Drug Launch Tracker

When Will Your Drug Go Generic?

Look up a brand-name drug to see the month its first, lower-cost generic is expected, the reason, how sure we are, and how much price competition is lined up.

Dr. Brian Staiger, PharmD, BCPS

This page is aggregated from FDA records, court filings and company announcements. Coded and designed by

Updated October 9, 2026 How we build our data

Coming Up Next

Tap a card for that drug’s launch page; tap or hover a dotted label for what it means.

  • Expected generic launchOctober 2026 This month
    BrandAdasuve
    GenericLoxapine
    Why it’s going genericPatent expires
    FilersNone yet
    Brand salesNot reported
  • Expected generic launchOctober 2026 This month
    BrandSynribo
    GenericOmacetaxine Mepesuccinate
    Why it’s going genericPatent expires
    Filers1 company
    Brand salesNot reported
  • Expected generic launchNovember 2026 Next month
    BrandHorizant
    GenericGabapentin Enacarbil
    Why it’s going genericPatent expires
    Filers3 companies
    Brand sales$82M a year
  • Expected generic launchDecember 2026 About 2 months away
    BrandTrintellix
    GenericVortioxetine Hydrobromide
    Why it’s going genericNot yet clear
    Filers16 companies
    Brand sales$1.4B a year
  • Expected generic launchDecember 2026 About 2 months away
    BrandSignifor
    GenericPasireotide Diaspartate
    Why it’s going genericPatent expires
    FilersNone yet
    Brand salesNot reported
  • Expected generic launchJanuary 2027 About 3 months away
    BrandVivitrol
    GenericNaltrexone
    Why it’s going genericSettlement between companies
    Filers1 company
    Brand sales$936M a year
  • Expected generic launchJanuary 2027 About 3 months away
    BrandBelbuca
    GenericBuprenorphine Hydrochloride
    Why it’s going genericSettlement between companies
    Filers7 companies
    Brand sales$370M a year
  • Expected generic launchJanuary 2027 About 3 months away
    BrandVibativ
    GenericTelavancin Hydrochloride
    Why it’s going genericPatent expires
    FilersNone yet
    Brand sales$4M a year

Big Names With a Date

The brands with the highest yearly sales that have a month or a window on the calendar.

  • Expected generic launchJanuary 2040 About 13.5 years away
    BrandMounjaro
    GenericTirzepatide
    Why it’s going genericPatent expires
    Filers10 companies
    Brand sales$41.5B a year
  • Expected generic launch2032 to 2033 A wide window
    BrandJardiance
    GenericEmpagliflozin
    Why it’s going genericSettlement between companies
    Filers21 companies
    Brand sales$28.1B a year
  • Expected generic launchJanuary 2040 About 13.5 years away
    BrandZepbound
    GenericTirzepatide
    Why it’s going genericPatent expires
    Filers11 companies
    Brand sales$26.8B a year
  • Expected generic launchApril 2028 About a year and a half away
    BrandEliquis 5 mg tablet
    GenericApixaban
    Why it’s going genericSettlement between companies
    Filers30 companies
    Brand sales$26.6B a year
  • Expected generic launch2035 to 2036 A wide window
    BrandWegovy injection
    GenericSemaglutide
    Why it’s going genericSettlement expected
    Filers2 companies
    Brand sales$19.9B a year
  • Expected generic launchApril 2036 About 9.5 years away
    BrandBiktarvy 50 mg/200 mg/25 mg
    GenericBictegravir Sodium, Emtricitabine, and Tenofovir Alafenamide Fumarate
    Why it’s going genericSettlement between companies
    Filers3 companies
    Brand sales$19.4B a year
  • Expected generic launch2031 to 2032 A wide window
    BrandOzempic 8 mg/3 mL
    GenericSemaglutide
    Why it’s going genericSettlement between companies
    Filers4 companies
    Brand sales$14.4B a year
  • Expected generic launch2031 to 2033 A wide window
    BrandOzempic 4 mg/3 mL
    GenericSemaglutide
    Why it’s going genericSettlement between companies
    Filers9 companies
    Brand sales$12.9B a year

Generic Launches by the Numbers

The year ahead at a glance: first generics expected each month, and the size of what is coming.

First generics expected, month by monthOct 2026 to Sep 2027 · drugs with an exact month
Oct ’26 Nov Dec 5 Jan ’27 Feb Mar Apr May Jun Jul Aug Sep
Show as a table
MonthFirst generics expected
October 20262
November 20261
December 20262
January 20275
February 20272
March 20270
April 20272
May 20274
June 20272
July 20273
August 20272
September 20273
84Brand-name drugs that could get a first generic in the next 12 months
911Brand-name drugs on the schedule
14Blockbusters ($1B+ a year) due to face generics by the end of 2028

Upcoming Generic Drug Launches by Month

Every expected first generic for the next 18 months. Every drug opens its own launch page with the patents, approvals and prices behind its month.

Show
Order

68 drugs could get a first generic in the next 6 monthsOct 2026 to Mar 2027

Tap any drug for its launch page. Tap or hover a column name for what it means.

What each reason means
Patent expires
A patent that protects the brand runs out. After that, approved generics can be sold.
Settlement between companies
The brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
Settlement expected
The patent fight is likely to end in an agreement that sets the launch. The terms are not public yet.
FDA exclusivity ends
FDA gives new drugs a protected period, for example for a rare-disease use. It ends then.
Court hold ends
When a generic maker challenges a patent, FDA must wait up to 30 months before approving it. That wait ends then.
Awaiting FDA approval
The patents are not the problem. A generic still needs FDA sign-off, and that is when it is expected.
Launch expected
A generic maker is expected to launch around then.
Not yet clear
The event that will open the door is not settled yet. Each row shows the public record behind it: how many makers have filed with FDA and any patent challenge under way.

