Rifampin
Generic name: Pronounced as (rif' am pin)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 04/15/2019
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Brand names of combination products
- Drug interactions
Why is this medication prescribed?
Rifampin is used with other medications to treat tuberculosis (TB; a serious infection that affects the lungs and sometimes other parts of the body). Rifampin is also used to treat some people who have Neisseria meningitidis (a type of bacteria that can cause a serious infection called meningitis) infections in their noses or throats. These people have not developed symptoms of the disease, and this treatment is used to prevent them from infecting other people. Rifampin should not be used to treat people who have developed symptoms of meningitis. Rifampin is in a class of medications called antimycobacterials. It works by killing the bacteria that cause infection.
Antibiotics such as rifampin will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
How should this medicine be used?
Rifampin comes as a capsule to take by mouth. It should be taken with a full glass of water on an empty stomach, 1 hour before or 2 hours after a meal. When rifampin is used to treat tuberculosis, it is taken once daily. When rifampin is used to prevent the spread of Neisseria meningitidis bacteria to other people, it is taken twice daily for 2 days or once daily for 4 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take rifampin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Tell your doctor or pharmacist if you cannot swallow the capsules. Your pharmacist can prepare a liquid for you to take instead.
If you are taking rifampin to treat tuberculosis, your doctor may tell you to take rifampin for several months or longer. Continue to take rifampin until you finish the prescription even if you feel better, and be careful not to miss doses. If you stop taking rifampin too soon, your infection may not be completely treated and the bacteria may become resistant to antibiotics. If you miss doses of rifampin, you may develop uncomfortable or serious symptoms when you begin to take the medication again.
Other uses for this medicine
Rifampin is also sometimes used to treat infections caused by other types of bacteria and to prevent infection in people who have been in close contact with a person who has certain serious bacterial infections. Talk to your doctor about the risks of using this medication for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking rifampin,
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tell your doctor and pharmacist if you are allergic to rifampin, rifabutin (Mycobutin), rifapentine (Priftin), any other medications, or any of the ingredients in rifampin capsules. Ask your doctor or pharmacist for a list of the ingredients.
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tell your doctor if you are taking any of the following medications: atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), praziquantel (Biltricide), saquinavir (Invirase), tipranavir (Aptivus), or ritonavir (Norvir) and saquinavir (Invirase) taken together. Your doctor will probably tell you not to take rifampin if you are taking any of these medications. If you are taking rifampin and need to take praziquantal (Biltricide), you should wait at least 4 weeks after you stop taking rifampin before you begin to take praziquantel.
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tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); antifungals such as fluconazole (Diflucan), itraconazole (Onmel, Sporanox), and ketoconazole; atovaquone (Mepron, in Malarone); barbiturates such as phenobarbital; beta blockers such as atenolol (Tenormin), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal, Innopran); calcium channel blockers such as diltiazem (Cardizem, Cartia, Tiazac), nifedipine (Adalat, Procardia), and verapamil (Calan, Verelan); chloramphenicol; clarithromycin (Biaxin); cyclosporine (Gengraf, Neoral, Sandimmune); daclatasvir (Daklinza); dapsone; diazepam (Valium); doxycycline (Monodox, Oracea, Vibramycin); efavirenz (Sustiva); enalapril (Vaseretic); fluoroquinolone antibiotics such as ciprofloxacin (Cipro) and moxifloxacin (Avelox); gemfibrozil (Lopid); haloperidol (Haldol); hormonal contraceptives (birth control pills, patches, rings, or injections); hormone replacement therapy (HRT); indinavir (Crixivan); irinotecan (Camptosar); isoniazid (in Rifater, Rifamate); levothyroxine (Levoxyl, Synthroid, Tirosint); losartan (Cozaar); medications for irregular heartbeat such as digoxin (Lanoxin), disopyramide (Norpace), mexiletine, propafenone (Rythmol), and quinidine (in Nuedexta); medications for seizures such as phenytoin (Dilantin, Phenytek); methadone (Dolophine, Methadose); narcotic medications for pain such as oxycodone (Oxaydo, Xtampza) and morphine (Kadian); ondansetron (Zofran, Zuplenz); oral medications for diabetes such as glipizide (Glucotrol), glyburide (Diabeta), and rosiglitazone (Avandia); probenecid (Probalan); quinine (Qualquin); simvastatin (Flolipid, Zocor), steroids such as dexamethasone (Decadron), methylprednisolone (Medrol), and prednisone; sofosbuvir (Sovaldi); tamoxifen (Soltamox); toremifene (Fareston); trimethoprim and sulfamethoxazole (Bactrim, Septra); tacrolimus(Prograf); theophylline (Elixophyllin, Theo-24); tricyclic antidepressants such as amitriptyline and nortriptyline (Pamelor); zidovudine (Retrovir, in Trizivir), and zolpidem (Ambien). Many other medications may interact with rifampin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
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if you are taking antacids, take rifampin at least 1 hour before you take the antacids.
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tell your doctor if you are taking or using hormonal contraceptives (birth control pills, patches, rings, implants, and injections). Rifampin can decrease the effectiveness of hormonal contraceptives. You should use another method of birth control while taking this medication. Talk to your doctor about birth control while taking rifampin.
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tell your doctor if you have or have ever had diabetes, porphyria (condition in which certain natural substances build up in the body and may cause stomach pain, changes in thinking and behavior, or other symptoms), any condition that affects your adrenal gland (small gland next to the kidney that produces important natural substances) or liver disease.
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tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking rifampin, call your doctor.
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tell your doctor if you wear soft contact lenses. Rifampin may cause permanent red stains on your contact lenses if you wear them during your treatment with rifampin.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Do not miss doses of rifampin. Missing doses may increase the risk that you will experience serious side effects. If you do miss a dose, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and call your doctor. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
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Rifampin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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temporary discoloration (yellow, reddish-orange, or brown color) of your skin, teeth, saliva, urine, stool, sweat, and tears)
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itching
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flushing
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headache
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drowsiness
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dizziness
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lack of coordination
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difficulty concentrating
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confusion
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changes in behavior
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muscle weakness
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numbness
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pain in the arms, hands, feet, or legs
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heartburn
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stomach cramps
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loss of appetite
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nausea
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vomiting
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diarrhea
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gas
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painful or irregular menstrual periods
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vision changes
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Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:
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watery or bloody stools, stomach cramps, or fever during treatment or for up to two or more months after stopping treatment
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rash; hives; fever; chills; swelling of the eyes, face, lips, tongue, or throat; difficulty swallowing or breathing; shortness of breath; wheezing; swollen lymph nodes; sore throat; pink eye; flu- like symptoms; unusual bleeding or bruising; or joint swelling or pain
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nausea, vomiting, loss of appetite, dark urine, or yellowing of the skin or eyes
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
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Rifampin may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include the following:
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nausea
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vomiting
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stomach pain
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itching
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headache
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loss of consciousness
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yellowing of the skin or eyes
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reddish brown discoloration of the skin, saliva, urine, feces, sweat, and tears
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tenderness in the upper right part of the stomach
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swelling of the eyes or face
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fast or irregular heartbeat
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seizures
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to rifampin.
Before having any laboratory test, including drug screening tests, tell the laboratory personnel that you are taking rifampin. Rifampin may cause the results of certain drug screening tests to be positive even though you have not taken the drugs.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Repaglinide | Repaglinide The serum concentration of Repaglinide can be decreased when it is combined with Rifampicin. |
Montelukast | Montelukast The metabolism of Montelukast can be increased when combined with Rifampicin. |
Leflunomide | Leflunomide The serum concentration of teriflunomide (A77 1726), an active metabolite of Leflunomide, can be increased when used in combination with Rifampicin. |
Nevirapine | Nevirapine The metabolism of Nevirapine can be increased when combined with Rifampicin. |
Atorvastatin | Atorvastatin The metabolism of Atorvastatin can be increased when combined with Rifampicin. |
Aminophylline | Aminophylline The metabolism of Aminophylline can be increased when combined with Rifampicin. |
Anagrelide | Anagrelide The metabolism of Anagrelide can be increased when combined with Rifampicin. |
Calcium Carbonate | Calcium Carbonate Calcium carbonate can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Cilostazol | Cilostazol The metabolism of Cilostazol can be increased when combined with Rifampicin. |
Clopidogrel | Clopidogrel The therapeutic efficacy of Clopidogrel can be increased when used in combination with Rifampicin. |
Erythromycin and Sulfisoxazole | Erythromycin and Sulfisoxazole The metabolism of Erythromycin can be increased when combined with Rifampicin. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) The metabolism of Conjugated estrogens can be increased when combined with Rifampicin. |
Fenofibrate | Fenofibrate The metabolism of Fenofibrate can be increased when combined with Rifampicin. |
Guanfacine | Guanfacine The metabolism of Guanfacine can be increased when combined with Rifampicin. |
Magnesium Hydroxide | Magnesium Hydroxide Magnesium hydroxide can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Magnesium Oxide | Magnesium Oxide Magnesium oxide can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Mycophenolate | Mycophenolate The metabolism of Mycophenolic acid can be increased when combined with Rifampicin. |
Paregoric | Paregoric The metabolism of Morphine can be increased when combined with Rifampicin. |
Penbutolol | Penbutolol The metabolism of Acebutolol can be increased when combined with Rifampicin. |
Ranitidine | Ranitidine Ranitidine can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Reserpine | Reserpine The risk or severity of liver damage can be increased when Reserpine is combined with Rifampicin. |
Sumatriptan | Sumatriptan The excretion of Sumatriptan can be decreased when combined with Rifampicin. |
Tacrolimus | Tacrolimus The metabolism of Tacrolimus can be increased when combined with Rifampicin. |
Tizanidine | Tizanidine The metabolism of Tizanidine can be increased when combined with Rifampicin. |
Triamcinolone | Triamcinolone The metabolism of Triamcinolone can be increased when combined with Rifampicin. |
Zolmitriptan | Zolmitriptan The metabolism of Zolmitriptan can be increased when combined with Rifampicin. |
Famotidine Injection | Famotidine Injection Famotidine can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Fluconazole Injection | Fluconazole Injection Rifampicin may increase the excretion rate of Fluconazole which could result in a lower serum level and potentially a reduction in efficacy. |
Levofloxacin Injection | Levofloxacin Injection The excretion of Levofloxacin can be decreased when combined with Rifampicin. |
Meperidine Injection | Meperidine Injection The metabolism of Meperidine can be increased when combined with Rifampicin. |
Metoclopramide Injection | Metoclopramide Injection The metabolism of Metoclopramide can be increased when combined with Rifampicin. |
Metronidazole Injection | Metronidazole Injection The metabolism of Metronidazole can be increased when combined with Rifampicin. |
Morphine Injection | Morphine Injection The metabolism of Morphine can be increased when combined with Rifampicin. |
Zidovudine Injection | Zidovudine Injection The metabolism of Zidovudine can be increased when combined with Rifampicin. |
Cyclosporine | Cyclosporine The metabolism of Cyclosporine can be increased when combined with Rifampicin. |
Ondansetron | Ondansetron The metabolism of Ondansetron can be increased when combined with Rifampicin. |
Torsemide | Torsemide The metabolism of Torasemide can be increased when combined with Rifampicin. |
Olanzapine | Olanzapine The metabolism of Olanzapine can be increased when combined with Rifampicin. |
Alosetron | Alosetron The metabolism of Alosetron can be increased when combined with Rifampicin. |
Dofetilide | Dofetilide The metabolism of Dofetilide can be increased when combined with Rifampicin. |
Entacapone | Entacapone The metabolism of Entacapone can be increased when combined with Rifampicin. |
Hydroxychloroquine | Hydroxychloroquine The metabolism of Hydroxychloroquine can be increased when combined with Rifampicin. |
Pantoprazole | Pantoprazole Pantoprazole can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Telmisartan | Telmisartan Rifampicin may decrease the excretion rate of Telmisartan which could result in a higher serum level. |
Zaleplon | Zaleplon The metabolism of Zaleplon can be increased when combined with Rifampicin. |
Linezolid | Linezolid The therapeutic efficacy of Linezolid can be decreased when used in combination with Rifampicin. |
Trimipramine | Trimipramine The serum concentration of Trimipramine can be decreased when it is combined with Rifampicin. |
Tenofovir | Tenofovir The metabolism of Rifampicin can be increased when combined with Tenofovir. |
Sirolimus | Sirolimus The metabolism of Sirolimus can be increased when combined with Rifampicin. |
Dutasteride | Dutasteride The metabolism of Dutasteride can be increased when combined with Rifampicin. |
Eplerenone | Eplerenone The metabolism of Eplerenone can be increased when combined with Rifampicin. |
Escitalopram | Escitalopram The metabolism of Escitalopram can be increased when combined with Rifampicin. |
Olmesartan | Olmesartan The risk or severity of liver damage can be increased when Olmesartan is combined with Rifampicin. |
Zonisamide | Zonisamide The metabolism of Zonisamide can be increased when combined with Rifampicin. |
Aripiprazole | Aripiprazole The metabolism of Aripiprazole can be increased when combined with Rifampicin. |
Ezetimibe | Ezetimibe The metabolism of Ezetimibe can be increased when combined with Rifampicin. |
Atazanavir | Atazanavir The metabolism of Rifampicin can be increased when combined with Atazanavir. |
Almotriptan | Almotriptan The metabolism of Almotriptan can be increased when combined with Rifampicin. |
Rosuvastatin | Rosuvastatin The metabolism of Rifampicin can be increased when combined with Rosuvastatin. |
Vardenafil | Vardenafil The metabolism of Vardenafil can be increased when combined with Rifampicin. |
Aprepitant | Aprepitant The metabolism of Aprepitant can be increased when combined with Rifampicin. |
Tadalafil | Tadalafil The metabolism of Tadalafil can be increased when combined with Rifampicin. |
Frovatriptan | Frovatriptan The metabolism of Frovatriptan can be increased when combined with Rifampicin. |
Progesterone | Progesterone The metabolism of Rifampicin can be increased when combined with Progesterone. |
Apomorphine Injection | Apomorphine Injection The metabolism of Apomorphine can be increased when combined with Rifampicin. |
Duloxetine | Duloxetine The metabolism of Duloxetine can be increased when combined with Rifampicin. |
Norethindrone | Norethindrone The metabolism of Rifampicin can be increased when combined with Norethisterone. |
Tinidazole | Tinidazole Rifampicin may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
Bosentan | Bosentan The serum concentration of Bosentan can be decreased when it is combined with Rifampicin. |
Cefditoren | Cefditoren The excretion of Cefdinir can be decreased when combined with Rifampicin. |
Cinacalcet | Cinacalcet The metabolism of Cinacalcet can be increased when combined with Rifampicin. |
Erlotinib | Erlotinib The metabolism of Erlotinib can be increased when combined with Rifampicin. |
Eszopiclone | Eszopiclone The serum concentration of Eszopiclone can be decreased when it is combined with Rifampicin. |
Voriconazole | Voriconazole The metabolism of Voriconazole can be increased when combined with Rifampicin. |
Entecavir | Entecavir The metabolism of Entecavir can be increased when combined with Rifampicin. |
Ramelteon | Ramelteon The metabolism of Ramelteon can be increased when combined with Rifampicin. |
Fentanyl | Fentanyl The metabolism of Fentanyl can be increased when combined with Rifampicin. |
Deferasirox | Deferasirox The metabolism of Deferasirox can be increased when combined with Rifampicin. |
Tipranavir | Tipranavir Rifampicin may decrease the excretion rate of Tipranavir which could result in a higher serum level. |
Felbamate | Felbamate The metabolism of Felbamate can be increased when combined with Rifampicin. |
Ranolazine | Ranolazine The metabolism of Rifampicin can be increased when combined with Ranolazine. |
Rasagiline | Rasagiline The metabolism of Rasagiline can be increased when combined with Rifampicin. |
Imatinib | Imatinib The metabolism of Imatinib can be increased when combined with Rifampicin. |
Sitagliptin | Sitagliptin The metabolism of Sitagliptin can be increased when combined with Rifampicin. |
Gefitinib | Gefitinib The metabolism of Gefitinib can be increased when combined with Rifampicin. |
Paliperidone | Paliperidone The serum concentration of Paliperidone can be decreased when it is combined with Rifampicin. |
Exemestane | Exemestane The metabolism of Exemestane can be increased when combined with Rifampicin. |
Bortezomib | Bortezomib The metabolism of Bortezomib can be increased when combined with Rifampicin. |
Clofarabine Injection | Clofarabine Injection The excretion of Clofarabine can be decreased when combined with Rifampicin. |
Fulvestrant Injection | Fulvestrant Injection The metabolism of Fulvestrant can be increased when combined with Rifampicin. |
Primaquine | Primaquine The metabolism of Primaquine can be increased when combined with Rifampicin. |
Pemetrexed Injection | Pemetrexed Injection The metabolism of Pemetrexed can be increased when combined with Rifampicin. |
Retapamulin | Retapamulin The metabolism of Retapamulin can be increased when combined with Rifampicin. |
Sorafenib | Sorafenib The metabolism of Sorafenib can be increased when combined with Rifampicin. |
Sunitinib | Sunitinib The metabolism of Sunitinib can be increased when combined with Rifampicin. |
Lapatinib | Lapatinib The metabolism of Lapatinib can be increased when combined with Rifampicin. |
Dasatinib | Dasatinib The metabolism of Dasatinib can be increased when combined with Rifampicin. |
Mexiletine | Mexiletine The metabolism of Mexiletine can be increased when combined with Rifampicin. |
Ivermectin | Ivermectin The excretion of Rifampicin can be decreased when combined with Ivermectin. |
Temsirolimus | Temsirolimus The metabolism of Temsirolimus can be increased when combined with Rifampicin. |
Maraviroc | Maraviroc The metabolism of Maraviroc can be increased when combined with Rifampicin. |
Nilotinib | Nilotinib The metabolism of Nilotinib can be increased when combined with Rifampicin. |
Raltegravir | Raltegravir The serum concentration of Raltegravir can be decreased when it is combined with Rifampicin. |
Budesonide | Budesonide Rifampicin may decrease the excretion rate of Budesonide which could result in a higher serum level. |
Chloramphenicol Injection | Chloramphenicol Injection The metabolism of Chloramphenicol can be increased when combined with Rifampicin. |
Doripenem Injection | Doripenem Injection The excretion of Doripenem can be decreased when combined with Rifampicin. |
Etravirine | Etravirine The metabolism of Etravirine can be increased when combined with Rifampicin. |
Nebivolol | Nebivolol The metabolism of Nebivolol can be increased when combined with Rifampicin. |
Tretinoin | Tretinoin The metabolism of Tretinoin can be increased when combined with Rifampicin. |
Bendamustine Injection | Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Rifampicin. |
Leucovorin Injection | Leucovorin Injection The excretion of Leucovorin can be decreased when combined with Rifampicin. |
Flecainide | Flecainide The metabolism of Flecainide can be increased when combined with Rifampicin. |
Ixabepilone Injection | Ixabepilone Injection The metabolism of Ixabepilone can be increased when combined with Rifampicin. |
Irinotecan Injection | Irinotecan Injection The metabolism of Irinotecan can be increased when combined with Rifampicin. |
Praziquantel | Praziquantel The metabolism of Praziquantel can be increased when combined with Rifampicin. |
Rufinamide | Rufinamide The metabolism of Rifampicin can be increased when combined with Rufinamide. |
Midazolam | Midazolam The metabolism of Midazolam can be increased when combined with Rifampicin. |
Naltrexone Injection | Naltrexone Injection The metabolism of Naltrexone can be increased when combined with Rifampicin. |
Eltrombopag | Eltrombopag The metabolism of Eltrombopag can be increased when combined with Rifampicin. |
Milnacipran | Milnacipran The metabolism of Milnacipran can be increased when combined with Rifampicin. |
Dexlansoprazole | Dexlansoprazole Dexlansoprazole can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Betaxolol | Betaxolol The metabolism of Betaxolol can be increased when combined with Rifampicin. |
Iloperidone | Iloperidone The metabolism of Iloperidone can be increased when combined with Rifampicin. |
Lacosamide | Lacosamide The metabolism of Rifampicin can be increased when combined with Lacosamide. |
Everolimus | Everolimus The metabolism of Everolimus can be increased when combined with Rifampicin. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) The serum concentration of Tolvaptan can be decreased when it is combined with Rifampicin. |
Dronedarone | Dronedarone The metabolism of Rifampicin can be increased when combined with Dronedarone. |
Saxagliptin | Saxagliptin The metabolism of Saxagliptin can be increased when combined with Rifampicin. |
Romidepsin Injection | Romidepsin Injection The serum concentration of Romidepsin can be increased when it is combined with Rifampicin. |
Tapentadol | Tapentadol The metabolism of Tapentadol can be increased when combined with Rifampicin. |
Topotecan | Topotecan The serum concentration of Topotecan can be decreased when it is combined with Rifampicin. |
Pazopanib | Pazopanib The metabolism of Pazopanib can be increased when combined with Rifampicin. |
Asenapine | Asenapine The metabolism of Asenapine can be increased when combined with Rifampicin. |
Pitavastatin | Pitavastatin The excretion of Pitavastatin can be decreased when combined with Rifampicin. |
Albendazole | Albendazole The metabolism of Albendazole can be increased when combined with Rifampicin. |
Ulipristal | Ulipristal The metabolism of Ulipristal can be increased when combined with Rifampicin. |
Levonorgestrel | Levonorgestrel The therapeutic efficacy of Levonorgestrel can be decreased when used in combination with Rifampicin. |
Fingolimod | Fingolimod The metabolism of Fingolimod can be increased when combined with Rifampicin. |
Cabazitaxel Injection | Cabazitaxel Injection The serum concentration of Rifampicin can be decreased when it is combined with Cabazitaxel. |
Acetaminophen Injection | Acetaminophen Injection Rifampicin may increase the hepatotoxic activities of Acetaminophen. |
Vilazodone | Vilazodone The metabolism of Vilazodone can be increased when combined with Rifampicin. |
Busulfan Injection | Busulfan Injection The metabolism of Busulfan can be increased when combined with Rifampicin. |
Roflumilast | Roflumilast The metabolism of Rifampicin can be increased when combined with Roflumilast. |
Linagliptin | Linagliptin The serum concentration of Linagliptin can be decreased when it is combined with Rifampicin. |
Rilpivirine | Rilpivirine The excretion of Rifampicin can be decreased when combined with Rilpivirine. |
Telaprevir | Telaprevir The excretion of Glecaprevir can be decreased when combined with Rifampicin. |
Cyclophosphamide Injection | Cyclophosphamide Injection The metabolism of Cyclophosphamide can be increased when combined with Rifampicin. |
Abiraterone | Abiraterone The metabolism of Abiraterone can be increased when combined with Rifampicin. |
Rivaroxaban | Rivaroxaban The metabolism of Rivaroxaban can be increased when combined with Rifampicin. |
Brentuximab Vedotin Injection | Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be decreased when it is combined with Rifampicin. |
Ruxolitinib | Ruxolitinib The metabolism of Ruxolitinib can be increased when combined with Rifampicin. |
Vandetanib | Vandetanib The metabolism of Vandetanib can be increased when combined with Rifampicin. |
Clobazam | Clobazam The metabolism of Clobazam can be increased when combined with Rifampicin. |
Vemurafenib | Vemurafenib The metabolism of Vemurafenib can be increased when combined with Rifampicin. |
Ivacaftor | Ivacaftor The serum concentration of Ivacaftor can be decreased when it is combined with Rifampicin. |
Axitinib | Axitinib The metabolism of Rifampicin can be increased when combined with Axitinib. |
Crizotinib | Crizotinib The metabolism of Crizotinib can be increased when combined with Rifampicin. |
Cabergoline | Cabergoline The metabolism of Cabergoline can be increased when combined with Rifampicin. |
Naloxone Injection | Naloxone Injection The metabolism of Naloxone can be increased when combined with Rifampicin. |
Ambrisentan | Ambrisentan The metabolism of Ambrisentan can be decreased when combined with Rifampicin. |
Ezogabine | Ezogabine The metabolism of Tiagabine can be increased when combined with Rifampicin. |
Carfilzomib Injection | Carfilzomib Injection The serum concentration of Carfilzomib can be decreased when it is combined with Rifampicin. |
Enzalutamide | Enzalutamide The metabolism of Enzalutamide can be increased when combined with Rifampicin. |
Regorafenib | Regorafenib The metabolism of Regorafenib can be decreased when combined with Rifampicin. |
Bosutinib | Bosutinib The metabolism of Bosutinib can be increased when combined with Rifampicin. |
Cabozantinib (thyroid cancer) | Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be increased when combined with Rifampicin. |
Ponatinib | Ponatinib The metabolism of Ponatinib can be increased when combined with Rifampicin. |
Pomalidomide | Pomalidomide The serum concentration of Pomalidomide can be decreased when it is combined with Rifampicin. |
Ado-trastuzumab Emtansine Injection | Ado-trastuzumab Emtansine Injection The serum concentration of Trastuzumab emtansine can be decreased when it is combined with Rifampicin. |
Apixaban | Apixaban The metabolism of Apixaban can be increased when combined with Rifampicin. |
Canagliflozin | Canagliflozin The serum concentration of Canagliflozin can be decreased when it is combined with Rifampicin. |
Dabrafenib | Dabrafenib The metabolism of Dabrafenib can be increased when combined with Rifampicin. |
Dolutegravir | Dolutegravir The serum concentration of Dolutegravir can be decreased when it is combined with Rifampicin. |
Afatinib | Afatinib The serum concentration of Afatinib can be decreased when it is combined with Rifampicin. |
Levomilnacipran | Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Rifampicin. |
Vortioxetine | Vortioxetine The metabolism of Vortioxetine can be increased when combined with Rifampicin. |
Perampanel | Perampanel The metabolism of Perampanel can be increased when combined with Rifampicin. |
Ibrutinib | Ibrutinib The metabolism of Ibrutinib can be increased when combined with Rifampicin. |
Lomitapide | Lomitapide The metabolism of Lomitapide can be increased when combined with Rifampicin. |
Ketorolac Injection | Ketorolac Injection The metabolism of Ketorolac can be increased when combined with Rifampicin. |
Simeprevir | Simeprevir The risk or severity of liver damage can be increased when Rifampicin is combined with Simeprevir. |
Sofosbuvir | Sofosbuvir The serum concentration of Sofosbuvir can be decreased when it is combined with Rifampicin. |
Dapagliflozin | Dapagliflozin The metabolism of Dapagliflozin can be increased when combined with Rifampicin. |
Apremilast | Apremilast The metabolism of Apremilast can be increased when combined with Rifampicin. |
Ceritinib | Ceritinib The metabolism of Rifampicin can be increased when combined with Ceritinib. |
Eslicarbazepine | Eslicarbazepine The metabolism of Rifampicin can be increased when combined with Eslicarbazepine. |
Belinostat Injection | Belinostat Injection The metabolism of Belinostat can be increased when combined with Rifampicin. |
Idelalisib | Idelalisib The metabolism of Idelalisib can be increased when combined with Rifampicin. |
Testosterone Injection | Testosterone Injection The metabolism of Testosterone can be increased when combined with Rifampicin. |
Vorapaxar | Vorapaxar The metabolism of Vorapaxar can be increased when combined with Rifampicin. |
Hydrocodone | Hydrocodone The metabolism of Hydrocodone can be increased when combined with Rifampicin. |
Suvorexant | Suvorexant The metabolism of Suvorexant can be increased when combined with Rifampicin. |
Olaparib | Olaparib The metabolism of Olaparib can be increased when combined with Rifampicin. |
Caspofungin Injection | Caspofungin Injection The serum concentration of Caspofungin can be decreased when it is combined with Rifampicin. |
Tasimelteon | Tasimelteon The metabolism of Rifampicin can be increased when combined with Tasimelteon. |
Riociguat | Riociguat The metabolism of Riociguat can be increased when combined with Rifampicin. |
Pirfenidone | Pirfenidone The serum concentration of Pirfenidone can be decreased when it is combined with Rifampicin. |
Nintedanib | Nintedanib The serum concentration of Rifampicin can be decreased when it is combined with Nintedanib. |
Risperidone Injection | Risperidone Injection The metabolism of Risperidone can be increased when combined with Rifampicin. |
Palbociclib | Palbociclib The metabolism of Palbociclib can be increased when combined with Rifampicin. |
Lenvatinib | Lenvatinib The risk or severity of liver damage can be increased when Rifampicin is combined with Lenvatinib. |
Panobinostat | Panobinostat The metabolism of Panobinostat can be increased when combined with Rifampicin. |
Haloperidol Injection | Haloperidol Injection The metabolism of Haloperidol can be increased when combined with Rifampicin. |
Sonidegib | Sonidegib The metabolism of Sonidegib can be increased when combined with Rifampicin. |
Daclatasvir | Daclatasvir The metabolism of Rifampicin can be increased when combined with Daclatasvir. |
Brexpiprazole | Brexpiprazole The metabolism of Brexpiprazole can be increased when combined with Rifampicin. |
Ziprasidone Injection | Ziprasidone Injection The metabolism of Rifampicin can be increased when combined with Ziprasidone. |
Eluxadoline | Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Rifampicin. |
Cobimetinib | Cobimetinib The metabolism of Rifampicin can be increased when combined with Cobimetinib. |
Trabectedin Injection | Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Rifampicin. |
Osimertinib | Osimertinib The metabolism of Osimertinib can be increased when combined with Rifampicin. |
Alectinib | Alectinib The metabolism of Alectinib can be increased when combined with Rifampicin. |
Ixazomib | Ixazomib The metabolism of Ixazomib can be increased when combined with Rifampicin. |
Dexamethasone Injection | Dexamethasone Injection The metabolism of Dexamethasone can be increased when combined with Rifampicin. |
Venetoclax | Venetoclax The metabolism of Venetoclax can be increased when combined with Rifampicin. |
Cobicistat | Cobicistat The metabolism of Rifampicin can be increased when combined with Cobicistat. |
Selexipag | Selexipag The metabolism of Selexipag can be increased when combined with Rifampicin. |
Obeticholic Acid | Obeticholic Acid The risk or severity of adverse effects can be increased when Rifampicin is combined with Obeticholic acid. |
Furosemide Injection | Furosemide Injection The metabolism of Furosemide can be increased when combined with Rifampicin. |
Rucaparib | Rucaparib The metabolism of Rifampicin can be increased when combined with Rucaparib. |
Ribociclib | Ribociclib The metabolism of Rifampicin can be increased when combined with Ribociclib. |
Brigatinib | Brigatinib The metabolism of Brigatinib can be increased when combined with Rifampicin. |
Doxepin (Insomnia) | Doxepin (Insomnia) The metabolism of Doxepin can be increased when combined with Rifampicin. |
Deutetrabenazine | Deutetrabenazine The metabolism of Deutetrabenazine can be increased when combined with Rifampicin. |
Valbenazine | Valbenazine The metabolism of Valbenazine can be increased when combined with Rifampicin. |
Deflazacort | Deflazacort The serum concentration of Deflazacort can be decreased when it is combined with Rifampicin. |
Edaravone Injection | Edaravone Injection The excretion of Edaravone can be decreased when combined with Rifampicin. |
Midostaurin | Midostaurin The metabolism of Midostaurin can be increased when combined with Rifampicin. |
Neratinib | Neratinib The metabolism of Neratinib can be increased when combined with Rifampicin. |
Enasidenib | Enasidenib The metabolism of Rifampicin can be increased when combined with Enasidenib. |
Inotuzumab Ozogamicin Injection | Inotuzumab Ozogamicin Injection The serum concentration of Inotuzumab ozogamicin can be decreased when it is combined with Rifampicin. |
Aprepitant/Fosaprepitant Injection | Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Rifampicin. |
Copanlisib Injection | Copanlisib Injection The metabolism of Copanlisib can be increased when combined with Rifampicin. |
Delafloxacin | Delafloxacin The metabolism of Delafloxacin can be increased when combined with Rifampicin. |
Abemaciclib | Abemaciclib The metabolism of Abemaciclib can be increased when combined with Rifampicin. |
Acalabrutinib | Acalabrutinib The metabolism of Acalabrutinib can be increased when combined with Rifampicin. |
Letermovir | Letermovir The risk or severity of liver damage can be increased when Rifampicin is combined with Letermovir. |
Ertugliflozin | Ertugliflozin The metabolism of Ertugliflozin can be increased when combined with Rifampicin. |
Buprenorphine Injection | Buprenorphine Injection The metabolism of Buprenorphine can be increased when combined with Rifampicin. |
Apalutamide | Apalutamide The metabolism of Apalutamide can be increased when combined with Rifampicin. |
Penicillamine | Penicillamine The excretion of Penicillamine can be decreased when combined with Rifampicin. |
Fostamatinib | Fostamatinib The metabolism of Fostamatinib can be decreased when combined with Rifampicin. |
Baricitinib | Baricitinib The metabolism of Rifampicin can be increased when combined with Baricitinib. |
Sodium Zirconium Cyclosilicate | Sodium Zirconium Cyclosilicate Sodium zirconium cyclosilicate can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Lofexidine | Lofexidine The metabolism of Lofexidine can be increased when combined with Rifampicin. |
Binimetinib | Binimetinib The serum concentration of Binimetinib can be decreased when it is combined with Rifampicin. |
Ivosidenib | Ivosidenib The metabolism of Ivosidenib can be increased when combined with Rifampicin. |
Elagolix | Elagolix The metabolism of Elagolix can be increased when combined with Rifampicin. |
Doravirine | Doravirine The metabolism of Doravirine can be increased when combined with Rifampicin. |
Cannabidiol | Cannabidiol The metabolism of Cannabidiol can be increased when combined with Rifampicin. |
Dacomitinib | Dacomitinib The metabolism of Dacomitinib can be increased when combined with Rifampicin. |
Duvelisib | Duvelisib The metabolism of Rifampicin can be increased when combined with Duvelisib. |
Stiripentol | Stiripentol The metabolism of Stiripentol can be increased when combined with Rifampicin. |
Talazoparib | Talazoparib The serum concentration of Talazoparib can be decreased when it is combined with Rifampicin. |
Gilteritinib | Gilteritinib The metabolism of Rifampicin can be increased when combined with Gilteritinib. |
Glasdegib | Glasdegib The metabolism of Glasdegib can be increased when combined with Rifampicin. |
Lorlatinib | Lorlatinib The metabolism of Lorlatinib can be increased when combined with Rifampicin. |
Paclitaxel (with albumin) Injection | Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be increased when combined with Rifampicin. |
Rifamycin | Rifamycin The excretion of Rifampicin can be decreased when combined with Rifamycin. |
Prucalopride | Prucalopride The metabolism of Prucalopride can be increased when combined with Rifampicin. |
Siponimod | Siponimod The therapeutic efficacy of Siponimod can be decreased when used in combination with Rifampicin. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic The metabolism of Acyclovir can be increased when combined with Rifampicin. |
Erdafitinib | Erdafitinib The metabolism of Erdafitinib can be increased when combined with Rifampicin. |
Esomeprazole Injection | Esomeprazole Injection The serum concentration of Esomeprazole can be decreased when it is combined with Rifampicin. |
Alpelisib | Alpelisib The serum concentration of Alpelisib can be decreased when it is combined with Rifampicin. |
Polatuzumab vedotin-piiq Injection | Polatuzumab vedotin-piiq Injection The risk or severity of adverse effects can be decreased when Rifampicin is combined with Polatuzumab vedotin. |
Selinexor | Selinexor The excretion of Rifampicin can be decreased when combined with Selinexor. |
Darolutamide | Darolutamide The serum concentration of Darolutamide can be decreased when it is combined with Rifampicin. |
Triclabendazole | Triclabendazole The metabolism of Triclabendazole can be increased when combined with Rifampicin. |
Entrectinib | Entrectinib The metabolism of Entrectinib can be increased when combined with Rifampicin. |
Pexidartinib | Pexidartinib The metabolism of Pexidartinib can be increased when combined with Rifampicin. |
Upadacitinib | Upadacitinib The metabolism of Upadacitinib can be increased when combined with Rifampicin. |
Istradefylline | Istradefylline The serum concentration of Istradefylline can be decreased when it is combined with Rifampicin. |
Pitolisant | Pitolisant The metabolism of Pitolisant can be increased when combined with Rifampicin. |
Fedratinib | Fedratinib The metabolism of Rifampicin can be increased when combined with Fedratinib. |
Lefamulin | Lefamulin The metabolism of Lefamulin can be increased when combined with Rifampicin. |
Phenytoin Injection | Phenytoin Injection The serum concentration of Phenytoin can be decreased when it is combined with Rifampicin. |
Fosphenytoin Injection | Fosphenytoin Injection The serum concentration of Fosphenytoin can be decreased when it is combined with Rifampicin. |
Zanubrutinib | Zanubrutinib The metabolism of Zanubrutinib can be increased when combined with Rifampicin. |
Voxelotor | Voxelotor The serum concentration of Voxelotor can be decreased when it is combined with Rifampicin. |
Lumateperone | Lumateperone The serum concentration of Lumateperone can be decreased when it is combined with Rifampicin. |
Ubrogepant | Ubrogepant The serum concentration of Ubrogepant can be decreased when it is combined with Rifampicin. |
Tazemetostat | Tazemetostat The metabolism of Tazemetostat can be increased when combined with Rifampicin. |
Bempedoic Acid | Bempedoic Acid The excretion of Bempedoic acid can be decreased when combined with Rifampicin. |
Cenobamate | Cenobamate The metabolism of Cenobamate can be increased when combined with Rifampicin. |
Pemigatinib | Pemigatinib The metabolism of Pemigatinib can be increased when combined with Rifampicin. |
Ozanimod | Ozanimod The metabolism of Ozanimod can be increased when combined with Rifampicin. |
Selumetinib | Selumetinib The serum concentration of Selumetinib can be decreased when it is combined with Rifampicin. |
Rimegepant | Rimegepant The metabolism of Rimegepant can be increased when combined with Rifampicin. |
Tucatinib | Tucatinib The metabolism of Tucatinib can be increased when combined with Rifampicin. |
Remdesivir Injection | Remdesivir Injection The excretion of Remdesivir can be decreased when combined with Rifampicin. |
Sacituzumab govitecan-hziy Injection | Sacituzumab govitecan-hziy Injection The serum concentration of Sacituzumab govitecan can be decreased when it is combined with Rifampicin. |
Ripretinib | Ripretinib The serum concentration of Ripretinib can be decreased when it is combined with Rifampicin. |
Selpercatinib | Selpercatinib The serum concentration of Selpercatinib can be decreased when it is combined with Rifampicin. |
Capmatinib | Capmatinib The serum concentration of Capmatinib can be decreased when it is combined with Rifampicin. |
Lemborexant | Lemborexant The serum concentration of Lemborexant can be decreased when it is combined with Rifampicin. |
Fenfluramine | Fenfluramine The serum concentration of Fenfluramine can be decreased when it is combined with Rifampicin. |
Fostemsavir | Fostemsavir The serum concentration of Fostemsavir can be decreased when it is combined with Rifampicin. |
Lurbinectedin Injection | Lurbinectedin Injection The serum concentration of Lurbinectedin can be decreased when it is combined with Rifampicin. |
Belantamab Mafodotin-blmf Injection | Belantamab Mafodotin-blmf Injection Rifampicin may decrease the excretion rate of Belantamab mafodotin which could result in a higher serum level. |
Pralsetinib | Pralsetinib The serum concentration of Pralsetinib can be decreased when it is combined with Rifampicin. |
Relugolix | Relugolix The serum concentration of Relugolix can be decreased when it is combined with Rifampicin. |
Progestin-Only (drospirenone) Oral Contraceptives | Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Rifampicin can be increased when combined with Drospirenone. |
Theophylline | Theophylline The metabolism of Theophylline can be increased when combined with Rifampicin. |
Indomethacin | Indomethacin The excretion of Indomethacin can be decreased when combined with Rifampicin. |
Naproxen | Naproxen The metabolism of Naproxen can be increased when combined with Rifampicin. |
Trazodone | Trazodone The serum concentration of Trazodone can be decreased when it is combined with Rifampicin. |
Sodium Bicarbonate | Sodium Bicarbonate Sodium bicarbonate can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Phenobarbital | Phenobarbital The metabolism of Phenobarbital can be increased when combined with Rifampicin. |
Methotrexate Injection | Methotrexate Injection The metabolism of Methotrexate can be increased when combined with Rifampicin. |
Primidone | Primidone The metabolism of Rifampicin can be increased when combined with Primidone. |
Methsuximide | Methsuximide The metabolism of Methsuximide can be increased when combined with Rifampicin. |
Chlorpromazine | Chlorpromazine The metabolism of Chlorpromazine can be increased when combined with Rifampicin. |
Diazepam | Diazepam The metabolism of Diazepam can be increased when combined with Rifampicin. |
Oxazepam | Oxazepam The metabolism of Oxazepam can be increased when combined with Rifampicin. |
Flurazepam | Flurazepam The metabolism of Flurazepam can be increased when combined with Rifampicin. |
Lorazepam | Lorazepam The metabolism of Rifampicin can be increased when combined with Lorazepam. |
Carmustine | Carmustine The metabolism of Carmustine can be increased when combined with Rifampicin. |
Tetracycline | Tetracycline The excretion of Tetracycline can be decreased when combined with Rifampicin. |
Prochlorperazine | Prochlorperazine The metabolism of Rifampicin can be increased when combined with Prochlorperazine. |
Thioridazine | Thioridazine The metabolism of Thioridazine can be increased when combined with Rifampicin. |
Trifluoperazine | Trifluoperazine The metabolism of Trifluoperazine can be increased when combined with Rifampicin. |
Dapsone | Dapsone The metabolism of Dapsone can be increased when combined with Rifampicin. |
Sulfadiazine | Sulfadiazine The metabolism of Sulfadiazine can be increased when combined with Rifampicin. |
Oxycodone | Oxycodone The metabolism of Oxycodone can be increased when combined with Rifampicin. |
Methadone | Methadone The metabolism of Methadone can be increased when combined with Rifampicin. |
Oxybutynin | Oxybutynin The metabolism of Oxybutynin can be increased when combined with Rifampicin. |
Maprotiline | Maprotiline The metabolism of Maprotiline can be increased when combined with Rifampicin. |
Ibuprofen | Ibuprofen The metabolism of Ibuprofen can be increased when combined with Rifampicin. |
Perphenazine | Perphenazine The metabolism of Perphenazine can be increased when combined with Rifampicin. |
Azathioprine | Azathioprine The metabolism of Azathioprine can be increased when combined with Rifampicin. |
Phentermine | Phentermine The metabolism of Rifampicin can be increased when combined with Phentermine. |
Sulfasalazine | Sulfasalazine The excretion of Rifampicin can be decreased when combined with Sulfasalazine. |
Hydrocortisone | Hydrocortisone The metabolism of Hydrocortisone can be increased when combined with Rifampicin. |
Doxorubicin | Doxorubicin The serum concentration of Doxorubicin can be decreased when it is combined with Rifampicin. |
Dactinomycin | Dactinomycin The serum concentration of Dactinomycin can be decreased when it is combined with Rifampicin. |
Carbamazepine | Carbamazepine The metabolism of Rifampicin can be increased when combined with Carbamazepine. |
Clonidine | Clonidine The metabolism of Clonidine can be increased when combined with Rifampicin. |
Cimetidine | Cimetidine Cimetidine can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Warfarin | Warfarin The metabolism of Warfarin can be increased when combined with Rifampicin. |
Clonazepam | Clonazepam The metabolism of Clonazepam can be increased when combined with Rifampicin. |
Loperamide | Loperamide The metabolism of Loperamide can be increased when combined with Rifampicin. |
Daunorubicin | Daunorubicin Rifampicin may decrease the excretion rate of Daunorubicin which could result in a higher serum level. |
Nitrofurantoin | Nitrofurantoin Rifampicin may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level. |
Digoxin | Digoxin The serum concentration of Digoxin can be decreased when it is combined with Rifampicin. |
Chloroquine | Chloroquine The metabolism of Chloroquine can be increased when combined with Rifampicin. |
Quinine | Quinine The metabolism of Quinine can be increased when combined with Rifampicin. |
Ethosuximide | Ethosuximide The metabolism of Ethosuximide can be increased when combined with Rifampicin. |
Triamterene | Triamterene The metabolism of Triamterene can be increased when combined with Rifampicin. |
Lactulose | Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Rifampicin. |
Sulfinpyrazone | Sulfinpyrazone Rifampicin may decrease the excretion rate of Sulfinpyrazone which could result in a higher serum level. |
Isosorbide | Isosorbide The metabolism of Isosorbide can be increased when combined with Rifampicin. |
Clindamycin Injection | Clindamycin Injection The metabolism of Clindamycin can be increased when combined with Rifampicin. |
Amitriptyline | Amitriptyline The metabolism of Amitriptyline can be increased when combined with Rifampicin. |
Imipramine | Imipramine The serum concentration of Imipramine can be decreased when it is combined with Rifampicin. |
Quinidine | Quinidine The metabolism of Quinidine can be increased when combined with Rifampicin. |
Disopyramide | Disopyramide The metabolism of Disopyramide can be increased when combined with Rifampicin. |
Valproic Acid | Valproic Acid The metabolism of Valproic acid can be increased when combined with Rifampicin. |
Tamoxifen | Tamoxifen The serum concentration of Rifampicin can be decreased when it is combined with Tamoxifen. |
Levothyroxine | Levothyroxine The metabolism of Levothyroxine can be increased when combined with Rifampicin. |
Liothyronine | Liothyronine The metabolism of Liothyronine can be increased when combined with Rifampicin. |
Chlorpropamide | Chlorpropamide The serum concentration of Chlorpropamide can be decreased when it is combined with Rifampicin. |
Tolbutamide | Tolbutamide The serum concentration of Tolbutamide can be decreased when it is combined with Rifampicin. |
Tolazamide | Tolazamide The serum concentration of Tolazamide can be decreased when it is combined with Rifampicin. |
Dextromethorphan | Dextromethorphan The metabolism of Dextromethorphan can be increased when combined with Rifampicin. |
Dinoprostone | Dinoprostone The excretion of Dinoprostone can be decreased when combined with Rifampicin. |
Cyclobenzaprine | Cyclobenzaprine The metabolism of Cyclobenzaprine can be increased when combined with Rifampicin. |
Chlorpheniramine | Chlorpheniramine The metabolism of Chlorpheniramine can be increased when combined with Rifampicin. |
Hydrochlorothiazide | Hydrochlorothiazide The excretion of Hydrochlorothiazide can be decreased when combined with Rifampicin. |
Chlorzoxazone | Chlorzoxazone The metabolism of Chlorzoxazone can be increased when combined with Rifampicin. |
Carisoprodol | Carisoprodol The metabolism of Carisoprodol can be increased when combined with Rifampicin. |
Disulfiram | Disulfiram The metabolism of Disulfiram can be increased when combined with Rifampicin. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The serum concentration of Propranolol can be decreased when it is combined with Rifampicin. |
Minoxidil | Minoxidil The metabolism of Minoxidil can be increased when combined with Rifampicin. |
Nortriptyline | Nortriptyline The serum concentration of Nortriptyline can be decreased when it is combined with Rifampicin. |
Spironolactone | Spironolactone Rifampicin may decrease the excretion rate of Spironolactone which could result in a higher serum level. |
Mercaptopurine | Mercaptopurine The excretion of Mercaptopurine can be decreased when combined with Rifampicin. |
Nadolol | Nadolol The metabolism of Nadolol can be increased when combined with Rifampicin. |
Allopurinol | Allopurinol The excretion of Allopurinol can be decreased when combined with Rifampicin. |
Fluorouracil Injection | Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Rifampicin. |
Cefaclor | Cefaclor Rifampicin may decrease the excretion rate of Cefaclor which could result in a higher serum level. |
Cefazolin Injection | Cefazolin Injection The excretion of Cefazolin can be decreased when combined with Rifampicin. |
Cephalexin | Cephalexin The metabolism of Rifampicin can be increased when combined with Cephalexin. |
Dacarbazine | Dacarbazine The metabolism of Dacarbazine can be increased when combined with Rifampicin. |
Nystatin | Nystatin The excretion of Rifampicin can be decreased when combined with Nystatin. |
Ketoconazole | Ketoconazole Rifampicin may decrease the excretion rate of Ketoconazole which could result in a higher serum level. |
Thiotepa Injection | Thiotepa Injection The metabolism of Thiotepa can be increased when combined with Rifampicin. |
Vincristine Injection | Vincristine Injection The serum concentration of Vincristine can be decreased when it is combined with Rifampicin. |
Captopril | Captopril The excretion of Captopril can be decreased when combined with Rifampicin. |
Dipyridamole | Dipyridamole Dipyridamole may decrease the excretion rate of Rifampicin which could result in a higher serum level. |
Vinblastine | Vinblastine The metabolism of Vinblastine can be increased when combined with Rifampicin. |
Metoprolol | Metoprolol The metabolism of Metoprolol can be increased when combined with Rifampicin. |
Hydroxyzine | Hydroxyzine The metabolism of Hydroxyzine can be increased when combined with Rifampicin. |
Thiothixene | Thiothixene The metabolism of Thiothixene can be increased when combined with Rifampicin. |
Alprazolam | Alprazolam The metabolism of Alprazolam can be increased when combined with Rifampicin. |
Triazolam | Triazolam The metabolism of Triazolam can be increased when combined with Rifampicin. |
Diltiazem | Diltiazem The metabolism of Diltiazem can be increased when combined with Rifampicin. |
Nifedipine | Nifedipine The metabolism of Nifedipine can be increased when combined with Rifampicin. |
Timolol | Timolol The metabolism of Timolol can be increased when combined with Rifampicin. |
Verapamil | Verapamil The metabolism of Verapamil can be increased when combined with Rifampicin. |
Atenolol | Atenolol The metabolism of Atenolol can be increased when combined with Rifampicin. |
Pindolol | Pindolol The metabolism of Pindolol can be increased when combined with Rifampicin. |
Piroxicam | Piroxicam The metabolism of Piroxicam can be increased when combined with Rifampicin. |
Bumetanide | Bumetanide The excretion of Bumetanide can be decreased when combined with Rifampicin. |
Etoposide | Etoposide The metabolism of Etoposide can be increased when combined with Rifampicin. |
Glyburide | Glyburide The serum concentration of Glyburide can be decreased when it is combined with Rifampicin. |
Glipizide | Glipizide The serum concentration of Glipizide can be decreased when it is combined with Rifampicin. |
Pentoxifylline | Pentoxifylline The metabolism of Pentoxifylline can be increased when combined with Rifampicin. |
Pentamidine Injection | Pentamidine Injection The metabolism of Pentamidine can be increased when combined with Rifampicin. |
Labetalol | Labetalol The metabolism of Labetalol can be increased when combined with Rifampicin. |
Gemfibrozil | Gemfibrozil The metabolism of Rifampicin can be increased when combined with Gemfibrozil. |
Guanabenz | Guanabenz The metabolism of Guanabenz can be increased when combined with Rifampicin. |
Dipivefrin Ophthalmic | Dipivefrin Ophthalmic The excretion of Adefovir dipivoxil can be decreased when combined with Rifampicin. |
Ketoprofen | Ketoprofen The metabolism of Ketoprofen can be increased when combined with Rifampicin. |
Pimozide | Pimozide The metabolism of Pimozide can be increased when combined with Rifampicin. |
Enalapril | Enalapril The excretion of Enalapril can be decreased when combined with Rifampicin. |
Flurbiprofen | Flurbiprofen The metabolism of Flurbiprofen can be increased when combined with Rifampicin. |
Amiodarone | Amiodarone The serum concentration of Amiodarone can be decreased when it is combined with Rifampicin. |
Buspirone | Buspirone The serum concentration of Buspirone can be decreased when it is combined with Rifampicin. |
Lovastatin | Lovastatin The metabolism of Lovastatin can be increased when combined with Rifampicin. |
Diclofenac | Diclofenac The metabolism of Diclofenac can be increased when combined with Rifampicin. |
Fluoxetine | Fluoxetine The metabolism of Fluoxetine can be increased when combined with Rifampicin. |
Clozapine | Clozapine The metabolism of Clozapine can be increased when combined with Rifampicin. |
Ofloxacin | Ofloxacin Rifampicin may decrease the excretion rate of Ofloxacin which could result in a higher serum level. |
Didanosine | Didanosine The excretion of Didanosine can be decreased when combined with Rifampicin. |
Clarithromycin | Clarithromycin The metabolism of Clarithromycin can be increased when combined with Rifampicin. |
Etodolac | Etodolac The metabolism of Etodolac can be increased when combined with Rifampicin. |
Felodipine | Felodipine The metabolism of Felodipine can be increased when combined with Rifampicin. |
Nabumetone | Nabumetone The metabolism of Nabumetone can be increased when combined with Rifampicin. |
Pravastatin | Pravastatin Rifampicin may decrease the excretion rate of Pravastatin which could result in a higher serum level. |
Quinapril | Quinapril The excretion of Quinapril can be decreased when combined with Rifampicin. |
Simvastatin | Simvastatin The metabolism of Simvastatin can be increased when combined with Rifampicin. |
Teniposide Injection | Teniposide Injection The metabolism of Teniposide can be increased when combined with Rifampicin. |
Sotalol | Sotalol The metabolism of Sotalol can be increased when combined with Rifampicin. |
Bisoprolol | Bisoprolol The metabolism of Bisoprolol can be increased when combined with Rifampicin. |
Zolpidem | Zolpidem The therapeutic efficacy of Zolpidem can be decreased when used in combination with Rifampicin. |
Doxazosin | Doxazosin The metabolism of Doxazosin can be increased when combined with Rifampicin. |
Isradipine | Isradipine Rifampicin may decrease the excretion rate of Isradipine which could result in a higher serum level. |
Omeprazole | Omeprazole The serum concentration of Omeprazole can be decreased when it is combined with Rifampicin. |
Cisapride | Cisapride The metabolism of Cisapride can be increased when combined with Rifampicin. |
Fluvastatin | Fluvastatin The metabolism of Fluvastatin can be increased when combined with Rifampicin. |
Nizatidine | Nizatidine Nizatidine can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Stavudine | Stavudine The excretion of Stavudine can be decreased when combined with Rifampicin. |
Famciclovir | Famciclovir The metabolism of Rifampicin can be increased when combined with Famciclovir. |
Fluvoxamine | Fluvoxamine The metabolism of Fluvoxamine can be increased when combined with Rifampicin. |
Nefazodone | Nefazodone Nefazodone may decrease the excretion rate of Rifampicin which could result in a higher serum level. |
Lamotrigine | Lamotrigine The serum concentration of Lamotrigine can be decreased when it is combined with Rifampicin. |
Losartan | Losartan The serum concentration of Losartan can be decreased when it is combined with Rifampicin. |
Valacyclovir | Valacyclovir The excretion of Valaciclovir can be decreased when combined with Rifampicin. |
Tramadol | Tramadol The metabolism of Tramadol can be increased when combined with Rifampicin. |
Vinorelbine Injection | Vinorelbine Injection The metabolism of Vinorelbine can be increased when combined with Rifampicin. |
Lansoprazole | Lansoprazole Lansoprazole can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Alprostadil Urogenital | Alprostadil Urogenital The excretion of Alprostadil can be decreased when combined with Rifampicin. |
Ifosfamide Injection | Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Rifampicin. |
Nicardipine | Nicardipine The metabolism of Nicardipine can be increased when combined with Rifampicin. |
Ticlopidine | Ticlopidine The metabolism of Rifampicin can be increased when combined with Ticlopidine. |
Saquinavir | Saquinavir The serum concentration of Saquinavir can be decreased when it is combined with Rifampicin. |
Nisoldipine | Nisoldipine The metabolism of Nisoldipine can be increased when combined with Rifampicin. |
Lamivudine | Lamivudine The excretion of Lamivudine can be decreased when combined with Rifampicin. |
Riluzole | Riluzole The metabolism of Riluzole can be increased when combined with Rifampicin. |
Glimepiride | Glimepiride The serum concentration of Glimepiride can be decreased when it is combined with Rifampicin. |
Anastrozole | Anastrozole The metabolism of Anastrozole can be increased when combined with Rifampicin. |
Gemcitabine Injection | Gemcitabine Injection The serum concentration of Gemcitabine can be decreased when it is combined with Rifampicin. |
Indinavir | Indinavir The metabolism of Indinavir can be increased when combined with Rifampicin. |
Ritonavir | Ritonavir The serum concentration of Ritonavir can be decreased when it is combined with Rifampicin. |
Docetaxel Injection | Docetaxel Injection The metabolism of Docetaxel can be increased when combined with Rifampicin. |
Cidofovir Injection | Cidofovir Injection The excretion of Cidofovir can be decreased when combined with Rifampicin. |
Clomipramine | Clomipramine The metabolism of Clomipramine can be increased when combined with Rifampicin. |
Zafirlukast | Zafirlukast The metabolism of Zafirlukast can be increased when combined with Rifampicin. |
Mirtazapine | Mirtazapine The metabolism of Mirtazapine can be increased when combined with Rifampicin. |
Zileuton | Zileuton The metabolism of Zileuton can be increased when combined with Rifampicin. |
Valsartan | Valsartan The excretion of Valsartan can be decreased when combined with Rifampicin. |
Nelfinavir | Nelfinavir Nelfinavir may decrease the excretion rate of Rifampicin which could result in a higher serum level. |
Fexofenadine | Fexofenadine The serum concentration of Fexofenadine can be increased when it is combined with Rifampicin. |
Azithromycin | Azithromycin The metabolism of Azithromycin can be increased when combined with Rifampicin. |
Loratadine | Loratadine Rifampicin may decrease the excretion rate of Loratadine which could result in a higher serum level. |
Carvedilol | Carvedilol The metabolism of Carvedilol can be increased when combined with Rifampicin. |
Flutamide | Flutamide The metabolism of Flutamide can be increased when combined with Rifampicin. |
Selegiline | Selegiline The metabolism of Selegiline can be increased when combined with Rifampicin. |
Bicalutamide | Bicalutamide The metabolism of Bicalutamide can be increased when combined with Rifampicin. |
Sertraline | Sertraline The metabolism of Sertraline can be increased when combined with Rifampicin. |
Propafenone | Propafenone The metabolism of Propafenone can be increased when combined with Rifampicin. |
Letrozole | Letrozole The metabolism of Letrozole can be increased when combined with Rifampicin. |
Raloxifene | Raloxifene The metabolism of Raloxifene can be increased when combined with Rifampicin. |
Irbesartan | Irbesartan The metabolism of Irbesartan can be increased when combined with Rifampicin. |
Ropinirole | Ropinirole The metabolism of Ropinirole can be increased when combined with Rifampicin. |
Finasteride | Finasteride The metabolism of Finasteride can be increased when combined with Rifampicin. |
Quetiapine | Quetiapine The metabolism of Quetiapine can be increased when combined with Rifampicin. |
Paroxetine | Paroxetine The metabolism of Paroxetine can be increased when combined with Rifampicin. |
Citalopram | Citalopram The serum concentration of Citalopram can be decreased when it is combined with Rifampicin. |
Efavirenz | Efavirenz The metabolism of Efavirenz can be increased when combined with Rifampicin. |
Abacavir | Abacavir The metabolism of Abacavir can be increased when combined with Rifampicin. |
Sildenafil | Sildenafil The metabolism of Sildenafil can be increased when combined with Rifampicin. |
Pioglitazone | Pioglitazone The metabolism of Pioglitazone can be increased when combined with Rifampicin. |
Celecoxib | Celecoxib The metabolism of Celecoxib can be increased when combined with Rifampicin. |
Rosiglitazone | Rosiglitazone The metabolism of Rosiglitazone can be increased when combined with Rifampicin. |
Oseltamivir | Oseltamivir The excretion of Oseltamivir can be decreased when combined with Rifampicin. |
Aluminum Hydroxide | Aluminum Hydroxide Aluminum hydroxide can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Nateglinide | Nateglinide The metabolism of Nateglinide can be increased when combined with Rifampicin. |
Rabeprazole | Rabeprazole Rabeprazole can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Terbinafine | Terbinafine The metabolism of Terbinafine can be increased when combined with Rifampicin. |
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists