Morphine Sulfate Suppository shortage
Morphine Sulfate Suppository is currently listed in shortage by the FDA. The FDA lists 4 affected products. This page was last refreshed from FDA data on Oct 1, 2026.
Padagis is permanently stopping production of morphine sulfate suppositories, including the 5 mg, 10 mg, 20 mg, and 30 mg strengths. No other manufacturers of this product are currently listed as having supply available.
Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Morphine Sulfate Suppository. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
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Jul 23, 2026Currently in shortage4 of 4 products affected.
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Jul 23, 2026First reported to the FDA4 products first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: Padagis US LLC 📞 (800) 775-2054 4 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| To Be Discontinued | Morphine Sulfate, Suppository, 10 mg (NDC 0574-7112-12) | — | — | Discontinuation of the manufacture of the drug | — |
| To Be Discontinued | Morphine Sulfate, Suppository, 5 mg (NDC 0574-7110-12) | — | — | Discontinuation of the manufacture of the drug | — |
| To Be Discontinued | Morphine Sulfate, Suppository, 30 mg (NDC 0574-7116-12) | — | — | Discontinuation of the manufacture of the drug | — |
| To Be Discontinued | Morphine Sulfate, Suppository, 20 mg (NDC 0574-7114-12) | — | — | Discontinuation of the manufacture of the drug | — |
These rows are manufacturer reports to the FDA for Morphine Sulfate Suppository — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Morphine Sulfate Suppository? options further down this page.
Why is Morphine Sulfate Suppository in shortage?
Padagis US LLC has reported to the FDA that they are permanently stopping the manufacturing of their morphine sulfate suppositories — this affects all four strengths they made: the 5 mg, 10 mg, 20 mg, and 30 mg suppositories. This isn't a temporary shortage or a factory delay — it's a permanent decision by Padagis to stop making these products altogether.
It's worth knowing that Padagis did not share a specific public reason why they made this decision — just that the manufacturing is being discontinued. This report reflects only what Padagis has filed with the FDA, so it speaks only to their products and not to what other manufacturers may be doing.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Morphine Sulfate Suppository, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Morphine Sulfate Suppository?
Morphine Sulfate Suppository is currently on the FDA drug-shortage list, and I want to walk you through what that means for you.
All four strengths reported to the FDA — the 5 mg, 10 mg, 20 mg, and 30 mg — have no available source at this time. In this record, the manufacturer (Padagis US LLC) has listed each strength as being discontinued. Because this is marked "to be discontinued," this supply problem may be permanent rather than a short pause, so planning ahead with your care team is the right next step.
I know this is not easy to read, especially if this medicine is part of your pain care. Please do not stop or change your dose on your own — that can cause real harm.
Here is what I suggest:
- Reach out to your prescriber or pharmacist soon to talk about options, since this product is being discontinued and there are no other makers listed here.
- Ask whether a clinician-chosen alternative or a different approach to your dose would be appropriate for you.
- The manufacturer's contact number is listed on this page for reference, though your pharmacy usually handles those calls.
This information comes from national, manufacturer-reported FDA data and may not match your local pharmacy's stock. Your care team can guide the best path forward for you.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
- This is a controlled substance. Transfers between pharmacies and switching strengths have extra federal/state rules — ask the pharmacy before you assume a transfer is possible.
Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.
Where else can I get Morphine Sulfate Suppository?
FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Morphine Sulfate Suppository is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.
Alternative dosage forms of Morphine Sulfate
A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:
Therapeutic equivalents & pricing 6 productsclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| Morphine Sulfate 10 mg | Padagis | 12 suppositories | — | — | FDA listed |
| Morphine Sulfate 10 mg | Bryant | 12 suppositories | — | — | FDA listed |
| Morphine Sulfate 5 mg | Padagis | 12 suppositories | — | — | FDA listed |
| Morphine Sulfate 5 mg | Bryant | 12 suppositories | — | — | FDA listed |
| Morphine Sulfate 30 mg | Padagis | 12 suppositories | — | — | FDA listed |
| Morphine Sulfate 30 mg | Bryant | 12 suppositories | — | — | FDA listed |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Morphine Sulfate Suppository — that fall in the same broad treatment class (opioid analgesics) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Identity & classification
Where does this data come from?
Other analgesia/addiction shortages
Morphine Sulfate Suppository shortage FAQs
Is Morphine Sulfate Suppository in shortage?
Which products are affected?
When will Morphine Sulfate Suppository be available again?
Can I still get Morphine Sulfate somewhere?
What should I do if I take Morphine Sulfate Suppository?
Still have a question about the Morphine Sulfate Suppository shortage?
Ask a pharmacist about this shortage →View Morphine Sulfate Suppository on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.