October 2026

2 expected
Expected generic launchOct2026 This month

Adasuve

Generic name
Loxapine
How it’s taken
Inhaled
Good to know
Hard to copy
Coming soon
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Not rated Too early to rate. The month is where the records point today.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported
Expected generic launchOct2026 This month

Synribo

Generic name
Omacetaxine Mepesuccinate
How it’s taken
Injection under the skin
Coming soon
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
Low 1 company has filed
Brand sales
Sales not reported

November 2026

1 expected
Expected generic launchNov2026 Next month

Horizant

Generic name
Gabapentin Enacarbil
How it’s taken
By mouth
Coming soon
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 3 companies have filed, 1 first in line
Brand sales
$82M a yearSmaller seller

December 2026

2 expected
Expected generic launchDec2026 About 2 months away

Trintellix

Generic name
Vortioxetine Hydrobromide
How it’s taken
By mouth
Coming soon
Reason
Not yet clear16 generic makers have filed applications with FDA. What opens the door, a ruling, a deal or an expiry, is not settled yet.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 16 companies have filed, 15 first in line
Brand sales
$1.4B a yearBlockbuster
Expected generic launchDec2026 About 2 months away

Signifor

Generic name
Pasireotide Diaspartate
How it’s taken
Injection under the skin
Good to know
Hard to copy
Coming soon
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Probable More likely than not, but it can still move.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported

Sometime in 2026, no month yet

37 expected
Expected generic launchJul to Dec2026 A 6-month window

Tradjenta

Generic name
Linagliptin
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 18 companies have filed, 11 first in line
Brand sales
$1.4B a yearBlockbuster
Expected generic launchOct to Dec2026 A 3-month window

Adempas

Generic name
Riociguat
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 6 companies have filed, 3 first in line
Brand sales
$1.1B a yearBlockbuster
Expected generic launchDuring2026 Sometime that year

Tyvaso

Generic name
Treprostinil
How it’s taken
Inhaled
Good to know
Hard to copy
Reason
Awaiting FDA approvalThe patents are not the problem. A generic still needs FDA sign-off, and that is when it is expected.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$711M a yearBig seller
Expected generic launch2026to 2027 A wide window

Lutathera

Generic name
Lutetium Lu 177 Dotatate
How it’s taken
Into a vein (IV)
Good to know
Hard to copy
Reason
Launch expectedA generic maker is expected to launch around then.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$451M a yearBig seller
Expected generic launch2026to 2027 A wide window

Envarsus XR

Generic name
Tacrolimus
How it’s taken
By mouth
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Very strong 6 companies have filed, 1 first in line
Brand sales
$410M a yearBig seller
Expected generic launchDuring2026 Sometime that year

Jevtana Kit

Generic name
Cabazitaxel
How it’s taken
Into a vein (IV)
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Very strong 12 companies have filed, 8 first in line
Brand sales
$328M a yearBig seller
Expected generic launchJul to Dec2026 A 6-month window

Cerdelga

Generic name
Eliglustat Tartrate
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Very strong 6 companies have filed, 6 first in line
Brand sales
$226M a yearBig seller
Expected generic launchDuring2026 Sometime that year

Simbrinza

Generic name
Brimonidine Tartrate and Brinzolamide
How it’s taken
In the eye
Good to know
Hard to copy
Reason
Not yet clearOne generic maker has filed an application with FDA. What opens the door, a ruling, a deal or an expiry, is not settled yet.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$96M a yearSmaller seller
Expected generic launchJul to Dec2026 A 6-month window

Jentadueto

Generic name
Linagliptin and Metformin Hydrochloride
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Very strong 9 companies have filed, 7 first in line
Brand sales
$95M a yearSmaller seller
Expected generic launch2026to 2027 A wide window

Norepinephrine Bitartrate in Dextrose Injection Baxter

Generic name
Dextrose and Norepinephrine Bitartrate
How it’s taken
Into a vein (IV)
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 2 first in line
Brand sales
$72M a yearSmaller seller
Expected generic launch2026to 2027 A wide window

Firmagon

Generic name
Degarelix Acetate
How it’s taken
Injection under the skin
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Strong 4 companies have filed, 1 first in line
Brand sales
$60M a yearSmaller seller
Expected generic launchJul to Dec2026 A 6-month window

Jentadueto XR

Generic name
Linagliptin and Metformin Hydrochloride
How it’s taken
By mouth
Reason
Awaiting FDA approvalThe patents are not the problem. A generic still needs FDA sign-off, and that is when it is expected.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
$40M a yearSmaller seller
Expected generic launch2026to 2027 A wide window

Cresemba IV

Generic name
Isavuconazonium Sulfate
How it’s taken
Into a vein (IV)
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 2 first in line
Brand sales
$34M a yearSmaller seller
Expected generic launchDuring2026 Sometime that year

Yonsa

Generic name
Abiraterone Acetate
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$31M a yearSmaller seller
Expected generic launch2026to 2027 A wide window

Osphena

Generic name
Ospemifene
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$22M a yearSmaller seller
Expected generic launch2026to 2027 A wide window

Tirosint-Sol

Generic name
Levothyroxine Sodium
How it’s taken
By mouth
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$22M a yearSmaller seller
Expected generic launchDuring2026 Sometime that year

Natazia

Generic name
Dienogest and Estradiol Valerate
How it’s taken
By mouth
Reason
Not yet clear3 generic makers have filed applications with FDA. What opens the door, a ruling, a deal or an expiry, is not settled yet.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 3 companies have filed, 1 first in line
Brand sales
$21M a yearSmaller seller
Expected generic launch2026to 2027 A wide window

Bonjesta

Generic name
Doxylamine Succinate and Pyridoxine Hydrochloride
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
$20M a yearSmaller seller
Expected generic launchDuring2026 Sometime that year

