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Prazosin

Prazosin is an alpha-blocker-type blood pressure medicine taken by mouth as a capsule to treat high blood pressure (hypertension), alone or with other blood pressure drugs.

Brand names MinipressMinipress XL
Drug class Alpha-adrenergic Blocker
Rx Forms 2
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 2, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 77 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

Prazosin at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

Prazosin (Minipress) is an older alpha-blocker for high blood pressure that relaxes small blood vessels, lowering the risk of stroke and heart attack; on the market since the mid-1970s and available generically, it is now usually an add-on rather than a first choice. Most people tolerate it reasonably well once settled on a dose, though dizziness, headache, drowsiness and low energy are the side effects people notice most. The thing to watch for is fainting from a sudden drop in blood pressure, most often within 30 to 90 minutes of the first dose, after a dose increase or when another blood pressure drug is added.

Clinical pearls

  • Take the very first dose at bedtime and get up slowly at night, since the first-dose drop can cause fainting.
  • Tell your eye surgeon before cataract surgery, because prazosin can cause floppy iris syndrome, a pupil problem during the operation.
  • Erectile dysfunction medicines (PDE-5 inhibitors) add to the blood pressure drop, so they should be started at the lowest dose.
  • Rarely it causes an erection lasting over 4 hours, which needs emergency care to prevent permanent damage.
How you get itPrescription only
Comes asCapsule, Tablet
Earliest FDA record1976
Companies listing it with the FDA33
FDA label last updatedSep 15, 2023
FDA’s strongest warning (boxed)None on the label

Patient information guide A plain-language walkthrough of Prazosin, written from its FDA label.

What Prazosin is used for

▾

Prazosin is approved for one main use, based on the oral capsule products:

  • High blood pressure (hypertension): Prazosin, Prazosin HCL and Prazosin Hydrochloride capsules lower blood pressure.
  • They can be used alone or combined with other blood pressure medicines such as diuretics or beta-blockers.
  • Lowering blood pressure reduces the risk of strokes and heart attacks.

How Prazosin works

▾

Prazosin lowers total peripheral resistance, meaning it relaxes and widens small arteries so blood flows more easily. It is thought to work partly by blocking alpha-adrenoceptors on blood vessels. The exact mechanism is not known.

Unlike conventional alpha-blockers, it usually does not cause a reflex fast heartbeat, and tolerance has not been seen with long-term use.

Prazosin dosage

▾

Prazosin capsules are taken by mouth, usually two or three times a day at first. Some people can later do well on twice daily. The dose is raised slowly based on your blood pressure.

  • Treatment always begins with the lowest-strength capsule.
  • If another blood pressure drug is added, the prazosin dose may be lowered and adjusted again.
  • Follow your prescriber and pharmacy label for timing and amounts.

Dosing details from the FDA-approved label

From the Prazosin prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Initial dose
    • 1 mg two or three times a day
  • Maintenance dose
    • Dosage may be slowly increased to a total daily dose of 20 mg given in divided doses
    • The therapeutic dosages most commonly employed have ranged from 6 mg to 15 mg daily given in divided doses
    • After initial titration some patients can be maintained adequately on a twice daily dosage regimen
    • Maximum: Doses higher than 20 mg usually do not increase efficacy, however a few patients may benefit from further increases up to a daily dose of 40 mg given in divided doses.
  • Use with a diuretic or other antihypertensive agent
    • Reduce the prazosin dose to 1 mg or 2 mg three times a day and then carry out retitration
  • Use with a PDE-5 inhibitor
    • PDE-5 inhibitor therapy should be initiated at the lowest dose in patients taking prazosin
    • Concomitant use can result in additive blood pressure lowering effects and symptomatic hypotension
Read the label’s full dosing text

