Alvaiz Generic: When Will Generic Eltrombopag Choline Be Available?
This page is aggregated from FDA records, court filings and company announcements. Coded and designed by Dr. Brian Staiger, PharmD, BCPS
Updated October 9, 2026 How we build our data
Alvaiz Generic at a Glance
Four quick answers from FDA records and our estimate.
- When is the first generic expected? October 2038 About 12 years away Why then?
- Has the FDA approved a generic? Not yet None in the FDA’s records yet Why not yet?
- When does the last patent end? November 2038 Its only patent listed with the FDA Why is a generic expected sooner?
- Can you buy a generic today? Not yet No company lists one for sale
Generic eltrombopag choline is expected to be available in October 2038, about 12 years away. None is for sale yet.
Why October 2038?
It is when Alvaiz’s patent 11,072,586 ends. That patent covers the active ingredient, the product’s formulation and a way of using it, and once it ends, generics should be able to go on sale as soon as the FDA approves them. We rate it probable: more likely than not, but it can still move.
If Alvaiz’s last patent runs to November 2038, how can a generic come sooner?
The patent that runs to November 2038 (11,072,586) covers the active ingredient, the product’s formulation and a way of using it. A generic can still come sooner if a court rules a patent invalid or not infringed, or if the companies settle on an earlier date. That is why the expected month comes before the last protection ends. See the road to a generic
Why hasn’t the FDA approved a generic yet?
That is normal before a launch. The FDA usually can’t give a generic its final approval while a patent or exclusivity still blocks it, so final approval often comes close to the day the generic can be sold. No company holds a “tentative” approval yet either (the FDA’s word for a generic that is ready but still blocked).
Will the generic cost less?
Usually, but no company is recorded as having applied to make one yet, and a single company usually brings only a modest drop. See the price pattern
What should I do now?
Keep taking Alvaiz as prescribed. When a generic arrives, your pharmacy may switch you to it automatically, and it may look different. What a generic means for you
Our month is only an estimate based on available information, so we never name a day.
Alvaiz by the Numbers
- Reason
- Patent expiresA patent that protects the brand runs out. After that, approved generics can be sold.
- How sure
- Probable More likely than not, but it can still move.
- Price competition
- None filed yet No filers on record
- Brand sales
- $113M a yearBig seller
- FDA approved 2023 November 2023 FDA Orange Book
- Patents listed 1 last runs to November 2038 A generic is expected sooner, in October 2038. See why FDA Orange Book
- Medicare Part D spent $37.7M in 2025, for 741 people CMS Part D Spending by Drug
- Medicaid prescriptions 187 in the last four reported quarters, $2.6M CMS Medicaid drug utilization, to Q1 2026
Alvaiz’s Road to a Generic
Alvaiz has had the market to itself since the FDA approved it in November 2023 (Teva Pharmaceuticals Inc). Its one listed patent runs to November 2038.
The first generic of Alvaiz is expected in October 2038.
Why that month: patent 11,072,586, on the active ingredient, the product’s formulation and a way of using it, ends then. That is a few months before the last listed patent runs out, in November 2038.
Why a Generic Can Come Before November 2038
The last listed patent runs to November 2038; a court ruling or a settlement can bring a generic sooner. Dr. Brian explains
Each bar runs from the brand’s approval to the day that protection ends. The green band is our projection for the first generic: a month, never a day, because legal dates move and a generic reaches shelves days to weeks after it is allowed. Sources: FDA Orange Book; the expected month from court records and company announcements.
Alvaiz Patents and FDA Protections
Every patent and exclusivity the FDA Orange Book lists for Alvaiz’s own applications. A protection running past the expected month does not mean the date is wrong: a settlement or a court ruling can let a generic in before a patent ends, and a patent on one formulation or use does not block every generic.
The one that matters for a generic launch: patent 11,072,586, which ends in November 2038. Why the later ones may not hold it back
| Patent | What it covers | Protects until | Status |
|---|---|---|---|
| 11,072,586 Sets the expected month of generic availability | The active ingredient; the product’s formulation; a way of using it (U-3936, U-3937, U-3938) | November 2038 | Active |
Source: FDA Orange Book, application 216774. Patent numbers open the patent on Google Patents.
Who Is Lined Up to Make Generic Eltrombopag Choline
Three steps stand between a brand and a generic you can buy: a company applies to the FDA, the FDA approves it, and the company starts selling it.
