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Nitroglycerin Ointment shortage

Nitroglycerin Ointment is currently listed in shortage by the FDA. The FDA lists 1 affected product. This page was last refreshed from FDA data on Oct 2, 2026.

To Be Discontinued ⚠ Supply risk: High Analgesia/Addiction 1 product 172 days First posted Apr 14, 2026 Updated Apr 14, 2026
Here’s the bottom line

AbbVie is permanently stopping production of its nitroglycerin 0.4% ointment. Other makers — including Cosette Pharmaceuticals, Encube Ethicals, Trupharma, and Bryant Ranch Prepack — still list nitroglycerin ointment as available.

Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
1
Affected NDCs
1
Reporting manufacturers
0/1
Reporting mfrs supplying
0/1
Affected strengths supplied
172
Days in shortage
449
Medicaid Rx (2025)
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Oct 2, 2026 · yesterday

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Nitroglycerin Ointment. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
1 NDCs
To be discontinued 1
Affected strengths still supplied
Among manufacturers reporting this shortage
0/1 strengths
No supply 1
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
0/1 makers
No supply 1
✓ Other manufacturers not reporting a shortage
Still-marketed Nitroglycerin Ointment from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
Cosette Pharmaceuticals, Inc. Encube Ethicals, Inc. Trupharma, LLC Bryant Ranch Prepack Solaris Pharma Corporation
Plus 19 alternative dosage forms of Nitroglycerin.
See all other options & details →
Shortage timeline
  1. Apr 14, 2026
    Currently in shortage
    1 of 1 product affected.
  2. Apr 14, 2026
    First reported to the FDA
    1 product first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: AbbVie Inc. 📞 800-678-1605 1 NDC click to expand
Status NDC / product Strength Availability Related information Reason
To Be Discontinued Rectiv, Ointment, 0.4% (NDC 58914-301-80) NDC 58914-0301-80 — — Discontinuation of the manufacture of the drug —

These rows are manufacturer reports to the FDA for Nitroglycerin Ointment — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Nitroglycerin Ointment? options further down this page.

Why is Nitroglycerin Ointment in shortage?

AbbVie has reported to the FDA that they are permanently stopping the manufacture of their 0.4% nitroglycerin ointment, Rectiv (the 80-unit package). That's the only detail they shared — they didn't provide a specific public reason for why they made this decision.

It's worth knowing that this report only covers AbbVie's Rectiv product. It doesn't mean nitroglycerin ointment is disappearing entirely — other manufacturers may still produce their own versions, and those are listed separately on this page.

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Nitroglycerin Ointment, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Nitroglycerin Ointment?

Nitroglycerin ointment (0.4%) is currently listed on the FDA drug-shortage list. I want to walk you through what this means so you can plan calmly.

The strength involved here is the 0.4% ointment, and right now there is no available source reported for it. The manufacturer on this record, AbbVie (the brand Rectiv), has reported that this product is being discontinued — meaning they are stopping its manufacture. Because this is a discontinuation, this particular supply problem may be permanent rather than temporary. That makes a conversation with your prescriber the right next step.

At the same time, this report reflects only that one manufacturer. The same medicine — nitroglycerin 4 mg/g ointment — is still made by other companies, so it may still be possible to obtain.

Here is what I suggest, in order:

  • Do not stop, skip, or change how you use this medicine on your own.
  • Ask your pharmacy to check whether the same nitroglycerin ointment is available from another maker, such as Cosette, Encube, Trupharma, Bryant Ranch, or Solaris — though it may not be in local stock right away.
  • If it cannot be found, ask your prescriber or pharmacist about a clinician-chosen option.

Manufacturer contact numbers are listed on this page for reference; pharmacies usually handle those calls. This is general, national information and may not match your local pharmacy's actual stock.

See “Where else can I get Nitroglycerin Ointment?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Nitroglycerin Topical guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Nitroglycerin Topical guide →

Where else can I get Nitroglycerin Ointment?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Nitroglycerin Ointment is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Same medicine, other manufacturers (not reported short)

Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:

ProductStrengthForm / routeManufacturerNDC
Nitroglycerin NITROGLYCERIN 4 mg/g Ointment · Rectal Cosette Pharmaceuticals, Inc. 00713-0564-31
Nitroglycerin NITROGLYCERIN 4 mg/g Ointment · Rectal Encube Ethicals, Inc. 21922-0048-05
Nitroglycerin NITROGLYCERIN 4 mg/g Ointment · Rectal Trupharma, LLC 52817-0835-30
Nitroglycerin NITROGLYCERIN 4 mg/g Ointment · Rectal Bryant Ranch Prepack 72162-2643-03
Nitroglycerin NITROGLYCERIN 4 mg/g Ointment · Rectal Solaris Pharma Corporation 73473-0500-30

Alternative dosage forms of Nitroglycerin

A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:

Therapeutic equivalents & pricing 7 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Nitroglycerin 4 mg/gNDC 00713-0564-31 Cosette 1 tube $8.315 save 60% AB Availability likely
Nitroglycerin 4 mg/gNDC 21922-0048-05 Encube 1 tube $8.315 save 60% AB Availability likely
Nitroglycerin 4 mg/gNDC 52817-0835-30 Trupharma, 1 tube $8.315 save 60% AB Availability likely
Nitroglycerin 4 mg/gNDC 73473-0500-30 Solaris 30 g $8.315 save 60% AB Availability likely
Nitroglycerin 4 mg/gNDC 45802-0932-94 Padagis 1 tube $8.315 save 60% AB Availability likely
Rectiv 4 mg/gNDC 58914-0301-80 Allergan, 1 tube $20.586 — Availability likely
Nitroglycerin 4 mg/gNDC 72162-2643-03 Bryant 30 g — AB FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Identity & classification

GCN Seq No 059201
GCN 24745
HICL code 000159
Ingredient (HICL) Nitroglycerin
HIC1 code Q
Therapeutic class — broad (HIC1) Ear/Eye/Nose/Rectum/Topical/Vagina/Other
HIC2 code Q3
Therapeutic class — intermediate (HIC2) Anal-Rectal Preparations
HIC3 code Q3T
Therapeutic class — specific (HIC3) Local Anorectal Nitrate Preparations
AHFS code 24:08.08.00
AHFS class Nitrates And Nitrites
FDB label name RECTIV 0.4% OINTMENT
FDB brand name Rectiv
Legend status F — Federal legend — prescription drug or device
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other analgesia/addiction shortages

Nitroglycerin Ointment shortage FAQs

Is Nitroglycerin Ointment in shortage?
Yes — the FDA currently lists Nitroglycerin Ointment in shortage (status: “To Be Discontinued”, first reported Apr 14, 2026). 1 of 1 product is affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Which products are affected?
Rectiv, Ointment, 0.4% (NDC 58914-301-80) (NDC 58914-0301-80). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Nitroglycerin Ointment be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Nitroglycerin somewhere?
Other manufacturers (Cosette Pharmaceuticals, Inc., Encube Ethicals, Inc., Trupharma, LLC and others) still market it and have not reported a shortage. 19 alternative dosage forms of Nitroglycerin are also listed. See “Where else can I get Nitroglycerin Ointment?” above — stock still varies by pharmacy.
What should I do if I take Nitroglycerin Ointment?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Nitroglycerin Ointment shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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