Rifampin Capsule shortage
Yes — Rifampin capsules are on the FDA drug shortage list as of Oct 5, 2026. 9 products from 2 companies are affected; the reported reason is discontinuation of the manufacture of the drug. 5 other companies list the same medicine with the FDA and have not reported a shortage.
Epic Pharma is stopping production of rifampin capsules, and that change may be permanent. Other makers — including Major Pharmaceuticals and American Health Packaging — still list both the 150 mg and 300 mg capsules as available.
Don’t stop or change your therapy on your own — ask your pharmacist about other companies’ versions (see options) and your prescriber about a long-term plan.
Do you take this medicine? See the ‘What to do’ note from Dr. Brian Staiger, PharmD →Is rifampin still in shortage? — status as of Oct 5, 2026
Yes. As of Oct 5, 2026, the FDA lists rifampin capsules as a current shortage; 2 of 2 affected strengths still have a listed source, 2 of 2 reporting companies report supply, and 5 other companies list it without a shortage report.
The charts count only the companies that reported this shortage to the FDA; companies that haven’t reported a problem are in the green card, and the Supply-Risk rating counts them too.
Shortage timeline
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Sep 15, 2026Currently in shortage9 of 9 products affected.
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Sep 1, 2026FDA refreshed this shortage record3 products updated.
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Dec 22, 2021First reported to the FDA9 products first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
Which rifampin products are affected — by company
Company: Epic Pharma, LLC 📞 (718) 276-8600 ext. 3 6 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Rifampin Capsule, 150 mg | 150 mg | Available | — | — |
| Current | Rifampin Capsule, 300 mg | 300 mg | Unavailable | Discontinuation of the manufacture of the drug | Discontinuation of the manufacture of the drug |
| Current | Rifampin Capsule, 300 mg | 300 mg | Unavailable | Discontinuation of the manufacture of the drug | Discontinuation of the manufacture of the drug |
| Current | Rifampin Capsule, 150 mg | 150 mg | Unavailable | Discontinuation of the manufacture of the drug | Discontinuation of the manufacture of the drug |
| Current | Rifampin Capsule, 300 mg | 300 mg | Unavailable | Discontinuation of the manufacture of the drug | Discontinuation of the manufacture of the drug |
| Current | Rifampin Capsule, 300 mg | 300 mg | Available | — | — |
Company: Lupin Pharmaceuticals, Inc. 📞 866-587-4617 3 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Rifampin Capsule, 300 mg | 300 mg | Available | — | — |
| Current | Rifampin Capsule, 300 mg | 300 mg | Available | — | — |
| Current | Rifampin Capsule, 150 mg | 150 mg | Available | — | — |
These rows are company reports to the FDA for Rifampin Capsule — they do not cover every company that lists this medicine. A company appears here only if it told the FDA it has a supply problem, so other companies may still have stock. That’s the basis for the Where else can I get rifampin? options further down this page.
Why is rifampin in shortage?
Rifampin capsules made by Epic Pharma are on the shortage list because the company has permanently stopped making several of their specific package sizes. For the 300 mg capsules, Epic Pharma has discontinued most of their package sizes, though their 60-count bottle (NDC 42806-799-60) is still available. For the 150 mg capsules, their 1-count package has been discontinued, but their 30-count bottle (NDC 42806-801-30) is still available from them. Epic Pharma did not share any additional public explanation beyond the decision to stop manufacturing those specific presentations.
It's worth knowing that Lupin Pharmaceuticals reported to the FDA separately, and their rifampin capsules in both the 150 mg and 300 mg strengths show as available — so this report reflects only what's happening with Epic Pharma's specific discontinued packages.
Based on the company-reported reason(s) and notes on file with the FDA for Rifampin Capsule, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as companies report changes.
What should I do if I take rifampin?
Rifampin capsules are currently listed on the FDA drug-shortage list, but both strengths you may be taking still have an available source.
Both the 150 mg and 300 mg capsules remain available — there are no strengths without a source right now. Two manufacturers are reporting supply for both strengths, so a maker still has the capsules in each size you might need.
The reason behind this listing is that one manufacturer has discontinued making its version of these capsules. This has affected some specific product packages (about 44% of listed NDCs are marked unavailable), and the situation has lasted over a year. Even so, because another manufacturer continues to supply both strengths, this is not a sign that the medicine is gone from the market.
Here is what I suggest:
- Do not stop, skip, or change your dose on your own — keep taking rifampin as prescribed.
- Ask your pharmacy to order your strength from a manufacturer that still has supply; pharmacies can check wholesalers and other makers, including the same rifampin capsule from another company, though it may not be in local stock that day.
- If your exact package cannot be found, ask your prescriber or pharmacist about options.
Manufacturer contact numbers are listed on this page for reference; pharmacies usually handle those calls. This is general national information and may not match your local pharmacy's stock.
- Ask your pharmacy to check other companies’ versions, other strengths, package sizes, and nearby stores — the options below are a starting point.
- If this is part of an ongoing or essential regimen (for example HIV, seizure, heart, transplant, diabetes or mental-health medicines), arrange continued supply before you run out rather than rationing doses.
Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.
Where else can I get rifampin?
FDA shortages are company-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every company that lists rifampin capsules is necessarily short. Below are the other listings in the current FDA NDC Directory that are not reported in shortage: the same medicine from companies that haven’t reported a problem (the reporting companies are excluded), and other dosage forms. Some listings are repackagers, which relabel another company’s product. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.
Same medicine from other companies (not reporting a shortage)
Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from companies that have not filed a shortage with the FDA:
| Product | Strength | Form / route | Company | NDC |
|---|---|---|---|---|
| Rifampin | RIFAMPIN 300 mg/1 | Capsule · Oral | Major Pharmaceuticals | 00904-7315-61 |
| Rifampin | RIFAMPIN 150 mg/1 | Capsule · Oral | PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS | 24658-0801-30 |
| Rifampin | RIFAMPIN 300 mg/1 | Capsule · Oral | PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS | 24658-0802-60 |
| Rifampin | RIFAMPIN 300 mg/1 | Capsule · Oral | A-S Medication Solutions | 50090-5709-00 |
| Rifampin | RIFAMPIN 150 mg/1 | Capsule · Oral | American Health Packaging | 60687-0575-21 |
| Rifampin | RIFAMPIN 300 mg/1 | Capsule · Oral | American Health Packaging | 60687-0586-01 |
| Rifampin | RIFAMPIN 150 mg/1 | Capsule · Oral | Chartwell RX, LLC | 62135-0315-30 |
| Rifampin | RIFAMPIN 300 mg/1 | Capsule · Oral | Chartwell RX, LLC | 62135-0316-60 |
Other dosage forms of rifampin
A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:
Therapeutic equivalents & pricing 17 productsclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| rifampin 300 mg | Major | 100 capsules | $0.679 | AB | Availability likely |
| Rifampin 300 mg | PURACAP | 60 capsules | $0.679 | AB | Availability likely |
| Rifampin 300 mg | American | 100 capsules | $0.679 | AB | Availability likely |
| Rifampin 300 mg | ANI | 30 capsules | $0.679 | AB | Availability likely |
| Rifampin 300 mg | EPIC | 30 capsules | $0.680 | AB | Availability likely |
| Rifampin 300 mg | EPIC | 100 capsules | $0.680 | AB | Availability likely |
| rifampin 300 mg | Lupin | 100 capsules | $0.710 | AB | Discontinued |
| rifampin 150 mg | Lupin | 60 capsules | $0.825 | AB | Discontinued |
| Rifampin 150 mg | PURACAP | 30 capsules | $0.898 | AB | Availability likely |
| Rifampin 150 mg | EPIC | 30 capsules | $0.898 | AB | Availability likely |
| Rifampin 150 mg | American | 30 capsules | $0.898 | AB | Availability likely |
| Rifampin 150 mg | ANI | 30 capsules | $0.898 | AB | Availability likely |
| Rifampin 150 mg | Chartwell | 30 capsules | — | AB | FDA listed |
| Rifampin 150 mg | Coupler | 30 capsules | — | AB | FDA listed |
| rifampin 300 mg | A-S | 30 capsules | — | AB | FDA listed |
| Rifampin 300 mg | Chartwell | 60 capsules | — | AB | FDA listed |
| rifampin 300 mg | Bryant | 30 capsules | — | AB | FDA listed |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of rifampin — that fall in the same broad treatment class (antitubercular antibiotics) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Codes & classification for pharmacists and billers
Where does this data come from?
Other anti-infective shortages
Rifampin shortage FAQs
Is rifampin still in shortage?
Which strengths of rifampin are affected?
Why is rifampin in shortage?
Which rifampin products are affected?
When will rifampin be available again?
Can I still get rifampin somewhere?
What should I do if I take rifampin?
Still have a question about the rifampin shortage?
Ask a pharmacist about this shortage →View Rifampin Capsule on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (companies listing the same ingredient & form — the "other companies" the rating counts); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.