Perseris Generic: When Will Generic Risperidone Be Available?
This page is aggregated from FDA records, court filings and company announcements. Coded and designed by Dr. Brian Staiger, PharmD, BCPS
Updated October 9, 2026 How we build our data
Perseris Generic at a Glance
Four quick answers from FDA records and our estimate.
- When is the first generic expected? February 2028 About 16 months away Why then?
- Has the FDA approved a generic? Unknown No FDA Orange Book record under this name
- When does the brand’s protection end? Unknown Not in the FDA record we could read
- Can you buy a generic today? Yes 3 companies list one
It already is. A generic risperidone is listed for sale by 3 companies, so ask your pharmacy whether it can fill your prescription with one.
Why February 2028?
A patent that protects the brand runs out. After that, approved generics can be sold. We rate it probable: more likely than not, but it can still move.
What should I do now?
Ask your pharmacy whether it can fill your prescription with a generic. It may look different from Perseris, but the active ingredient, strength and form are the same. What a generic means for you
Our month is only an estimate based on available information, so we never name a day.
Perseris by the Numbers
- Reason
- Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
- How sure
- Probable More likely than not, but it can still move.
- Price competition
- None filed yet No filers on record
- Brand sales
- $40M a yearSmaller seller
- Pharmacies pay $2,081.29 each, up 0.8% in a year NADAC, October 2026
- Medicare Part D spent $21.5M in 2025, for 1,248 people CMS Part D Spending by Drug
- Medicaid prescriptions 6,511 in the last four reported quarters, $16.5M CMS Medicaid drug utilization, to Q1 2026
Perseris’s Road to a Generic
The first generic of Perseris is expected in February 2028.
Why that month: a patent that protects the brand runs out. After that, approved generics can be sold.
The bar shows Perseris on the market on its own until the month we expect the first generic (the green band), a month and never a day. Its approval date and patents are not in the FDA Orange Book under this name, so the bar fades in from the left. The expected month comes from court records and company announcements.
Who Is Lined Up to Make Generic Risperidone
Three steps stand between a brand and a generic you can buy: a company applies to the FDA, the FDA approves it, and the company starts selling it.
Applied to the FDA
No company is recorded as having applied to the FDA to make a generic Perseris yet.
Approved by the FDA
We could not find Perseris’s own record in the FDA Orange Book under this name, so the approved generic makers are not shown.
For Sale in Pharmacies
Yes. A generic risperidone is listed for sale by 3 companies. Ask your pharmacy whether it can fill your prescription with it.
Amneal Pharmaceuticals LLC, Lupin Pharmaceuticals, Inc. and Teva Pharmaceuticals, Inc.
Sources: how many companies have applied, from court records and company announcements; approved generics from the FDA Orange Book; what is for sale from the FDA NDC Directory. The FDA does not disclose an application before it approves it (21 CFR 314.430).
Perseris Price: What Pharmacies Pay and What Generics Usually Do
What Pharmacies Pay for Perseris ER 90 mg syringe kit
$2,081.29 each in October 2026, up 0.8% from a year earlier.
Hover over or tap anywhere on the chart to see that month’s price.
- Perseris ER 90 mg syringe kit $2,081.29 each
- Perseris ER 120 mg syringe kit $2,764.71 each
See the numbers
| Month | Pharmacies paid each |
|---|---|
| October 2026 | $2,081.29 |
| September 2026 | $2,081.29 |
| August 2026 | $2,086.22 |
| July 2026 | $2,085.68 |
| June 2026 | $2,080.08 |
| May 2026 | $2,076.11 |
| April 2026 | $2,073.86 |
| March 2026 | $2,071.98 |
| February 2026 | $2,078.56 |
| January 2026 | $2,084.04 |
| February 2024 | $2,064.63 |
| January 2024 | $2,064.63 |
NADAC: the national average price retail pharmacies pay to buy the medicine (CMS survey, updated weekly), the last price of each month for one package. It is not what you pay: that depends on your insurance or discount card.
