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Dextrose Monohydrate 5% Injection shortage

Dextrose Monohydrate 5% Injection is currently listed in shortage by the FDA. The FDA lists 36 affected products. The reported reason: Demand increase for the drug. This page was last refreshed from FDA data on Oct 2, 2026.

Current ⚠ Supply risk: Low Endocrinology/Metabolism, Gastroenterolo... 36 products 4 manufacturers 1,692 days · 4.6 yr First posted Feb 14, 2022 Updated Sep 22, 2026
Here’s the bottom line

Dextrose 5% injection (D5W) has been on the FDA shortage list for over a year due to high demand. All strengths still have available supply, and makers including Baxter, B. Braun, and Hospira have not reported a shortage.

Don’t stop or change your therapy on your own — ask your pharmacist about other manufacturers (see options) and your prescriber about a long-term plan.

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
36
Affected NDCs
4
Reporting manufacturers
4/4
Reporting mfrs supplying
4/4
Affected strengths supplied
0%
NDCs unavailable
1,692
Days in shortage
81,407
Medicaid Rx (2026)
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Oct 2, 2026 · yesterday

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Dextrose Monohydrate 5% Injection. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
36 NDCs
Available 36
Affected strengths still supplied
Among manufacturers reporting this shortage
4/4 strengths
Sourceable 4
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
4/4 makers
With supply 4
✓ Other manufacturers not reporting a shortage
Still-marketed Dextrose Monohydrate 5% Injection from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
B. Braun Medical Inc. Baxter Healthcare Corporation Baxter Healthcare Company Hospira, Inc. ICU Medical, Inc. Becton Dickinson and Company Fresenius Kabi USA, LLC
See all other options & details →
Shortage timeline
  1. Sep 22, 2026
    Currently in shortage
    36 of 36 products affected.
  2. Sep 17, 2026
    FDA refreshed this shortage record
    16 products updated.
  3. Sep 16, 2026
    FDA refreshed this shortage record
    10 products updated.
  4. Sep 15, 2026
    FDA refreshed this shortage record
    5 products updated.
  5. Jul 20, 2026
    More presentations reported
    1 more product added to the shortage.
  6. Feb 14, 2022
    First reported to the FDA
    35 products first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: B. Braun Medical Inc. 📞 800-227-2862 5 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Dextrose 5% In Plastic Container, Injection, 50 mg/1 mL (NDC 0264-1510-32) NDC 00264-1510-32 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 50 mg/1 mL (NDC 0264-1510-31) NDC 00264-1510-31 — Available — —
Current Dextrose Monohydrate 5%, Injection, 5 g/100 mL (NDC 0264-7510-20) NDC 00264-7510-20 — Available — —
Current Dextrose Monohydrate 5%, Injection, 5 g/100 mL (NDC 0264-7510-10) NDC 00264-7510-10 — Available — —
Current Dextrose Monohydrate 5%, Injection, 5 g/100 mL (NDC 0264-7510-00) NDC 00264-7510-00 — Available — —
Manufacturer: Baxter Healthcare 📞 888-229-0001 16 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Dextrose 5% In Plastic Container, Injection, 50 g/1000 mL (NDC 0338-0017-38) NDC 00338-0017-38 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0338-0551-18) NDC 00338-0551-18 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 50 g/1000 mL (NDC 0338-0017-03) NDC 00338-0017-03 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 50 g/1000 mL (NDC 0338-0017-02) NDC 00338-0017-02 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 2.5 g/50 mL (NDC 0338-9664-40) NDC 00338-9664-40 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 50 g/1000 mL (NDC 0338-0017-48) NDC 00338-0017-48 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0338-9666-35) NDC 00338-9666-35 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 50 g/1000 mL (NDC 0338-0017-31) NDC 00338-0017-31 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0338-0070-10) NDC 00338-0070-10 — Available — Demand increase for the drug
Current Dextrose 5% In Plastic Container, Injection, 50 g/1000 mL (NDC 0338-0017-10) NDC 00338-0017-10 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0338-0551-11) NDC 00338-0551-11 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 50 g/1000 mL (NDC 0338-0017-18) NDC 00338-0017-18 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 50 g/1000 mL (NDC 0338-0017-41) NDC 00338-0017-41 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 50 g/1000 mL (NDC 0338-0017-11) NDC 00338-0017-11 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0338-0074-30) NDC 00338-0074-30 — Available — —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0338-0078-20) NDC 00338-0078-20 — Available — —
Manufacturer: Fresenius Kabi USA, LLC 📞 888-386-1300 5 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Dextrose 5% In Plastic Container, Injection, 50 mg/1 mL (NDC 65219-456-60) NDC 65219-0456-60 — Available Check wholealers for inventory —
Current Dextrose 5% In Plastic Container, Injection, 50 mg/1 mL (NDC 65219-464-50) NDC 65219-0464-50 — Available Check wholesalers for inventory —
Current Dextrose 5% In Plastic Container, Injection, 50 mg/1 mL (NDC 65219-460-20) NDC 65219-0460-20 — Available Check wholesalers for inventory —
Current Dextrose 5% In Plastic Container, Injection, 50 mg/1 mL (NDC 65219-462-10) NDC 65219-0462-10 — Available Check wholesalers for inventory Demand increase for the drug
Current Dextrose 5% In Plastic Container, Injection, 50 mg/1 mL (NDC 65219-458-30) NDC 65219-0458-30 — Available Check wholesalers for inventory —
Manufacturer: Otsuka ICU Medical LLC 📞 1-866-829-9025 or [email protected] 10 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0990-7922-55) NDC 00990-7922-55 — Available This product is distributed by ICU Medical. For questions regarding this product, please contact ICU Medical. —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0990-7923-20) NDC 00990-7923-20 — Available This product is distributed by ICU Medical. For questions regarding this product, please contact ICU Medical. —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0990-7922-61) NDC 00990-7922-61 — Available This product is distributed by ICU Medical. For questions regarding this product, please contact ICU Medical. —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0990-7923-13) NDC 00990-7923-13 — Available This product is distributed by ICU Medical. For questions regarding this product, please contact ICU Medical. —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0990-7923-36) NDC 00990-7923-36 — Available This product is distributed by ICU Medical. For questions regarding this product, please contact ICU Medical. —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0990-7923-23) NDC 00990-7923-23 — Available This product is distributed by ICU Medical. For questions regarding this product, please contact ICU Medical. —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0990-7922-02) NDC 00990-7922-02 — Available This product is distributed by ICU Medical. For questions regarding this product, please contact ICU Medical. —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0990-7922-09) NDC 00990-7922-09 — Available This product is distributed by ICU Medical. For questions regarding this product, please contact ICU Medical. —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0990-7923-37) NDC 00990-7923-37 — Available This product is distributed by ICU Medical. For questions regarding this product, please contact ICU Medical. —
Current Dextrose 5% In Plastic Container, Injection, 5 g/100 mL (NDC 0990-7922-03) NDC 00990-7922-03 — Available This product is distributed by ICU Medical. For questions regarding this product, please contact ICU Medical. —

These rows are manufacturer reports to the FDA for Dextrose Monohydrate 5% Injection — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Dextrose Monohydrate 5% Injection? options further down this page.

Why is Dextrose Monohydrate 5% Injection in shortage?

Dextrose 5% injection (also called "D5W") is on the FDA shortage list mainly because more people need it than usual — demand has gone up beyond what suppliers can easily keep up with. The specific reason reported to the FDA is a demand increase. Fresenius Kabi, Baxter Healthcare, B. Braun Medical, and Otsuka/ICU Medical have all reported their products to the FDA, and at this time all listed package sizes — including 100 mL and 1,000 mL bags — are marked as available from these manufacturers.

Even though the products are listed as currently available, Fresenius Kabi noted that inventory can vary, so stock levels may not be consistent everywhere. The shortage listing is essentially a heads-up that demand has been outpacing the usual supply, which can cause spotty availability at certain locations even when the product technically exists in the system.

FDA reason code(s): Demand increase for the drug

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Dextrose Monohydrate 5% Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Dextrose Monohydrate 5% Injection?

Dextrose Monohydrate 5% Injection is currently on the FDA shortage list, but the supply picture here is reassuring. All four strengths on this record still have an available source, and every one of the four manufacturers listed is reporting supply.

To be specific, each strength — 50 mg/1 mL, 5 g/100 mL, 50 g/1000 mL, and 2.5 g/50 mL — currently has an available source. None of these strengths is listed as having no source right now. The reason the FDA gives is simply an increase in demand for this product, not a manufacturing failure. Because this is a widely used injectable solution, it was placed on the list even though supply is still flowing, which is why the overall risk is rated low.

Here is what I suggest:

  • Do not stop, skip, or change how you use this medicine on your own.
  • Ask your pharmacy or facility to order your strength; they can check wholesalers and multiple manufacturers, several of whom report stock.
  • The same medicine is available from other makers (such as Baxter, B. Braun, Fresenius Kabi, and ICU Medical) — your pharmacy may be able to source one of these, though it may not be in local stock.
  • If your exact product cannot be found, ask your prescriber or pharmacist about suitable options.

Manufacturer contact numbers are listed on this page for reference; pharmacies usually make these calls. This information comes from national, manufacturer-reported FDA data and may not match your local pharmacy's actual stock.

See “Where else can I get Dextrose Monohydrate 5% Injection?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Dextrose guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Dextrose guide →

Where else can I get Dextrose Monohydrate 5% Injection?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Dextrose Monohydrate 5% Injection is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Same medicine, other manufacturers (not reported short)

Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:

ProductStrengthForm / routeManufacturerNDC
Dextrose DEXTROSE MONOHYDRATE 50 mg/mL Injection, Solution · Intravenous B. Braun Medical Inc. 00264-1510-36
Dextrose DEXTROSE MONOHYDRATE 50 g/1000mL Injection, Solution · Intravenous Baxter Healthcare Corporation 00338-0017-01
Dextrose DEXTROSE MONOHYDRATE 5 g/100mL Injection, Solution · Intravenous Baxter Healthcare Corporation 00338-0062-30
Dextrose DEXTROSE MONOHYDRATE 2.5 g/50mL Injection · Intravenous Baxter Healthcare Company 00338-9143-30
Dextrose DEXTROSE MONOHYDRATE 5 g/100mL Injection · Intravenous Baxter Healthcare Company 00338-9147-30
Dextrose DEXTROSE MONOHYDRATE 2.5 g/50mL Injection, Solution · Intravenous Baxter Healthcare Corporation 00338-9649-75
Dextrose DEXTROSE MONOHYDRATE 50 mg/mL Injection, Solution · Intravenous Hospira, Inc. 00409-7100-02
Dextrose DEXTROSE MONOHYDRATE 5 g/100mL Injection, Solution · Intravenous ICU Medical, Inc. 00990-7922-53
Dextrose DEXTROSE MONOHYDRATE 50 mg/mL Injection, Solution · Intravenous Becton Dickinson and Company 17271-0720-02
Dextrose DEXTROSE MONOHYDRATE 50 mg/mL Injection, Solution · Intravenous Fresenius Kabi USA, LLC 63323-0624-10
Dextrose DEXTROSE MONOHYDRATE 2500 mg/50mL Injection, Solution · Intravenous Fresenius Kabi USA, LLC 65219-0234-10
Dextrose DEXTROSE MONOHYDRATE 5000 mg/100mL Injection, Solution · Intravenous Fresenius Kabi USA, LLC 65219-0236-10
Therapeutic equivalents & pricing 3 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Dextrose 50 mg/mLNDC 00264-1510-32 B. 100 ml — AP FDA listed
Dextrose 50 mg/mLNDC 00264-1510-31 B. 50 ml — AP FDA listed
Dextrose 5 g/100mLNDC 00264-7510-20 B. 250 ml — AP FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Dextrose Monohydrate 5% Injection — that fall in the same broad treatment class (iv solutions: dextrose-water) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 001972
GCN 06641
HICL code 000915
Ingredient (HICL) Dextrose 5 % In Water
HIC1 code C
Therapeutic class — broad (HIC1) Electrolyte Balance/Metabolism/Nutrition
HIC2 code C5
Therapeutic class — intermediate (HIC2) Carbohydrates And/Or Proteins
HIC3 code C5J
Therapeutic class — specific (HIC3) Iv Solutions: Dextrose-Water
AHFS code 40:20.00.00
AHFS class Caloric Agents
FDB label name DEXTROSE 5%-WATER IV SOLN
FDB brand name Dextrose In Water
Legend status F — Federal legend — prescription drug or device
GPI-1480100020002015
GPI classDextrose
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other endocrinology/metabolism, gastroenterology, other, pediatric shortages

Dextrose Monohydrate 5% Injection shortage FAQs

Is Dextrose Monohydrate 5% Injection in shortage?
Yes — the FDA currently lists Dextrose Monohydrate 5% Injection in shortage (status: “Current”, first reported Feb 14, 2022). 36 of 36 products are affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Why is Dextrose Monohydrate 5% Injection in shortage?
The manufacturer-reported reason on file with the FDA: Demand increase for the drug.
Which products are affected?
Dextrose 5% In Plastic Container, Injection, 50 mg/1 mL (NDC 0264-1510-32) (NDC 00264-1510-32); Dextrose 5% In Plastic Container, Injection, 50 mg/1 mL (NDC 0264-1510-31) (NDC 00264-1510-31); Dextrose Monohydrate 5%, Injection, 5 g/100 mL (NDC 0264-7510-20) (NDC 00264-7510-20). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Dextrose Monohydrate 5% Injection be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Dextrose Monohydrate 5% somewhere?
Other manufacturers (B. Braun Medical Inc., Baxter Healthcare Corporation, Baxter Healthcare Company and others) still market it and have not reported a shortage. See “Where else can I get Dextrose Monohydrate 5% Injection?” above — stock still varies by pharmacy.
What should I do if I take Dextrose Monohydrate 5% Injection?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Dextrose Monohydrate 5% Injection shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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