Ella

Generic name
Ulipristal Acetate
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$17M a yearSmaller seller
Expected generic launchDuring2026 Sometime that year

Qbrelis

Generic name
Lisinopril
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
$14M a yearSmaller seller
Expected generic launch2026to 2027 A wide window

Lastacaft

Generic name
Alcaftadine
How it’s taken
In the eye
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Strong 5 companies have filed, 1 first in line
Brand sales
under $10M a yearSmall seller
Expected generic launchDuring2026 Sometime that year

Sernivo

Generic name
Betamethasone Dipropionate
How it’s taken
On the skin
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
$2M a yearSmaller seller
Expected generic launchDuring2026 Sometime that year

Bryhali

Generic name
Halobetasol Propionate
How it’s taken
On the skin
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
$1M a yearSmaller seller
Expected generic launchJul to Dec2026 A 6-month window

ZTlido 1.8%

Generic name
Lidocaine
How it’s taken
On the skin
Good to know
Hard to copy
Reason
Launch expectedA generic maker is expected to launch around then.
How sure
Very likely Few things could still move it, but a court ruling or a new deal can.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
Sales not reported
Expected generic launchOct to Dec2026 A 3-month window

Evomela

Generic name
Melphalan Hydrochloride
How it’s taken
Into a vein (IV)
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Very likely Few things could still move it, but a court ruling or a new deal can.
Price competition
Strong 4 companies have filed, 1 first in line
Brand sales
Sales not reported
Expected generic launchJul to Dec2026 A 6-month window

Ventavis

Generic name
Iloprost
How it’s taken
Inhaled
Good to know
Hard to copy
Reason
Launch expectedA generic maker is expected to launch around then.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed
Brand sales
Sales not reported
Expected generic launchJul to Dec2026 A 6-month window

Aplenzin 174 mg

Generic name
Bupropion Hydrobromide
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Strong 4 companies have filed, 1 first in line
Brand sales
Sales not reported
Expected generic launchJul to Dec2026 A 6-month window

Aplenzin 348 mg

Generic name
Bupropion Hydrobromide
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Strong 4 companies have filed, 1 first in line
Brand sales
Sales not reported
Expected generic launchJul to Dec2026 A 6-month window

Aplenzin 522 mg

Generic name
Bupropion Hydrobromide
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
Sales not reported
Expected generic launchDuring2026 Sometime that year

Byvalson

Generic name
Nebivolol and Valsartan
How it’s taken
By mouth
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
Sales not reported
Expected generic launchDuring2026 Sometime that year

Promacta 100 mg

Generic name
Eltrombopag Olamine
How it’s taken
By mouth
Reason
Not yet clear2 generic makers have filed applications with FDA. What opens the door, a ruling, a deal or an expiry, is not settled yet.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed
Brand sales
Sales not reported
Expected generic launchDuring2026 Sometime that year

Izba

Generic name
Travoprost
How it’s taken
In the eye
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
Sales not reported
Expected generic launchDuring2026 Sometime that year

Velphoro

Generic name
Ferric Oxyhydroxide
How it’s taken
By mouth
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Strong 4 companies have filed
Brand sales
Sales not reported
Expected generic launch2026to 2027 A wide window

Cubicin RF

Generic name
Daptomycin
How it’s taken
Into a vein (IV)
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Strong 4 companies have filed, 1 first in line
Brand sales
Sales not reported
Expected generic launch2026to 2027 A wide window

Beleodaq

Generic name
Belinostat
How it’s taken
Into a vein (IV)
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
Sales not reported
Expected generic launch2026to 2027 A wide window

Rydapt capsule

Generic name
Midostaurin
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Strong 5 companies have filed, 4 first in line
Brand sales
Sales not reported
Expected generic launch2026to 2027 A wide window

Arymo ER

Generic name
Morphine Sulfate
How it’s taken
By mouth
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
Sales not reported

January 2027

5 expected
Expected generic launchJan2027 About 3 months away

Vivitrol

Generic name
Naltrexone
How it’s taken
Injection into a muscle
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Very likely Few things could still move it, but a court ruling or a new deal can.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$936M a yearBig seller
Expected generic launchJan2027 About 3 months away

Belbuca

Generic name
Buprenorphine Hydrochloride
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 7 companies have filed, 3 first in line
Brand sales
$370M a yearBig seller
Expected generic launchJan2027 About 3 months away

Vibativ

Generic name
Telavancin Hydrochloride
How it’s taken
Into a vein (IV)
Coming soon
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
None filed yet No filers on record
Brand sales
$4M a yearSmaller seller
Expected generic launchJan2027 About 4 months away

Nevanac

Generic name
Nepafenac
How it’s taken
In the eye
Good to know
Hard to copy
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
None filed yet No filers on record
Brand sales
$4M a yearSmaller seller
Expected generic launchJan2027 About 4 months away

Kynamro

Generic name
Mipomersen Sodium
How it’s taken
Injection under the skin
Good to know
Hard to copy
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported

February 2027

2 expected
Expected generic launchFeb2027 About 4 months away

Altabax

Generic name
Retapamulin
How it’s taken
On the skin
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported
Expected generic launchFeb2027 About 5 months away

Vitekta

Generic name
Elvitegravir
How it’s taken
By mouth
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Probable More likely than not, but it can still move.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported

March 2027

1 expected
Expected generic launchMar2027 About 5 months away

Xarelto 10, 15, 20 mg tablets

Generic name
Rivaroxaban
How it’s taken
By mouth
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 32 companies have filed, 10 first in line
Brand sales
$9.3B a yearBlockbuster

April 2027

2 expected
Expected generic launchApr2027 About 7 months away

Amyvid

Generic name
Florbetapir F 18
How it’s taken
Into a vein (IV)
Good to know
Hard to copy
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Probable More likely than not, but it can still move.
Price competition
None filed yet No filers on record
Brand sales
$206M a yearBig seller
Expected generic launchApr2027 About 6 months away

