Brand-Name Drugs Starting With S
The month or window each one is expected to get its first, lower-cost generic. Each drug opens its own launch page with the patents, approvals and prices behind its month.
This list is aggregated from FDA records, court filings and company announcements. Coded and designed by Dr. Brian Staiger, PharmD, BCPS
Updated October 9, 2026 How we build our data
S
- Salonpas Menthol and Methyl Salicylate January 2030
- Savaysa Edoxaban Tosylate 2027 to 2028
- Scemblix Asciminib Hydrochloride 2035 to 2036
- Scenesse Afamelanotide January 2033
- Secuado Asenapine July 2033
- Seglentis Celecoxib and Tramadol Hydrochloride April 2030
- Segluromet Ertugliflozin and Metformin Hydrochloride December 2031
- Selenious Acid Selenious Acid No date yet
- Sephience Sepiapterin 2037 to 2038
- Sernivo Betamethasone Dipropionate Sometime in 2026
- Seysara Sarecycline Hydrochloride February 2033
- Sezaby Phenobarbital Sodium November 2029
- Signifor Pasireotide Diaspartate December 2026
- Signifor LAR Pasireotide Pamoate May 2028
- Siklos Hydroxyurea No date yet
- Simbrinza Brimonidine Tartrate and Brinzolamide Sometime in 2026
- Simtriyo Centanafadine 2037 to 2038
- Sirturo Bedaquiline Fumarate March 2029
- Sitavig Acyclovir June 2030
- Sivextro Tedizolid Phosphate December 2030
- Skyclarys Omaveloxolone February 2037
- Skyla Levonorgestrel September 2029
- Slynd Drospirenone Jan to Jun 2031
- Sodium Thiosulfate Sodium Thiosulfate Sometime in 2028
- Sofdra Sofpironium Bromide June 2038
- Sohonos Palovarotene August 2037
- Solosec Secnidazole September 2027
- Sotalol Hydrochloride IV Sotalol Hydrochloride No date yet
- Sotyktu Deucravacitinib September 2036
- Sotylize Sotalol Hydrochloride November 2034
- Sovaldi Sofosbuvir September 2029
- Spinraza Nusinersen 2033 to 2034
- Spiriva Respimat Tiotropium Bromide Monohydrate April 2031
- Spravato Esketamine Hydrochloride 2031 to 2032
- Spy Agent Green Indocyanine Green 2030 to 2031
- Steglatro Ertugliflozin Oct to Dec 2031
- Steglujan Ertugliflozin and Sitagliptin Phosphate December 2031
- Stiolto Respimat Olodaterol and Tiotropium October 2030
- Stivarga Regorafenib Jan to Mar 2031
- Stribild Cobicistat, Elvitegravir, Emtricitabine, and Tenofovir Disoproxil Fumarate 2029 to 2030
- Striverdi Respimat Olodaterol Hydrochloride October 2030
- Sublocade Buprenorphine November 2035
- Subsys Fentanyl No date yet
- Subvenite Lamotrigine May 2040
- Suflave Magnesium Sulfate, Polyethylene Glycol 3350, Potassium Chloride, Sodium Chloride, and Sodium Sulfate June 2044
- Sunlenca Lenacapavir Sodium 2041 to 2042
- Sunosi Solriamfetol Hydrochloride Sometime in 2040
- Suprenza Phentermine Hydrochloride No date yet
- Sutab Magnesium Sulfate, Potassium Chloride, and Sodium Sulfate 2033 to 2034
- Syfovre Pegcetacoplan 2035 to 2036
- Symbravo Meloxicam and Rizatriptan May 2040
- Symdeko Ivacaftor and Tezacaftor July 2031
- Sympazan Clobazam January 2040
- Symproic Naldemedine Tosylate February 2031
- Symtuza Cobicistat, Darunavir, Emtricitabine, and Tenofovir Alafenamide Sometime in 2032
- Syndros Dronabinol No date yet
- Synjardy Empagliflozin and Metformin 2032 to 2033
- Synjardy XR Empagliflozin and Metformin 2032 to 2033
- Synribo Omacetaxine Mepesuccinate October 2026
See every expected first generic month by month on Generic Launches. Not seeing yours? Ask a pharmacist and we will look it up.