What a Generic Could Cost
How we estimate it. We start from what pharmacies pay for Perseris today: $2,081.29 each for Perseris ER 90 mg syringe kit in October 2026, from the national NADAC survey. Then we apply the FDA’s finding of how far that price usually falls as generic companies join: about 31% with one company, 44% with two, 73% with four and over 95% with six or more (the typical drop for every drug whose first generic came out from 2015 to 2017).
Dollar figures apply FDA’s median drops to the $2,081.29 pharmacies pay each today. An estimate from the pattern, not a price quote: what you pay depends on your insurance or discount card.
Median prices pharmacies paid for the generic (invoice prices), compared with the brand’s price before generic entry, from FDA’s 2019 analysis “Generic Competition and Drug Prices”. At the manufacturer’s price FDA found steeper drops (about 39%, 54%, 79% and over 95%), the figures quoted elsewhere on this tracker. A typical pattern, not a price quote for this medicine.
What Medicare and Medicaid Spend on Perseris
Big public spending is part of why generic makers line up for a medicine, and why its first generic matters beyond the pharmacy counter. Figures are before manufacturer rebates, which are confidential.
Medicare Part D Spending
What Medicare drug plans spent on Perseris, before manufacturer rebates.
- $3.3M
- January to March 2026, the latest CMS has posted
For 515 people, about $2,693 per prescription fill - $21.5M
- 2025, the whole year
For 1,248 people, about $2,749 per prescription fill
See the numbers
| Period | Spending | People | Per fill |
|---|---|---|---|
| January to March 2026 | $3,296,198 | 515 | $2,692.97 |
| 2025 | $21,463,521 | 1,248 | $2,749.27 |
Source: CMS Medicare Part D Spending by Drug, matched by the brand name Perseris only, so no generic is counted in it. What CMS says it is used for: This medication is used to treat certain mental/mood disorders (such as schizophrenia, bipolar disorder). Risperidone belongs to a class of drugs known as atypical antipsychotics.
Medicaid Prescriptions by Quarter
6,511 prescriptions in the four quarters to Q1 2026, $16.5M paid.
See the numbers
| Quarter | Prescriptions | Medicaid paid |
|---|---|---|
| Q1 2026 | 1,079 | $2,760,826 |
| Q4 2025 | 1,494 | $3,804,776 |
| Q3 2025 | 1,823 | $4,587,099 |
| Q2 2025 | 2,115 | $5,304,586 |
| Q1 2025 | 2,561 | $6,483,988 |
Source: CMS Medicaid State Drug Utilization Data, over Perseris’s own package codes.
Perseris NDC Codes and Packages
Each Perseris package sold today has its own NDC, the product number printed on the box and on the pharmacy label. Open one to see that package’s details, what pharmacies pay for it and its patent timeline.
| NDC | Product | Package | Company |
|---|---|---|---|
| 12496-0090-01 | kit | 1 KIT in 1 CARTON * 1 SYRINGE in 1 POUCH / 1.2 mL in 1 SYRINGE * 1 SYRINGE in 1 POUCH / 1 mL in 1 SYRINGE | Indivior Inc. |
| 12496-0090-01 | kit | 1 KIT in 1 CARTON * 1 SYRINGE in 1 POUCH / 1.2 mL in 1 SYRINGE * 1 SYRINGE in 1 POUCH / 1 mL in 1 SYRINGE | Indivior Inc. |
| 12496-0090-09 | kit | 1 KIT in 1 CARTON * 1 SYRINGE in 1 POUCH / 1.2 mL in 1 SYRINGE * 1 SYRINGE in 1 POUCH / 1 mL in 1 SYRINGE | Indivior Inc. |
| 12496-0090-09 | kit | 1 KIT in 1 CARTON * 1 SYRINGE in 1 POUCH / 1.2 mL in 1 SYRINGE * 1 SYRINGE in 1 POUCH / 1 mL in 1 SYRINGE | Indivior Inc. |
| 12496-0120-01 | kit | 1 KIT in 1 CARTON * 1 SYRINGE in 1 POUCH / 1.2 mL in 1 SYRINGE * 1 SYRINGE in 1 POUCH / 1 mL in 1 SYRINGE | Indivior Inc. |
| 12496-0120-01 | kit | 1 KIT in 1 CARTON * 1 SYRINGE in 1 POUCH / 1.2 mL in 1 SYRINGE * 1 SYRINGE in 1 POUCH / 1 mL in 1 SYRINGE | Indivior Inc. |
| 12496-0120-09 | kit | 1 KIT in 1 CARTON * 1 SYRINGE in 1 POUCH / 1.2 mL in 1 SYRINGE * 1 SYRINGE in 1 POUCH / 1 mL in 1 SYRINGE | Indivior Inc. |
| 12496-0120-09 | kit | 1 KIT in 1 CARTON * 1 SYRINGE in 1 POUCH / 1.2 mL in 1 SYRINGE * 1 SYRINGE in 1 POUCH / 1 mL in 1 SYRINGE | Indivior Inc. |
Source: the FDA NDC Directory, current listings only. Some codes belong to companies that repackage Perseris: it is the same medicine in a different package.