Zilxi

Generic name
Minocycline
How it’s taken
On the skin
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Not rated Too early to rate. The month is where the records point today.
Price competition
None filed yet No filers on record
Brand sales
under $10M a yearSmall seller

May 2027

4 expected
Expected generic launchMay2027 About 7 months away

Aveed

Generic name
Testosterone Undecanoate
How it’s taken
Injection into a muscle
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$30M a yearSmaller seller
Expected generic launchMay2027 About 7 months away

Uptravi IV

Generic name
Selexipag
How it’s taken
Into a vein (IV)
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Strong 4 companies have filed, 1 first in line
Brand sales
Sales not reported
Expected generic launchMay2027 About 7 months away

Rapivab

Generic name
Peramivir
How it’s taken
Into a vein (IV)
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Probable More likely than not, but it can still move.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported
Expected generic launchMay2027 About 7 months away

Moxatag

Generic name
Amoxicillin
How it’s taken
By mouth
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported

June 2027

2 expected
Expected generic launchJun2027 About 8 months away

Orenitram

Generic name
Treprostinil Diolamine
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
$585M a yearBig seller
Expected generic launchJun2027 About 9 months away

Lumify

Generic name
Brimonidine Tartrate
How it’s taken
In the eye
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Very likely Few things could still move it, but a court ruling or a new deal can.
Price competition
Strong 5 companies have filed, 1 first in line
Brand sales
$43M a yearSmaller seller

July 2027

3 expected
Expected generic launchJul2027 About 10 months away

Doptelet

Generic name
Avatrombopag Maleate
How it’s taken
By mouth
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Probable More likely than not, but it can still move.
Price competition
None filed yet No filers on record
Brand sales
$525M a yearBig seller
Expected generic launchJul2027 About 9 months away

Relistor 12 mg/0.6 mL vial

Generic name
Methylnaltrexone Bromide
How it’s taken
Injection under the skin
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Strong 5 companies have filed, 2 first in line
Brand sales
$30M a yearSmaller seller
Expected generic launchJul2027 About 10 months away

Olysio

Generic name
Simeprevir Sodium
How it’s taken
By mouth
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Probable More likely than not, but it can still move.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported

August 2027

2 expected
Expected generic launchAug2027 About 10 months away

Lampit

Generic name
Nifurtimox
How it’s taken
By mouth
Good to know
Hard to copy
Reason
FDA exclusivity endsFDA gives new drugs a protected period, for example for a rare-disease use. It ends then.
How sure
Probable More likely than not, but it can still move.
Price competition
None filed yet No filers on record
Brand sales
under $10M a yearSmall seller
Expected generic launchAug2027 About 10 months away

Vistogard

Generic name
Uridine Triacetate
How it’s taken
By mouth
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported

September 2027

3 expected
Expected generic launchSep2027 About 11 months away

Zonisade

Generic name
Zonisamide
How it’s taken
By mouth
Reason
Court hold endsWhen a generic maker challenges a patent, FDA must wait up to 30 months before approving it. That wait ends then.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 3 companies have filed, 1 first in line
Brand sales
$63M a yearSmaller seller
Expected generic launchSep2027 About 12 months away

Solosec

Generic name
Secnidazole
How it’s taken
By mouth
Reason
FDA exclusivity endsFDA gives new drugs a protected period, for example for a rare-disease use. It ends then.
How sure
Probable More likely than not, but it can still move.
Price competition
None filed yet No filers on record
Brand sales
$2M a yearSmaller seller
Expected generic launchSep2027 About 11 months away

Edurant Ped

Generic name
Rilpivirine Hydrochloride
How it’s taken
By mouth
Reason
FDA exclusivity endsFDA gives new drugs a protected period, for example for a rare-disease use. It ends then.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
Sales not reported

October 2027

3 expected
Expected generic launchOct2027 About 12 months away

Xyzal Allergy 24Hr oral solution

Generic name
Levocetirizine Dihydrochloride
How it’s taken
By mouth
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Very likely Few things could still move it, but a court ruling or a new deal can.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
under $10M a yearSmall seller
Expected generic launchOct2027 About 13 months away

Bronchitol

Generic name
Mannitol
How it’s taken
Inhaled
Good to know
Hard to copy
Reason
FDA exclusivity endsFDA gives new drugs a protected period, for example for a rare-disease use. It ends then.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
None filed yet No filers on record
Brand sales
under $10M a yearSmall seller
Expected generic launchOct2027 About 13 months away

Elepsia XR

Generic name
Levetiracetam
How it’s taken
By mouth
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Not rated Too early to rate. The month is where the records point today.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported

November 2027

4 expected
Expected generic launchNov2027 About 13 months away

Fanapt

Generic name
Iloperidone
How it’s taken
By mouth
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 6 companies have filed, 1 first in line
Brand sales
$199M a yearBig seller
Expected generic launchNov2027 About 13 months away

Talicia

Generic name
Amoxicillin, Omeprazole Magnesium, and Rifabutin
How it’s taken
By mouth
Reason
FDA exclusivity endsFDA gives new drugs a protected period, for example for a rare-disease use. It ends then.
How sure
Probable More likely than not, but it can still move.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported
Expected generic launchNov2027 About 13 months away

Victrelis

Generic name
Boceprevir
How it’s taken
By mouth
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Not rated Too early to rate. The month is where the records point today.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported
Expected generic launchNov2027 About 13 months away

Zokinvy

Generic name
Lonafarnib
How it’s taken
By mouth
Reason
FDA exclusivity endsFDA gives new drugs a protected period, for example for a rare-disease use. It ends then.
How sure
Probable More likely than not, but it can still move.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported

December 2027

4 expected
Expected generic launchDec2027 About 14 months away

Xadago

Generic name
Safinamide
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 6 companies have filed, 6 first in line
Brand sales
Sales not reported
Expected generic launchDec2027 About 14 months away

Hetlioz LQ

Generic name
Tasimelteon
How it’s taken
By mouth
Reason
FDA exclusivity endsFDA gives new drugs a protected period, for example for a rare-disease use. It ends then.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
Sales not reported
Expected generic launchDec2027 About 14 months away

Zontivity

Generic name
Vorapaxar Sulfate
How it’s taken
By mouth
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported
Expected generic launchDec2027 About 15 months away

Cardene IV ready-to-use premixed injection, in dextrose

Generic name
Nicardipine Hydrochloride
How it’s taken
Into a vein (IV)
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
Low 1 company has filed
Brand sales
Sales not reported

Sometime in 2027, no month yet

25 expected
Expected generic launchJul to Sep2027 A 3-month window

Ibrance tablet

Generic name
Palbociclib
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 7 companies have filed, 1 first in line
Brand sales
$3.4B a yearBlockbuster
Expected generic launchApr to Jun2027 A 3-month window

Uptravi tablet

Generic name
Selexipag
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 6 companies have filed, 4 first in line
Brand sales
$1.8B a yearBlockbuster
Expected generic launchDuring2027 Sometime that year

Kyprolis

Generic name
Carfilzomib
How it’s taken
Into a vein (IV)
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 16 companies have filed, 10 first in line
Brand sales
$1.3B a yearBlockbuster
Expected generic launchJul to Sep2027 A 3-month window

Xtandi capsule

Generic name
Enzalutamide
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 8 companies have filed, 4 first in line
Brand sales
$1.2B a yearBlockbuster
Expected generic launch2027to 2028 A wide window

Inlyta

Generic name
Axitinib
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Very strong 6 companies have filed, 1 first in line
Brand sales
$869M a yearBig seller
Expected generic launchJul to Sep2027 A 3-month window

Ibrance capsule

Generic name
Palbociclib
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 15 companies have filed, 13 first in line
Brand sales
$644M a yearBig seller
Expected generic launch2027to 2028 A wide window

Mekinist tablet

Generic name
Trametinib Dimethyl Sulfoxide
How it’s taken
By mouth
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 3 companies have filed, 1 first in line
Brand sales
$640M a yearBig seller
Expected generic launchDuring2027 Sometime that year

Cresemba

Generic name
Isavuconazonium Sulfate
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Strong 5 companies have filed, 4 first in line
Brand sales
$461M a yearBig seller
Expected generic launch2027to 2028 A wide window

Invokana

Generic name
Canagliflozin
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 12 companies have filed, 10 first in line
Brand sales
$273M a yearBig seller
Expected generic launch2027to 2028 A wide window

Onureg

Generic name
Azacitidine
How it’s taken
By mouth
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Strong 4 companies have filed, 1 first in line
Brand sales
$160M a yearBig seller
Expected generic launch2027to 2028 A wide window

Gilotrif

Generic name
Afatinib Dimaleate
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 9 companies have filed, 7 first in line
Brand sales
$101M a yearBig seller
Expected generic launch2027to 2028 A wide window

Edarbyclor

Generic name
Azilsartan Kamedoxomil and Chlorthalidone
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Strong 5 companies have filed, 1 first in line
Brand sales
$62M a yearSmaller seller
Expected generic launch2027to 2028 A wide window

Enstilar

Generic name
Betamethasone Dipropionate and Calcipotriene
How it’s taken
On the skin
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$36M a yearSmaller seller
Expected generic launch2027to 2029 A wide window

Mekinist for oral solution

Generic name
Trametinib Dimethyl Sulfoxide
How it’s taken
By mouth
Reason
Not yet clearNo generic application is on record yet. The month follows the patents and protections on record, which a challenge or a deal can end early.
How sure
Probable More likely than not, but it can still move.
Price competition
None filed yet No filers on record
Brand sales
$34M a yearSmaller seller
Expected generic launch2027to 2028 A wide window

Emerphed

Generic name
Ephedrine Sulfate
How it’s taken
Into a vein (IV)
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Strong 4 companies have filed, 1 first in line
Brand sales
$29M a yearSmaller seller
Expected generic launch2027to 2028 A wide window

Relistor 12 mg/0.6 mL pre-filled syringe

Generic name
Methylnaltrexone Bromide
How it’s taken
Injection under the skin
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed
Brand sales
$28M a yearSmaller seller
Expected generic launch2027to 2028 A wide window

Savaysa

Generic name
Edoxaban Tosylate
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$9M a yearSmaller seller
Expected generic launch2027to 2028 A wide window

Relistor 8 mg/0.4 mL pre-filled syringe

Generic name
Methylnaltrexone Bromide
How it’s taken
Injection under the skin
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
$6M a yearSmaller seller
Expected generic launch2027to 2028 A wide window

Gloperba

Generic name
Colchicine
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
under $10M a yearSmall seller
Expected generic launch2027to 2028 A wide window

Qdolo

Generic name
Tramadol Hydrochloride
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
under $10M a yearSmall seller
Expected generic launch2027to 2028 A wide window

Thyquidity

Generic name
Levothyroxine Sodium
How it’s taken
By mouth
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$2M a yearSmaller seller
Expected generic launchJul to Dec2027 A 6-month window

Lumify PF

Generic name
Brimonidine Tartrate
How it’s taken
In the eye
Reason
Settlement expectedThe patent fight is likely to end in an agreement that sets the launch. The terms are not public yet.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported
Expected generic launch2027to 2028 A wide window

Invokamet XR

Generic name
Canagliflozin and Metformin Hydrochloride
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Strong 4 companies have filed, 1 first in line
Brand sales
Sales not reported
Expected generic launch2027to 2028 A wide window

Kybella

Generic name
Deoxycholic Acid
How it’s taken
Injection under the skin
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
Sales not reported
Expected generic launch2027to 2028 A wide window

Xartemis XR

Generic name
Acetaminophen and Oxycodone Hydrochloride
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
Sales not reported

January 2028

5 expected
Expected generic launchJan2028 About 15 months away

Xifaxan 550 mg

Generic name
Rifaximin
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Very strong 15 companies have filed, 1 first in line
Brand sales
$3.2B a yearBlockbuster
Expected generic launchJan2028 About 15 months away

Nayzilam

Generic name
Midazolam
How it’s taken
In the nose
Good to know
Hard to copy
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Strong 4 companies have filed, 1 first in line
Brand sales
$263M a yearBig seller
Expected generic launchJan2028 About 16 months away

Nourianz

Generic name
Istradefylline
How it’s taken
By mouth
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$24M a yearSmaller seller
Expected generic launchJan2028 About 15 months away

Xifaxan 200 mg

Generic name
Rifaximin
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Very strong 6 companies have filed, 1 first in line
Brand sales
$4M a yearSmaller seller
Expected generic launchJan2028 About 15 months away

Yutiq

Generic name
Fluocinolone Acetonide
How it’s taken
Injection into the eye
Good to know
Hard to copy
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported

February 2028

2 expected
Expected generic launchFeb2028 About 16 months away

Perseris Kit

Generic name
Risperidone
How it’s taken
Injection under the skin
Good to know
Hard to copy
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Probable More likely than not, but it can still move.
Price competition
None filed yet No filers on record
Brand sales
$40M a yearSmaller seller
Expected generic launchFeb2028 About 17 months away

Winlevi

Generic name
Clascoterone
How it’s taken
On the skin
Good to know
Hard to copy
Reason
Court hold endsWhen a generic maker challenges a patent, FDA must wait up to 30 months before approving it. That wait ends then.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
Sales not reported

March 2028

1 expected
Expected generic launchMar2028 About 17 months away

Zolinza

Generic name
Vorinostat
How it’s taken
By mouth
Good to know
Hard to copy
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported

April 2028

2 expected
Expected generic launchApr2028 About a year and a half away

Eliquis 5 mg tablet

Generic name
Apixaban
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 30 companies have filed, 25 first in line
Brand sales
$26.6B a yearBlockbuster
Expected generic launchApr2028 About a year and a half away

Eliquis 2.5 mg tablet

Generic name
Apixaban
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 30 companies have filed, 25 first in line
Brand sales
$6.1B a yearBlockbuster

Sometime in 2028, no month yet

19 expected
Expected generic launchDuring2028 Sometime that year

Xtandi tablet

Generic name
Enzalutamide
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Very strong 12 companies have filed, 1 first in line
Brand sales
$3.6B a yearBlockbuster
Expected generic launchDuring2028 Sometime that year

Tivicay

Generic name
Dolutegravir Sodium
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Very strong 14 companies have filed, 4 first in line
Brand sales
$1.6B a yearBlockbuster
Expected generic launchDuring2028 Sometime that year

Triumeq

Generic name
Abacavir Sulfate, Dolutegravir Sodium, and Lamivudine
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Very strong 9 companies have filed, 5 first in line
Brand sales
$1.4B a yearBlockbuster
Expected generic launch2028to 2029 A wide window

Nexplanon

Generic name
Etonogestrel
How it’s taken
Implant
Good to know
Hard to copy
Reason
Settlement expectedThe patent fight is likely to end in an agreement that sets the launch. The terms are not public yet.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$965M a yearBig seller
Expected generic launch2028to 2029 A wide window

Ninlaro

Generic name
Ixazomib Citrate
How it’s taken
By mouth
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$342M a yearBig seller
Expected generic launch2028to 2029 A wide window

Avycaz

Generic name
Ceftazidime and Avibactam Sodium
How it’s taken
Into a vein (IV)
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 2 first in line
Brand sales
$258M a yearBig seller
Expected generic launchDuring2028 Sometime that year

Kalydeco tablets

Generic name
Ivacaftor
How it’s taken
By mouth
Good to know
Hard to copy
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Strong 4 companies have filed, 1 first in line
Brand sales
$228M a yearBig seller
Expected generic launchDuring2028 Sometime that year

Nextstellis

Generic name
Drospirenone and Estetrol
How it’s taken
By mouth
Reason
Not yet clearNo generic application is on record yet. The month follows the patents and protections on record, which a challenge or a deal can end early.
How sure
Probable More likely than not, but it can still move.
Price competition
None filed yet No filers on record
Brand sales
$148M a yearBig seller
Expected generic launchJan to Jun2028 A 6-month window

Kalydeco granules

Generic name
Ivacaftor
How it’s taken
By mouth
Good to know
Hard to copy
Reason
Not yet clearOne generic maker has filed an application with FDA. What opens the door, a ruling, a deal or an expiry, is not settled yet.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$79M a yearSmaller seller
Expected generic launch2028to 2029 A wide window

Clenpiq

Generic name
Citric Acid, Magnesium Oxide, and Sodium Picosulfate
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
$75M a yearSmaller seller
Expected generic launch2028to 2029 A wide window

Dyanavel XR tablet

Generic name
Amphetamine, Amphetamine Aspartate / Dextroamphetamine Sulfate
How it’s taken
By mouth
Good to know
Hard to copy
Reason
Settlement expectedThe patent fight is likely to end in an agreement that sets the launch. The terms are not public yet.
How sure
Probable More likely than not, but it can still move.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$43M a yearSmaller seller
Expected generic launch2028to 2029 A wide window

Plenvu

Generic name
Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, and Sodium Sulfate
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
$38M a yearSmaller seller
Expected generic launchDuring2028 Sometime that year

Sodium Thiosulfate Injection

Generic name
Sodium Thiosulfate
How it’s taken
Into a vein (IV)
Good to know
Hard to copy
Reason
Settlement expectedThe patent fight is likely to end in an agreement that sets the launch. The terms are not public yet.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
$37M a yearSmaller seller
Expected generic launch2028to 2029 A wide window

Isentress HD 600 mg tablet

Generic name
Raltegravir Potassium
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Moderate 2 companies have filed, 1 first in line
Brand sales
$36M a yearSmaller seller
Expected generic launchJan to Jun2028 A 6-month window

Invokamet

Generic name
Canagliflozin and Metformin Hydrochloride
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Likely Firm enough to plan around, but a court ruling or a new deal could still move it.
Price competition
Very strong 7 companies have filed, 6 first in line
Brand sales
Sales not reported
Expected generic launchDuring2028 Sometime that year

Triumeq PD

Generic name
Abacavir Sulfate, Dolutegravir Sodium, and Lamivudine
How it’s taken
By mouth
Reason
Settlement expectedThe patent fight is likely to end in an agreement that sets the launch. The terms are not public yet.
How sure
Probable More likely than not, but it can still move.
Price competition
Strong 4 companies have filed, 1 first in line
Brand sales
Sales not reported
Expected generic launchDuring2028 Sometime that year

Utibron Neohaler

Generic name
Glycopyrrolate and Indacaterol Maleate
How it’s taken
Inhaled
Good to know
Hard to copy
Reason
Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported
Expected generic launchDuring2028 Sometime that year

Eliquis tablets for oral suspension

Generic name
Apixaban
How it’s taken
By mouth
Reason
Settlement expectedThe patent fight is likely to end in an agreement that sets the launch. The terms are not public yet.
How sure
Toss-up Still unsettled. Just as likely to slip as to hold.
Price competition
None filed yet No filers on record
Brand sales
Sales not reported
Expected generic launch2028to 2029 A wide window

Vyzulta

Generic name
Latanoprostene Bunod
How it’s taken
In the eye
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Probable More likely than not, but it can still move.
Price competition
Strong 4 companies have filed, 1 first in line
Brand sales
Sales not reported

No date yet

4 waiting
Expected generic launchTBDno date yet

Isentress 400 mg tablet

Generic name
Raltegravir Potassium
How it’s taken
By mouth
Reason
Settlement between companiesThe brand company and a generic maker settled their patent fight and agreed on when a generic can launch.
How sure
Not rated Too early to rate.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$227M a yearBig seller
Expected generic launchTBDno date yet

Primatene Mist

Generic name
Epinephrine
How it’s taken
Inhaled
Good to know
Hard to copy
Reason
Awaiting FDA approvalThe patents are not the problem. A generic still needs FDA sign-off, and that is when it is expected.
How sure
Not rated Too early to rate.
Price competition
None filed yet No filers on record
Brand sales
$194M a yearBig seller
Expected generic launchTBDno date yet

Neupro

Generic name
Rotigotine
How it’s taken
Skin patch
Good to know
Hard to copy
Reason
Awaiting FDA approvalThe patents are not the problem. A generic still needs FDA sign-off, and that is when it is expected.
How sure
Very likely Few things could still move it, but a court ruling or a new deal can.
Price competition
Strong 4 companies have filed, 1 first in line
Brand sales
$119M a yearBig seller
Expected generic launchTBDno date yet

Norepinephrine Bitartrate in Sodium Chloride Injection InfoRLife

Generic name
Norepinephrine Bitartrate
How it’s taken
Into a vein (IV)
Reason
Not yet clearOne generic maker has filed an application with FDA. What opens the door, a ruling, a deal or an expiry, is not settled yet.
How sure
Not rated Too early to rate.
Price competition
Low 1 company has filed, 1 first in line
Brand sales
$102M a yearBig seller

This list shows the next 18 months and a few drugs with no date yet. Every other drug on the schedule is in the A to Z list below.

Every Drug on the Schedule, A to Z

Every brand-name drug we follow, with the month or window its first generic is expected. Pick a letter; each drug opens its own launch page, and a drug that has left the schedule keeps its page. Not seeing yours? Some drugs are years away from a generic, and a few are too small to track: ask a pharmacist and we will look it up.

A

Show all 73 drugs starting with AShow fewer
  • Agamree Vamorolone April 2034
  • AirDuo Digihaler Fluticasone Propionate and Salmeterol January 2041
  • Airsupra Albuterol Sulfate and Budesonide May 2030
  • Akeega Abiraterone Acetate and Niraparib Tosylate July 2037
  • Aklief Trifarotene 2031 to 2032
  • Akten Lidocaine Hydrochloride No date yet
  • Akynzeo Netupitant and Palonosetron Hydrochloride September 2031
  • Alecensa Alectinib Hydrochloride 2032 to 2033
  • Aliqopa Copanlisib Dihydrochloride March 2032
  • Alkindi Sprinkle Hydrocortisone January 2033
  • Altabax Retapamulin February 2027
  • Altreno Tretinoin August 2038
  • Alunbrig Brigatinib April 2034
  • Alvaiz Eltrombopag Choline October 2038
  • Alyftrek Deutivacaftor, Tezacaftor, and Vanzacaftor Calcium February 2039
  • Ambelvist Gadoquatrane 2039 to 2040
  • Ameluz Aminolevulinic Acid Hydrochloride December 2043
  • Amondys Casimersen November 2030
  • Amvuttra Vutrisiran Sodium July 2036
  • Amyvid Florbetapir F 18 April 2027
  • Amzeeq Minocycline Hydrochloride July 2031
  • Angeliq Drospirenone and Estradiol No date yet
  • Anjeso Meloxicam March 2039
  • Annovera Ethinyl Estradiol and Segesterone Acetate June 2039
  • Anzupgo Delgocitinib September 2036
  • Aphexda Motixafortide Acetate September 2030
  • Aplenzin Bupropion Hydrobromide Jul to Dec 2026
  • Aponvie Aprepitant June 2032
  • Apretude Cabotegravir September 2031
  • Aqneursa Levacetylleucine April 2037
  • Aqvesme Mitapivat Sulfate 2038 to 2039
  • Arazlo Tazarotene 2029 to 2030
  • Arbli Losartan Potassium October 2041
  • Arcapta Neohaler Indacaterol Maleate October 2028
  • Arikayce Amikacin Sulfate May 2035
  • Aristada Aripiprazole Lauroxil April 2039
  • Aristada Initio Aripiprazole Lauroxil April 2039
  • Artesunate Artesunate February 2044
  • Arymo ER Morphine Sulfate 2026 to 2027
  • Arynta Lisdexamfetamine Dimesylate August 2040
  • Astepro Azelastine Hydrochloride No date yet
  • Atebrioz Zilurgisertib September 2040
  • Atorvaliq Atorvastatin Calcium No date yet
  • Attruby Acoramidis Hydrochloride March 2039
  • Atzumi Dihydroergotamine December 2039
  • Augtyro Repotrectinib November 2037
  • Aurlumyn Iloprost February 2031
  • Austedo Deutetrabenazine April 2033
  • Austedo XR Deutetrabenazine 2036 to 2037
  • Auvelity Bupropion Hydrochloride and Dextromethorphan Hydrobromide September 2038
  • Auvi-Q Epinephrine December 2037
  • Avaclyr Acyclovir No date yet
  • Aveed Testosterone Undecanoate May 2027
  • Avmapki Fakzynja Co-Pack Avutometinib and Defactinib 2038 to 2039
  • Avycaz Ceftazidime and Avibactam Sodium 2028 to 2029
  • Ayvakit Avapritinib 2035 to 2036
  • Azmiro Testosterone Cypionate March 2039
  • Azstarys Dexmethylphenidate Hydrochloride and Serdexmethylphenidate Chloride December 2037

How We Build Our Data

Every date on the tracker comes from public records, read together. A patent list alone gives the date many websites show, but the first generic often arrives sooner, because of a settlement or a court ruling. We weigh all of it and update the schedule every month. We give a month, not an exact day: even when the legal date is known, it takes days to weeks for a new generic to reach pharmacies.

  • FDA Orange BookThe FDA’s list of the patents and other protections on each brand-name drug, and the date each one ends.Many websites show the last of these dates. The first generic often arrives sooner.
  • Drugs@FDAThe FDA’s record of every drug it has approved, including generics it has cleared that cannot be sold yet.When a generic is already approved, it can launch as soon as the patents allow.
  • FDA Paragraph IV listThe FDA’s list of brand-name drugs whose patents a generic company has challenged, and when.The first company to challenge can earn a six-month head start on other generic companies.
  • Federal court recordsPatent lawsuits between brand-name and generic drug companies, and what the judges decided.A court decision can let a generic launch early or push the date back.
  • Company announcements and securities filingsWhat drug companies say publicly: settlement dates and launch plans.Many dates on the tracker come from settlements the companies announced; about half follow the end of a patent.
  • FDA NDC Directory and NADACWhich versions of a drug are for sale, who makes them, and what pharmacies pay for them.Once a generic launches, this is where its real price shows up.

How We Estimate the Month

  1. We start with the patents. The day the last one ends is the date many websites show, and usually the longest a generic would have to wait.
  2. We check for patent challenges. When a generic company challenges a patent, the brand usually sues, and the FDA has to wait up to 30 months before approving the generic.
  3. We look for a settlement or a court ruling. Most of these fights end with the two companies agreeing on a launch date, or with a judge deciding the case.
  4. We see who is ready to launch. Generics the FDA has already approved, and how many companies have applied, tell us how many could launch at once. The more companies, the lower the price tends to fall.
  5. We rate how sure we are. A date from a public settlement is very likely. A date that depends on a court case still going on is a toss-up.

Our month is only an estimate based on available information. A brand can win a court case and push the date back, settle for an earlier date, or sell its own lower-cost copy (an “authorized generic”). Every drug’s page keeps a log of each change we see.

Updated October 9, 2026. Information, not medical advice: never stop or switch a drug without talking to your prescriber or pharmacist.

Generic Drug Questions People Ask

Which drugs are going generic soon?

The next brand-name drugs expected to get a first generic are Adasuve (October 2026), Synribo (October 2026), Horizant (November 2026), Trintellix (December 2026) and Signifor (December 2026). The list on this page shows every drug due in the next 6 months, month by month, and the Show buttons look further ahead. The A to Z list names every drug on the schedule with its expected month or window, and each drug opens its own page with the patents, approvals and prices behind its month.

Will the generic cost less right away?

Usually, but how much depends on how many companies launch. FDA’s own analysis of past launches found that one generic maker brought prices about 39% under the brand, two about 54%, four about 79%, and six or more over 95%. Big sellers draw more makers, which is why every row shows the brand’s yearly sales and how many companies have filed (the Price competition column).

Why do other websites show a different date?

Many list the day the last patent expires. Generics often arrive earlier than that, through settlements or successful patent challenges, and sometimes later, when nobody is ready to launch. Each drug’s page shows its last patent beside the month we expect, so you can see the gap.

Why only a month and not a day?

Because a day would promise more than anyone knows. Legal dates move, and even when they hold, the first generic reaches pharmacy shelves days to weeks later. The month is the honest answer, and “Coming soon” means it is within about three months.

Is a generic really the same as the brand?

Yes in the ways that matter: the same active ingredient, strength and form, and proof that it reaches your blood the same way. Inactive ingredients can differ, which is why a generic may look or taste different.

My drug is not here. Will it ever go generic?

Probably, but it may be many years away, or it may be a biologic, which gets a “biosimilar” instead of a generic. Ask us and a pharmacist will check the records for you.