Prazosin
Prazosin is an alpha-blocker-type blood pressure medicine taken by mouth as a capsule to treat high blood pressure (hypertension), alone or with other blood pressure drugs.
🧬 Where this information comes from Click to expand
The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 77 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →
Prazosin (Minipress) is an older alpha-blocker for high blood pressure that relaxes small blood vessels, lowering the risk of stroke and heart attack; on the market since the mid-1970s and available generically, it is now usually an add-on rather than a first choice. Most people tolerate it reasonably well once settled on a dose, though dizziness, headache, drowsiness and low energy are the side effects people notice most. The thing to watch for is fainting from a sudden drop in blood pressure, most often within 30 to 90 minutes of the first dose, after a dose increase or when another blood pressure drug is added.
Clinical pearls
- Take the very first dose at bedtime and get up slowly at night, since the first-dose drop can cause fainting.
- Tell your eye surgeon before cataract surgery, because prazosin can cause floppy iris syndrome, a pupil problem during the operation.
- Erectile dysfunction medicines (PDE-5 inhibitors) add to the blood pressure drop, so they should be started at the lowest dose.
- Rarely it causes an erection lasting over 4 hours, which needs emergency care to prevent permanent damage.
Patient information guide A plain-language walkthrough of Prazosin, written from its FDA label.
What Prazosin is used for
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Prazosin is approved for one main use, based on the oral capsule products:
- High blood pressure (hypertension): Prazosin, Prazosin HCL and Prazosin Hydrochloride capsules lower blood pressure.
- They can be used alone or combined with other blood pressure medicines such as diuretics or beta-blockers.
- Lowering blood pressure reduces the risk of strokes and heart attacks.
How Prazosin works
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Prazosin lowers total peripheral resistance, meaning it relaxes and widens small arteries so blood flows more easily. It is thought to work partly by blocking alpha-adrenoceptors on blood vessels. The exact mechanism is not known.
Unlike conventional alpha-blockers, it usually does not cause a reflex fast heartbeat, and tolerance has not been seen with long-term use.
Prazosin dosage
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Prazosin capsules are taken by mouth, usually two or three times a day at first. Some people can later do well on twice daily. The dose is raised slowly based on your blood pressure.
- Treatment always begins with the lowest-strength capsule.
- If another blood pressure drug is added, the prazosin dose may be lowered and adjusted again.
- Follow your prescriber and pharmacy label for timing and amounts.
Dosing details from the FDA-approved label
From the Prazosin prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.
- Initial dose
- 1 mg two or three times a day
- Maintenance dose
- Dosage may be slowly increased to a total daily dose of 20 mg given in divided doses
- The therapeutic dosages most commonly employed have ranged from 6 mg to 15 mg daily given in divided doses
- After initial titration some patients can be maintained adequately on a twice daily dosage regimen
- Maximum: Doses higher than 20 mg usually do not increase efficacy, however a few patients may benefit from further increases up to a daily dose of 40 mg given in divided doses.
- Use with a diuretic or other antihypertensive agent
- Reduce the prazosin dose to 1 mg or 2 mg three times a day and then carry out retitration
- Use with a PDE-5 inhibitor
- PDE-5 inhibitor therapy should be initiated at the lowest dose in patients taking prazosin
- Concomitant use can result in additive blood pressure lowering effects and symptomatic hypotension
Read the label’s full dosing text
DOSAGE AND ADMINISTRATION The dose of prazosin hydrochloride capsules should be adjusted according to the patient’s individual blood pressure response. The following is a guide to its administration: Initial Dose: 1 mg two or three times a day (see WARNINGS ). Maintenance Dose: Dosage may be slowly increased to a total daily dose of 20 mg given in divided doses. The therapeutic dosages most commonly employed have ranged from 6 mg to 15 mg daily given in divided doses. Doses higher than 20 mg usually do not increase efficacy, however a few patients may benefit from further increases up to a daily dose of 40 mg given in divided doses. After initial titration some patients can be maintained adequately on a twice daily dosage regimen. Use With Other Drugs: When adding a diuretic or other antihypertensive agent, the dose of prazosin hydrochloride capsules should be reduced to 1 mg or 2 mg three times a day and retitration then carried out. Concomitant administration of prazosin hydrochloride capsules with a PDE-5 inhibitor can result in additive blood pressure lowering effects and symptomatic hypotension; therefore, PDE-5 inhibitor therapy should be initiated at the lowest dose in patients taking prazosin hydrochloride capsules.
