Alfuzosin
Alfuzosin is an alpha blocker used to treat the signs and symptoms of benign prostatic hyperplasia (BPH, or enlarged prostate) in men.
🧬 Where this information comes from Click to expand
The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 18 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →
Alfuzosin is a once-daily tablet that eases the urinary symptoms of benign prostatic hyperplasia. Take it with the same meal each day and swallow it whole. Stand up slowly, and check with your pharmacist or doctor before adding other medicines, especially antifungals, blood pressure medicines or erectile dysfunction drugs.
📖 Alfuzosin: Patient Information Guide
A plain-language walkthrough of Alfuzosin — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.
What Alfuzosin is used for
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Alfuzosin is used for one condition across all supported products.
- Signs and symptoms of benign prostatic hyperplasia (BPH, or enlarged prostate), for Alfuzosin Hydrochloride tablets and extended-release tablets, and Uroxatral.
- Not for high blood pressure.
- Not for children.
How Alfuzosin works
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Alfuzosin is an alpha-1 blocker. It blocks alpha-1 receptors found in the prostate, bladder base, bladder neck, prostatic capsule and urethra. This lets the smooth muscle in the bladder neck and prostate relax. The result is better urine flow and fewer BPH symptoms.
How Alfuzosin is taken (dosage)
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Alfuzosin is taken by mouth once a day. Take it with food, and with the same meal each day, because absorption is about 50% lower when fasting. Swallow tablets whole. Do not chew or crush them.
Follow your prescriber’s directions and your pharmacy label.
Alfuzosin side effects in detail
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Most side effects are mild. The most common ones were:
- Dizziness
- Upper respiratory tract infection
- Headache
- Fatigue
- Abdominal pain, indigestion, constipation, nausea
- Impotence
Fainting, allergic reactions, liver problems, a long-lasting erection or chest pain need prompt medical attention.
Alfuzosin warnings and precautions
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- Low blood pressure and fainting: Stand up slowly. Take extra care if you take blood pressure medicines or nitrates.
- Liver disease: Alfuzosin must not be used with moderate or severe liver impairment.
- Strong CYP3A4 inhibitors: These raise alfuzosin levels and must not be combined with it.
- Severe kidney impairment: Use with caution.
- Cataract surgery: Intraoperative Floppy Iris Syndrome has been reported.
- Heart effects: Chest pain and angina in people with coronary artery disease, as well as atrial fibrillation, have been reported after approval.
Alfuzosin interactions: what it interacts with
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Some medicines can raise alfuzosin levels or add to its blood pressure effects.
- Ketoconazole, itraconazole, ritonavir: raise alfuzosin blood levels. Do not combine.
- Other alpha blockers: interactions are expected, so do not combine.
- Blood pressure medicines and nitrates: higher risk of low blood pressure and fainting.
- PDE5 inhibitors: both lower blood pressure, so symptomatic hypotension is possible.
This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.
Before taking Alfuzosin
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- Do not take it with moderate or severe liver impairment.
- Do not take it if you are allergic to alfuzosin or any of its ingredients.
- Tell your doctor if you have low blood pressure or severe kidney impairment.
- It is not indicated for women, including during pregnancy or breastfeeding.
- It is not indicated for children. It did not work in a trial in patients ages 2 to 16.
- Older adults (75 and over) had about 35% higher trough levels than those under 65.
Alfuzosin overdose: if you take too much
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Too much alfuzosin can cause low blood pressure. Treatment focuses on supporting the heart and circulation, such as lying flat, and sometimes IV fluids or medicines to raise blood pressure. Dialysis may not help because alfuzosin binds strongly to proteins in the blood.
Pharmacodynamics: what Alfuzosin does in the body
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Alfuzosin is selective for alpha receptors in the lower urinary tract. Blocking them relaxes smooth muscle in the bladder neck and prostate, which improves urine flow. In heart rhythm studies, higher doses showed a larger effect on the QT interval (a heart rhythm measure). Even so, the effect was smaller than the comparison drug, and the clinical impact is unknown.
