Brand-Name Drugs Starting With L
The month or window each one is expected to get its first, lower-cost generic. Each drug opens its own launch page with the patents, approvals and prices behind its month.
This list is aggregated from FDA records, court filings and company announcements. Coded and designed by Dr. Brian Staiger, PharmD, BCPS
Updated October 9, 2026 How we build our data
L
- Lampit Nifurtimox August 2027
- Lastacaft Alcaftadine 2026 to 2027
- Lazanda Fentanyl Citrate No date yet
- Lazcluze Lazertinib Mesylate August 2041
- Lenvima Lenvatinib Mesylate July 2030
- Leqselvi Deuruxolitinib July 2038
- Leqvio Inclisiran Sometime in 2036
- Levothyroxine Sodium Levothyroxine Sodium July 2036
- Libervant Diazepam April 2031
- Lifyorli Relacorilant 2039 to 2040
- Likmez Metronidazole 2030 to 2031
- Liletta Levonorgestrel September 2040
- Linzess Linaclotide March 2029
- Lipfendra Enlicitide Decanoate 2040 to 2041
- Lisraya Brepocitinib Tosylate Sometime in 2042
- Litfulo Ritlecitinib Tosylate June 2037
- Livdelzi Seladelpar Lysine March 2038
- Livmarli Maralixibat Chloride Jan to Jun 2032
- Livtencity Maribavir November 2042
- Lodoco Colchicine November 2033
- Lokelma Sodium Zirconium Cyclosilicate Sometime in 2034
- Lo Loestrin Fe Ethinyl Estradiol and Norethindrone Acetate Jan to Mar 2029
- Lonhala Magnair Glycopyrrolate December 2036
- Lonsurf Tipiracil Hydrochloride and Trifluridine 2032 to 2033
- Lorbrena Lorlatinib March 2033
- Loreev XR Lorazepam January 2034
- Lotemax SM Loteprednol Etabonate 2031 to 2032
- Lumakras Sotorasib August 2040
- Lumason Sulfur Hexafluoride Lipid-Type A Microspheres May 2039
- Lumify Brimonidine Tartrate June 2027
- Lumify PF Brimonidine Tartrate Jul to Dec 2027
- Lumryz Sodium Oxybate 2039 to 2040
- Lupkynis Voclosporin 2033 to 2034
- Lutathera Lutetium Lu 177 Dotatate 2026 to 2027
- Lybalvi Olanzapine and Samidorphan L-malate May 2033
- Lymphoseek Technetium TC-99M Tilmanocept January 2029
- Lynavoy Linerixibat October 2041
- Lynkuet Elinzanetant 2042 to 2043
- Lynparza Olaparib 2029 to 2030
- Lyrfigtu Lirafugratinib September 2040
- Lyvispah Baclofen July 2039
See every expected first generic month by month on Generic Launches. Not seeing yours? Ask a pharmacist and we will look it up.