Read the full Dosage and Administration section on DailyMed →
Prazosin side effects
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Many side effects ease with continued use. The most common are:
Common side effects
- Dizziness
- Headache
- Drowsiness
- Lack of energy
- Weakness
- Palpitations (feeling your heartbeat)
- Nausea
When to get medical help
- Fainting (sudden loss of consciousness): call your doctor, especially if it happens after your first dose or a dose increase.
- An erection lasting longer than 4 hours: get immediate medical help to avoid permanent damage.
- Signs of an allergic reaction such as hives or rash: contact your doctor right away.
- Chest pain (angina), very slow heartbeat or severe low blood pressure: seek medical help.
- Hallucinations or worsening depression: tell your doctor.
Prazosin warnings and precautions
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- Fainting: can occur suddenly, most often within 30 to 90 minutes of the first dose or after a quick dose increase. If it happens, lie down.
- Dizziness and lightheadedness: avoid situations where a fall could cause injury when starting.
- Priapism: a prolonged erection over 4 hours needs immediate care; delay can cause permanent loss of potency.
- Eye surgery: alpha-1 blockers can cause Intraoperative Floppy Iris Syndrome during cataract surgery.
- Narcolepsy: worsening has been reported, though a cause is uncertain.
Prazosin interactions
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Other medicines that lower blood pressure can add to prazosin’s effect.
- Diuretics and other blood pressure drugs: additive blood pressure lowering, so doses may be adjusted.
- Beta-blockers such as propranolol: may cause low blood pressure.
- PDE-5 inhibitors: can cause symptomatic low blood pressure; they should be started at the lowest dose.
- Pheochromocytoma screening tests: prazosin may cause false positives.
Interactions listed in the FDA-approved label
From the Prazosin prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.
- Diuretic or other antihypertensive agent: Addition to prazosin has been shown to cause an additive hypotensive effect. Reduce the prazosin dose to 1 to 2 mg three times a day, introduce additional antihypertensive drugs cautiously, and then retitrate prazosin based on clinical response.
- Phosphodiesterase-5 (PDE-5) inhibitors: Concomitant administration can result in additive blood pressure lowering effects and symptomatic hypotension. PDE-5 inhibitor therapy should be initiated at the lowest dose in patients taking prazosin (see Dosage and Administration).
- Cardiac glycosides (digitalis, digoxin): Administered without any adverse drug interaction in limited clinical experience to date.
- Hypoglycemics (insulin, chlorpropamide, phenformin, tolazamide, tolbutamide): Administered without any adverse drug interaction in limited clinical experience to date.
- Tranquilizers and sedatives (chlordiazepoxide, diazepam, phenobarbital): Administered without any adverse drug interaction in limited clinical experience to date.
- Antigout drugs (allopurinol, colchicine, probenecid): Administered without any adverse drug interaction in limited clinical experience to date.
- Antiarrhythmics (procainamide, propranolol, quinidine): Administered without any adverse drug interaction in limited clinical experience to date. For propranolol, see WARNINGS.
- Analgesics, antipyretics and anti-inflammatories (propoxyphene, aspirin, indomethacin, phenylbutazone): Administered without any adverse drug interaction in limited clinical experience to date.
- Screening tests for pheochromocytoma (urinary VMA and norepinephrine metabolite): In five patients given 12 to 24 mg of prazosin per day for 10 to 14 days, urinary metabolite of norepinephrine increased an average of 42% and urinary VMA an average of 17%, so false positive results may occur. If an elevated VMA is found, prazosin should be discontinued and the patient retested after a month.