DOSAGE AND ADMINISTRATION The dose of prazosin hydrochloride capsules should be adjusted according to the patient’s individual blood pressure response. The following is a guide to its administration: Initial Dose: 1 mg two or three times a day (see WARNINGS ). Maintenance Dose: Dosage may be slowly increased to a total daily dose of 20 mg given in divided doses. The therapeutic dosages most commonly employed have ranged from 6 mg to 15 mg daily given in divided doses. Doses higher than 20 mg usually do not increase efficacy, however a few patients may benefit from further increases up to a daily dose of 40 mg given in divided doses. After initial titration some patients can be maintained adequately on a twice daily dosage regimen. Use With Other Drugs: When adding a diuretic or other antihypertensive agent, the dose of prazosin hydrochloride capsules should be reduced to 1 mg or 2 mg three times a day and retitration then carried out. Concomitant administration of prazosin hydrochloride capsules with a PDE-5 inhibitor can result in additive blood pressure lowering effects and symptomatic hypotension; therefore, PDE-5 inhibitor therapy should be initiated at the lowest dose in patients taking prazosin hydrochloride capsules.

Read the full Dosage and Administration section on DailyMed →

Prazosin side effects

▾

Many side effects ease with continued use. The most common are:

Common side effects

  • Dizziness
  • Headache
  • Drowsiness
  • Lack of energy
  • Weakness
  • Palpitations (feeling your heartbeat)
  • Nausea

When to get medical help

  • Fainting (sudden loss of consciousness): call your doctor, especially if it happens after your first dose or a dose increase.
  • An erection lasting longer than 4 hours: get immediate medical help to avoid permanent damage.
  • Signs of an allergic reaction such as hives or rash: contact your doctor right away.
  • Chest pain (angina), very slow heartbeat or severe low blood pressure: seek medical help.
  • Hallucinations or worsening depression: tell your doctor.

Prazosin warnings and precautions

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  • Fainting: can occur suddenly, most often within 30 to 90 minutes of the first dose or after a quick dose increase. If it happens, lie down.
  • Dizziness and lightheadedness: avoid situations where a fall could cause injury when starting.
  • Priapism: a prolonged erection over 4 hours needs immediate care; delay can cause permanent loss of potency.
  • Eye surgery: alpha-1 blockers can cause Intraoperative Floppy Iris Syndrome during cataract surgery.
  • Narcolepsy: worsening has been reported, though a cause is uncertain.

Prazosin interactions

▾

Other medicines that lower blood pressure can add to prazosin’s effect.

  • Diuretics and other blood pressure drugs: additive blood pressure lowering, so doses may be adjusted.
  • Beta-blockers such as propranolol: may cause low blood pressure.
  • PDE-5 inhibitors: can cause symptomatic low blood pressure; they should be started at the lowest dose.
  • Pheochromocytoma screening tests: prazosin may cause false positives.

Interactions listed in the FDA-approved label

From the Prazosin prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.

  • Diuretic or other antihypertensive agent: Addition to prazosin has been shown to cause an additive hypotensive effect. Reduce the prazosin dose to 1 to 2 mg three times a day, introduce additional antihypertensive drugs cautiously, and then retitrate prazosin based on clinical response.
  • Phosphodiesterase-5 (PDE-5) inhibitors: Concomitant administration can result in additive blood pressure lowering effects and symptomatic hypotension. PDE-5 inhibitor therapy should be initiated at the lowest dose in patients taking prazosin (see Dosage and Administration).
  • Cardiac glycosides (digitalis, digoxin): Administered without any adverse drug interaction in limited clinical experience to date.
  • Hypoglycemics (insulin, chlorpropamide, phenformin, tolazamide, tolbutamide): Administered without any adverse drug interaction in limited clinical experience to date.
  • Tranquilizers and sedatives (chlordiazepoxide, diazepam, phenobarbital): Administered without any adverse drug interaction in limited clinical experience to date.
  • Antigout drugs (allopurinol, colchicine, probenecid): Administered without any adverse drug interaction in limited clinical experience to date.
  • Antiarrhythmics (procainamide, propranolol, quinidine): Administered without any adverse drug interaction in limited clinical experience to date. For propranolol, see WARNINGS.
  • Analgesics, antipyretics and anti-inflammatories (propoxyphene, aspirin, indomethacin, phenylbutazone): Administered without any adverse drug interaction in limited clinical experience to date.
  • Screening tests for pheochromocytoma (urinary VMA and norepinephrine metabolite): In five patients given 12 to 24 mg of prazosin per day for 10 to 14 days, urinary metabolite of norepinephrine increased an average of 42% and urinary VMA an average of 17%, so false positive results may occur. If an elevated VMA is found, prazosin should be discontinued and the patient retested after a month.
Read the label’s full interactions text

