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Etomidate Injection shortage

Etomidate Injection is currently listed in shortage by the FDA. The FDA lists 18 affected products. The reported reason: Demand increase for the drug; Other. This page was last refreshed from FDA data on Sep 22, 2026.

Current ⚠ Supply risk: Low Anesthesia 18 products 6 manufacturers 1,449 days · 4.0 yr First posted Oct 5, 2022 Updated Sep 17, 2026
Here’s the bottom line

Etomidate injection is in shortage, with the larger vial sizes (20 mg/10 mL and 40 mg/20 mL) currently having no available source. The 2 mg/mL strength is still listed as available from several manufacturers, including Fresenius Kabi, which has not reported a shortage.

Don’t stop or change your therapy on your own — ask your pharmacist about other manufacturers (see options) and your prescriber about a long-term plan.

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
18
Affected NDCs
6
Reporting manufacturers
5/6
Reporting mfrs supplying
4/6
Affected strengths supplied
17%
NDCs unavailable
1,449
Days in shortage
795
Medicaid Rx (2025)
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Sep 22, 2026 · yesterday

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Etomidate Injection. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
18 NDCs
Available 15 Unavailable 3
Affected strengths still supplied
Among manufacturers reporting this shortage
4/6 strengths
Sourceable 4 No supply 2
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
5/6 makers
With supply 5 No supply 1
✓ Other manufacturers not reporting a shortage
Still-marketed Etomidate Injection from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
Fresenius Kabi USA, LLC
See all other options & details →
Shortage timeline
  1. Sep 17, 2026
    Currently in shortage
    18 of 18 products affected.
  2. Sep 9, 2026
    FDA refreshed this shortage record
    1 product updated.
  3. Sep 3, 2026
    FDA refreshed this shortage record
    5 products updated.
  4. Aug 24, 2026
    FDA refreshed this shortage record
    1 product updated.
  5. Aug 13, 2026
    FDA refreshed this shortage record
    1 product updated.
  6. Jul 22, 2026
    FDA refreshed this shortage record
    2 products updated.
  7. Jun 16, 2026
    FDA refreshed this shortage record
    4 products updated.
  8. Oct 5, 2022
    First reported to the FDA
    18 products first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Caplin Steriles, Ltd. 📞 908-803-2586 4 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Etomidate, Injection, 2 mg/mL (NDC 72485-509-10) NDC 72485-0509-10 Available Check wholesalers for inventory; Marketed by Armas Pharmaceuticals, Inc. 908-803-2586
Current Etomidate, Injection, 2mg/mL (NDC 65219-447-20) NDC 65219-0447-20 Available Check wholesalers for inventory; Marketed by Fresenius Kabi
Current Etomidate, Injection, 2mg/1 mL (NDC 65219-445-10) NDC 65219-0445-10 Available Check wholesalers for inventory; Marketed by Fresenius Kabi
Current Etomidate, Injection, 2 mg/mL (NDC 72485-508-10) NDC 72485-0508-10 Available Check wholesalers for inventory; Marketed by Armas Pharmaceuticals, Inc. 908-803-2586
Manufacturer: Eugia US LLC 📞 888-238-7880 2 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Etomidate, Injection, 40 mg/20 mL (NDC 55150-222-20) NDC 55150-0222-20 Unavailable On backorder. Recovery: TBD. Check wholesalers for inventory Demand increase for the drug
Current Etomidate, Injection, 20 mg/10 mL (NDC 55150-221-10) NDC 55150-0221-10 Unavailable On backorder. Recovery: TBD. Check wholesalers for inventory Demand increase for the drug
Manufacturer: Gland Pharma Limited 📞 833-291-9645 2 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Etomidate, Injection, 2 mg/1 mL (NDC 72266-147-10) NDC 72266-0147-10 Available Distributed by Fosun Pharma USA, Inc.. To order, contact: 833-291-9645.
Current Etomidate, Injection, 2 mg/1 mL (NDC 72266-146-10) NDC 72266-0146-10 Available Distributed by Fosun Pharma USA, Inc.. To order, contact: 833-291-9645.
Manufacturer: Hikma Pharmaceuticals USA, Inc. 📞 800-631-2174 6 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Etomidate, Injection, 2 mg/1 mL (NDC 72572-161-10) NDC 72572-0161-10 Available Distributed by Civica
Current Etomidate, Injection, 2 mg/1 mL (NDC 0143-9507-10) NDC 00143-9507-10 Available Additional product will be made available as it is released.
Current Etomidate, Injection, 2 mg/1 mL (NDC 0143-9311-10) NDC 00143-9311-10 Available Novaplus label
Current Etomidate, Injection, 2 mg/1 mL (NDC 0143-9310-10) NDC 00143-9310-10 Available Novaplus label
Current Etomidate, Injection, 2 mg/1 mL (NDC 72572-160-10) NDC 72572-0160-10 Available Distributed by Civica
Current Etomidate, Injection, 2 mg/1 mL (NDC 0143-9506-10) NDC 00143-9506-10 Available Additional product will be made available as it is released.
Manufacturer: Hospira, Inc., a Pfizer Company 📞 844-646-4398 2 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Amidate, Injection, 2 mg/1 mL (NDC 0409-6695-01) NDC 00409-6695-01 Available
Current Amidate, Injection, 2 mg/mL (NDC 0409-6695-02) NDC 00409-6695-02 Unavailable Next Delivery: November 2026; Estimated Recovery: December 2026. Shortage per Manufacturer: Manufacturing Delay Other
Manufacturer: Mylan Institutional, a Viatris Company 📞 800-796-9526 2 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Etomidate, Injection, 2 mg/1 mL (NDC 67457-903-20) NDC 67457-0903-20 Available
Current Etomidate, Injection, 2 mg/1 mL (NDC 67457-902-10) NDC 67457-0902-10 Available

These rows are manufacturer reports to the FDA for Etomidate Injection — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Etomidate Injection? options further down this page.

Why is Etomidate Injection in shortage?

Etomidate injection (2 mg/mL) is on the FDA shortage list mainly because more people need it than the current supply can keep up with, and there are also some manufacturing hold-ups at certain facilities. Specifically, two of Eugia US LLC's products — the 20 mg/10 mL and 40 mg/20 mL vials — are both on backorder with no confirmed recovery date yet. On top of that, one of Hospira's (a Pfizer company) Amidate 2 mg/mL products is currently unavailable due to a manufacturing delay, with the next delivery not expected until November 2026 and a recovery estimated around December 2026.

It's worth knowing that Hospira's other Amidate 2 mg/1 mL product is still available, and several other manufacturers — including Hikma, Mylan, Caplin Steriles, and Gland Pharma — are reporting their 2 mg/mL vials as currently available, though some note that inventory may be limited and you'd need to check with wholesalers. This shortage report only reflects what these specific manufacturers have shared with the FDA.

FDA reason code(s): Demand increase for the drug; Other

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Etomidate Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Etomidate Injection?

Etomidate injection is currently on the FDA drug-shortage list. Because this medicine is given in clinical settings such as hospitals and procedure areas, most of what follows is handled by your care team, but I want you to understand where supply stands.

The affected sizes are the 20 mg/10 mL and 40 mg/20 mL vials, which currently have no available source and are on backorder with a recovery time still to be determined. The smaller 2 mg/mL (also listed as 2 mg/1 mL) concentration still has supply reported from several makers, so the strength many patients receive is generally obtainable.

This shortage has lasted more than a year, and the reported reasons are increased demand and "other" factors. Importantly, 5 of 6 manufacturers still report available supply, so this is a limited-source issue rather than a full outage.

Here is what you can do:

  • Do not skip or change any dose on your own — this medicine is dosed and given by your care team.
  • If your setting uses the 2 mg/mL size, your pharmacy can order it and check wholesalers and other manufacturers.
  • If the 10 mL or 20 mL vial you need cannot be found, your pharmacist or prescriber can discuss options, such as using an available concentration.
  • Manufacturer contact numbers are listed on this page for reference; pharmacies usually make these calls.

This is national, manufacturer-reported data and may not match local stock.

See “Where else can I get Etomidate Injection?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Etomidate guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Etomidate guide →

Where else can I get Etomidate Injection?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Etomidate Injection is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Same medicine, other manufacturers (not reported short)

Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:

ProductStrengthForm / routeManufacturerNDC
Etomidate ETOMIDATE 2 mg/mL Injection, Solution · Intravenous Fresenius Kabi USA, LLC 65219-0445-22
Therapeutic equivalents & pricing 25 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Etomidate 2 mg/mLNDC 00143-9311-10 Hikma 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 00143-9507-10 Hikma 10 vials AP FDA listed
Amidate 2 mg/mLNDC 00409-6695-01 Hospira, 10 vials AP FDA listed
Etomidate 40 mg/20mLNDC 51662-1542-01 HF 20 ml AP FDA listed
Etomidate 40 mg/20mLNDC 55150-0222-20 Eugia 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 65145-0128-10 Caplin 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 65219-0447-20 Fresenius 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 67457-0903-20 Mylan 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 68083-0235-10 Gland 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 72266-0147-10 Fosun 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 72485-0509-10 Armas 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 72572-0161-10 Civica, 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 00143-9310-10 Hikma 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 00143-9506-10 Hikma 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 65219-0445-10 Fresenius 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 72572-0160-10 Civica, 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 51662-1485-01 HF 10 ml AP FDA listed
Etomidate 2 mg/mLNDC 72485-0508-10 Armas 10 vials AP FDA listed
Amidate 2 mg/mLNDC 00404-9811-10 Henry 1 vial AP FDA listed
Etomidate 2 mg/mLNDC 67457-0902-10 Mylan 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 65145-0127-10 Caplin 10 vials AP FDA listed
ETOMIDATE injection, solution 20 mg/10mLNDC 51662-1634-01 HF 10 ml AP FDA listed
Etomidate 20 mg/10mLNDC 55150-0221-10 Eugia 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 68083-0234-10 Gland 10 vials AP FDA listed
Etomidate 2 mg/mLNDC 72266-0146-10 Fosun 10 vials AP FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Etomidate Injection — that fall in the same broad treatment class (general anesthetics,injectable) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 030871
GCN 12831
HICL code 001554
Ingredient (HICL) Etomidate
HIC1 code H
Therapeutic class — broad (HIC1) Nervous System (Except Autonomic)
HIC2 code H2
Therapeutic class — intermediate (HIC2) Psychoactive Drugs
HIC3 code H2C
Therapeutic class — specific (HIC3) General Anesthetics,Injectable
AHFS code 28:04.08.00
AHFS class Non-Barbiturates
FDB label name ETOMIDATE 40 MG/20 ML VIAL
FDB brand name Etomidate
Legend status F — Federal legend — prescription drug or device
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other anesthesia shortages

Etomidate Injection shortage FAQs

Is Etomidate Injection in shortage?
Yes — the FDA currently lists Etomidate Injection in shortage (status: “Current”, first reported Oct 5, 2022). 18 of 18 products are affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Why is Etomidate Injection in shortage?
The manufacturer-reported reason on file with the FDA: Demand increase for the drug; Other.
Which products are affected?
Etomidate, Injection, 2 mg/mL (NDC 72485-509-10) (NDC 72485-0509-10); Etomidate, Injection, 2mg/mL (NDC 65219-447-20) (NDC 65219-0447-20); Etomidate, Injection, 2mg/1 mL (NDC 65219-445-10) (NDC 65219-0445-10). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Etomidate Injection be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Etomidate somewhere?
Other manufacturers (Fresenius Kabi USA, LLC) still market it and have not reported a shortage. See “Where else can I get Etomidate Injection?” above — stock still varies by pharmacy.
What should I do if I take Etomidate Injection?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Etomidate Injection shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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