Pentostatin Injection shortage
Pentostatin Injection is currently listed in shortage by the FDA. The FDA lists 1 affected product. The reported reason: Other. This page was last refreshed from FDA data on Sep 19, 2026.
Pentostatin injection (10 mg) is currently unavailable due to manufacturing delays at Pfizer, with supply not expected to return until mid-to-late 2027. No other manufacturers are listed as a source for this medicine right now.
Don’t stop or change your therapy on your own — ask your pharmacist about other manufacturers and your prescriber about a long-term plan.
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Pentostatin Injection. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
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Aug 27, 2026Currently in shortage1 of 1 product affected.
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Aug 27, 2026First reported to the FDA1 product first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: Hospira, Inc., a Pfizer Company 📞 844-646-4398 1 NDC click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Nipent, Injection, 10 mg, single dose vial (NDC 0409-0801-01) | — | Unavailable | Next delivery: Q2 2027; Estimated recovery: Q3 2027; Shortage per manufacturer: manufacturing delays | Other |
These rows are manufacturer reports to the FDA for Pentostatin Injection — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Pentostatin Injection? options further down this page.
Why is Pentostatin Injection in shortage?
Right now, the 10 mg single-dose vial of Pentostatin Injection made by Hospira (a Pfizer company) is unavailable due to manufacturing delays — basically, there's a hold-up at the factory that's preventing them from getting product out the door. The FDA reason code listed is "Other," which is a broad category, but Hospira has shared that the issue comes down to those manufacturing delays.
According to the information Hospira reported, the next delivery isn't expected until sometime in the second quarter of 2027, with supply expected to recover by the third quarter of 2027. So this is expected to be an extended shortage for this particular product from this manufacturer.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Pentostatin Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Pentostatin Injection?
Pentostatin injection is currently on the FDA drug-shortage list, and I want to walk you through what that means for you.
There is only one strength involved here, the 10 mg single-dose vial, and it is the strength that is affected. Right now that strength has no reported available source from the manufacturer on this record. The reason given is listed simply as "Other," with the maker also noting manufacturing delays. The manufacturer's timeline points to a next delivery in the second quarter of 2027 and an estimated recovery in the third quarter of 2027, so this may take some time to resolve.
Please keep in mind this report reflects only the manufacturer that filed it, and it may not match what your own pharmacy or treatment center actually has in stock.
Here is what I suggest:
- Do not stop, skip, or change your treatment on your own. Pentostatin is given as part of a care plan, so any change should come from your care team.
- Ask your pharmacy or infusion center to check with wholesalers and other suppliers for the 10 mg vial.
- Because the same medicine isn't listed from another maker in our records, talk with your prescriber about how to manage your treatment schedule if the vial cannot be found.
Manufacturer contact numbers are listed on this page for reference; pharmacies usually handle those calls.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.
Therapeutic equivalents & pricing 1 productclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| Nipent 2 mg/mL | Hospira, | 1 vial | — | AP | FDA listed |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Pentostatin Injection — that fall in the same broad treatment class (antineoplastic - antimetabolites) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Identity & classification
Where does this data come from?
Other oncology shortages
Pentostatin Injection shortage FAQs
Is Pentostatin Injection in shortage?
Why is Pentostatin Injection in shortage?
Which products are affected?
When will Pentostatin Injection be available again?
What should I do if I take Pentostatin Injection?
Still have a question about the Pentostatin Injection shortage?
Ask a pharmacist about this shortage →View Pentostatin Injection on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.