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Metronidazole Injection shortage

Metronidazole Injection is currently listed in shortage by the FDA. The FDA lists 4 affected products. The reported reason: Other; Discontinuation of the manufacture of the drug. This page was last refreshed from FDA data on Sep 22, 2026.

Current ⚠ Supply risk: Low Anti-Infective 4 products 3 manufacturers 1,713 days · 4.7 yr First posted Jan 13, 2022 Updated Sep 17, 2026
Here’s the bottom line

Gland Pharma is permanently stopping its metronidazole injection, creating a shortage that has lasted over a year. The 500 mg/100 mL strength is still listed by other manufacturers not reporting a shortage, including Baxter Healthcare, Civica, WG Critical Care, and Amneal Pharmaceuticals.

Don’t stop or change your therapy on your own — ask your pharmacist about other manufacturers (see options) and your prescriber about a long-term plan.

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
4
Affected NDCs
3
Reporting manufacturers
2/3
Reporting mfrs supplying
1/1
Affected strengths supplied
25%
NDCs unavailable
1,713
Days in shortage
22,486
Medicaid Rx (2026)
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Sep 22, 2026 · today

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Metronidazole Injection. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
4 NDCs
Available 1 Limited 2 Unavailable 1
Affected strengths still supplied
Among manufacturers reporting this shortage
1/1 strengths
Sourceable 1
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
2/3 makers
With supply 2 No supply 1
✓ Other manufacturers not reporting a shortage
Still-marketed Metronidazole Injection from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
Baxter Healthcare Corporation WG Critical Care, LLC Civica, Inc. Amneal Pharmaceuticals Private Limited
Plus 1 alternative dosage form of Metronidazole.
See all other options & details →
Shortage timeline
  1. Sep 17, 2026
    Currently in shortage
    4 of 4 products affected.
  2. Aug 18, 2026
    FDA refreshed this shortage record
    2 products updated.
  3. Jul 22, 2026
    FDA refreshed this shortage record
    1 product updated.
  4. Jan 13, 2022
    First reported to the FDA
    4 products first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Baxter Healthcare 📞 888-229-0001 1 NDC click to expand
Status NDC / product Strength Availability Related information Reason
Current Flagyl I.v. Rtu In Plastic Container, Injection, 500 mg/100 mL (NDC 0338-1055-48) NDC 00338-1055-48 Available
Manufacturer: Gland Pharma Limited 📞 Distributed by Sun Pharma 1 NDC click to expand
Status NDC / product Strength Availability Related information Reason
Current Metronidazole In Plastic Container, Injection, 500 mg/100 mL (NDC 47335-993-01) NDC 47335-0993-01 Unavailable Discontinuation of the manufacture of the drug Discontinuation of the manufacture of the drug
Manufacturer: InfoRLife SA 📞 Sagent: 866-625-1618 2 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Metronidazole, Injection, 500 mg/100 mL (NDC 25021-131-82) NDC 25021-0131-82 Limited Availability Estimated recovery: August 2026; Marketed by Sagent Pharmaceuticals Other
Current Metronidazole in Flexible Container, Injection, 500 mg/100 mL (NDC 0409-0152-24) NDC 00409-0152-24 Limited Availability Labeler: Hospira Inc. Other

These rows are manufacturer reports to the FDA for Metronidazole Injection — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Metronidazole Injection? options further down this page.

Why is Metronidazole Injection in shortage?

Metronidazole injection (500 mg/100 mL) is on the shortage list for a couple of different reasons depending on the manufacturer. Gland Pharma Limited has permanently stopped making their version of this product altogether — that's the "discontinuation" you may see mentioned. On top of that, two other suppliers — Hospira and Sagent Pharmaceuticals — currently have only limited amounts available, with Sagent's supply expected to recover around August 2026. The reason given for those two is listed as "other," meaning the specific cause wasn't publicly shared.

It's worth knowing that this shortage report reflects only the manufacturers who filed it. Baxter Healthcare's version — Flagyl I.V. RTU in a plastic container, also 500 mg/100 mL — is reported as available through this same filing, so not every supplier of this product is in the same situation.

FDA reason code(s): Other; Discontinuation of the manufacture of the drug

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Metronidazole Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Metronidazole Injection?

Metronidazole injection is currently on the FDA shortage list. This is a medicine given through a vein, usually in a hospital or clinic setting.

There is only one strength involved, 500 mg/100 mL, and that strength still has an available source. Two of the three manufacturers on this record continue to report supply, so no strength is completely without a source right now.

The reported reasons include one manufacturer (Hospira/Sagent) discontinuing its version, with an estimated recovery noted for August 2026, and a separate discontinuation from another maker. Because this affects only certain suppliers—not every company that makes this medicine—other manufacturers may still be able to fill the gap. Overall supply risk is rated low.

Here is what you can do:

  • Do not stop, skip, or change your treatment on your own.
  • Ask your pharmacy or care team to order the 500 mg/100 mL strength, since a source is still available; they can check wholesalers and other manufacturers.
  • The same medicine may be available from other makers such as Baxter, WG Critical Care, Civica, or Amneal—your pharmacy may be able to source one, though it may not be in local stock.

Manufacturer contact numbers are listed on this page for reference. This reflects national data and may not match your local supply.

See “Where else can I get Metronidazole Injection?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Metronidazole guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Metronidazole guide →

Where else can I get Metronidazole Injection?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Metronidazole Injection is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Same medicine, other manufacturers (not reported short)

Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:

ProductStrengthForm / routeManufacturerNDC
Metronidazole METRONIDAZOLE 500 mg/100mL Injection, Solution · Intravenous Baxter Healthcare Corporation 00338-9541-24
Metronidazole METRONIDAZOLE 500 mg/100mL Injection, Solution · Intravenous WG Critical Care, LLC 44567-0750-24
Metronidazole METRONIDAZOLE 500 mg/100mL Injection, Solution · Intravenous Civica, Inc. 72572-0540-24
Metronidazole METRONIDAZOLE 500 mg/100mL Injection, Solution · Intravenous Amneal Pharmaceuticals Private Limited 80830-2465-09

Alternative dosage forms of Metronidazole

A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:

Therapeutic equivalents & pricing 11 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Metronidazole 500 mg/100mLNDC 00264-5535-32 B. 100 ml FDA listed
Metronidazole 500 mg/100mLNDC 00338-1055-48 Baxter 100 ml AP FDA listed
Metronidazole 500 mg/100mLNDC 00338-9541-24 Baxter 100 ml AP FDA listed
Metronidazole 500 mg/100mLNDC 00404-9991-00 Henry 100 ml AP FDA listed
Metronidazole 5 mg/mLNDC 00409-0152-24 Hospira, 24 pouches AP FDA listed
Metronidazole 500 mg/100mLNDC 25021-0131-82 Sagent 24 pouches AP FDA listed
Metronidazole 500 mg/100mLNDC 44567-0750-24 WG 24 pouches AP FDA listed
Metronidazole 500 mg/100mLNDC 47335-0993-01 Sun 1 pouch AP FDA listed
Metronidazole 500 mg/100mLNDC 68083-0373-04 Gland 4 pouches AP FDA listed
Metronidazole 500 mg/100mLNDC 72572-0540-24 Civica, 100 ml AP FDA listed
Metronidazole 500 mg/100mLNDC 80830-2465-09 Amneal 24 pouches AP FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Metronidazole Injection — that fall in the same broad treatment class (anaerobic antiprotozoal-antibacterial agents) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 009588
GCN 43025
HICL code 008259
Ingredient (HICL) Metronidazole/Sodium Chloride
HIC1 code W
Therapeutic class — broad (HIC1) Anti-Infecting Agents
HIC2 code W4
Therapeutic class — intermediate (HIC2) Antiparasitics
HIC3 code W4E
Therapeutic class — specific (HIC3) Anaerobic Antiprotozoal-Antibacterial Agents
AHFS code 08:30.04.00
AHFS class Amebicides
FDB label name METRONIDAZOLE 500 MG/100 ML
FDB brand name Metronidazole
Legend status F — Federal legend — prescription drug or device
GPI-1416000035002030
GPI classmetroNIDAZOLE
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other anti-infective shortages

Metronidazole Injection shortage FAQs

Is Metronidazole Injection in shortage?
Yes — the FDA currently lists Metronidazole Injection in shortage (status: “Current”, first reported Jan 13, 2022). 4 of 4 products are affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Why is Metronidazole Injection in shortage?
The manufacturer-reported reason on file with the FDA: Other; Discontinuation of the manufacture of the drug.
Which products are affected?
Flagyl I.v. Rtu In Plastic Container, Injection, 500 mg/100 mL (NDC 0338-1055-48) (NDC 00338-1055-48); Metronidazole In Plastic Container, Injection, 500 mg/100 mL (NDC 47335-993-01) (NDC 47335-0993-01); Metronidazole, Injection, 500 mg/100 mL (NDC 25021-131-82) (NDC 25021-0131-82). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Metronidazole Injection be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Metronidazole somewhere?
Other manufacturers (Baxter Healthcare Corporation, WG Critical Care, LLC, Civica, Inc. and others) still market it and have not reported a shortage. 1 alternative dosage form of Metronidazole is also listed. See “Where else can I get Metronidazole Injection?” above — stock still varies by pharmacy.
What should I do if I take Metronidazole Injection?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Metronidazole Injection shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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