Applied to the FDA
No company is recorded as having applied to the FDA to make a generic Alvaiz yet.
Approved by the FDA
Not yet. The FDA has not approved a generic eltrombopag choline. Final approval often comes close to the day a generic can be sold.
For Sale in Pharmacies
Not yet. No company lists a generic eltrombopag choline for sale with the FDA.
Sources: how many companies have applied, from court records and company announcements; approved generics from the FDA Orange Book; tentative approvals from Drugs@FDA; what is for sale from the FDA NDC Directory. The FDA does not disclose an application before it approves it (21 CFR 314.430).
Alvaiz Price: What Pharmacies Pay and What Generics Usually Do
What a Generic Could Cost
How we estimate it. The national survey of what pharmacies pay (NADAC) has no recent price for Alvaiz, so we cannot show dollars. Here is the FDA’s finding of how far the price pharmacies pay usually falls as generic companies join: about 31% with one company, 44% with two, 73% with four and over 95% with six or more (the typical drop for every drug whose first generic came out from 2015 to 2017).
Median prices pharmacies paid for the generic (invoice prices), compared with the brand’s price before generic entry, from FDA’s 2019 analysis “Generic Competition and Drug Prices”. At the manufacturer’s price FDA found steeper drops (about 39%, 54%, 79% and over 95%), the figures quoted elsewhere on this tracker. A typical pattern, not a price quote for this medicine.
What Medicare and Medicaid Spend on Alvaiz
Big public spending is part of why generic makers line up for a medicine, and why its first generic matters beyond the pharmacy counter. Figures are before manufacturer rebates, which are confidential.
Medicare Part D Spending
What Medicare drug plans spent on Alvaiz, before manufacturer rebates.
- $13M
- January to March 2026, the latest CMS has posted
For 629 people, about $8,782 per prescription fill - $37.7M
- 2025, the whole year
For 741 people, about $8,967 per prescription fill
See the numbers
| Period | Spending | People | Per fill |
|---|---|---|---|
| January to March 2026 | $12,953,649 | 629 | $8,782.13 |
| 2025 | $37,669,717 | 741 | $8,966.85 |
Source: CMS Medicare Part D Spending by Drug, matched by the brand name Alvaiz only, so no generic is counted in it. What CMS says it is used for: This medication is used to treat low platelet levels in people who have a certain blood disorder called chronic immune (idiopathic) thrombocytopenia purpura (ITP) or who have chronic hepatitis C. It may also be used to treat people with a certain blood disorder (aplastic anemia).
Medicaid Prescriptions by Quarter
187 prescriptions in the four quarters to Q1 2026, $2.6M paid.
See the numbers
| Quarter | Prescriptions | Medicaid paid |
|---|---|---|
| Q1 2026 | 30 | $478,841 |
| Q4 2025 | 59 | $773,249 |
| Q3 2025 | 51 | $702,019 |
| Q2 2025 | 47 | $688,793 |
| Q1 2025 | 53 | $736,235 |
Source: CMS Medicaid State Drug Utilization Data, over Alvaiz’s own package codes.
Alvaiz Strengths and Forms
| Strength | Form | How it is taken | Approved | Status |
|---|---|---|---|---|
| EQ 18MG BASE | Tablet | Oral | November 2023 | Prescription reference product |
| EQ 36MG BASE | Tablet | Oral | November 2023 | Prescription reference product |
| EQ 54MG BASE | Tablet | Oral | November 2023 | Prescription reference product |
| EQ 9MG BASE | Tablet | Oral | November 2023 | Prescription reference product |
Source: FDA Orange Book, Teva Pharmaceuticals Inc. Listed for sale today by Teva Pharmaceuticals, Inc. (FDA NDC Directory).
Alvaiz NDC Codes and Packages
Each Alvaiz package sold today has its own NDC, the product number printed on the box and on the pharmacy label. Open one to see that package’s details, what pharmacies pay for it and its patent timeline.
| NDC | Product | Package | Company |
|---|---|---|---|
| 00480-3274-56 | ELTROMBOPAG CHOLINE 18 mg/1 tablet, film coated | bottle of 30 tablets | Teva Pharmaceuticals, Inc. |
| 00480-3275-56 | ELTROMBOPAG CHOLINE 36 mg/1 tablet, film coated | bottle of 30 tablets | Teva Pharmaceuticals, Inc. |
| 00480-3276-56 | ELTROMBOPAG CHOLINE 54 mg/1 tablet, film coated | bottle of 30 tablets | Teva Pharmaceuticals, Inc. |
| 00480-3273-56 | ELTROMBOPAG CHOLINE 9 mg/1 tablet, film coated | bottle of 30 tablets | Teva Pharmaceuticals, Inc. |
Source: the FDA NDC Directory, current listings only. Only packages sold under Alvaiz’s own FDA approval (NDA 216774) are listed, never a generic. Some codes belong to companies that repackage Alvaiz: it is the same medicine in a different package.
What a Generic Alvaiz Means for You
Nothing Changes Until It Is in Pharmacies
Until a generic is actually for sale, keep filling Alvaiz as usual. When one arrives, there is nothing you need to sign up for.
Your Pharmacy May Switch You Automatically
Every state lets pharmacists fill a brand-name prescription with an FDA-approved generic rated as equivalent to it, and about 19 states require them to, unless your prescriber writes “dispense as written” or “brand medically necessary” on the prescription. Some states ask the pharmacist to tell you, or to get your OK first. A study of every state’s law has the details.
It Will Probably Look Different
US trademark law does not let a generic look exactly like the brand, so the color, shape or markings usually change. The active ingredient, strength and form are the same. An “authorized generic,” made by or for the brand’s own company, can look identical. The FDA explains.
Your Insurance May Change Too
Once a lower-cost version is available, many insurance plans charge more for the brand, or stop covering it. Your plan’s drug list (formulary) says how.
Until a generic is on US pharmacy shelves, be careful with websites that offer “generic Alvaiz”. The FDA warns that unlicensed online pharmacies sell counterfeit and unapproved medicines; its BeSafeRx page shows how to check a pharmacy.
Questions people ask about Alvaiz
Is there a generic for Alvaiz right now?
No. As of October 9, 2026 no generic eltrombopag choline is listed for sale in the FDA NDC Directory.
When will Alvaiz go generic?
October 2038 is the expected month, and that is probable but not certain. It is when Alvaiz’s patent 11,072,586 ends. That patent covers the active ingredient, the product’s formulation and a way of using it, and once it ends, generics should be able to go on sale as soon as the FDA approves them. The last listed patent runs to November 2038; a court ruling or a settlement can bring a generic sooner.
Will generic eltrombopag choline be the same as Alvaiz?
Yes in the ways that matter: the same active ingredient, strength and form, with proof that it reaches your blood the same way. Inactive ingredients can differ, which is why some people notice a different look or taste.
How much will the generic cost?
Nobody can say for sure before launch. No company is recorded as having applied to the FDA to make one yet, and a single company usually brings only a modest drop.
Has the FDA approved a generic Alvaiz?
Not yet. The FDA Orange Book lists no approved generic version of Alvaiz.
When does the Alvaiz patent expire?
One patent is listed for Alvaiz in the FDA Orange Book; it runs to November 2038. The one behind the expected month is patent 11,072,586, which ends in November 2038. A patent date is not the launch date: settlements and court rulings often bring a generic earlier, and FDA approval or a company’s own plans can make it later. The expected month on this page (October 2038) weighs all of that.
Changes to This Projection
- First generic expected October 2038 on this month’s schedule. A line is added here whenever a monthly update moves the month, the reason or how sure it is.
Every change to the expected month is logged here with the month we saw it.
Also Going Generic
- BunavailBuprenorphine Hydrochloride and Naloxone HydrochlorideJuly 2028
- Tobi PodhalerTobramycinNovember 2030
- Lonhala MagnairGlycopyrrolateDecember 2036
- YutrepiaTreprostinil SodiumMay 2037
- FrindovyxCyclophosphamideTBD no date yet
- PrestaliaAmlodipine Besylate and Perindopril ArginineTBD no date yet
About Alvaiz
- Generic name eltrombopag choline
- How it is taken By mouth
- Company Teva Pharmaceuticals Inc
- More drugs Brand-name drugs starting with A
- Have a question? A pharmacist answers, free. Ask about Alvaiz
Sources. The expected month: FDA Paragraph IV Patent Certifications list, federal court records, company announcements and securities filings (settlement dates, launch plans, sales). The record on this page: FDA Orange Book, Drugs@FDA (tentative approvals), FDA NDC Directory, CMS Medicare Part D Spending by Drug, Medicaid State Drug Utilization Data, FDA, Generic Competition and Drug Prices (2019). Updated October 9, 2026. Information, not medical advice.