Read the label’s full interactions text
Interactions Drug Interactions Prazosin hydrochloride capsules have been administered without any adverse drug interaction in limited clinical experience to date with the following: (1) cardiac glycosides‒digitalis and digoxin; (2) hypoglycemics‒insulin, chlorpropamide, phenformin, tolazamide, and tolbutamide; (3) tranquilizers and sedatives‒chlordiazepoxide, diazepam, and phenobarbital; (4) antigout‒allopurinol, colchicine, and probenecid; (5) antiarrhythmics‒procainamide, propranolol (see WARNINGS however), and quinidine; and (6) analgesics, antipyretics and anti-inflammatories-propoxyphene, aspirin, indomethacin, and phenylbutazone. Addition of a diuretic or other antihypertensive agent to prazosin hydrochloride capsules have been shown to cause an additive hypotensive effect. This effect can be minimized by reducing the prazosin hydrochloride capsules dose to 1 to 2 mg three times a day, by introducing additional antihypertensive drugs cautiously, and then by retitrating prazosin hydrochloride capsules based on clinical response. Concomitant administration of prazosin hydrochloride capsules with a phosphodiesterase-5 (PDE-5) inhibitor can result in additive blood pressure lowering effects and symptomatic hypotension (see DOSAGE AND ADMINISTRATION ). Drug/Laboratory Test Interactions In a study on five patients given from 12 to 24 mg of prazosin per day for 10 to 14 days, there was an average increase of 42% in the urinary metabolite of norepinephrine and an average increase in urinary VMA of 17%. Therefore, false positive results may occur in screening tests for pheochromocytoma in patients who are being treated with prazosin. If an elevated VMA is found, prazosin should be discontinued and the patient retested after a month.
Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →
Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.
Before taking Prazosin
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- Do not take it if you are allergic to prazosin, quinazolines or any inactive ingredient.
- Tell your doctor about all blood pressure medicines and PDE-5 inhibitors you use.
- Tell your eye surgeon you take prazosin before cataract surgery.
- Mention narcolepsy if you have it.
Prazosin overdose
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In one report, a two-year-old who swallowed at least 50 mg had profound drowsiness and depressed reflexes but recovered fully. If overdose causes low blood pressure, treatment focuses on supporting the heart and circulation, such as lying flat, fluids and, if needed, medicines to raise blood pressure. Prazosin is not removed by dialysis.
What Prazosin does in the body
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Prazosin lowers blood pressure in both lying and standing positions, with the strongest effect on diastolic pressure (the bottom number). It does not significantly change cardiac output, heart rate, kidney blood flow or kidney filtration. It has not raised plasma renin activity, and lipid levels generally showed no adverse changes.
How your body processes Prazosin
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After a dose by mouth, blood levels peak at about three hours, and the half-life is two to three hours. Prazosin is highly bound to proteins in the blood. It is extensively metabolized and excreted mainly through bile and feces.
How to store Prazosin
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Store at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F) . Dispense in a tight, light-resistant containers (USP).
Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →
Supplements & herbs that interact with Prazosin
137 supplements and herbal products have documented interactions with Prazosin in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.
- Major · 4
- Moderate · 112
- Minor · 21
Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.
Nutrient depletion considerations
Prazosin has been associated with lower levels of 1 nutrient in the clinical literature. This does not mean a deficiency will occur — it means these may be worth discussing with your pharmacist or healthcare provider, especially with long-term use.
Educational information from a licensed clinical database (Natural Medicines) — not medical advice. Do not start or stop medications or supplements without professional guidance.
Prazosin: pharmacist answers to common questions
Quick, plain-English answers to the questions patients ask most about Prazosin — the kind of thing our pharmacy team would talk through with you at the counter.
What is prazosin for?
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How should I take it?
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Why am I dizzy after my first dose?
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What side effects are normal?
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When should I get urgent help?
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Can I take it with other medicines?
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Is Prazosin available over the counter?
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When was Prazosin first available?
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Who makes Prazosin?
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Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →
More about Prazosin on HelloPharmacist
Prazosin forms and strengths (how it comes)
Prazosin is available in 2 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.
Capsule
How this form is used
- Prazosin, Prazosin HCL and Prazosin Hydrochloride capsules are used to treat high blood pressure.
- Prazosin, Prazosin HCL and Prazosin Hydrochloride capsules can be used alone or with diuretics or beta-blockers.
- Prazosin, Prazosin HCL and Prazosin Hydrochloride capsules are taken by mouth, usually two or three times a day to start.
- Prazosin, Prazosin HCL and Prazosin Hydrochloride capsules are adjusted to your blood pressure response.
- Prazosin, Prazosin HCL and Prazosin Hydrochloride capsules should always be started at the lowest capsule strength.
Tablet
Prazosin on the U.S. market: products, makers and brands
How Prazosin appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.
33 companies list 111 Prazosin product records with the FDA, mostly as capsule, tablet; the earliest marketing or approval year on record is 1976. Brand names on the directory include Minipress, Minipress XL; the rest are generics.
FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
Also listed with the FDA, not a patient dose form: Powder (9) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.
Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
How widely Prazosin is used (Medicaid data)
A general measure of how commonly Prazosin is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.
Think of this as a proxy for how widely Prazosin is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.
How commonly is Prazosin prescribed? Of the 1,601 medications we measure, Prazosin ranks #111 by Medicaid prescriptions — more than 93% of them.
Utilization by Prazosin product
Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.
prazosin 1 MG Oral Capsule Most dispensed
Summed across the 20 of 126 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 312593
prazosin 2 MG Oral Capsule
Summed across the 18 of 114 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 312594
prazosin 5 MG Oral Capsule
Summed across the 18 of 98 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 198141
Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.
Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Prazosin, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 56 of 338 listed Prazosin NDCs with Medicaid activity.
Compare Prazosin products
A representative set of FDA-listed product records for Prazosin — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)
| Strength | Route | Manufacturer / Labeler | Category ⓘ | Details |
|---|---|---|---|---|
| 💊Capsule | ||||
| 1 mg | Oral | A-S Medication Solutions × 2 listings | ANDA | View NDC → |
| 1 mg | Oral | Alembic Pharmaceuticals Inc. | ANDA | View NDC → |
| 2 mg | Oral | Alembic Pharmaceuticals Inc. | ANDA | View NDC → |
| 5 mg | Oral | Alembic Pharmaceuticals Inc. | ANDA | View NDC → |
| 1 mg | Oral | Alembic Pharmaceuticals Limited | ANDA | View NDC → |
| 2 mg | Oral | Alembic Pharmaceuticals Limited | ANDA | View NDC → |
| 5 mg | Oral | Alembic Pharmaceuticals Limited | ANDA | View NDC → |
| 1 mg | Oral | American Health Packaging | ANDA | View NDC → |
| 2 mg | Oral | American Health Packaging | ANDA | View NDC → |
| 5 mg | Oral | American Health Packaging | ANDA | View NDC → |
| 1 mg | Oral | ANI Pharmaceuticals, Inc. | ANDA | View NDC → |
| 2 mg | Oral | ANI Pharmaceuticals, Inc. | ANDA | View NDC → |
| 5 mg | Oral | ANI Pharmaceuticals, Inc. | ANDA | View NDC → |
| 1 mg | Oral | Aphena Pharma Solutions - Tennessee, LLC | ANDA | View NDC → |
| 2 mg | Oral | Aphena Pharma Solutions - Tennessee, LLC × 3 listings | ANDA | View NDC → |
| 5 mg | Oral | Aphena Pharma Solutions - Tennessee, LLC | ANDA | View NDC → |
| 1 mg | Oral | Asclemed Usa Inc. | ANDA | View NDC → |
| 2 mg | Oral | Asclemed Usa Inc. | ANDA | View NDC → |
| 5 mg | Oral | Asclemed Usa Inc. | ANDA | View NDC → |
| 1 mg | Oral | Aurobindo Pharma Limited | ANDA | View NDC → |
| 2 mg | Oral | Aurobindo Pharma Limited | ANDA | View NDC → |
| 5 mg | Oral | Aurobindo Pharma Limited | ANDA | View NDC → |
| 1 mg | Oral | Biocon Pharma Inc. | ANDA | View NDC → |
| 2 mg | Oral | Biocon Pharma Inc. | ANDA | View NDC → |
| 5 mg | Oral | Biocon Pharma Inc. | ANDA | View NDC → |
| 1 mg | Oral | Bryant Ranch Prepack × 5 listings | ANDA | View NDC → |
| 2 mg | Oral | Bryant Ranch Prepack × 2 listings | ANDA | View NDC → |
| 5 mg | Oral | Bryant Ranch Prepack | ANDA | View NDC → |
| 1 mg | Oral | Cardinal Health 107, LLC × 2 listings | ANDA | View NDC → |
| 2 mg | Oral | Coupler, LLC | ANDA | View NDC → |
| 1 mg | Oral | Coupler LLC | ANDA | View NDC → |
| 2 mg | Oral | Coupler LLC | ANDA | View NDC → |
| 5 mg | Oral | Coupler LLC × 3 listings | ANDA | View NDC → |
| 1 mg | Oral | Direct_Rx | ANDA | View NDC → |
| 2 mg | Oral | Direct_Rx | ANDA | View NDC → |
