Jan 9, 2026 Updated Jan 9, 2026

Fresenius Kabi is permanently stopping production of haloperidol decanoate injection 50 mg/mL. Other makers — including Hikma, Patriot Pharmaceuticals, Sagent, and Janssen — still list both the 50 mg/mL and 100 mg/mL strengths as available.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 13 other companies listing it Medicaid use (2026): ~546 Rx

Reporting: Fresenius Kabi USA, LLC

Imipenem and Cilastatin Injection (Primaxin) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 2 other companies list it 272 days 1 NDC Anti-Infective First posted Jan 8, 2026 Updated Jan 8, 2026

Merck Sharp & Dohme is discontinuing Primaxin (imipenem and cilastatin) injection, and the change is expected to be permanent around November 30, 2026. Other makers — WG Critical Care and Fresenius Kabi — have not reported a shortage and still list this medicine in 250 mg and 500 mg strengths.

Supply risk: Low · 1/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 2 other companies listing it Medicaid use (2025): ~14 Rx

Reporting: Merck Sharp & Dohme Corp.

Diltiazem Hydrochloride Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 3 other companies list it 275 days 1 NDC Cardiovascular First posted Jan 5, 2026 Updated Jan 5, 2026

Pfizer (Hospira) is permanently stopping its diltiazem hydrochloride injection. The 5 mg/mL injectable form of this medicine is still listed as available from other manufacturers.

Supply risk: Low · 1/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 3 other companies listing it Medicaid use (2026): ~18 Rx

Reporting: Hospira, Inc., a Pfizer Company

Hydroxychloroquine Sulfate Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 21 other companies list it 275 days 1 NDC Anti-Infective, Other, Rheumatology First posted Jan 5, 2026 Updated Jan 5, 2026

Teva is permanently stopping its hydroxychloroquine sulfate tablets. The 200 mg tablet is still listed as available from other manufacturers, including Major Pharmaceuticals, Rising Pharma, Northstar Rx, and Accord Healthcare.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 21 other companies listing it Medicaid use (2026): ~6,292 Rx

Reporting: Teva Pharmaceuticals USA, Inc.

Sodium Oxybate Solution View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 3 other companies list it 282 days 1 NDC Psychiatry First posted Dec 29, 2025 Updated Dec 29, 2025

Amneal Pharmaceuticals is stopping its sodium oxybate solution, and the change may be permanent. The same medicine is still listed by other makers, including Xyrem (sodium oxybate) solution from Jazz Pharmaceuticals.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 3 other companies listing it

Reporting: Amneal Pharmaceuticals

Mirikizumab-mrkz Injection (Omvoh) View full page → To Be Discontinued ⚠ Supply risk: High 289 days 2 NDCs Gastroenterology, Other First posted Dec 22, 2025 Updated Dec 22, 2025

Eli Lilly is permanently discontinuing Omvoh (mirikizumab-mrkz) 100 mg/1 mL injection, with distribution ending April 2026. The 200 mg/2 mL presentation of Omvoh will remain available as a replacement.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply Medicaid use (2026): ~144 Rx

Reporting: Eli Lilly and Co.

Morphine Sulfate Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 9 other companies list it 289 days 2 NDCs Analgesia/Addiction First posted Dec 22, 2025 Updated Dec 22, 2025

Upsher-Smith is permanently stopping its morphine sulfate tablets (15 mg and 30 mg). Other makers — including Hikma, SpecGx, and Major Pharmaceuticals — still list both strengths as available.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 9 other companies listing it Medicaid use (2026): ~3,839 Rx

Reporting: Upsher-Smith Laboratories, LLC

Carbamazepine Extended-Release Capsule (Carbatrol) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 5 other companies list it 292 days 3 NDCs Neurology First posted Dec 19, 2025 Updated Dec 19, 2025

Takeda Pharmaceuticals is permanently discontinuing its carbamazepine extended-release capsules. Other manufacturers — including Major Pharmaceuticals, AvPAK, Apotex, and ANI Pharmaceuticals — still list the 100 mg, 200 mg, and 300 mg strengths as available.

Supply risk: Low · 0/5 risk factors 3/3 strengths still listed 0/1 reporting maker with supply 5 other companies listing it Medicaid use (2026): ~13,881 Rx

Reporting: Takeda Pharmaceuticals USA Inc.

Doxercalciferol Injection (Hectorol) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 4 other companies list it 301 days 3 NDCs Endocrinology/Metabolism First posted Dec 10, 2025 Updated Dec 10, 2025

Sanofi-Aventis is permanently stopping Hectorol (doxercalciferol) injection. Generic doxercalciferol injection is still listed by other manufacturers who have not reported a shortage.

Supply risk: Low · 1/5 risk factors 0/3 strengths still listed 0/1 reporting maker with supply 4 other companies listing it

Reporting: Sanofi-Aventis U.S. LLC

Spironolactone Tablet (Aldactone) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 21 other companies list it 301 days 2 NDCs Cardiovascular First posted Dec 10, 2025 Updated Dec 10, 2025

Pfizer is stopping production of spironolactone tablets, and this change may be permanent. The same medicine is still listed by other makers not reporting a shortage, including 25 mg, 50 mg, and 100 mg strengths.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 21 other companies listing it

Reporting: Pfizer Inc.

Ampicillin Sodium Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 8 other companies list it 303 days 5 NDCs Anti-Infective First posted Dec 8, 2025 Updated Dec 8, 2025

Sandoz is stopping its private-label ampicillin sodium injection, and this change may be permanent. Other makers — including Sagent Pharmaceuticals and WG Critical Care — still list ampicillin sodium injection in multiple strengths, so the medicine remains available from other sources.

Supply risk: Low · 0/5 risk factors 3/3 strengths still listed 0/1 reporting maker with supply 8 other companies listing it Medicaid use (2026): ~147 Rx

Reporting: Sandoz Inc.

Calcitriol Capsule View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 12 other companies list it 307 days 2 NDCs Endocrinology/Metabolism First posted Dec 4, 2025 Updated Dec 4, 2025

Teva is permanently stopping its calcitriol capsules — this is a business decision, not a temporary shortage. Other makers still list calcitriol capsules in both 0.25 mcg and 0.5 mcg strengths, so the medicine may still be available through other sources.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 12 other companies listing it Medicaid use (2026): ~9,505 Rx

Reporting: Teva Pharmaceuticals USA, Inc.

Sodium Chloride 0.9% Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 12 other companies list it 308 days 3 NDCs Gastroenterology, Other, Renal First posted Dec 3, 2025 Updated Dec 3, 2025

Pfizer (Hospira) is permanently stopping its Sodium Chloride 0.9% Injection in ADD-Vantage flexible containers (50 mL, 100 mL, and 250 mL sizes). Other makers — including B. Braun, Baxter, Nephron, and ICU Medical — still list sodium chloride 0.9% injection as available.

Supply risk: Low · 1/5 risk factors 0/3 sizes still listed 0/1 reporting maker with supply 12 other companies listing it Medicaid use (2026): ~12,377 Rx

Reporting: Hospira, Inc., a Pfizer Company

Posaconazole Injection (Noxafil) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 2 other companies list it 309 days 1 NDC Anti-Infective First posted Dec 2, 2025 Updated Dec 2, 2025

Merck is stopping production of posaconazole injection (18 mg/mL), and this change may be permanent. The same medicine is still listed as available from other makers not reporting a shortage.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 2 other companies listing it Medicaid use (2025): ~28 Rx

Reporting: Merck Sharp & Dohme Corp.

Nilutamide Tablet (Nilandron) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 1 other company lists it 310 days 2 NDCs Oncology First posted Dec 1, 2025 Updated Dec 1, 2025

Advanz Pharma is stopping production of nilutamide 150 mg tablets, and this change is permanent. The same strength is still listed as available from ANI Pharmaceuticals.

Supply risk: Low · 2/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 1 other company listing it

Reporting: Advanz Pharma (US) Corp.

Phenoxybenzamine Hydrochloride Capsule (Dibenzyline) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 3 other companies list it 310 days 3 NDCs Cardiovascular First posted Dec 1, 2025 Updated Dec 1, 2025

Advanz Pharma is permanently stopping production of Dibenzyline (phenoxybenzamine hydrochloride) capsules. The 10 mg capsule is still listed by other manufacturers not reporting a shortage.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 3 other companies listing it

Reporting: Advanz Pharma (US) Corp.

Potassium Chloride Extended-Release Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 27 other companies list it 320 days 4 NDCs Endocrinology/Metabolism, Gastroentero... First posted Nov 21, 2025 Updated Nov 21, 2025

Teva is permanently stopping its potassium chloride extended-release tablets. Other makers have not reported a shortage, and Klor-Con (potassium chloride) extended-release tablets in several strengths remain listed as available from them.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 27 other companies listing it Medicaid use (2026): ~26,872 Rx

Reporting: Teva Pharmaceuticals USA, Inc.

Verapamil Hydrochloride Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 15 other companies list it 320 days 1 NDC Cardiovascular First posted Nov 21, 2025 Updated Nov 21, 2025

Pfizer is permanently stopping production of Verapamil Hydrochloride Injection 2.5 mg/mL. Other makers — including Hospira, Sagent, and Micro Labs — still list this same strength as available.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 15 other companies listing it

Reporting: Pfizer Inc.

Anagrelide Hydrochloride Capsule View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 4 other companies list it 322 days 2 NDCs Hematology First posted Nov 19, 2025 Updated Nov 19, 2025

Teva is permanently stopping its anagrelide hydrochloride capsules — a business decision that will not be reversed. Other makers, including those that sell Agrylin (anagrelide) and generic versions in both 0.5 mg and 1 mg capsules, have not reported a shortage.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 4 other companies listing it

Reporting: Teva Pharmaceuticals USA, Inc.

Hydrochlorothiazide Capsule (Microzide) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 15 other companies list it 322 days 2 NDCs Cardiovascular First posted Nov 19, 2025 Updated Nov 19, 2025

Teva is permanently stopping its hydrochlorothiazide 12.5 mg capsules. Other makers, including Actavis Pharma and Unichem Pharmaceuticals, still list this same strength and form as available.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 15 other companies listing it Medicaid use (2025): ~4,367 Rx

Reporting: Teva Pharmaceuticals USA, Inc.

Valsartan Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 21 other companies list it 322 days 4 NDCs Cardiovascular First posted Nov 19, 2025 Updated Nov 19, 2025

Mylan is permanently stopping its valsartan tablets — a business decision, not a temporary shortage. Other makers, including the brand Diovan (valsartan), still list the same strengths as available sources.

Supply risk: Low · 0/5 risk factors 4/4 strengths still listed 0/1 reporting maker with supply 21 other companies listing it Medicaid use (2025): ~50,661 Rx

Reporting: Mylan Pharmaceuticals Inc., a Viatris Company

Montelukast Sodium Chewable Tablet (Singulair) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 26 other companies list it 324 days 1 NDC Pulmonary/Allergy First posted Nov 17, 2025 Updated Nov 17, 2025

Organon is permanently stopping production of its chewable montelukast sodium 4 mg tablets. Other makers not reporting a shortage still list chewable montelukast sodium 4 mg tablets as available.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 26 other companies listing it

Reporting: Organon

Ceftazidime Injection (Tazicef) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 2 other companies list it 327 days 2 NDCs Anti-Infective First posted Nov 14, 2025 Updated Nov 14, 2025

Pfizer (Hospira) is permanently stopping production of its ceftazidime injection. Other makers — including Sagent Pharmaceuticals and WG Critical Care — still list ceftazidime injection in 2 g and 6 g strengths, so the medicine remains available from other sources.

Supply risk: Low · 1/5 risk factors 1/2 strengths still listed 0/1 reporting maker with supply 2 other companies listing it

Reporting: Hospira, Inc., a Pfizer Company

Palonosetron Hydrochloride Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 13 other companies list it 327 days 1 NDC Gastroenterology First posted Nov 14, 2025 Updated Nov 14, 2025

Teva is permanently stopping production of palonosetron hydrochloride injection. Other makers — including Sandoz, NorthStar Rx, Sagent, and Baxter — still list this medicine as available.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 13 other companies listing it Medicaid use (2026): ~6,675 Rx

Reporting: Teva Pharmaceuticals USA, Inc.

Somatropin Injection (Norditropin) View full page → To Be Discontinued ⚠ Supply risk: High ✓ 1 other company lists it 327 days 1 NDC Endocrinology/Metabolism First posted Nov 14, 2025 Updated Nov 14, 2025

Novo Nordisk is stopping its somatropin injection 30 mg/3 mL, and this change may be permanent. Other somatropin products, including Norditropin (somatropin) in several strengths, are still listed as available from makers that have not reported a shortage.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 1 other company listing it

Reporting: Novo Nordisk, Inc.

Vancomycin Hydrochloride Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 15 other companies list it 327 days 1 NDC Anti-Infective First posted Nov 14, 2025 Updated Nov 14, 2025

Pfizer (Hospira) is permanently stopping production of the NovaPlus vancomycin hydrochloride 10 g injection vial. Other strengths of vancomycin hydrochloride injection are still listed as available from other manufacturers.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 15 other companies listing it Medicaid use (2026): ~246 Rx

Reporting: Hospira, Inc., a Pfizer Company

Adalimumab-ryvk Kit (Simlandi) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 2 other companies list it 328 days 1 NDC Rheumatology First posted Nov 13, 2025 Updated Nov 13, 2025

Teva is permanently stopping production of Simlandi (adalimumab-ryvk) kits. The same medicine is still listed by other makers who have not reported a shortage.

Supply risk: Low · 0/5 risk factors 0/1 reporting maker with supply 2 other companies listing it

Reporting: Teva Pharmaceuticals USA, Inc.

Cetrorelix Acetate Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 4 other companies list it 328 days 1 NDC Reproductive First posted Nov 13, 2025 Updated Nov 13, 2025

Teva is permanently stopping production of its cetrorelix acetate injection. Other makers — including the brand Cetrotide (cetrorelix acetate) — still list supply, so the medicine remains available from those sources.

Supply risk: Low · 0/5 risk factors 0/1 reporting maker with supply 4 other companies listing it

Reporting: Teva Pharmaceuticals USA, Inc.

Guanfacine Hydrochloride Extended-Release Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 17 other companies list it 328 days 4 NDCs Psychiatry First posted Nov 13, 2025 Updated Nov 13, 2025

Actavis Pharma is permanently stopping its guanfacine extended-release tablets. All four strengths (1 mg, 2 mg, 3 mg, and 4 mg) are still listed as available from other manufacturers, including Northstar RxLLC, Upsher-Smith Laboratories, and Unichem Pharmaceuticals.

Supply risk: Low · 0/5 risk factors 4/4 strengths still listed 0/1 reporting maker with supply 17 other companies listing it Medicaid use (2026): ~355,678 Rx

Reporting: Actavis Pharma, Inc.

Frovatriptan Succinate Tablet (Frova) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 3 other companies list it 329 days 2 NDCs Neurology First posted Nov 12, 2025 Updated Feb 24, 2026

Endo Pharmaceuticals is permanently stopping Frova (frovatriptan) tablets. The 2.5 mg tablet is still listed as available from other manufacturers who have not reported a shortage.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 3 other companies listing it

Reporting: Endo Pharmaceuticals, Inc.

Calcium Chloride Injection View full page → To Be Discontinued ⚠ Supply risk: High 334 days 1 NDC Cardiovascular, Endocrinology/Metaboli... First posted Nov 7, 2025 Updated Nov 7, 2025

Hospira (a Pfizer company) is stopping production of Calcium Chloride Injection 100 mg/mL, and this change may be permanent. No other manufacturers are currently listed as a source for this medicine.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply

Reporting: Hospira, Inc., a Pfizer Company

Deferiprone Tablet (Ferriprox) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 3 other companies list it 334 days 1 NDC Hematology First posted Nov 7, 2025 Updated Nov 7, 2025

Chiesi USA is stopping production of Ferriprox (deferiprone) tablets, and this change may be permanent. Other makers — including Hikma, Sun Pharmaceutical, and Dr. Reddy's — still list deferiprone tablets in 500 mg and 1000 mg strengths.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 3 other companies listing it

Reporting: Chiesi USA, Inc.

Epinephrine Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 3 other companies list it 334 days 2 NDCs Cardiovascular, Endocrinology/Metaboli... First posted Nov 7, 2025 Updated Nov 7, 2025

Pfizer (Hospira) is permanently stopping its epinephrine injection 0.1 mg/mL. The same strength is still listed as available from other manufacturers.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 3 other companies listing it

Reporting: Hospira, Inc., a Pfizer Company

Ketamine Hydrochloride Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 7 other companies list it 334 days 1 NDC Anesthesia First posted Nov 7, 2025 Updated Nov 7, 2025

Pfizer is permanently stopping its Novaplus-branded ketamine hydrochloride injection (500 mg/5 mL vials). The same medicine at both 50 mg/mL and 100 mg/mL strengths is still listed as available from other manufacturers.

Supply risk: Low · 1/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 7 other companies listing it

Reporting: Pfizer Inc.

Everolimus Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 9 other companies list it 338 days 11 NDCs 3 companies reporting Transplant First posted Nov 3, 2025 Updated Mar 2, 2026

Three makers — Endo Pharmaceuticals, Teva, and Mylan — are permanently stopping everolimus tablets. Other manufacturers not reporting a shortage still list everolimus tablets in 2.5 mg, 5 mg, 7.5 mg, and 10 mg strengths.

Supply risk: Low · 0/5 risk factors 6/6 strengths still listed 0/3 reporting makers with supply 9 other companies listing it Medicaid use (2026): ~487 Rx

Reporting: Endo Pharmaceuticals, Inc., Mylan Pharmaceuticals Inc., a Viatris Company, Teva Pharmaceuticals USA, Inc.

Acetaminophen; Oxycodone Hydrochloride Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 24 other companies list it 338 days 6 NDCs Analgesia/Addiction First posted Nov 3, 2025 Updated Nov 3, 2025

Endo Pharmaceuticals is permanently stopping production of Percocet (oxycodone/acetaminophen) tablets. The same medicine in multiple strengths is still listed by other manufacturers, including SpecGx, Major Pharmaceuticals, KVK-Tech, and Aurolife Pharma.

Supply risk: Low · 1/5 risk factors 2/4 strengths still listed 0/1 reporting maker with supply 24 other companies listing it Medicaid use (2026): ~6,258 Rx

Reporting: Endo Pharmaceuticals, Inc.

Atazanavir Sulfate; Cobicistat Tablet (Evotaz) View full page → To Be Discontinued ⚠ Supply risk: High 338 days 1 NDC Antiviral First posted Nov 3, 2025 Updated Nov 3, 2025

Bristol Myers Squibb is stopping Evotaz (atazanavir/cobicistat) tablets, and this change is expected to be permanent. No other maker of this medicine has been found, so it may not be available from any source after the discontinuation takes effect.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply Medicaid use (2026): ~1,306 Rx

Reporting: Bristol Myers Squibb Co.

Lasmiditan Succinate Tablet (Reyvow) View full page → To Be Discontinued ⚠ Supply risk: High 338 days 6 NDCs Neurology First posted Nov 3, 2025 Updated Nov 3, 2025

Eli Lilly is stopping production of Reyvow (lasmiditan) tablets 50 mg and 100 mg, and distribution will end May 31, 2026. No other manufacturers make this medicine, so both strengths will have no listed source after that date.

Supply risk: High · 5/5 risk factors 0/2 strengths still listed 0/1 reporting maker with supply Medicaid use (2026): ~5,486 Rx

Reporting: Eli Lilly and Co.

Scopolamine Patch View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 7 other companies list it 338 days 1 NDC Gastroenterology, Neurology, Other First posted Nov 3, 2025 Updated Nov 3, 2025

Padagis is permanently stopping its scopolamine transdermal patch, which may remove one source of this medicine. The 1 mg patch (including Transderm Scop) is still listed as available from other manufacturers not reporting a shortage.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 7 other companies listing it Medicaid use (2026): ~5,678 Rx

Reporting: Padagis US LLC

Phenobarbital Tablet View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 13 other companies list it 341 days 8 NDCs Analgesia/Addiction, Neurology, Other First posted Oct 31, 2025 Updated Oct 31, 2025

Endo Pharmaceuticals is stopping production of phenobarbital tablets, and the change may be permanent. Other makers — including Hikma, Major Pharmaceuticals, e5 Pharma, and Trigen — still list phenobarbital tablets in 15 mg, 30 mg, 60 mg, and 100 mg strengths.

Supply risk: Low · 0/5 risk factors 4/4 strengths still listed 0/1 reporting maker with supply 13 other companies listing it Medicaid use (2026): ~13,378 Rx

Reporting: Endo Pharmaceuticals, Inc.

Moxifloxacin Injection View full page → To Be Discontinued ⚠ Supply risk: High 343 days 1 NDC Anti-Infective First posted Oct 29, 2025 Updated Oct 29, 2025

Fresenius Kabi is stopping production of moxifloxacin injection 400 mg/250 mL, and this change may be permanent. The same strength is still listed by Fresenius Kabi outside the shortage report, but no manufacturer currently shows an available supply.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply

Reporting: Fresenius Kabi USA, LLC

Pramlintide Acetate Injection (SymlinPen 120, SymlinPen 60) View full page → To Be Discontinued ⚠ Supply risk: High 345 days 2 NDCs Endocrinology/Metabolism First posted Oct 27, 2025 Updated Oct 27, 2025

AstraZeneca is stopping production of Symlin (pramlintide acetate) injection, and this change may be permanent. No other manufacturers are listed as a source for this medicine right now.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply Medicaid use (2026): ~39 Rx

Reporting: AstraZeneca AB

Insulin Lispro Injection (Humalog) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 2 other companies list it 348 days 2 NDCs Endocrinology/Metabolism First posted Oct 24, 2025 Updated Sep 1, 2026

Eli Lilly is discontinuing Humalog (insulin lispro) injection, and this change may be permanent, with distribution expected to end June 2027. Admelog, another insulin lispro 100 U/mL injection, is still listed by other manufacturers as available.

Supply risk: Low · 1/5 risk factors 0/1 strength / size still listed 0/1 reporting maker with supply 2 other companies listing it Medicaid use (2026): ~100,167 Rx

Reporting: Eli Lilly and Co.

Busulfan Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 5 other companies list it 348 days 1 NDC Hematology First posted Oct 24, 2025 Updated Oct 24, 2025

Viatris is permanently stopping its busulfan injection. The 6 mg/mL injection is still listed as available from other manufacturers that have not reported a shortage.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 5 other companies listing it

Reporting: Mylan Institutional, a Viatris Company

Insulin Glargine Injection (Basaglar) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 2 other companies list it 348 days 1 NDC Endocrinology/Metabolism First posted Oct 24, 2025 Updated Oct 24, 2025

Eli Lilly is stopping Basaglar (insulin glargine) injection, and this change may be permanent. Other insulin glargine products — including Lantus and Toujeo — are still listed as available from manufacturers that have not reported a shortage.

Supply risk: Low · 0/5 risk factors 0/1 reporting maker with supply 2 other companies listing it Medicaid use (2026): ~1,402 Rx

Reporting: Eli Lilly and Co.

Insulin Lispro-aabc Injection (Lyumjev) View full page → To Be Discontinued ⚠ Supply risk: High 348 days 2 NDCs Endocrinology/Metabolism First posted Oct 24, 2025 Updated Oct 24, 2025

Eli Lilly is permanently discontinuing Lyumjev (insulin lispro-aabc) injection. No other manufacturer makes this medicine, so it will not be available from any source once supplies run out.

Supply risk: High · 4/5 risk factors 0/1 reporting maker with supply Medicaid use (2026): ~27 Rx

Reporting: Eli Lilly and Co.

Tranylcypromine Sulfate Tablet (Parnate) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 4 other companies list it 351 days 1 NDC Psychiatry First posted Oct 21, 2025 Updated Oct 21, 2025

Teva is stopping its tranylcypromine sulfate 10 mg tablets, with supplies expected to run out by the end of 2025. Other makers — including the brand Parnate — still list this medicine as available.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 4 other companies listing it

Reporting: Teva Pharmaceuticals USA, Inc.

Oxaliplatin Injection View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 10 other companies list it 352 days 6 NDCs 3 companies reporting Oncology First posted Oct 20, 2025 Updated Jun 29, 2026

Three manufacturers — Sandoz, Sagent Pharmaceuticals, and Fresenius Kabi — are permanently stopping production of oxaliplatin injection. The 5 mg/mL strength is still listed by other makers, including Accord Healthcare, Baxter Healthcare, Eugia US, and Apotex.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/3 reporting makers with supply 10 other companies listing it Medicaid use (2026): ~5,584 Rx

Reporting: Fresenius Kabi USA, LLC, Jiangsu Hengrui Pharmaceuticals Co., Ltd., Sandoz Inc.

Elbasvir; Grazoprevir Tablet (Zepatier) View full page → To Be Discontinued ⚠ Supply risk: High 355 days 1 NDC Antiviral First posted Oct 17, 2025 Updated Oct 17, 2025

Merck Sharp & Dohme is stopping Zepatier (elbasvir/grazoprevir) tablets, and the change is permanent as of December 1, 2025. No other manufacturer makes this medicine, so it will not be available from any source after that date.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply

Reporting: Merck Sharp & Dohme LLC

Vigabatrin Oral Solution (Vigpoder) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 8 other companies list it 356 days 1 NDC Neurology First posted Oct 16, 2025 Updated Oct 16, 2025

Pyros Pharmaceuticals is stopping production of vigabatrin oral solution, and this change may be permanent. Other makers have not reported a shortage and still list vigabatrin oral solution (powder for solution) at the same strength.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 8 other companies listing it

Reporting: Pyros Pharmaceuticals, Inc.

Voriconazole Injection (Vfend) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 9 other companies list it 356 days 1 NDC Antiviral First posted Oct 16, 2025 Updated Oct 16, 2025

Pfizer is permanently stopping production of voriconazole injection (10 mg/mL). The same medicine — including Vfend (voriconazole) injection — is still listed as available from other manufacturers.

Supply risk: Low · 0/5 risk factors 1/1 strength still listed 0/1 reporting maker with supply 9 other companies listing it

Reporting: Pfizer Inc.

Pemetrexed Disodium Injection (Alimta) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 13 other companies list it 362 days 4 NDCs 2 companies reporting Oncology First posted Oct 10, 2025 Updated Oct 16, 2025

Eli Lilly and Sandoz are permanently stopping all forms of Alimta (pemetrexed disodium) injection. Generic pemetrexed in multiple strengths is still listed as available from other manufacturers, including Hospira, Accord Healthcare, Sagent Pharmaceuticals, and Solco Healthcare.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/2 reporting makers with supply 13 other companies listing it Medicaid use (2026): ~818 Rx

Reporting: Eli Lilly and Co., Sandoz Inc.

Adalimumab-afzb Injection (Abrilada) View full page → To Be Discontinued ⚠ Supply risk: High 363 days 1 NDC Rheumatology First posted Oct 9, 2025 Updated Oct 9, 2025

Pfizer is stopping production of Abrilada (adalimumab-afzb) injection, and this change may be permanent. No other manufacturer of this same medicine has supply listed at this time.

Supply risk: High · 4/5 risk factors 0/1 reporting maker with supply

Reporting: Pfizer Inc.

Omeprazole Delayed-Release Capsule View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 25 other companies list it 363 days 10 NDCs Gastroenterology First posted Oct 9, 2025 Updated Oct 9, 2025

Sandoz is permanently stopping its omeprazole delayed-release capsules. Other makers — including Major Pharmaceuticals and NorthStar Rx — still list 10 mg, 20 mg, and 40 mg omeprazole capsules as available.

Supply risk: Low · 0/5 risk factors 3/3 strengths still listed 0/1 reporting maker with supply 25 other companies listing it Medicaid use (2026): ~125,474 Rx

Reporting: Sandoz Inc.

Cobicistat Tablet (Tybost) View full page → To Be Discontinued ⚠ Supply risk: High 365 days · 1.0 yr 1 NDC Antiviral First posted Oct 7, 2025 Updated Oct 7, 2025

Tybost (cobicistat) tablets are being discontinued by Gilead Sciences for business reasons, and the change is permanent. No other manufacturer makes this medicine, so it will not be available once current supplies sell through at the end of February 2026.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply Medicaid use (2026): ~42 Rx

Reporting: Gilead Sciences, Inc.

Paricalcitol Capsule (Zemplar) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 4 other companies list it 365 days · 1.0 yr 2 NDCs Endocrinology/Metabolism First posted Oct 7, 2025 Updated Oct 7, 2025

AbbVie is permanently stopping production of Zemplar (paricalcitol) capsules. Generic paricalcitol capsules in 1 mcg and 2 mcg strengths are still listed as available from other manufacturers who have not reported a shortage.

Supply risk: Low · 0/5 risk factors 2/2 strengths still listed 0/1 reporting maker with supply 4 other companies listing it Medicaid use (2025): ~18 Rx

Reporting: AbbVie Inc.

Meperidine Hydrochloride Injection (Demerol) View full page → Current ⚠ Supply risk: Low 495 days · 1.4 yr 6 NDCs 2 companies reporting Analgesia/Addiction First posted May 30, 2025 Updated Sep 22, 2026

Meperidine hydrochloride injection has been on the FDA shortage list for over a year, though all strengths — 25 mg/mL, 50 mg/mL, and 100 mg/mL — still have available sources. Demerol (meperidine hydrochloride) 75 mg/mL injection is also listed by Hospira, which has not reported a shortage.

Supply risk: Low · 2/5 risk factors 3/3 strengths still listed 2/2 reporting makers with supply 0% of NDCs unavailable Medicaid use (2026): ~4,642 Rx

Reporting: Hikma Pharmaceuticals USA, Inc., Hospira, Inc., a Pfizer Company

Bacitracin Ophthalmic Ointment View full page → Current ⚠ Supply risk: High 583 days · 1.6 yr 1 NDC Anti-Infective, Ophthalmology First posted Mar 3, 2025 Updated Jun 1, 2026

Bacitracin ophthalmic ointment is being discontinued by Padagis, and this change may be permanent. No other manufacturer is currently listed as a source for this product.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 100% of NDCs unavailable

Why: Discontinuation of the manufacture of the drug

Reporting: Padagis US LLC

Methylphenidate Extended-Release Film View full page → Current ⚠ Supply risk: Low ✓ 1 other company lists it 586 days · 1.6 yr 4 NDCs Psychiatry First posted Feb 28, 2025 Updated Sep 2, 2026

Methylphenidate extended-release film tablets are listed as in shortage, though all strengths (10 mg, 15 mg, 20 mg, and 30 mg) still have at least one available source. Methylphenidate patches are listed by makers not reporting a shortage.

Supply risk: Low · 2/5 risk factors 4/4 strengths still listed 1/1 reporting maker with supply 1 other company listing it 0% of NDCs unavailable Medicaid use (2026): ~3,574 Rx

Reporting: Noven Pharmaceuticals, Inc.

Hydroxocobalamin Injection (Cyanokit) View full page → Current ⚠ Supply risk: High 702 days · 1.9 yr 2 NDCs 2 companies reporting Other First posted Nov 4, 2024 Updated Oct 1, 2026

Generic hydroxocobalamin injection is unavailable from the one maker reporting a shortage, while Cyanokit (hydroxocobalamin) 5 g/250 mL injection remains available to order. The 30 mL multi-dose vial currently has no listed source from any reporting manufacturer.

Supply risk: High · 5/5 risk factors 1/2 strengths still listed 1/2 reporting makers with supply 50% of NDCs unavailable Medicaid use (2026): ~804 Rx

Why: Other

Reporting: BTG International Inc., Teva Pharmaceuticals USA, Inc.

Dextrose Monohydrate 70% Injection View full page → Current ⚠ Supply risk: Low 726 days · 2.0 yr 4 NDCs 3 companies reporting Endocrinology/Metabolism, Gastroentero... First posted Oct 11, 2024 Updated Oct 2, 2026

Dextrose Monohydrate 70% Injection has been in shortage for over a year, though all three manufacturers reporting the shortage still list some supply available. The 70 g/100 mL strength remains sourced, but Baxter Healthcare does not expect full recovery until September 2026.

Supply risk: Low · 1/5 risk factors 1/1 strength still listed 3/3 reporting makers with supply 0% of NDCs unavailable Medicaid use (2025): ~56,958 Rx

Why: Other

Reporting: B. Braun Medical Inc., Baxter Healthcare, Otsuka ICU Medical LLC

Riluzole Oral Suspension (Teglutik, Tiglutik) View full page → Current ⚠ Supply risk: High 985 days · 2.7 yr 4 NDCs Neurology First posted Jan 26, 2024 Updated Oct 1, 2026

Tiglutik / Teglutik (riluzole) oral suspension has been in shortage for over a year due to manufacturing compliance issues. The 5 mg/1 mL strength still has supply from the one reporting manufacturer, but the 50 mg/10 mL strength currently has no listed source.

Supply risk: High · 4/5 risk factors 1/2 strengths still listed 1/1 reporting maker with supply 25% of NDCs unavailable

Why: Requirements related to complying with good manufacturing practices

Reporting: EDW Pharma, Inc. (formerly Italfarmaco Pharma, Inc.)

Technetium Tc-99M Pyrophosphate Injection (CIS-PYRO, Technescan PYP) View full page → Current ⚠ Supply risk: High 1,015 days · 2.8 yr 3 NDCs 2 companies reporting Medical Imaging First posted Dec 27, 2023 Updated Oct 1, 2026

Technetium Tc-99m pyrophosphate kit injection is in shortage, mainly due to an active ingredient supply problem that has lasted over a year. The 12 mg/10 mL strength has no available source right now; the 11.9 mg and 3.2 mg strengths remain on allocation from one of the two manufacturers.

Supply risk: High · 5/5 risk factors 1/2 strengths still listed 1/2 reporting makers with supply 67% of NDCs unavailable

Why: Other; Shortage of an active ingredient

Reporting: Curium US LLC, Sun Pharmaceutical Industries, Inc.

Promethazine Hydrochloride Injection (Phenergan) View full page → Current ⚠ Supply risk: Medium 1,051 days · 2.9 yr 10 NDCs 2 companies reporting Analgesia/Addiction, Gastroenterology,... First posted Nov 21, 2023 Updated Sep 22, 2026

Promethazine hydrochloride injection has been on the FDA shortage list for over a year due to increased demand. Both available strengths (25 mg/mL and 50 mg/mL) still have listed supply from reporting manufacturers, though availability is limited and fuller recovery is not expected until around October 2026.

Supply risk: Medium · 3/5 risk factors 2/2 strengths still listed 2/2 reporting makers with supply 60% of NDCs unavailable Medicaid use (2026): ~35,015 Rx

Why: Demand increase for the drug; Other

Reporting: Hikma Pharmaceuticals USA, Inc., XGen Pharmaceuticals DJB, Inc.

Cromolyn Sodium Concentrate (Gastrocrom) View full page → Current ⚠ Supply risk: Low 1,069 days · 2.9 yr 6 NDCs 4 companies reporting Pulmonary/Allergy First posted Nov 3, 2023 Updated Oct 5, 2026

Generic cromolyn sodium concentrate is in short supply, with some versions limited — but Gastrocrom (the brand) remains available, and all reporting manufacturers still list at least some supply of the 20 mg/mL and 100 mg/5 mL strengths.

Supply risk: Low · 1/5 risk factors 2/2 strengths still listed 4/4 reporting makers with supply 0% of NDCs unavailable Medicaid use (2026): ~18,392 Rx

Why: Other

Reporting: Ailex Pharmaceuticals, Micro Labs LTD, Mylan Specialty, a Viatris Company, Rising Pharma Holdings, Inc.

Propranolol Hydrochloride Injection View full page → Current ⚠ Supply risk: High 1,072 days · 2.9 yr 2 NDCs 2 companies reporting Cardiovascular First posted Oct 31, 2023 Updated Sep 18, 2026

Propranolol injection is in shortage due to a lack of active ingredient, and has been for over a year. One of two makers still lists supply available — check wholesalers for current stock.

Supply risk: High · 4/5 risk factors 1/1 strength still listed 1/2 reporting makers with supply 50% of NDCs unavailable

Why: Shortage of an active ingredient

Reporting: Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc.

Methylphenidate Hydrochloride Extended-Release Tablet (Relexxii, Concerta) View full page → Current ⚠ Supply risk: Low ✓ 18 other companies list it 1,169 days · 3.2 yr 34 NDCs 6 companies reporting Psychiatry First posted Jul 26, 2023 Updated Oct 1, 2026

Methylphenidate extended-release tablets have been in shortage for over a year. Most strengths still have at least one supplier, and some makers not reporting a shortage list this medicine.

Supply risk: Low · 1/5 risk factors 7/7 strengths still listed 5/6 reporting makers with supply 18 other companies listing it 18% of NDCs unavailable Medicaid use (2026): ~2,430,423 Rx

Why: Demand increase for the drug; Other; Discontinuation of the manufacture of the drug

Reporting: Janssen Pharmaceuticals, Lannett Company, Inc., Sun Pharmaceutical Industries, Inc., Teva Pharmaceuticals USA, Inc. and 2 more

Liraglutide Injection (Saxenda, Victoza) View full page → Current ⚠ Supply risk: Low ✓ 5 other companies list it 1,177 days · 3.2 yr 11 NDCs 4 companies reporting Endocrinology/Metabolism First posted Jul 18, 2023 Updated Sep 22, 2026

Victoza and Saxenda (liraglutide) injections are in short supply, with some versions being discontinued, though Victoza's supply remains mostly available and the 6 mg/mL strength is still listed by several other manufacturers not reporting a shortage.

Supply risk: Low · 1/5 risk factors 1/1 strength still listed 3/4 reporting makers with supply 5 other companies listing it 0% of NDCs unavailable Medicaid use (2026): ~225,289 Rx

Why: Delay in shipping of the drug; Discontinuation of the manufacture of the drug

Reporting: Hikma Pharmaceuticals USA, Inc., Meitheal Pharmaceuticals, Inc., Novo Nordisk, Inc., Teva Pharmaceuticals USA, Inc.

Lisdexamfetamine Dimesylate Capsule (Vyvanse) View full page → Current ⚠ Supply risk: Low ✓ 6 other companies list it 1,181 days · 3.2 yr 90 NDCs 13 companies reporting Psychiatry First posted Jul 14, 2023 Updated Oct 5, 2026

Generic Vyvanse (lisdexamfetamine) capsules are in shortage, with about 40% of generic products unavailable or limited — though Vyvanse brand capsules themselves are fully available. Generic versions at all strengths are still listed by some manufacturers not reporting a shortage, including Sandoz, Camber Pharmaceuticals, AvKARE, and American Health Packaging.

Supply risk: Low · 1/5 risk factors 7/7 strengths still listed 13/13 reporting makers with supply 6 other companies listing it 1% of NDCs unavailable Medicaid use (2026): ~3,631,357 Rx

Why: Shortage of an active ingredient; Other; Delay in shipping of the drug

Reporting: Alvogen, Amneal Pharmaceuticals, Apotex Corp., Elite Laboratories, Inc. and 9 more

Lisdexamfetamine Dimesylate Chewable Tablet (Vyvanse) View full page → Current ⚠ Supply risk: Low ✓ 4 other companies list it 1,181 days · 3.2 yr 18 NDCs 3 companies reporting Psychiatry First posted Jul 14, 2023 Updated Sep 18, 2026

Vyvanse (lisdexamfetamine) chewable tablets are on the FDA shortage list, but the brand-name Vyvanse chewable tablets show all products available — the shortage is mainly among generic versions. Generic lisdexamfetamine chewable tablets are still listed by makers not reporting a shortage, including SpecGx, Teva, Camber, and Granules Pharmaceuticals.

Supply risk: Low · 1/5 risk factors 6/6 strengths still listed 3/3 reporting makers with supply 4 other companies listing it 0% of NDCs unavailable Medicaid use (2026): ~180,842 Rx

Reporting: Novadoz Pharmaceuticals LLC, Sun Pharmaceutical Industries, Inc., Takeda Pharmaceuticals USA Inc.

Carboplatin Injection (Kyxata) View full page → Current ⚠ Supply risk: Medium 1,258 days · 3.4 yr 35 NDCs 9 companies reporting Oncology First posted Apr 28, 2023 Updated Oct 3, 2026

Carboplatin injection is in a nationwide shortage that has lasted over a year, with several vial sizes currently having no available source. Some strengths remain available from makers not reporting a shortage, including 450 mg/45 mL and 600 mg/60 mL sizes.

Supply risk: Medium · 3/5 risk factors 11/16 strengths still listed 5/9 reporting makers with supply 55% of NDCs unavailable Medicaid use (2026): ~35,737 Rx

Why: Other; Discontinuation of the manufacture of the drug; Demand increase for the drug

Reporting: Accord Healthcare Inc., Avyxa Pharma, LLC, Eugia US LLC, Fresenius Kabi USA, LLC and 5 more

Sterile Water Irrigation Solution View full page → Current ⚠ Supply risk: Low ✓ 1 other company lists it 1,258 days · 3.4 yr 9 NDCs 3 companies reporting Gastroenterology, Other, Pediatric First posted Apr 28, 2023 Updated Oct 2, 2026

Sterile Water Irrigant is currently in shortage, driven by manufacturing discontinuations and rising demand. Most strengths still have supply from other makers, including B. Braun Medical and ICU Medical.

Supply risk: Low · 1/5 risk factors 2/2 sizes still listed 2/3 reporting makers with supply 1 other company listing it 44% of NDCs unavailable Medicaid use (2025): ~75,431 Rx

Why: Discontinuation of the manufacture of the drug; Other

Reporting: B. Braun Medical Inc., Baxter Healthcare, Otsuka ICU Medical LLC

Prazosin Hydrochloride Capsule (Minipress) View full page → To Be Discontinued ⚠ Supply risk: Low ✓ 23 other companies list it 1,258 days · 3.4 yr 3 NDCs Cardiovascular First posted Apr 28, 2023 Updated Apr 28, 2023

Pfizer is permanently stopping production of prazosin hydrochloride capsules. Other makers — including Teva, Mylan, Major Pharmaceuticals, and Marlex — still list prazosin capsules in 1 mg, 2 mg, and 5 mg strengths, so the medicine may be available through other sources.

Supply risk: Low · 0/5 risk factors 3/3 strengths still listed 0/1 reporting maker with supply 23 other companies listing it

Reporting: Pfizer Inc.

Penicillin G Benzathine Injection (Bicillin L-A, Lentocilin) View full page → Current ⚠ Supply risk: Low ✓ 1 other company lists it 1,260 days · 3.5 yr 4 NDCs 2 companies reporting Anti-Infective First posted Apr 26, 2023 Updated Sep 21, 2026

Bicillin L-A (penicillin G benzathine) injection has been in shortage for over a year due to manufacturing delays. Most strengths still have some supply from reporting makers, though the 600,000 IU/mL strength has no listed source from any manufacturer right now.

Supply risk: Low · 2/5 risk factors 3/4 strengths / sizes still listed 2/2 reporting makers with supply 1 other company listing it 25% of NDCs unavailable Medicaid use (2026): ~24,817 Rx

Why: Other

Reporting: Laboratorios Atral, Pfizer Inc.

Clindamycin Phosphate Injection (Cleocin Phosphate) View full page → Current ⚠ Supply risk: Low ✓ 1 other company lists it 1,296 days · 3.6 yr 23 NDCs 4 companies reporting Anti-Infective First posted Mar 21, 2023 Updated Oct 2, 2026

Pfizer is stopping production of Cleocin Phosphate (clindamycin phosphate) injection, and the generic versions from other makers are in short supply, though most reporting manufacturers still list some strengths as available. Hikma Pharmaceuticals also lists clindamycin injection products that are not part of this shortage report.

Supply risk: Low · 2/5 risk factors 9/16 strengths still listed 4/4 reporting makers with supply 1 other company listing it 24% of NDCs unavailable Medicaid use (2026): ~7,931 Rx

Why: Demand increase for the drug; Discontinuation of the manufacture of the drug

Reporting: Baxter Healthcare, Pfizer Inc., Sagent Pharmaceuticals, Sandoz Inc.

Methotrexate Sodium Injection View full page → Current ⚠ Supply risk: Low 1,304 days · 3.6 yr 14 NDCs 5 companies reporting Rheumatology, Oncology First posted Mar 13, 2023 Updated Oct 3, 2026

Methotrexate sodium injection has been in shortage for over a year, driven by rising demand. Some strengths remain available from several manufacturers, and no strengths are currently listed without any supply source.

Supply risk: Low · 1/5 risk factors 4/4 strengths still listed 3/5 reporting makers with supply 29% of NDCs unavailable Medicaid use (2026): ~63,044 Rx

Why: Other; Demand increase for the drug

Reporting: Accord Healthcare Inc., Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc., Hospira, Inc., a Pfizer Company and 1 more

Clonazepam Tablet (Klonopin) View full page → Current ⚠ Supply risk: Low ✓ 16 other companies list it 1,307 days · 3.6 yr 40 NDCs 6 companies reporting Neurology, Pediatric, Psychiatry First posted Mar 10, 2023 Updated Oct 3, 2026

Generic clonazepam tablets are in limited supply from some manufacturers, though all three Klonopin (clonazepam) brand products remain available. Generic versions are still listed by makers not reporting a shortage, including Major Pharmaceuticals and others, across all strengths (0.5 mg, 1 mg, 2 mg).

Supply risk: Low · 1/5 risk factors 3/3 strengths still listed 6/6 reporting makers with supply 16 other companies listing it 0% of NDCs unavailable Medicaid use (2026): ~3,372,787 Rx

Why: Other

Reporting: Accord Healthcare Inc., Aurobindo Pharma USA, Cheplapharm Arzneimittel GmbH, Prinston Pharmaceutical, Inc. and 2 more

Rocuronium Bromide Injection View full page → Current ⚠ Supply risk: Low ✓ 7 other companies list it 1,330 days · 3.6 yr 26 NDCs 11 companies reporting Anesthesia First posted Feb 15, 2023 Updated Oct 5, 2026

Rocuronium bromide injection has been in shortage for over a year due to shipping delays and rising demand. All strengths still have listed supply from reporting manufacturers, and additional makers not reporting a shortage also list this medicine as available.

Supply risk: Low · 1/5 risk factors 5/5 strengths still listed 11/11 reporting makers with supply 7 other companies listing it 8% of NDCs unavailable Medicaid use (2026): ~28,836 Rx

Why: Delay in shipping of the drug; Demand increase for the drug

Reporting: Baxter Healthcare, Eugia US LLC, Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc. and 7 more

Quinapril Hydrochloride Tablet View full page → Current ⚠ Supply risk: Low ✓ 3 other companies list it 1,357 days · 3.7 yr 16 NDCs 4 companies reporting Cardiovascular First posted Jan 19, 2023 Updated Oct 2, 2026

Quinapril hydrochloride tablets are in a shortage that has lasted over a year, with most manufacturers either discontinuing the drug or facing long-term backlogs with no clear restock date. Some makers not reporting a shortage — including Proficient Rx LP, BluePoint Laboratories, and Cipla USA — still list supply at multiple strengths.

Supply risk: Low · 2/5 risk factors 4/4 strengths still listed 1/4 reporting makers with supply 3 other companies listing it 75% of NDCs unavailable

Why: Discontinuation of the manufacture of the drug; Requirements related to complying with good manufacturing practices; Shortage of an active ingredient

Reporting: Aurobindo Pharma USA, Chartwell Molecular Holdings LLC, Lupin Pharmaceuticals, Inc., Solco Healthcare US, LLC

Quinapril/Hydrochlorothiazide Tablet View full page → Current ⚠ Supply risk: Low ✓ 2 other companies list it 1,357 days · 3.7 yr 6 NDCs 2 companies reporting Cardiovascular First posted Jan 19, 2023 Updated Oct 2, 2026

Aurobindo Pharma USA is stopping its quinapril/hydrochlorothiazide tablets, and this change may be permanent. The same medicine is still listed by other manufacturers, including Lupin Pharmaceuticals and Cipla USA, so supply exists from sources not reporting a shortage.

Supply risk: Low · 2/5 risk factors 3/3 strengths still listed 1/2 reporting makers with supply 2 other companies listing it 50% of NDCs unavailable

Why: Discontinuation of the manufacture of the drug

Reporting: Aurobindo Pharma USA, Chartwell Molecular Holdings LLC

Mixed Amphetamine Salts Tablet (Adderall) View full page → Current ⚠ Supply risk: Low ✓ 8 other companies list it 1,456 days · 4.0 yr 73 NDCs 11 companies reporting Psychiatry First posted Oct 12, 2022 Updated Oct 5, 2026

Mixed amphetamine salts tablets (the generic form of Adderall) have been in shortage for over a year, driven by ingredient supply problems and rising demand. Some manufacturers are not reporting a shortage, so certain strengths may still be available depending on the pharmacy's supplier.

Supply risk: Low · 1/5 risk factors 7/7 strengths still listed 8/11 reporting makers with supply 8 other companies listing it 26% of NDCs unavailable Medicaid use (2026): ~3,980,331 Rx

Why: Shortage of an active ingredient; Demand increase for the drug; Other

Reporting: Alvogen, Aurobindo Pharma USA, Elite Laboratories, Inc., Epic Pharma, LLC and 7 more

Etomidate Injection (Amidate) View full page → Current ⚠ Supply risk: Low ✓ 1 other company lists it 1,463 days · 4.0 yr 18 NDCs 6 companies reporting Anesthesia First posted Oct 5, 2022 Updated Oct 5, 2026

Most versions of Amidate (etomidate) injection are still available, but this shortage — ongoing for over a year — is mostly affecting generic products, with 2 of 16 generic versions unavailable; the Amidate brand itself has 1 of 2 products available. The 2 mg/mL and 2 mg/1 mL strengths still have listed sources, though the 20 mg/10 mL and 40 mg/20 mL sizes currently have none.

Supply risk: Low · 1/5 risk factors 3/3 strengths still listed 5/6 reporting makers with supply 1 other company listing it 17% of NDCs unavailable Medicaid use (2025): ~818 Rx

Why: Demand increase for the drug; Other

Reporting: Caplin Steriles, Ltd., Eugia US LLC, Gland Pharma Limited, Hikma Pharmaceuticals USA, Inc. and 2 more

Flurazepam Hydrochloride Capsule View full page → Current ⚠ Supply risk: Medium 1,526 days · 4.2 yr 6 NDCs 2 companies reporting Neurology, Other First posted Aug 3, 2022 Updated Sep 15, 2026

Flurazepam hydrochloride capsules are in shortage due to a manufacturing delay, with one of two reporting makers still listing supply in both the 15 mg and 30 mg strengths. Rising Pharma does not expect its supply to return until late 2026, so availability may be limited depending on which manufacturer your pharmacy sources from.

Supply risk: Medium · 3/5 risk factors 2/2 strengths still listed 1/2 reporting makers with supply 33% of NDCs unavailable

Why: Regulatory delay

Reporting: Chartwell Molecular Holdings LLC, Rising Pharma Holdings, Inc.

Streptozocin Powder for Solution (Zanosar) View full page → Current ⚠ Supply risk: High 1,548 days · 4.2 yr 2 NDCs 2 companies reporting Oncology First posted Jul 12, 2022 Updated Oct 1, 2026

Streptozocin powder for solution is currently in shortage, with the 100 mg/1 mL concentration having no available source right now. The 1 g/10 mL strength still has a listed supply from one manufacturer.

Supply risk: High · 5/5 risk factors 1/2 strengths still listed 1/2 reporting makers with supply 50% of NDCs unavailable

Why: Other

Reporting: ESTEVE PHARMACEUTICALS, S.A., Teva Pharmaceuticals USA, Inc.

Remifentanil Hydrochloride Injection (Ultiva) View full page → Current ⚠ Supply risk: Low 1,562 days · 4.3 yr 9 NDCs 3 companies reporting Analgesia/Addiction First posted Jun 28, 2022 Updated Oct 5, 2026

The shortage of Ultiva (remifentanil) is mostly in the generic versions — specifically the 1 mg per vial and 2 mg per vial strengths, which currently have no listed source. All three Ultiva brand products remain available, though this shortage has lasted over a year.

Supply risk: Low · 2/5 risk factors 4/6 strengths still listed 3/3 reporting makers with supply 33% of NDCs unavailable Medicaid use (2026): ~837 Rx

Why: Demand increase for the drug; Delay in shipping of the drug

Reporting: Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc., Mylan Institutional, a Viatris Company

Sufentanil Citrate Injection View full page → Current ⚠ Supply risk: High 1,618 days · 4.4 yr 4 NDCs 2 companies reporting Analgesia/Addiction, Pediatric First posted May 3, 2022 Updated Sep 22, 2026

Sufentanil citrate injection is in shortage, and Hikma is not currently making it. One of the two manufacturers still lists some supply, but not all strengths are available, and no other makers are on record as an alternative source.

Supply risk: High · 5/5 risk factors 1/2 strengths still listed 1/2 reporting makers with supply 75% of NDCs unavailable Medicaid use (2026): ~74 Rx

Why: Other

Reporting: Hikma Pharmaceuticals USA, Inc., Hospira, Inc., a Pfizer Company

Conivaptan Hydrochloride Injection (Vaprisol Dextrose In Plastic Container) View full page → Current ⚠ Supply risk: High 1,668 days · 4.6 yr 1 NDC Cardiovascular First posted Mar 14, 2022 Updated Sep 16, 2026

Vaprisol Dextrose In Plastic Container (conivaptan hydrochloride) injection 20 mg/100 mL has been in shortage for over a year due to shipping delays, with no recovery date set. No other makers of this medicine are currently listed as an alternative source.

Supply risk: High · 5/5 risk factors 0/1 strength still listed 0/1 reporting maker with supply 100% of NDCs unavailable

Why: Delay in shipping of the drug

Reporting: Cumberland Pharmaceuticals Inc.

Dextrose Monohydrate 10% Injection View full page → Current ⚠ Supply risk: Low ✓ 1 other company lists it 1,681 days · 4.6 yr 13 NDCs 4 companies reporting Endocrinology/Metabolism, Gastroentero... First posted Mar 1, 2022 Updated Oct 2, 2026

Dextrose Monohydrate 10% Injection has been on the shortage list for over a year, with at least one maker stopping production. All four reporting manufacturers still list some supply available, and Becton Dickinson also lists the 100 mg/mL strength without reporting a shortage.

Supply risk: Low · 1/5 risk factors 3/3 strengths still listed 4/4 reporting makers with supply 1 other company listing it 8% of NDCs unavailable Medicaid use (2026): ~1,429 Rx

Why: Discontinuation of the manufacture of the drug

Reporting: B. Braun Medical Inc., Baxter Healthcare, Fresenius Kabi USA, LLC, Otsuka ICU Medical LLC

Dextrose Monohydrate 5% Injection View full page → Current ⚠ Supply risk: Low ✓ 3 other companies list it 1,696 days · 4.6 yr 36 NDCs 4 companies reporting Endocrinology/Metabolism, Gastroentero... First posted Feb 14, 2022 Updated Oct 2, 2026

Dextrose 5% IV solution (dextrose monohydrate injection) has been in shortage for over a year due to high demand, though all four reporting manufacturers still list some supply available. The same product is also listed by Baxter, B. Braun, and Hospira, which have not reported a shortage — check with wholesalers for current inventory.

Supply risk: Low · 1/5 risk factors 4/4 strengths still listed 4/4 reporting makers with supply 3 other companies listing it 6% of NDCs unavailable Medicaid use (2026): ~81,407 Rx

Why: Demand increase for the drug; Other

Reporting: B. Braun Medical Inc., Baxter Healthcare, Fresenius Kabi USA, LLC, Otsuka ICU Medical LLC

Metronidazole Injection (Flagyl I.v. Rtu In Plastic Container) View full page → Current ⚠ Supply risk: Low ✓ 3 other companies list it 1,728 days · 4.7 yr 4 NDCs 3 companies reporting Anti-Infective First posted Jan 13, 2022 Updated Oct 2, 2026

Gland Pharma is permanently stopping its metronidazole injection. The 500 mg/100 mL strength is still listed by other makers who have not reported a shortage.

Supply risk: Low · 1/5 risk factors 1/1 strength still listed 2/3 reporting makers with supply 3 other companies listing it 25% of NDCs unavailable Medicaid use (2026): ~21,299 Rx

Why: Other; Discontinuation of the manufacture of the drug

Reporting: Baxter Healthcare, Gland Pharma Limited, InfoRLife SA

Dextrose Monohydrate 50% Injection View full page → Current ⚠ Supply risk: Low ✓ 2 other companies list it 1,728 days · 4.7 yr 4 NDCs 2 companies reporting Endocrinology/Metabolism, Gastroentero... First posted Jan 13, 2022 Updated Sep 22, 2026

Dextrose 50% injection (dextrose monohydrate) is in a lasting shortage, with one strength — the 0.5 g/mL ABBOJECT® glass syringe — having no available source from reporting makers. Other strengths, including 25 g/50 mL, are still listed by ICU Medical and RemedyRepack.

Supply risk: Low · 2/5 risk factors 1/2 strengths still listed 2/2 reporting makers with supply 2 other companies listing it 0% of NDCs unavailable Medicaid use (2025): ~3,521 Rx

Why: Other

Reporting: Amphastar Pharmaceuticals, Inc., Hospira, Inc., a Pfizer Company

Rifampin Capsule View full page → Current ⚠ Supply risk: Low ✓ 5 other companies list it 1,750 days · 4.8 yr 9 NDCs 2 companies reporting Anti-Infective First posted Dec 22, 2021 Updated Oct 5, 2026

Epic Pharma is stopping production of rifampin capsules, and that change may be permanent. Both the 150 mg and 300 mg capsules are still listed by other makers that have not reported a shortage.

Supply risk: Low · 1/5 risk factors 2/2 strengths still listed 2/2 reporting makers with supply 5 other companies listing it 44% of NDCs unavailable Medicaid use (2026): ~73,786 Rx

Why: Discontinuation of the manufacture of the drug

Reporting: Epic Pharma, LLC, Lupin Pharmaceuticals, Inc.

Methylprednisolone Acetate Injection (Depo-medrol) View full page → Current ⚠ Supply risk: Low ✓ 3 other companies list it 1,757 days · 4.8 yr 23 NDCs 5 companies reporting Rheumatology First posted Dec 15, 2021 Updated Oct 2, 2026

Methylprednisolone acetate injection has been in short supply for over a year, driven by manufacturing delays, ingredient shortages, and rising demand. Other makers not reporting a shortage still list this medicine, so supply may be available from other sources.

Supply risk: Low · 1/5 risk factors 3/3 strengths still listed 3/5 reporting makers with supply 3 other companies listing it 30% of NDCs unavailable Medicaid use (2026): ~480,388 Rx

Why: Other; Demand increase for the drug; Shortage of an active ingredient

Reporting: Amneal Pharmaceuticals, Eugia US LLC, Par Health, USA LLC, Pfizer Inc. and 1 more

Sterile Water Injection (Bacteriostatic Water For Injection In Plastic Container) View full page → Current ⚠ Supply risk: Low ✓ 10 other companies list it 1,779 days · 4.9 yr 12 NDCs 5 companies reporting Other First posted Nov 23, 2021 Updated Sep 22, 2026

Sterile Water Injection has been in shortage for over a year due to high demand. Some supply is still available from makers not reporting a shortage, including B. Braun Medical, Baxter Healthcare, Hospira, and American Regent.

Supply risk: Low · 1/5 risk factors 3/3 sizes still listed 5/5 reporting makers with supply 10 other companies listing it 8% of NDCs unavailable Medicaid use (2026): ~35,586 Rx

Why: Demand increase for the drug; Other

Reporting: Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc., Hospira, Inc., a Pfizer Company, Medefil, Inc. and 1 more

Triamcinolone Hexacetonide Injection (Hexatrione) View full page → Current ⚠ Supply risk: Medium 1,982 days · 5.4 yr 1 NDC Rheumatology First posted May 4, 2021 Updated Sep 15, 2026

Triamcinolone hexacetonide injection is currently in shortage, though the 40 mg/2 mL strength still has at least one maker reporting supply. No other manufacturers are tracked for this medicine, so availability may be limited.

Supply risk: Medium · 3/5 risk factors 1/1 strength still listed 1/1 reporting maker with supply 0% of NDCs unavailable

Reporting: Medexus

Desmopressin Acetate Spray (Ddavp, Stimate) View full page → Current ⚠ Supply risk: High 2,035 days · 5.6 yr 4 NDCs 2 companies reporting Hematology First posted Mar 12, 2021 Updated Sep 16, 2026

Desmopressin acetate nasal spray is in shortage, with most strengths currently unavailable from any manufacturer. The 10 mcg strength still has one supplier, but the .1 mcg/mL, 10 mcg/.1 mL, and 1.5 mg/mL strengths have no available source right now.

Supply risk: High · 5/5 risk factors 1/4 strengths still listed 1/2 reporting makers with supply 75% of NDCs unavailable Medicaid use (2026): ~12,192 Rx

Why: Requirements related to complying with good manufacturing practices

Reporting: Apotex Corp., Ferring

Rifampin Injection (Rifadin) View full page → Current ⚠ Supply risk: High 2,058 days · 5.6 yr 4 NDCs 3 companies reporting Anti-Infective First posted Feb 17, 2021 Updated Oct 5, 2026

Rifadin (rifampin) injection is in a lasting shortage, driven mainly by generic supply problems — the brand's maker, Sanofi-Aventis, is permanently discontinuing it, while generic versions remain mostly unavailable. The 600 mg vial has one limited source, but the 600 mg/10 mL concentration has no listed supply from any reporting manufacturer.

Supply risk: High · 4/5 risk factors 1/2 strengths still listed 1/3 reporting makers with supply 67% of NDCs unavailable Medicaid use (2025): ~64 Rx

Why: Demand increase for the drug; Discontinuation of the manufacture of the drug; Other

Reporting: Fresenius Kabi USA, LLC, Mylan Institutional, a Viatris Company, Sanofi-Aventis U.S. LLC

Valproate Sodium Injection View full page → Current ⚠ Supply risk: Low ✓ 1 other company lists it 2,107 days · 5.8 yr 2 NDCs 2 companies reporting Neurology First posted Dec 30, 2020 Updated Sep 18, 2026

Valproate sodium injection has been on the FDA shortage list for over a year, but both strengths — 500 mg/5 mL and 100 mg/mL — still have available supply. The same medicine is also listed by makers not reporting a shortage, including Hikma and Sagent Pharmaceuticals.

Supply risk: Low · 1/5 risk factors 2/2 strengths still listed 2/2 reporting makers with supply 1 other company listing it 0% of NDCs unavailable Medicaid use (2026): ~410 Rx

Reporting: Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc.

Azacitidine Injection (Vidaza) View full page → Current ⚠ Supply risk: Low ✓ 8 other companies list it 2,119 days · 5.8 yr 9 NDCs 9 companies reporting Oncology First posted Dec 18, 2020 Updated Oct 3, 2026

The shortage of Vidaza (azacitidine) injection is mostly affecting generic versions — brand-name Vidaza has products available, while 4 of 8 generic products are unavailable or limited. Generic azacitidine 100 mg is still listed by manufacturers not reporting a shortage, including Sandoz, NorthStar Rx, Apotex, and BluePoint Laboratories.

Supply risk: Low · 2/5 risk factors 3/4 strengths still listed 6/9 reporting makers with supply 8 other companies listing it 33% of NDCs unavailable Medicaid use (2026): ~7,333 Rx

Why: Other; Demand increase for the drug; Discontinuation of the manufacture of the drug

Reporting: Accord Healthcare Inc., Armas Pharmaceuticals Inc, Bristol Myers Squibb Co., Dr. Reddy's Laboratories, Inc. and 5 more

Amino Acid Injection (Premasol 10% Sulfite Free in VIAFLEX Plastic Container, Travasol) View full page → Current ⚠ Supply risk: Low 2,129 days · 5.8 yr 16 NDCs 3 companies reporting Gastroenterology First posted Dec 8, 2020 Updated Oct 2, 2026

Amino acid injection is in shortage, with two specific formulations — Aminosyn-PF 7% and Aminosyn-PF 10% — currently having no available source from any reporting manufacturer. Other strengths and formulations still have supply listed.

Supply risk: Low · 2/5 risk factors 4/5 strengths / sizes still listed 3/3 reporting makers with supply 19% of NDCs unavailable Medicaid use (2026): ~59,472 Rx

Why: Shortage of an active ingredient; Shortage of an inactive ingredient component

Reporting: B. Braun Medical Inc., Baxter Healthcare, Otsuka ICU Medical LLC

Dexmedetomidine Hydrochloride Injection (Precedex) View full page → Current ⚠ Supply risk: Low ✓ 5 other companies list it 2,371 days · 6.5 yr 59 NDCs 17 companies reporting Anesthesia First posted Apr 10, 2020 Updated Oct 5, 2026

Dexmedetomidine hydrochloride injection is in a shortage that has lasted over a year, with the 200 mcg/2 mL strength currently having no available source from any reporting maker. Most strengths are still listed by other manufacturers not reporting a shortage, including Precedex (dexmedetomidine hydrochloride) from Hospira.

Supply risk: Low · 2/5 risk factors 19/20 strengths still listed 12/17 reporting makers with supply 5 other companies listing it 20% of NDCs unavailable Medicaid use (2025): ~26,561 Rx

Why: Other; Discontinuation of the manufacture of the drug; Demand increase for the drug

Reporting: Accord Healthcare Inc., Amneal Pharmaceuticals, Azurity Pharmaceuticals, Inc, Baxter Healthcare and 13 more

Furosemide Injection View full page → Current ⚠ Supply risk: Low ✓ 12 other companies list it 2,374 days · 6.5 yr 30 NDCs 8 companies reporting Cardiovascular First posted Apr 7, 2020 Updated Oct 3, 2026

Furosemide injection is currently in shortage, with some manufacturers facing manufacturing delays or backorder situations that have lasted over a year. Other manufacturers — including Hikma, Sagent, Camber, and Heritage/Avet — have not reported a shortage and still list this medicine as available.

Supply risk: Low · 1/5 risk factors 8/8 strengths still listed 6/8 reporting makers with supply 12 other companies listing it 44% of NDCs unavailable Medicaid use (2026): ~28,014 Rx

Why: Other; Requirements related to complying with good manufacturing practices; Discontinuation of the manufacture of the drug

Reporting: Accord Healthcare Inc., Avet Pharmaceuticals, Inc., Baxter Healthcare, Eugia US LLC and 4 more

Midazolam Hydrochloride Injection View full page → Current ⚠ Supply risk: Low ✓ 5 other companies list it 2,379 days · 6.5 yr 27 NDCs 6 companies reporting Anesthesia, Neurology First posted Apr 2, 2020 Updated Oct 1, 2026

Midazolam hydrochloride injection is currently in shortage, with some strengths having no available source right now. Other manufacturers not reporting a shortage still list several strengths of midazolam injection as available.

Supply risk: Low · 2/5 risk factors 6/10 strengths still listed 5/6 reporting makers with supply 5 other companies listing it 37% of NDCs unavailable Medicaid use (2026): ~246,667 Rx

Why: Demand increase for the drug; Other; Delay in shipping of the drug

Reporting: Avet Pharmaceuticals, Inc., Fresenius Kabi USA, LLC, Gland Pharma Limited, Hikma Pharmaceuticals USA, Inc. and 2 more

Echothiophate Iodide Ophthalmic Solution (Phospholine Iodide) View full page → Current ⚠ Supply risk: Medium 2,570 days · 7.0 yr 1 NDC Ophthalmology First posted Sep 24, 2019 Updated Sep 1, 2026

Phospholine Iodide (echothiophate iodide) eye drops are in shortage, and this has been ongoing for over a year. The 0.125% strength is still available but only through Walgreens Specialty Pharmacy.

Supply risk: Medium · 3/5 risk factors 1/1 strength still listed 1/1 reporting maker with supply 0% of NDCs unavailable Medicaid use (2025): ~56 Rx

Why: Other

Reporting: Fera Pharmaceuticals

Dexamethasone Sodium Phosphate Injection View full page → Current ⚠ Supply risk: Low ✓ 9 other companies list it 2,798 days · 7.7 yr 19 NDCs 5 companies reporting Dermatology, Endocrinology/Metabolism,... First posted Feb 8, 2019 Updated Oct 5, 2026

Dexamethasone sodium phosphate injection has been in short supply for over a year due to increased demand. Both the 4 mg/mL and 10 mg/mL strengths are still listed as available from multiple manufacturers not reporting a shortage, including Sagent Pharmaceuticals, Eugia US LLC, and others.

Supply risk: Low · 1/5 risk factors 2/2 strengths still listed 5/5 reporting makers with supply 9 other companies listing it 0% of NDCs unavailable Medicaid use (2026): ~1,101,858 Rx

Why: Demand increase for the drug

Reporting: Eugia US LLC, Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc., Mylan Institutional, a Viatris Company and 1 more

Lorazepam Injection (Ativan) View full page → Current ⚠ Supply risk: Medium ✓ 2 other companies list it 3,079 days · 8.4 yr 11 NDCs 4 companies reporting Neurology First posted May 3, 2018 Updated Sep 22, 2026

Most Ativan (lorazepam) injection products are short or on backorder, though Ativan brand still has one product in limited supply. The 4 mg/mL strength has no listed source from any manufacturer right now; the 2 mg/mL strength remains listed by makers that have not reported a shortage.

Supply risk: Medium · 3/5 risk factors 2/3 strengths still listed 3/4 reporting makers with supply 2 other companies listing it 64% of NDCs unavailable Medicaid use (2025): ~46,037 Rx

Why: Other; Demand increase for the drug

Reporting: Amphastar Pharmaceuticals, Inc., Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc., Hospira, Inc., a Pfizer Company

Ketorolac Tromethamine Injection View full page → Current ⚠ Supply risk: Medium ✓ 10 other companies list it 3,120 days · 8.5 yr 25 NDCs 7 companies reporting Analgesia/Addiction First posted Mar 23, 2018 Updated Oct 2, 2026

Ketorolac tromethamine injection is currently in shortage, driven by shipping delays and rising demand, with the 60 mg/2 mL (30 mg/mL) concentration having no available source right now. Other strengths remain listed by several manufacturers not reporting a shortage, including the 15 mg/mL and 30 mg/mL concentrations.

Supply risk: Medium · 3/5 risk factors 3/4 strengths still listed 5/7 reporting makers with supply 10 other companies listing it 52% of NDCs unavailable Medicaid use (2026): ~949,471 Rx

Why: Other; Demand increase for the drug; Delay in shipping of the drug

Reporting: Alembic Pharmaceuticals, Baxter Healthcare, Fresenius Kabi USA, LLC, Gland Pharma Limited and 3 more

Ropivacaine Hydrochloride Injection (Naropin) View full page → Current ⚠ Supply risk: Low ✓ 9 other companies list it 3,120 days · 8.5 yr 49 NDCs 5 companies reporting Anesthesia First posted Mar 23, 2018 Updated Oct 2, 2026

Some generic versions of Naropin (ropivacaine) injection are in short supply, though this shortage has lasted over a year. Naropin brand products are mostly still available, and multiple strengths of the generic can still be found through manufacturers not reporting a shortage.

Supply risk: Low · 1/5 risk factors 4/4 strengths still listed 5/5 reporting makers with supply 9 other companies listing it 24% of NDCs unavailable Medicaid use (2026): ~28,882 Rx

Why: Other; Demand increase for the drug; Delay in shipping of the drug

Reporting: Caplin Steriles, Ltd., Eugia US LLC, Fresenius Kabi USA, LLC, InfoRLife SA and 1 more

Bupivacaine Hydrochloride Injection (Marcaine, Sensorcaine) View full page → Current ⚠ Supply risk: Low ✓ 9 other companies list it 3,151 days · 8.6 yr 62 NDCs 8 companies reporting Anesthesia First posted Feb 20, 2018 Updated Oct 2, 2026

Most of the shortage affects generic bupivacaine hydrochloride injection, while Marcaine and Sensorcaine brand products remain mostly available. Generic versions are still listed by several manufacturers not reporting a shortage, though one strength — 0.75% 15 mg/2 mL in Dextrose 8.25% — currently has no listed source.

Supply risk: Low · 2/5 risk factors 16/17 strengths still listed 7/8 reporting makers with supply 9 other companies listing it 7% of NDCs unavailable Medicaid use (2025): ~127,005 Rx

Why: Discontinuation of the manufacture of the drug; Demand increase for the drug; Other

Reporting: Aspiro Pharma Limited, Eugia US LLC, Fresenius Kabi USA, LLC, Hospira, Inc., a Pfizer Company and 4 more

Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection (Sensorcaine, Marcaine With Epinephrine) View full page → Current ⚠ Supply risk: Medium 3,151 days · 8.6 yr 20 NDCs 2 companies reporting Anesthesia First posted Feb 20, 2018 Updated Sep 22, 2026

The generic versions of bupivacaine with epinephrine injection are almost entirely unavailable, while brand-name Sensorcaine and Marcaine With Epinephrine products are mostly still available. Several strengths have no listed source from any maker right now, and Hospira does not expect recovery until December 2028.

Supply risk: Medium · 3/5 risk factors 9/15 strengths still listed 2/2 reporting makers with supply 35% of NDCs unavailable Medicaid use (2025): ~16,264 Rx

Why: Other; Delay in shipping of the drug

Reporting: Fresenius Kabi USA, LLC, Hospira, Inc., a Pfizer Company

Heparin Sodium Injection View full page → Current ⚠ Supply risk: Low 3,249 days · 8.9 yr 8 NDCs 4 companies reporting Hematology First posted Nov 14, 2017 Updated Oct 2, 2026

Heparin sodium injection is in short supply, and this shortage has lasted over a year. Some strengths are still available from certain manufacturers, and Baxter Healthcare offers a 200 USP units/100 mL option not currently reporting a shortage.

Supply risk: Low · 1/5 risk factors 3/3 strengths / sizes still listed 4/4 reporting makers with supply 13% of NDCs unavailable Medicaid use (2025): ~7,724 Rx

Why: Other

Reporting: B. Braun Medical Inc., Baxter Healthcare, Fresenius Kabi USA, LLC, Hospira, Inc., a Pfizer Company

Dobutamine Hydrochloride Injection View full page → Current ⚠ Supply risk: Low ✓ 2 other companies list it 3,257 days · 8.9 yr 10 NDCs 3 companies reporting Cardiovascular, Pediatric, Renal First posted Nov 6, 2017 Updated Oct 2, 2026

Dobutamine hydrochloride injection is currently in shortage, with some manufacturers reporting manufacturing delays and limited supply. Most strengths still have at least one listed source, so supply is not completely unavailable — but the shortage has lasted over a year.

Supply risk: Low · 1/5 risk factors 8/8 strengths still listed 3/3 reporting makers with supply 2 other companies listing it 10% of NDCs unavailable Medicaid use (2026): ~3,554 Rx

Why: Other

Reporting: Baxter Healthcare, Hainan Poly Pharm. Co., Ltd., Hospira, Inc., a Pfizer Company

Dopamine Hydrochloride Injection View full page → Current ⚠ Supply risk: Low 3,257 days · 8.9 yr 11 NDCs 3 companies reporting Cardiovascular First posted Nov 6, 2017 Updated Oct 2, 2026

Dopamine hydrochloride injection is in a shortage that has lasted over a year, with some strengths — 800 mg/500 mL and 40 mg/1 mL — currently having no listed supply from any maker. Most other strengths still have at least one available source among the manufacturers reporting the shortage.

Supply risk: Low · 2/5 risk factors 6/8 strengths still listed 2/3 reporting makers with supply 27% of NDCs unavailable Medicaid use (2026): ~226 Rx

Why: Demand increase for the drug; Other

Reporting: Baxter Healthcare, Hikma Pharmaceuticals USA, Inc., Hospira, Inc., a Pfizer Company

Hydromorphone Hydrochloride Injection (Dilaudid) View full page → Current ⚠ Supply risk: Low 3,263 days · 8.9 yr 26 NDCs 4 companies reporting Analgesia/Addiction First posted Oct 31, 2017 Updated Oct 1, 2026

Hydromorphone injection is in shortage, with a few specific low-dose strengths currently having no available source. Most strengths are still listed by other makers, including Hospira and Hikma Pharmaceuticals.

Supply risk: Low · 2/5 risk factors 9/12 strengths still listed 4/4 reporting makers with supply 35% of NDCs unavailable Medicaid use (2026): ~181,547 Rx

Why: Other; Demand increase for the drug

Reporting: Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc., Hospira, Inc., a Pfizer Company, Teva Pharmaceuticals USA, Inc.

Morphine Sulfate Injection (Duramorph, Mitigo) View full page → Current ⚠ Supply risk: Low ✓ 1 other company lists it 3,263 days · 8.9 yr 24 NDCs 5 companies reporting Analgesia/Addiction First posted Oct 31, 2017 Updated Sep 22, 2026

Morphine sulfate injection is currently in shortage, with four specific strengths — including 5 mg/1 mL, 8 mg/1 mL, 50 mg/1 mL, and 10 mg/1 mL syringes — having no available source right now. Many other strengths remain listed by multiple manufacturers not reporting a shortage.

Supply risk: Low · 2/5 risk factors 12/16 strengths still listed 5/5 reporting makers with supply 1 other company listing it 46% of NDCs unavailable Medicaid use (2026): ~236,809 Rx

Why: Other; Demand increase for the drug; Discontinuation of the manufacture of the drug

Reporting: Amphastar Pharmaceuticals, Inc., Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc., Hospira, Inc., a Pfizer Company and 1 more

Sodium Bicarbonate Injection View full page → Current ⚠ Supply risk: Low ✓ 7 other companies list it 3,507 days · 9.6 yr 15 NDCs 5 companies reporting Endocrinology/Metabolism, Gastroentero... First posted Mar 1, 2017 Updated Oct 1, 2026

Sodium Bicarbonate Injection is in shortage, with the 75 mg/mL strength currently having no available source due to manufacturing delays and rising demand. Most other strengths are still listed as available from makers not reporting a shortage.

Supply risk: Low · 2/5 risk factors 4/5 strengths still listed 5/5 reporting makers with supply 7 other companies listing it 9% of NDCs unavailable Medicaid use (2025): ~29,957 Rx

Why: Other; Demand increase for the drug

Reporting: Amphastar Pharmaceuticals, Inc., Exela Pharma Sciences, LLC, Fresenius Kabi USA, LLC, Hospira, Inc., a Pfizer Company and 1 more

Sodium Acetate Injection View full page → Current ⚠ Supply risk: Low ✓ 1 other company lists it 3,899 days · 10.7 yr 15 NDCs 5 companies reporting Endocrinology/Metabolism, Gastroentero... First posted Feb 3, 2016 Updated Oct 1, 2026

Sodium Acetate Injection is in a current shortage, though all five reporting manufacturers still list at least some supply available across most strengths. Additional supply is also listed by Amneal Pharmaceuticals, so the medicine has not disappeared from the market entirely.

Supply risk: Low · 1/5 risk factors 6/6 strengths still listed 5/5 reporting makers with supply 1 other company listing it 0% of NDCs unavailable Medicaid use (2025): ~20,526 Rx

Why: Other

Reporting: Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc., Hospira, Inc., a Pfizer Company, Milla Pharmaceuticals and 1 more

Cefotaxime Sodium Powder for Solution View full page → Current ⚠ Supply risk: High 4,250 days · 11.6 yr 6 NDCs 2 companies reporting Anti-Infective, Pediatric First posted Feb 17, 2015 Updated Sep 18, 2026

Cefotaxime sodium injection is in shortage due to increased demand, and has been for over a year. The 1 g and 2 g vials still have a source, but the 500 mg and 10 g sizes have no available supply from any reporting manufacturer right now.

Supply risk: High · 5/5 risk factors 2/4 strengths still listed 1/2 reporting makers with supply 67% of NDCs unavailable

Why: Demand increase for the drug

Reporting: Hikma Pharmaceuticals USA, Inc., SteriMax, Inc.

Lidocaine Hydrochloride Injection (Xylocaine) View full page → Current ⚠ Supply risk: Low ✓ 11 other companies list it 5,341 days · 14.6 yr 67 NDCs 10 companies reporting Anesthesia, Pediatric First posted Feb 22, 2012 Updated Oct 5, 2026

Generic lidocaine hydrochloride injection is in shortage, while Xylocaine (lidocaine hydrochloride) brand products are mostly available. Some generic strengths remain listed by manufacturers not reporting the shortage, but a few specific strengths have no listed source from any reporting company right now.

Supply risk: Low · 2/5 risk factors 28/31 strengths still listed 8/10 reporting makers with supply 11 other companies listing it 29% of NDCs unavailable Medicaid use (2026): ~374,161 Rx

Why: Demand increase for the drug; Other

Reporting: Amphastar Pharmaceuticals, Inc., Anthea Pharma, B. Braun Medical Inc., Baxter Healthcare and 6 more

Epinephrine Bitartrate, Lidocaine Hydrochloride Injection (Xylocaine) View full page → Current ⚠ Supply risk: Low ✓ 2 other companies list it 5,341 days · 14.6 yr 22 NDCs 2 companies reporting Anesthesia, Pediatric First posted Feb 22, 2012 Updated Sep 22, 2026

Some strengths of lidocaine with epinephrine injection are currently unavailable due to manufacturing delays at Pfizer (Hospira), with recovery for affected strengths estimated between late 2026 and late 2028. Several other strengths remain listed by makers not reporting a shortage, including Fresenius Kabi USA and others.

Supply risk: Low · 2/5 risk factors 10/16 strengths still listed 2/2 reporting makers with supply 2 other companies listing it 41% of NDCs unavailable Medicaid use (2026): ~36,311 Rx

Why: Other; Demand increase for the drug

Reporting: Fresenius Kabi USA, LLC, Hospira, Inc., a Pfizer Company

Atropine Sulfate Injection View full page → Current ⚠ Supply risk: Low ✓ 3 other companies list it 5,393 days · 14.8 yr 19 NDCs 8 companies reporting Anesthesia, Neurology, Pediatric First posted Jan 1, 2012 Updated Oct 3, 2026

Atropine sulfate injection has been on the FDA shortage list for over a year, with some strengths — including 0.05 mg/mL and certain 0.1 mg/mL glass syringes — currently having no listed source. Other strengths remain available from manufacturers not reporting a shortage.

Supply risk: Low · 2/5 risk factors 5/8 strengths / sizes still listed 8/8 reporting makers with supply 3 other companies listing it 35% of NDCs unavailable Medicaid use (2025): ~9,690 Rx

Why: Requirements related to complying with good manufacturing practices; Discontinuation of the manufacture of the drug; Other

Reporting: Accord Healthcare Inc., American Regent, Inc., Amphastar Pharmaceuticals, Inc., Fresenius Kabi USA, LLC and 4 more

Fentanyl Citrate Injection View full page → Current ⚠ Supply risk: Low ✓ 2 other companies list it 5,393 days · 14.8 yr 19 NDCs 3 companies reporting Analgesia/Addiction, Pediatric First posted Jan 1, 2012 Updated Sep 22, 2026

Fentanyl citrate injection is in a current shortage, driven by rising demand and lasting over a year. Some supply is still available through reporting manufacturers, and additional supply is listed by makers that have not reported a shortage.

Supply risk: Low · 1/5 risk factors 8/8 strengths still listed 3/3 reporting makers with supply 2 other companies listing it 21% of NDCs unavailable Medicaid use (2026): ~358,474 Rx

Why: Other; Demand increase for the drug

Reporting: Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc., Hospira, Inc., a Pfizer Company

Peginterferon Alfa-2A Injection (Pegasys) View full page → Resolved lasted 580 days · 1.6 yr 2 NDCs Antiviral First posted Jan 24, 2025 Updated Aug 27, 2026

Peginterferon Alfa-2A Injection is not in an active FDA shortage right now (last status “Resolved”, Aug 27, 2026).

Reported by: pharmaand GmbH (pharma&)

Albuterol Sulfate Solution View full page → Resolved lasted 1,402 days · 3.8 yr 3 NDCs 3 companies reporting Pediatric, Pulmonary/Allergy First posted Oct 25, 2022 Updated Aug 27, 2026

Albuterol Sulfate Solution is not in an active FDA shortage right now (last status “Resolved”, Aug 27, 2026).

Reported by: Nephron Pharmaceuticals Corporation, Rising Pharma Holdings, Inc., Ritedose Pharmaceuticals, LLC

Triamcinolone Acetonide Injection (Triesence) View full page → Resolved lasted 1,768 days · 4.8 yr 1 NDC Ophthalmology First posted Sep 27, 2021 Updated Jul 31, 2026

Triamcinolone Acetonide Injection is not in an active FDA shortage right now (last status “Resolved”, Jul 31, 2026).

Reported by: Harrow Eye, LLC

Rifapentine Tablet (Priftin) View full page → Resolved lasted 2,325 days · 6.4 yr 1 NDC Anti-Infective First posted Mar 25, 2020 Updated Aug 6, 2026

Rifapentine Tablet is not in an active FDA shortage right now (last status “Resolved”, Aug 6, 2026).

Reported by: Sanofi-Aventis U.S. LLC

Bumetanide Injection View full page → Resolved lasted 3,213 days · 8.8 yr 12 NDCs 5 companies reporting Cardiovascular First posted Dec 13, 2017 Updated Sep 30, 2026

Bumetanide Injection is not in an active FDA shortage right now (last status “Resolved”, Sep 30, 2026).

Reported by: Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc., MSN Laboratories Private Limited, Mullan Pharmaceutical Inc. and 1 more

How we rate supply risk
LowMost strengths or pack sizes are still made by some company, from several companies — including companies not reporting a shortage.
MediumA strength/size gap or a single remaining supplier — workable, but worth watching.
HighSeveral strengths or pack sizes can’t be sourced, or no manufacturer reports available supply.

A transparent, rule-based rating. We check 5 things: (1) is every strength or pack size still made by some company, (2) can more than one company still supply it, (3) how many NDCs are unavailable, (4) how long it’s lasted (we count a shortage as long-running once it passes about 3 months, one calendar quarter — a company’s discontinuation notice is not an outage, so its age does not count), and (5) how many companies list it. Checks 1, 2 and 5 count both the companies reporting the shortage and the companies that list the same medicine with the FDA without a shortage report. The level is the number of those checks that are currently a risk factor, shown as a tier: 0-2 = Low, 3 = Medium, 4-5 = High. One exception: a complete outage — no affected strength or pack size has any listed source and no second supplier exists — always rates 5 of 5, even when the shortage is new. It’s a national signal, not your local pharmacy’s stock; alternatives may not be clinically interchangeable. The five checks for each drug are on its full page.

What FDA’s shortage terms meanstatuses & the reasons you’ll see

Status & availability

Currently in shortage
Demand (or projected demand) for the drug in the U.S. exceeds supply.
Resolved
FDA determined supply is no longer exceeded by demand. Kept here for history.
To be discontinued
The manufacturer has notified FDA it will permanently stop making this product (a section 506C discontinuation notice). Informational only.
Available
The manufacturer’s most current report that a product is in supply — not an FDA determination that the shortage is resolved.

Reason for shortage

Under section 506E of the FD&C Act, a shortage may be attributed to:

  • Requirements related to complying with good manufacturing practices
  • Regulatory delay
  • Shortage of an active ingredient
  • Shortage of an inactive ingredient component
  • Discontinuation of the manufacture of the drug
  • Delay in shipping of the drug
  • Demand increase for the drug
  • Other — the manufacturer’s reason doesn’t fit a category above

Therapeutic category describes where a drug is commonly used (e.g. Pediatrics); it does not reflect FDA-approved status. All product, availability and reason details are provided by the manufacturer (via FDA) and can change daily.

Drug shortage FAQs

What does it mean when a drug is “in shortage”?
A drug is in shortage when U.S. demand (or projected demand) is greater than the supply available. The FDA maintains the official Drug Shortages database, which is what this page is built from. A shortage is national and manufacturer-reported, so it does not always mean your local pharmacy is out.
Why do drug shortages happen?
The FDA records a reason for each shortage. Common ones include manufacturing or quality problems, a shortage of an active or inactive ingredient, manufacturing or shipping delays, a manufacturer discontinuing the product, a sharp increase in demand, or a regulatory delay. A single drug can have more than one reason across its products.
A medicine I take is on the list. What should I do?
Do not stop, skip, or change your doses on your own. Ask your pharmacy to check wholesalers and other manufacturers for remaining supply, ask whether they can order the same medicine from a different maker, and talk with your prescriber about options before your supply runs out. Each drug’s full shortage page lists the companies reporting it, their contact numbers, and the other companies that list the same medicine without a shortage report.
Does “in shortage” mean my pharmacy is out of it?
Not necessarily. This is national, manufacturer-reported data. Your pharmacy may still have stock or be able to order it, and supply can change daily. Always confirm with your pharmacy.
What does “to be discontinued” mean?
It means the manufacturer has notified the FDA that it plans to permanently stop making that product. This is often a permanent change rather than a temporary supply gap, so a conversation with your prescriber about a long-term plan is the right next step.
What is the Supply-Risk rating on each drug?
It is our own rule-based score from 0 to 5 risk factors, shown as a tier (0–2 Low, 3 Medium, 4–5 High). It checks whether each strength is still listed by some company, whether more than one company still lists the medicine, how many of the reported NDCs are unavailable, how long the shortage has lasted, and how many companies list the medicine at all. It counts both the companies reporting the shortage and the companies listing the same medicine without a report, and it treats a company’s discontinuation notice as that company stopping its product, not as an outage. It is a national signal to help gauge severity, not medical advice.
What does the Medicaid use figure represent?
It is the total Medicaid prescriptions over the most recent year of CMS State Drug Utilization Data, added up across the NDCs on that shortage report. We use it as a proxy for how widely a drug is used. It covers Medicaid patients only and may not represent the whole U.S. population.
How often is this page updated?
We refresh the shortage list from the FDA openFDA Drug Shortages database every day, and the supply-risk ratings and patient guidance update along with it.
Where does the data come from?
Shortage records come from the FDA Drug Shortages database (via openFDA). Alternative products and manufacturer counts come from the FDA NDC Directory, and utilization figures come from CMS Medicaid State Drug Utilization Data. This information is for reference only and is not medical advice.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates, grouped by FDA active ingredient then manufacturer. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data (SDUD) (per 100k uses 2023 U.S. Census population). Utilization shown is Medicaid only (CMS State Drug Utilization Data). It has reporting gaps and under-represents drugs used mainly outside Medicaid — treat it as a relative signal, not total U.S. use. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.