What a Generic Perseris Means for You
Nothing Changes Until It Is in Pharmacies
A generic is listed for sale now, so your pharmacy may already be able to fill your prescription with it.
Your Pharmacy May Switch You Automatically
Every state lets pharmacists fill a brand-name prescription with an FDA-approved generic rated as equivalent to it, and about 19 states require them to, unless your prescriber writes “dispense as written” or “brand medically necessary” on the prescription. Some states ask the pharmacist to tell you, or to get your OK first. A study of every state’s law has the details.
It Will Probably Look Different
US trademark law does not let a generic look exactly like the brand, so the color, shape or markings usually change. The active ingredient, strength and form are the same. An “authorized generic,” made by or for the brand’s own company, can look identical. The FDA explains.
Your Insurance May Change Too
Once a lower-cost version is available, many insurance plans charge more for the brand, or stop covering it. Your plan’s drug list (formulary) says how.
Questions people ask about Perseris
Is there a generic for Perseris right now?
Yes. The FDA NDC Directory lists a generic risperidone from 3 companies. Ask your pharmacy whether it can fill your prescription with it.
When will Perseris go generic?
It already has. The FDA NDC Directory lists a generic risperidone from 3 companies, so ask your pharmacy whether it can fill your prescription with one.
Will generic risperidone be the same as Perseris?
Yes in the ways that matter: the same active ingredient, strength and form, with proof that it reaches your blood the same way. Inactive ingredients can differ, which is why some people notice a different look or taste.
How much will the generic cost?
Nobody can say for sure before launch. No company is recorded as having applied to the FDA to make one yet, and a single company usually brings only a modest drop.
How much does Perseris cost now?
Pharmacies paid about $2,081.29 each for Perseris ER 90 mg syringe kit in October 2026, by the national survey of what pharmacies pay (NADAC). That is the pharmacy’s cost, not your price: what you pay depends on your insurance or discount card.
Changes to This Projection
- First generic expected February 2028 on this month’s schedule. A line is added here whenever a monthly update moves the month, the reason or how sure it is.
Every change to the expected month is logged here with the month we saw it.
Also Going Generic
- AkliefTrifarotene2031 to 2032
- NithiodoteSodium Thiosulfate and Sodium NitriteDecember 2031
- InluriyoImlunestrantSeptember 2039
- DetectnetCopper Cu-64 DotatateSeptember 2041
- RyaltrisMometasone Furoate and Olopatadine HydrochlorideNovember 2044
- VeregenSinecatechinsTBD no date yet
About Perseris
- Generic name risperidone
- How it is taken Injection under the skin
- Hard to copy Inhalers, injectables, patches and other hard-to-copy products. Fewer companies attempt them and dates slip more often.
- More drugs Brand-name drugs starting with P
- Have a question? A pharmacist answers, free. Ask about Perseris
Sources. The expected month: FDA Paragraph IV Patent Certifications list, federal court records, company announcements and securities filings (settlement dates, launch plans, sales). The record on this page: FDA Orange Book, FDA NDC Directory, NADAC (CMS), CMS Medicare Part D Spending by Drug, Medicaid State Drug Utilization Data, FDA, Generic Competition and Drug Prices (2019). Updated October 9, 2026. Information, not medical advice.