| 5 mg | Oral | Direct_Rx | ANDA | View NDC → |
| 1 mg | Oral | Exelan Pharmaceuticals | ANDA | View NDC → |
| 2 mg | Oral | Exelan Pharmaceuticals | ANDA | View NDC → |
| 5 mg | Oral | Exelan Pharmaceuticals | ANDA | View NDC → |
| 1 mg | Oral | Granules Pharmaceuticals Inc. | ANDA | View NDC → |
| 2 mg | Oral | Granules Pharmaceuticals Inc. | ANDA | View NDC → |
| 5 mg | Oral | Granules Pharmaceuticals Inc. | ANDA | View NDC → |
| 1 mg | Oral | Lannett Company, Inc. | ANDA | View NDC → |
| 2 mg | Oral | Lannett Company, Inc. | ANDA | View NDC → |
| 5 mg | Oral | Lannett Company, Inc. | ANDA | View NDC → |
| 1 mg | Oral | Lifestar Pharma LLC | ANDA | View NDC → |
| 2 mg | Oral | Lifestar Pharma LLC | ANDA | View NDC → |
| 5 mg | Oral | Lifestar Pharma LLC | ANDA | View NDC → |
| 1 mg | Oral | Major Pharmaceuticals | ANDA | View NDC → |
| 2 mg | Oral | Major Pharmaceuticals | ANDA | View NDC → |
| 5 mg | Oral | Major Pharmaceuticals | ANDA | View NDC → |
| 1 mg | Oral | Marlex Pharmaceuticals Inc | ANDA | View NDC → |
| 2 mg | Oral | Marlex Pharmaceuticals Inc | ANDA | View NDC → |
| 5 mg | Oral | Marlex Pharmaceuticals Inc | ANDA | View NDC → |
| 1 mg | Oral | Mylan Institutional Inc. | ANDA | View NDC → |
| 2 mg | Oral | Mylan Institutional Inc. | ANDA | View NDC → |
| 5 mg | Oral | Mylan Institutional Inc. | ANDA | View NDC → |
| 1 mg | Oral | Mylan Pharmaceuticals Inc. | ANDA | View NDC → |
| 2 mg | Oral | Mylan Pharmaceuticals Inc. | ANDA | View NDC → |
| 5 mg | Oral | Mylan Pharmaceuticals Inc. | ANDA | View NDC → |
| 1 mg | Oral | NCS HealthCare of KY, LLC dba Vangard Labs | ANDA | View NDC → |
| 2 mg | Oral | NCS HealthCare of KY, LLC dba Vangard Labs | ANDA | View NDC → |
| 1 mg | Oral | Novadoz Pharmaceuticals LLC | ANDA | View NDC → |
| 2 mg | Oral | Novadoz Pharmaceuticals LLC | ANDA | View NDC → |
| 5 mg | Oral | Novadoz Pharmaceuticals LLC | ANDA | View NDC → |
| 2 mg | Oral | NuCare Pharmaceuticals,Inc. | ANDA | View NDC → |
| 1 mg | Oral | PD-Rx Pharmaceuticals, Inc. | ANDA | View NDC → |
| 2 mg | Oral | PD-Rx Pharmaceuticals, Inc. | ANDA | View NDC → |
| 5 mg | Oral | PD-Rx Pharmaceuticals, Inc. | ANDA | View NDC → |
| 1 mg | Oral | Prasco Laboratories | NDA AUTHORIZED GENERIC | View NDC → |
| 2 mg | Oral | Prasco Laboratories | NDA AUTHORIZED GENERIC | View NDC → |
| 5 mg | Oral | Prasco Laboratories | NDA AUTHORIZED GENERIC | View NDC → |
| 1 mg | Oral | Preferred Pharmaceuticals Inc. | ANDA | View NDC → |
| 2 mg | Oral | Preferred Pharmaceuticals Inc. | ANDA | View NDC → |
| 5 mg | Oral | Preferred Pharmaceuticals Inc. | ANDA | View NDC → |
| 2 mg | Oral | Proficient Rx LP | ANDA | View NDC → |
| 5 mg | Oral | Proficient Rx LP × 2 listings | ANDA | View NDC → |
| 1 mg | Oral | Remedyrepack Inc. × 5 listings | ANDA | View NDC → |
| 1 mg | Oral | Remedyrepack Inc. | NDA AUTHORIZED GENERIC | View NDC → |
| 2 mg | Oral | Remedyrepack Inc. × 3 listings | ANDA | View NDC → |
| 5 mg | Oral | Remedyrepack Inc. × 3 listings | ANDA | View NDC → |
| 1 mg | Oral | Safecor Health LLC | ANDA | View NDC → |
| 2 mg | Oral | Safecor Health LLC | ANDA | View NDC → |
| 5 mg | Oral | Safecor Health LLC | ANDA | View NDC → |
| 1 mg | Oral | St. Mary's Medical Park Pharmacy | ANDA | View NDC → |
Showing 105 of 111 products — FDA National Drug Code Directory. See every product, package size and price: browse all 111 Prazosin NDCs →
Prazosin side effects reported to the FDA (FAERS)
After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Prazosin — a signal of what to watch for, not proof the drug caused it.
Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Prazosin in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.
Prazosin FDA approval history
How Prazosin went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.
Source: Drugs@FDA.
Prazosin recall history
A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.
The FDA’s enforcement reports list 4 Prazosin recalls since July 2021, covering 10 product listings. Three of them are still ongoing or began in the last six months and are listed first. A recall names specific lots from one company, so check the lot number on your own bottle rather than assuming every product is affected; your pharmacist can check whether your supply came from an affected lot.
- Prazosin Hydrochloride Capsules, USP, 5mg, 100-count bottle, Rx Only, Manufactured for: Biocon Pharma Inc., Iselin, NJ, Manufactured by: Appco Pharma LLC, Piscataway, NJ, NDC 70377-068-11. Lots: Lot:2406255UC, Exp.: 2026/MAY; 2406256UC, Exp.: 2026/JUL; 2407313UC Exp.: 2026/JUL; 2408351UC, Exp.: 2026/JUL; 2408352UC , Exp.: 2026/JUL; 2509311UC, Exp.: 2027/SEP. . FDA record D-0421-2026 →
- Prazosin Hydrochloride Capsules, USP, 2mg, 100-count bottle, Rx Only, Manufactured for: Biocon Pharma Inc., Iselin, NJ, Manufactured by: Appco Pharma LLC, Piscataway, NJ, NDC 70377-067-11. Lots: Lot:2404153UC, Exp.: 2026/MAR; 2404154UC, Exp.:2026/MAR; 2502055UC, Exp.: 2027/JAN; 2505173UC, Exp.: 2027/MAY; 2505175UC, Exp.: 2027/MAY. FDA record D-0420-2026 →
- Prazosin Hydrochloride Capsules, USP, 1mg, 100-count bottle, Rx Only, Manufactured for: Biocon Pharma Inc., Iselin, NJ, Manufactured by: Appco Pharma LLC, Piscataway, NJ, NDC 70377-066-11. Lots: Lot:2404160C, Exp.:2026/MAR; 2406253C, Exp.:2026/MAY; 2407311C, Exp.: 2026/JUL; 2407312C, Exp.:2026/JUL; 2408350C, Exp.:2026/JUL; 2505172C, Exp.:2027/MAY; 2506191C, Exp.: 2027/JUN. FDA record D-0419-2026 →
- Prazosin Hydrochloride, Capsules, USP, 5 mg, 20 capsules (5x4) cartons, Rx only, Distributed by American Health Packaging, Columbus, Ohio 43217, carton NDC 60687-572-32, Individual unit dose: NDC 606… Lots: Lot #: 1016996, 1018336, 1021220, Exp. Date 11/30/2025; 1022421, 1025017, Exp. Date 08/31/2026. FDA record D-0103-2026 →
- Prazosin Hydrochloride, Capsules, USP, 2 mg, 100 capsules (10x10) cartons, Rx only, Distributed by American Health Packaging, Columbus, Ohio 43217, Carton NDC 68084-997-01, Individual unit dose: NDC… Lots: Lot #: 1020109, Exp. Date 02/28/2026; 1024343, 1025355, Exp. Date 09/30/2026. FDA record D-0102-2026 →
- Prazosin Hydrochloride, Capsules, USP, 1 mg, 100 capsules (10x10) cartons, Rx only, Distributed by American Health Packaging, Columbus, Ohio 43217, Carton NDC 68084-996-01. Individual unit dose: NDC… Lots: Lot #: 1023526, 1023555, Expiry: 07/31/2026 FDA record D-0101-2026 →
- Prazosin Hydrochloride, Capsules, USP, 5 mg, Rx only, Distributed by TEVA PHARMACEUTICALS USA, INC., North Wales, PA 19454, a) 100 Capsules, NDC 0093-4069-01, b) 250 Capsules, NDC 0093-4069-52, c) 50… Lots: a) NDC 0093-4069-01: Lot # 3010403A, 3010385A, 3010404A, Exp Date: 02/2026; Lot # 3010405A, 3010510A, 3010528A, 3010354A, Exp Date: 03/2026; Lot # 3010592A, 3010605A, 3010611A, 3010612A, Exp Date: 08/2026; Lot # 3010655A, 3010703A, Exp Dat… FDA record D-0106-2026 →
- Prazosin Hydrochloride, Capsules, USP, 2 mg, Rx only, Distributed by TEVA PHARMACEUTICALS USA, INC., North Wales, PA 19454, a) 100 Capsules, NDC 0093-4068-01, b) 1000 Capsules, NDC 0093-4068-10 Lots: a) NDC 0093-4068-01: Lot # 3010398A, 3010399A, 3010400A, 3010401A, 3010353A, Exp Date: 12/2025; Lot # 3010439A, 3010388A, Exp Date: 01/2026; Lot # 3010526A, 3010527A, Exp Date: 03/2026; Lot # 3010591A, 07/2026; Lot # 3010343A, Exp Date: 10… FDA record D-0105-2026 →
- Prazosin Hydrochloride, Capsules, USP, 1 mg, Rx only, Distributed by TEVA PHARMACEUTICALS USA, INC., North Wales, PA 19454, a) 100 Capsules, NDC 0093-4067-01, b) 1000 Capsules, NDC 0093-4067-10 Lots: a) NDC 0093-4067-01: Lot # 3010544A and 3010545A, Exp Date: 10/2025; Lot # 3010567A, Exp Date: 12/2025; Lot # 3010590A, Exp Date: 02/2026; Lot # 3010601A, 3010602A, 3010603A, Exp Date: 03/2026; Lot # 3010652A, 3010670A, 3010671A, Exp Date:… FDA record D-0104-2026 →
- Prazosin Hydrochloride Capsules, USP, 1 mg, 100-count bottle, Rx only, MFG: Mylan Pharma, NDC 0378-1101-01 Lots: McKesson Medical-Surgical (MMS) is not able to identify the particular lot number received by a particular consignee for the recalled prescription products. Each letter includes the date it was distributed to customers and the dates that i… FDA record D-1093-2022 →
Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.
RxNorm Concept Web — From Ingredient to Every Form and Strength
This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.
RxCUI 8629 3 dose forms · 8 strengths
-
Dose form (SCDF) Extended Release Oral Tablet RxCUI 451067No current FDA listingClinical drug / strength (SCD) 5 MGRxCUI 431751 -
Dose form (SCDF) Oral Capsule RxCUI 373565In current FDA listings -
Dose form (SCDF) Oral Tablet RxCUI 373567In current FDA listingsClinical drug / strength (SCD) 0.5 MGRxCUI 1997961 MGRxCUI 1997972 MGRxCUI 1997985 MGRxCUI 199799
Look up RxCUI 8629 in the RxCUI Atlas →
RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.
Prazosin supply and shortage status
Whether Prazosin is in short supply in the U.S. right now, plus any shortage history the FDA has on record. A shortage usually reflects a manufacturing or demand issue — not a safety problem with the drug.
Source: openFDA, from the FDA Drug Shortages database.
💵 What Prazosin costs pharmacies (NADAC benchmark)
The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.
| Form | Strength | Pharmacy acquisition benchmark | |
|---|---|---|---|
| Capsule · Oral | 1 mg | $0.084 per capsule | NDC details & price history |
| Capsule · Oral | 2 mg | $0.086 per capsule | NDC details & price history |
| Capsule · Oral | 5 mg | $0.134 per capsule | NDC details & price history |
Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.
Prazosin brand names
Prazosin is sold under 2 brand names in the FDA directory — Minipress, Minipress XL. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.
Who makes Prazosin: manufacturers and labelers
33 companies list Prazosin products with the FDA. By number of product records, the largest are Remedyrepack Inc., Bryant Ranch Prepack, Coupler LLC. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.
…and 9 more on the FDA NDC directory.
Prazosin drug class (RxNorm)
Prazosin belongs to the alpha-Adrenergic Blocker class.
Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.
Sources for this Prazosin page
Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.
How this page is built
HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Lannett Company, Inc. is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →