Hydromorphone Hydrochloride Suppository shortage
Hydromorphone Hydrochloride Suppository is currently listed in shortage by the FDA. The FDA lists 1 affected product. This page was last refreshed from FDA data on Oct 3, 2026.
Padagis is permanently stopping production of hydromorphone suppositories (3 mg), and none remain available from them. Bryant Ranch Prepack still lists the same 3 mg suppository, so supply may exist from that source.
Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Hydromorphone Hydrochloride Suppository. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
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Jul 23, 2026Currently in shortage1 of 1 product affected.
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Jul 23, 2026First reported to the FDA1 product first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: Padagis US LLC 📞 (800) 775-2054 1 NDC click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| To Be Discontinued | Hydromorphone Hydrochloride, Suppository, 3 mg (NDC 0574-7224-06) | — | — | Discontinuation of the manufacture of the drug | — |
These rows are manufacturer reports to the FDA for Hydromorphone Hydrochloride Suppository — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Hydromorphone Hydrochloride Suppository? options further down this page.
Why is Hydromorphone Hydrochloride Suppository in shortage?
Padagis US LLC has reported to the FDA that they are permanently stopping the manufacturing of their 3 mg hydromorphone hydrochloride suppositories. This isn't a temporary shortage or a factory hold-up — it's a full discontinuation of this specific product by this manufacturer.
It's worth noting that Padagis did not share a specific public reason for why they made this decision — the FDA data simply notes that manufacturing of this product is being discontinued. This report reflects only what Padagis has filed, so it speaks only to their 3 mg suppository product.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Hydromorphone Hydrochloride Suppository, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Hydromorphone Hydrochloride Suppository?
Hydromorphone hydrochloride 3 mg suppositories are currently listed on the FDA drug-shortage report. I want to walk you through what this means so you can plan your next steps calmly.
Right now, the one strength on this record — the 3 mg suppository — has no available source reported. The reason given is that the manufacturer, Padagis US LLC, is discontinuing production of this product. Because this is listed as a discontinuation rather than a temporary delay, the supply problem for this maker may be permanent. That makes a conversation with your prescriber the right next step, rather than something to leave until your supply runs low.
Please keep this in mind, in order:
- Do not stop, skip, or change your doses on your own — keep taking your medicine as prescribed while you sort this out.
- Ask your pharmacy to check whether they can source the same medicine from another maker; our records show a 3 mg hydromorphone suppository from Bryant Ranch Prepack, though it may not be in your local stock.
- If your exact product cannot be found, ask your prescriber or pharmacist about a clinician-chosen alternative that fits your needs.
Manufacturer contact numbers are listed on this page for reference; your pharmacy usually handles those calls.
This is general, national information and may not match your local pharmacy's actual stock.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
- This is a controlled substance. Transfers between pharmacies and switching strengths have extra federal/state rules — ask the pharmacy before you assume a transfer is possible.
Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.
Where else can I get Hydromorphone Hydrochloride Suppository?
FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Hydromorphone Hydrochloride Suppository is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.
Same medicine, other manufacturers (not reported short)
Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:
| Product | Strength | Form / route | Manufacturer | NDC |
|---|---|---|---|---|
| Hydromorphone Hydrochloride | HYDROMORPHONE HYDROCHLORIDE 3 mg/1 | Suppository · Rectal | Bryant Ranch Prepack | 63629-2532-01 |
Alternative dosage forms of Hydromorphone Hydrochloride
A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:
Therapeutic equivalents & pricing 2 productsclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| Hydromorphone Hydrochloride 3 mg | Padagis | 6 suppositories | — | — | FDA listed |
| Hydromorphone Hydrochloride 3 mg | Bryant | 6 suppositories | — | — | FDA listed |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Hydromorphone Hydrochloride Suppository — that fall in the same broad treatment class (opioid analgesics) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Identity & classification
Where does this data come from?
Other analgesia/addiction shortages
Hydromorphone Hydrochloride Suppository shortage FAQs
Is Hydromorphone Hydrochloride Suppository in shortage?
Which products are affected?
When will Hydromorphone Hydrochloride Suppository be available again?
Can I still get Hydromorphone Hydrochloride somewhere?
What should I do if I take Hydromorphone Hydrochloride Suppository?
Still have a question about the Hydromorphone Hydrochloride Suppository shortage?
Ask a pharmacist about this shortage →View Hydromorphone Hydrochloride Suppository on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.