Interactions Drug Interactions Prazosin hydrochloride capsules have been administered without any adverse drug interaction in limited clinical experience to date with the following: (1) cardiac glycosides‒digitalis and digoxin; (2) hypoglycemics‒insulin, chlorpropamide, phenformin, tolazamide, and tolbutamide; (3) tranquilizers and sedatives‒chlordiazepoxide, diazepam, and phenobarbital; (4) antigout‒allopurinol, colchicine, and probenecid; (5) antiarrhythmics‒procainamide, propranolol (see WARNINGS however), and quinidine; and (6) analgesics, antipyretics and anti-inflammatories-propoxyphene, aspirin, indomethacin, and phenylbutazone. Addition of a diuretic or other antihypertensive agent to prazosin hydrochloride capsules have been shown to cause an additive hypotensive effect. This effect can be minimized by reducing the prazosin hydrochloride capsules dose to 1 to 2 mg three times a day, by introducing additional antihypertensive drugs cautiously, and then by retitrating prazosin hydrochloride capsules based on clinical response. Concomitant administration of prazosin hydrochloride capsules with a phosphodiesterase-5 (PDE-5) inhibitor can result in additive blood pressure lowering effects and symptomatic hypotension (see DOSAGE AND ADMINISTRATION ). Drug/Laboratory Test Interactions In a study on five patients given from 12 to 24 mg of prazosin per day for 10 to 14 days, there was an average increase of 42% in the urinary metabolite of norepinephrine and an average increase in urinary VMA of 17%. Therefore, false positive results may occur in screening tests for pheochromocytoma in patients who are being treated with prazosin. If an elevated VMA is found, prazosin should be discontinued and the patient retested after a month.

Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →

Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.

Before taking Prazosin

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  • Do not take it if you are allergic to prazosin, quinazolines or any inactive ingredient.
  • Tell your doctor about all blood pressure medicines and PDE-5 inhibitors you use.
  • Tell your eye surgeon you take prazosin before cataract surgery.
  • Mention narcolepsy if you have it.

Prazosin overdose

▾

In one report, a two-year-old who swallowed at least 50 mg had profound drowsiness and depressed reflexes but recovered fully. If overdose causes low blood pressure, treatment focuses on supporting the heart and circulation, such as lying flat, fluids and, if needed, medicines to raise blood pressure. Prazosin is not removed by dialysis.

What Prazosin does in the body

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Prazosin lowers blood pressure in both lying and standing positions, with the strongest effect on diastolic pressure (the bottom number). It does not significantly change cardiac output, heart rate, kidney blood flow or kidney filtration. It has not raised plasma renin activity, and lipid levels generally showed no adverse changes.

How your body processes Prazosin

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After a dose by mouth, blood levels peak at about three hours, and the half-life is two to three hours. Prazosin is highly bound to proteins in the blood. It is extensively metabolized and excreted mainly through bile and feces.

How to store Prazosin

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Store at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F) . Dispense in a tight, light-resistant containers (USP).

Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

137

Supplements & herbs that interact with Prazosin

137 supplements and herbal products have documented interactions with Prazosin in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 4
  • Moderate · 112
  • Minor · 21
Every supplement checked against Prazosin — ranked by severity The full interaction hub: 4 major · 112 moderate · 21 minor · every one linked to its full report. Check Prazosin against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

1

Nutrient depletion considerations

Prazosin has been associated with lower levels of 1 nutrient in the clinical literature. This does not mean a deficiency will occur — it means these may be worth discussing with your pharmacist or healthcare provider, especially with long-term use.

See the full Prazosin nutrient depletion report

Educational information from a licensed clinical database (Natural Medicines) — not medical advice. Do not start or stop medications or supplements without professional guidance.

Prazosin: pharmacist answers to common questions

Quick, plain-English answers to the questions patients ask most about Prazosin — the kind of thing our pharmacy team would talk through with you at the counter.

What is prazosin for?

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It treats high blood pressure. Bringing your pressure down lowers your risk of stroke and heart attack. It can be taken alone or with other blood pressure medicines like water pills or beta-blockers.

How should I take it?

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Prazosin capsules are taken by mouth, usually two or three times a day at first. Your prescriber will start you low and raise the dose slowly based on your blood pressure. Take it exactly as your label says.

Why am I dizzy after my first dose?

▾
Prazosin can drop your blood pressure quickly, especially in the first hours after a first dose or an increase. Dizziness is common, and fainting is less common. Be careful standing up and avoid situations where a fall could hurt you. Call your doctor if you faint.

What side effects are normal?

▾
Dizziness, headache, drowsiness, low energy, weakness, palpitations and nausea are the most common. These often fade with continued use. Call your doctor if they are bothersome or don’t go away.

When should I get urgent help?

▾
Get immediate help if you have an erection lasting longer than 4 hours, since it can cause permanent damage. Also seek help for fainting, chest pain or signs of an allergic reaction like hives.

Can I take it with other medicines?

▾
Check with me first. Other blood pressure drugs and erectile dysfunction medicines (PDE-5 inhibitors) can lower your blood pressure further, so doses may need adjusting. Also tell your eye surgeon you take prazosin before cataract surgery.

Is Prazosin available over the counter?

▾
No. Prazosin is a prescription medicine: every Prazosin product listed with the FDA is prescription only, so it is not sold over the counter. Your prescriber decides whether it is appropriate for you, and your pharmacist dispenses it.

When was Prazosin first available?

▾
The earliest FDA record we hold for Prazosin is from 1976: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Prazosin was first used.

Who makes Prazosin?

▾
33 companies currently list Prazosin products in the FDA's NDC Directory, including Remedyrepack Inc., Bryant Ranch Prepack, Coupler LLC. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

More about Prazosin on HelloPharmacist

Detailed data & references for Prazosin Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

Prazosin forms and strengths (how it comes)

Prazosin is available in 2 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Capsule

By mouth
Brands Minipress
How this form is used
What it may be used for
  • Prazosin, Prazosin HCL and Prazosin Hydrochloride capsules are used to treat high blood pressure.
  • Prazosin, Prazosin HCL and Prazosin Hydrochloride capsules can be used alone or with diuretics or beta-blockers.
Important instructions
  • Prazosin, Prazosin HCL and Prazosin Hydrochloride capsules are taken by mouth, usually two or three times a day to start.
  • Prazosin, Prazosin HCL and Prazosin Hydrochloride capsules are adjusted to your blood pressure response.
  • Prazosin, Prazosin HCL and Prazosin Hydrochloride capsules should always be started at the lowest capsule strength.
Available strengths 3 strengths
209 FDA-listed product records ⓘ

Tablet

By mouth
Available strengths 2 strengths
2 FDA-listed product records ⓘ

Prazosin on the U.S. market: products, makers and brands

How Prazosin appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

33 companies list 111 Prazosin product records with the FDA, mostly as capsule, tablet; the earliest marketing or approval year on record is 1976. Brand names on the directory include Minipress, Minipress XL; the rest are generics.

2
Dose forms ⓘ
33
Labelers (makers, repackagers, distributors)
3
Brand names
111
FDA-listed product records ⓘ
1976
Earliest FDA record ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Powder (9) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Remedyrepack Inc.11%
Bryant Ranch Prepack7%
Coupler LLC5%
Aphena Pharma Solutions - Tennessee, LLC5%
ANI Pharmaceuticals, Inc.3%
Asclemed Usa Inc.3%
Other makers67%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Prazosin is used (Medicaid data)

A general measure of how commonly Prazosin is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Prazosin is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

2,024,285
Medicaid prescriptions filled (Q1–Q4 2025)
$26.6M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Prazosin prescribed? Of the 1,601 medications we measure, Prazosin ranks #111 by Medicaid prescriptions — more than 93% of them.

Where Prazosin ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5

Utilization by Prazosin product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 1 mg oral capsule is the most-dispensed Prazosin product — about 48% of these Medicaid prescriptions.

prazosin 1 MG Oral Capsule Most dispensed

964,246 Medicaid prescriptions (Q1–Q4 2025) 48% of Prazosin prescriptions shown $11.9M gross reimbursement (before rebates) ≈ $12 per prescription (gross)

Summed across the 20 of 126 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 312593

prazosin 2 MG Oral Capsule

789,034 Medicaid prescriptions (Q1–Q4 2025) 39% of Prazosin prescriptions shown $10M gross reimbursement (before rebates) ≈ $13 per prescription (gross)

Summed across the 18 of 114 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 312594

prazosin 5 MG Oral Capsule

271,005 Medicaid prescriptions (Q1–Q4 2025) 13% of Prazosin prescriptions shown $4.6M gross reimbursement (before rebates) ≈ $17 per prescription (gross)

Summed across the 18 of 98 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 198141

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Prazosin, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 56 of 338 listed Prazosin NDCs with Medicaid activity.

Compare Prazosin products

A representative set of FDA-listed product records for Prazosin — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 105 of 111 products — FDA National Drug Code Directory. See every product, package size and price: browse all 111 Prazosin NDCs →

Prazosin recall history

A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

The FDA’s enforcement reports list 4 Prazosin recalls since July 2021, covering 10 product listings. Three of them are still ongoing or began in the last six months and are listed first. A recall names specific lots from one company, so check the lot number on your own bottle rather than assuming every product is affected; your pharmacist can check whether your supply came from an affected lot.