Pharmacokinetics: how your body processes Alfuzosin
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With food, about 49% of the extended-release tablet is absorbed, and blood levels peak around 8 hours after dosing. Absorption is about 50% lower when fasting. The liver breaks alfuzosin down extensively, mainly through CYP3A4, and the metabolites are not active. It leaves the body mostly in feces, and some in urine, with a half-life of about 10 hours.
How to store Alfuzosin
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Store at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F) . Dispense in a tight, light-resistant container as described in the USP. Protect from light and moisture.
📄 Written from Alfuzosin’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →
Supplements & herbs that interact with Alfuzosin
139 supplements and herbal products have documented interactions with Alfuzosin in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.
- Major · 3
- Moderate · 95
- Minor · 41
Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.
🩺 Alfuzosin: pharmacist answers to common questions
Quick, plain-English answers to the questions patients ask most about Alfuzosin — the kind of thing our pharmacy team would talk through with you at the counter.
What is alfuzosin for?
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How should I take it?
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What side effects should I expect?
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When should I call my doctor?
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What medicines should I avoid with it?
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I’m having cataract surgery. Does it matter?
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Is Alfuzosin available over the counter?
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When was Alfuzosin first available?
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Who makes Alfuzosin?
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💬 Answers drafted from Alfuzosin’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →
🧰 More about Alfuzosin on HelloPharmacist
💊 Alfuzosin forms and strengths (how it comes)
Alfuzosin is available in 2 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.
Extended-release tablet
How this form is used
- Alfuzosin Hydrochloride extended-release tablets are used for signs and symptoms of benign prostatic hyperplasia.
- Uroxatral is used for signs and symptoms of benign prostatic hyperplasia.
- Alfuzosin Hydrochloride extended-release tablets are taken once daily with food and with the same meal each day.
- Uroxatral is taken once daily with food and with the same meal each day.
- Uroxatral and Alfuzosin Hydrochloride extended-release tablets should not be chewed or crushed.
Tablet
How this form is used
- Alfuzosin Hydrochloride tablets are used for signs and symptoms of benign prostatic hyperplasia.
- Alfuzosin Hydrochloride tablets are taken once daily with food and with the same meal each day.
- Alfuzosin Hydrochloride tablets should not be chewed or crushed.
📊 Alfuzosin on the U.S. market: products, makers and brands
How Alfuzosin appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.
FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
Also listed with the FDA, not a patient dose form: Powder (8) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.
Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
📈 How widely Alfuzosin is used (Medicaid data)
A general measure of how commonly Alfuzosin is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.
Think of this as a proxy for how widely Alfuzosin is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.
How commonly is Alfuzosin prescribed? Of the 1,599 medications we measure, Alfuzosin ranks #547 by Medicaid prescriptions — more than 66% of them.
Utilization by Alfuzosin product
Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.
24 HR alfuzosin hydrochloride 10 MG Extended Release Oral Tablet
Summed across the 6 of 77 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 861132
Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.
Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Alfuzosin, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 6 of 77 listed Alfuzosin NDCs with Medicaid activity.
🔍 Compare Alfuzosin products
A representative set of FDA-listed product records for Alfuzosin — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)
| Strength | Route | Manufacturer / Labeler | Category ⓘ | Details |
|---|---|---|---|---|
| 💊Extended-release tablet | ||||
| 10 mg | Oral | Advanz Pharma (US) Corp. | NDA | View NDC → |
| 10 mg | Oral | Aphena Pharma Solutions - Tennessee, LLC | ANDA | View NDC → |
| 10 mg | Oral | Apotex Corp. × 3 listings | ANDA | View NDC → |
| 10 mg | — | Aurobindo Pharma Limited | DRUG FOR FURTHER PROCESSING | View NDC → |
| 10 mg | Oral | Aurobindo Pharma Limited × 4 listings | ANDA | View NDC → |
| 10 mg | Oral | Bryant Ranch Prepack × 15 listings | ANDA | View NDC → |
| 10 mg | Oral | Concordia Pharmaceuticals Inc. | NDA | View NDC → |
| 10 mg | Oral | Denton Pharma, Inc. DBA Northwind Pharmaceuticals | ANDA | Find on DailyMed ↗ |
| 10 mg | Oral | DirectRX | ANDA | Find on DailyMed ↗ |
| 10 mg | Oral | Exelan Pharmaceuticals Inc. × 3 listings | ANDA | View NDC → |
| 10 mg | Oral | Golden State Medical Supply, Inc. | ANDA | View NDC → |
| 10 mg | Oral | Northwind Health Company, LLC × 3 listings | ANDA | View NDC → |
| 10 mg | Oral | Northwind Pharmaceuticals, LLC × 3 listings | ANDA | View NDC → |
| 10 mg | Oral | Rising Health, LLC | ANDA | View NDC → |
| 10 mg | Oral | Rising Pharma Holdings, Inc. × 2 listings | ANDA | View NDC → |
| 10 mg | Oral | Sun Pharmaceutical Industries, Inc. × 2 listings | ANDA | View NDC → |
| 10 mg | Oral | Unichem Pharmaceuticals (USA), Inc. | ANDA | View NDC → |
| 💊Tablet | ||||
| 10 mg | Oral | Cipla USA Inc. | ANDA | View NDC → |
| 10 mg | Oral | Denton Pharma, Inc. DBA Northwind Pharmaceuticals | ANDA | View NDC → |
| 10 mg | Oral | Wockhardt USA LLC. | ANDA | View NDC → |
| 💊Bulk drug substance | ||||
| 1 kg/kg | — | Alivus Life Sciences Limited | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Apotex Inc. | BULK INGREDIENT | View NDC → |
| 50 kg/50 kg | — | Aurobindo Pharma Limited | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | CZECH-GEN, a.s. | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Farmak, a,s | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Hetero Drugs Limited | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | MSN Laboratories Private Limited | BULK INGREDIENT | View NDC → |
| 1 kg/kg | — | Unichem Laboratories Limited, India | BULK INGREDIENT | View NDC → |
Showing 55 of 55 products — FDA National Drug Code Directory. See every product, package size and price: browse all 55 Alfuzosin NDCs →
📈 Alfuzosin side effects reported to the FDA (FAERS)
After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Alfuzosin — a signal of what to watch for, not proof the drug caused it.
Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Alfuzosin in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.
🏛️ Alfuzosin FDA approval history
How Alfuzosin went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.
Source: Drugs@FDA.
🚨 Alfuzosin recall history
A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.
Source: openFDA drug enforcement (recall) reports.
RxNorm Concept Web — From Ingredient to Every Form and Strength
This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.
RxCUI 17300 2 dose forms · 2 strengths
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Dose form (SCDF) Extended Release Oral Tablet RxCUI 370798In current FDA listingsClinical drug / strength (SCD) 24 HR alfuzosin hydrochloride 10 MGRxCUI 861132 -
Dose form (SCDF) Oral Tablet RxCUI 370797In current FDA listingsClinical drug / strength (SCD) hydrochloride 2.5 MGRxCUI 1088455
Look up RxCUI 17300 in the RxCUI Atlas →
RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.
📦 Alfuzosin supply and shortage status
Whether Alfuzosin is in short supply in the U.S. right now, plus any shortage history the FDA has on record. A shortage usually reflects a manufacturing or demand issue — not a safety problem with the drug.
Source: openFDA, from the FDA Drug Shortages database.
🏷️ Alfuzosin brand names
🏭 Who makes Alfuzosin: manufacturers and labelers
…and 1 more on the FDA NDC directory.
Alfuzosin drug class (RxNorm)
Alfuzosin belongs to the alpha-Adrenergic Blocker class.
Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.
🔬 Sources for this Alfuzosin page
Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.
How we combine label and product data
HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 18 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.
For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Concordia Pharmaceuticals Inc. is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.
This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.