Ongoing Class II Mar 27, 2026 · Appco Pharma LLC
cGMP deviation: detection of Nitrosamine Drug Substance-Related Impurities, N-nitroso-prazosin impurity C (NNP) above acceptable limits.
  • Prazosin Hydrochloride Capsules, USP, 5mg, 100-count bottle, Rx Only, Manufactured for: Biocon Pharma Inc., Iselin, NJ, Manufactured by: Appco Pharma LLC, Piscataway, NJ, NDC 70377-068-11. Lots: Lot:2406255UC, Exp.: 2026/MAY; 2406256UC, Exp.: 2026/JUL; 2407313UC Exp.: 2026/JUL; 2408351UC, Exp.: 2026/JUL; 2408352UC , Exp.: 2026/JUL; 2509311UC, Exp.: 2027/SEP. . FDA record D-0421-2026 →
  • Prazosin Hydrochloride Capsules, USP, 2mg, 100-count bottle, Rx Only, Manufactured for: Biocon Pharma Inc., Iselin, NJ, Manufactured by: Appco Pharma LLC, Piscataway, NJ, NDC 70377-067-11. Lots: Lot:2404153UC, Exp.: 2026/MAR; 2404154UC, Exp.:2026/MAR; 2502055UC, Exp.: 2027/JAN; 2505173UC, Exp.: 2027/MAY; 2505175UC, Exp.: 2027/MAY. FDA record D-0420-2026 →
  • Prazosin Hydrochloride Capsules, USP, 1mg, 100-count bottle, Rx Only, Manufactured for: Biocon Pharma Inc., Iselin, NJ, Manufactured by: Appco Pharma LLC, Piscataway, NJ, NDC 70377-066-11. Lots: Lot:2404160C, Exp.:2026/MAR; 2406253C, Exp.:2026/MAY; 2407311C, Exp.: 2026/JUL; 2407312C, Exp.:2026/JUL; 2408350C, Exp.:2026/JUL; 2505172C, Exp.:2027/MAY; 2506191C, Exp.: 2027/JUN. FDA record D-0419-2026 →
Ongoing Class II Oct 16, 2025 · Amerisource Health Services LLC
Failed Impurities/Degradation Specification: presence of N-nitroso Prazosin impurity C above the Carcinogenic Potency Categorization Approach (CPCA) acceptable intake limit
  • Prazosin Hydrochloride, Capsules, USP, 5 mg, 20 capsules (5x4) cartons, Rx only, Distributed by American Health Packaging, Columbus, Ohio 43217, carton NDC 60687-572-32, Individual unit dose: NDC 606… Lots: Lot #: 1016996, 1018336, 1021220, Exp. Date 11/30/2025; 1022421, 1025017, Exp. Date 08/31/2026. FDA record D-0103-2026 →
  • Prazosin Hydrochloride, Capsules, USP, 2 mg, 100 capsules (10x10) cartons, Rx only, Distributed by American Health Packaging, Columbus, Ohio 43217, Carton NDC 68084-997-01, Individual unit dose: NDC… Lots: Lot #: 1020109, Exp. Date 02/28/2026; 1024343, 1025355, Exp. Date 09/30/2026. FDA record D-0102-2026 →
  • Prazosin Hydrochloride, Capsules, USP, 1 mg, 100 capsules (10x10) cartons, Rx only, Distributed by American Health Packaging, Columbus, Ohio 43217, Carton NDC 68084-996-01. Individual unit dose: NDC… Lots: Lot #: 1023526, 1023555, Expiry: 07/31/2026 FDA record D-0101-2026 →
Ongoing Class II Oct 7, 2025 · Teva Pharmaceuticals USA, Inc
CGMP Deviations-Test results for N-nitroso Prazosin impurity C that are above the Carcinogenic Potency Categorization Approach (CPCA) acceptable intake limit for the above specified lots.
  • Prazosin Hydrochloride, Capsules, USP, 5 mg, Rx only, Distributed by TEVA PHARMACEUTICALS USA, INC., North Wales, PA 19454, a) 100 Capsules, NDC 0093-4069-01, b) 250 Capsules, NDC 0093-4069-52, c) 50… Lots: a) NDC 0093-4069-01: Lot # 3010403A, 3010385A, 3010404A, Exp Date: 02/2026; Lot # 3010405A, 3010510A, 3010528A, 3010354A, Exp Date: 03/2026; Lot # 3010592A, 3010605A, 3010611A, 3010612A, Exp Date: 08/2026; Lot # 3010655A, 3010703A, Exp Dat… FDA record D-0106-2026 →
  • Prazosin Hydrochloride, Capsules, USP, 2 mg, Rx only, Distributed by TEVA PHARMACEUTICALS USA, INC., North Wales, PA 19454, a) 100 Capsules, NDC 0093-4068-01, b) 1000 Capsules, NDC 0093-4068-10 Lots: a) NDC 0093-4068-01: Lot # 3010398A, 3010399A, 3010400A, 3010401A, 3010353A, Exp Date: 12/2025; Lot # 3010439A, 3010388A, Exp Date: 01/2026; Lot # 3010526A, 3010527A, Exp Date: 03/2026; Lot # 3010591A, 07/2026; Lot # 3010343A, Exp Date: 10… FDA record D-0105-2026 →
  • Prazosin Hydrochloride, Capsules, USP, 1 mg, Rx only, Distributed by TEVA PHARMACEUTICALS USA, INC., North Wales, PA 19454, a) 100 Capsules, NDC 0093-4067-01, b) 1000 Capsules, NDC 0093-4067-10 Lots: a) NDC 0093-4067-01: Lot # 3010544A and 3010545A, Exp Date: 10/2025; Lot # 3010567A, Exp Date: 12/2025; Lot # 3010590A, Exp Date: 02/2026; Lot # 3010601A, 3010602A, 3010603A, Exp Date: 03/2026; Lot # 3010652A, 3010670A, 3010671A, Exp Date:… FDA record D-0104-2026 →
Class II Apr 13, 2022 · Terminated · Mckesson Medical-Surgical Inc. Corporate Office
cGMP deviations: Temperature abuse
  • Prazosin Hydrochloride Capsules, USP, 1 mg, 100-count bottle, Rx only, MFG: Mylan Pharma, NDC 0378-1101-01 Lots: McKesson Medical-Surgical (MMS) is not able to identify the particular lot number received by a particular consignee for the recalled prescription products. Each letter includes the date it was distributed to customers and the dates that i… FDA record D-1093-2022 →

Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Prazosin RxCUI 8629 3 dose forms · 8 strengths
  1. Dose form (SCDF) Extended Release Oral Tablet RxCUI 451067 No current FDA listing
    Clinical drug / strength (SCD) 5 MG RxCUI 431751
  2. Dose form (SCDF) Oral Capsule RxCUI 373565 In current FDA listings
    Clinical drug / strength (SCD) 1 MG RxCUI 312593 2 MG RxCUI 312594 5 MG RxCUI 198141
  3. Dose form (SCDF) Oral Tablet RxCUI 373567 In current FDA listings
    Clinical drug / strength (SCD) 0.5 MG RxCUI 199796 1 MG RxCUI 199797 2 MG RxCUI 199798 5 MG RxCUI 199799

Look up RxCUI 8629 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

💵 What Prazosin costs pharmacies (NADAC benchmark)

The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.

FormStrengthPharmacy acquisition benchmark
Capsule · Oral 1 mg $0.084 per capsule NDC details & price history
Capsule · Oral 2 mg $0.086 per capsule NDC details & price history
Capsule · Oral 5 mg $0.134 per capsule NDC details & price history
Why show this? Your out-of-pocket cost depends on insurance, pharmacy markup, and discounts — but the acquisition benchmark tells you whether the medication itself is inexpensive or costly, which strengths cost more per dose, and whether a cash-price quote is in a reasonable range. Each row links to the NDC-level record with its full price history.

Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.

Prazosin brand names

Prazosin is sold under 2 brand names in the FDA directory — Minipress, Minipress XL. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Minipress Minipress XL

Who makes Prazosin: manufacturers and labelers

33 companies list Prazosin products with the FDA. By number of product records, the largest are Remedyrepack Inc., Bryant Ranch Prepack, Coupler LLC. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

Remedyrepack Inc. 12 Bryant Ranch Prepack 8 Coupler LLC 6 Aphena Pharma Solutions - Tennessee, LLC 5 ANI Pharmaceuticals, Inc. 3 Asclemed Usa Inc. 3 Alembic Pharmaceuticals Inc. 3 Alembic Pharmaceuticals Limited 3 American Health Packaging 3 Aurobindo Pharma Limited 3 Biocon Pharma Inc. 3 Direct_Rx 3 Exelan Pharmaceuticals 3 Granules Pharmaceuticals Inc. 3 Lannett Company, Inc. 3 Lifestar Pharma LLC 3 Major Pharmaceuticals 3 Marlex Pharmaceuticals Inc 3 Mylan Institutional Inc. 3 Mylan Pharmaceuticals Inc. 3 Novadoz Pharmaceuticals LLC 3 PD-Rx Pharmaceuticals, Inc. 3 Prasco Laboratories 3 Preferred Pharmaceuticals Inc. 3

…and 9 more on the FDA NDC directory.

Prazosin drug class (RxNorm)

Prazosin belongs to the alpha-Adrenergic Blocker class.

Pharmacologic class alpha-Adrenergic Blocker
Drug family (ATC) Alpha-adrenoreceptor antagonists
How it works Adrenergic alpha-Antagonists

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

Sources for this Prazosin page

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Sep 15, 2023
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Prazosin.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Prazosin after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
77
Finished products in the current FDA directory
111
Companies listing them (makers, repackagers, distributors)
33
FDA labeler codes behind them ⓘ
37
Linked representative label ⓘ
Lannett Company, Inc.
Linked label effective
Sep 15, 2023
Composite sections available
16
Linked SPL Set ID
94021822-60cb-4da6-b809-f565e1d6452d
Linked SPL Document ID
41beba09-90c1-42cc-bfba-ac8a84d09649
Open the linked representative label on DailyMed ↗

How this page is built

HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Lannett Company, Inc. is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →