Valacyclovir

Generic name: Pronounced as (val ay sye' kloe veer)
Brand names
  • Valtrex®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 02/15/2018

Valacyclovir is used to treat herpes zoster (shingles) and genital herpes. It does not cure herpes infections but decreases pain and itching, helps sores to heal, and prevents new ones from forming.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Valacyclovir comes as a tablet to take by mouth. It is usually taken every 8 hours (three times a day) for 7 days to treat shingles. To treat genital herpes it is usually taken twice a day for 5 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take valacyclovir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Use this medication as soon as possible after symptoms appear.

Continue to take valacyclovir even if you feel well. Do not stop taking valacyclovir without talking to your doctor.

Before taking valacyclovir,

  • tell your doctor and pharmacist if you are allergic to acyclovir (Zovirax), valacyclovir, or any other drugs.

  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially cimetidine (Tagamet), probenecid (Benemid), and vitamins.

  • tell your doctor if you have or have ever had kidney or liver disease, problems with your immune system, human immunodeficiency virus infection (HIV), or acquired immunodeficiency syndrome (AIDS).

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking valacyclovir, call your doctor.

Take the missed dose as soon as you remember it, and take any remaining doses for that day at evenly spaced intervals. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Valacyclovir may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • headache

    • upset stomach

    • vomiting

    • diarrhea or loose stools

    • constipation

  • If you experience any of the following side effects, call your doctor immediately:

    • rash

    • itching

    • confusion

    • yellowness of the skin or eyes

    • fever

    • blood in the urine

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to valacyclovir.

Do not have sexual intercourse when you can see the genital herpes lesions. However, genital herpes can be spread even when there are no symptoms.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. If you still have symptoms of infection after you finish the valacyclovir, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Alendronate Alendronate The risk or severity of nephrotoxicity and hypocalcemia can be increased when Valaciclovir is combined with Alendronic acid.
Cilostazol Cilostazol Valaciclovir may decrease the excretion rate of Cilostazol which could result in a higher serum level.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Valaciclovir may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Fenofibrate Fenofibrate Valaciclovir may decrease the excretion rate of Fenofibrate which could result in a higher serum level.
Guanfacine Guanfacine Valaciclovir may decrease the excretion rate of Guanfacine which could result in a higher serum level.
Magnesium Hydroxide Magnesium Hydroxide Valaciclovir may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Mycophenolate Mycophenolate Valaciclovir may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level.
Olsalazine Olsalazine Olsalazine may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Potassium Potassium Valaciclovir may decrease the excretion rate of Potassium cation which could result in a higher serum level.
Prednisone Prednisone Valaciclovir may decrease the excretion rate of Prednisone which could result in a higher serum level.
Ranitidine Ranitidine Valaciclovir may decrease the excretion rate of Ranitidine which could result in a higher serum level.
Reserpine Reserpine Valaciclovir may decrease the excretion rate of Reserpine which could result in a higher serum level.
Rizatriptan Rizatriptan Valaciclovir may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Sumatriptan Sumatriptan Valaciclovir may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus Tacrolimus Tacrolimus may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Tiludronate Tiludronate The risk or severity of nephrotoxicity and hypocalcemia can be increased when Valaciclovir is combined with Etidronic acid.
Ampicillin Injection Ampicillin Injection Valaciclovir may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection Valaciclovir may decrease the excretion rate of Doxycycline which could result in a higher serum level.
Famotidine Injection Famotidine Injection The excretion of Valaciclovir can be decreased when combined with Famotidine.
Fluconazole Injection Fluconazole Injection Valaciclovir may decrease the excretion rate of Fluconazole which could result in a higher serum level.
Foscarnet Injection Foscarnet Injection The risk or severity of nephrotoxicity can be increased when Valaciclovir is combined with Foscarnet.
Hydromorphone Injection Hydromorphone Injection Valaciclovir may decrease the excretion rate of Hydromorphone which could result in a higher serum level.
Levofloxacin Injection Levofloxacin Injection Valaciclovir may decrease the excretion rate of Levofloxacin which could result in a higher serum level.
Meperidine Injection Meperidine Injection Valaciclovir may decrease the excretion rate of Meperidine which could result in a higher serum level.
Metoclopramide Injection Metoclopramide Injection Valaciclovir may decrease the excretion rate of Metoclopramide which could result in a higher serum level.
Pamidronate Injection Pamidronate Injection The risk or severity of nephrotoxicity and hypocalcemia can be increased when Valaciclovir is combined with Pamidronic acid.
Vancomycin Injection Vancomycin Injection Valaciclovir may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Zidovudine Injection Zidovudine Injection The risk or severity of adverse effects can be increased when Valaciclovir is combined with Zidovudine.
Altretamine Altretamine Valaciclovir may decrease the excretion rate of Amphetamine which could result in a higher serum level.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Cyclosporine Cyclosporine Cyclosporine may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Torsemide Torsemide Torasemide may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Meloxicam Meloxicam Meloxicam may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Pantoprazole Pantoprazole Valaciclovir may decrease the excretion rate of Pantoprazole which could result in a higher serum level.
Risedronate Risedronate The risk or severity of nephrotoxicity and hypocalcemia can be increased when Valaciclovir is combined with Risedronic acid.
Temozolomide Temozolomide Valaciclovir may decrease the excretion rate of Temozolomide which could result in a higher serum level.
Zaleplon Zaleplon Valaciclovir may decrease the excretion rate of Zaleplon which could result in a higher serum level.
Perindopril Perindopril Valaciclovir may decrease the excretion rate of Perindopril which could result in a higher serum level.
Tenofovir Tenofovir Valaciclovir may increase the nephrotoxic activities of Tenofovir.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Eplerenone Eplerenone Eplerenone may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Zonisamide Zonisamide Valaciclovir may decrease the excretion rate of Zonisamide which could result in a higher serum level.
Atomoxetine Atomoxetine Valaciclovir may decrease the excretion rate of Atomoxetine which could result in a higher serum level.
Atazanavir Atazanavir Atazanavir may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Almotriptan Almotriptan Valaciclovir may decrease the excretion rate of Almotriptan which could result in a higher serum level.
Rosuvastatin Rosuvastatin The excretion of Valaciclovir can be decreased when combined with Rosuvastatin.
Emtricitabine Emtricitabine Valaciclovir may decrease the excretion rate of Emtricitabine which could result in a higher serum level.
Memantine Memantine Valaciclovir may decrease the excretion rate of Memantine which could result in a higher serum level.
Tadalafil Tadalafil Valaciclovir may decrease the excretion rate of Tadalafil which could result in a higher serum level.
Duloxetine Duloxetine Valaciclovir may decrease the excretion rate of Duloxetine which could result in a higher serum level.
Tinidazole Tinidazole Valaciclovir may decrease the excretion rate of Tinidazole which could result in a higher serum level.
Cefditoren Cefditoren Valaciclovir may decrease the excretion rate of Cefdinir which could result in a higher serum level.
Cyanocobalamin Injection Cyanocobalamin Injection Valaciclovir may decrease the excretion rate of Hydroxocobalamin which could result in a higher serum level.
Eszopiclone Eszopiclone Valaciclovir may decrease the excretion rate of Eszopiclone which could result in a higher serum level.
Ganciclovir Ganciclovir Valaciclovir may decrease the excretion rate of Ganciclovir which could result in a higher serum level.
Ribavirin Ribavirin Valaciclovir may decrease the excretion rate of Ribavirin which could result in a higher serum level.
Valganciclovir Valganciclovir Valaciclovir may decrease the excretion rate of Valganciclovir which could result in a higher serum level.
Zoledronic Acid Injection Zoledronic Acid Injection The risk or severity of nephrotoxicity and hypocalcemia can be increased when Valaciclovir is combined with Zoledronic acid.
Adefovir Adefovir Adefovir may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine Valaciclovir may decrease the excretion rate of Amphetamine which could result in a higher serum level.
Ibandronate Ibandronate The risk or severity of nephrotoxicity and hypocalcemia can be increased when Valaciclovir is combined with Ibandronate.
Ramelteon Ramelteon Valaciclovir may decrease the excretion rate of Ramelteon which could result in a higher serum level.
Fentanyl Fentanyl Valaciclovir may decrease the excretion rate of Fentanyl which could result in a higher serum level.
Pregabalin Pregabalin Valaciclovir may decrease the excretion rate of Pregabalin which could result in a higher serum level.
Ranolazine Ranolazine Valaciclovir may decrease the excretion rate of Ranolazine which could result in a higher serum level.
Rasagiline Rasagiline Valaciclovir may decrease the excretion rate of Rasagiline which could result in a higher serum level.
Sitagliptin Sitagliptin Valaciclovir may decrease the excretion rate of Sitagliptin which could result in a higher serum level.
Varenicline Varenicline Valaciclovir may decrease the excretion rate of Varenicline which could result in a higher serum level.
Albuterol Albuterol Valaciclovir may decrease the excretion rate of Salbutamol which could result in a higher serum level.
Paliperidone Paliperidone Valaciclovir may decrease the excretion rate of Paliperidone which could result in a higher serum level.
Clofarabine Injection Clofarabine Injection Valaciclovir may decrease the excretion rate of Clofarabine which could result in a higher serum level.
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Valaciclovir.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The therapeutic efficacy of Varicella Zoster Vaccine (Live/attenuated) can be decreased when used in combination with Valaciclovir.
Lubiprostone Lubiprostone Valaciclovir may decrease the excretion rate of Lubiprostone which could result in a higher serum level.
Pemetrexed Injection Pemetrexed Injection Valaciclovir may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Sorafenib Sorafenib Valaciclovir may decrease the excretion rate of Sorafenib which could result in a higher serum level.
Levocetirizine Levocetirizine Valaciclovir may decrease the excretion rate of Levocetirizine which could result in a higher serum level.
Pegaptanib Injection Pegaptanib Injection Valaciclovir may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
Azacitidine Injection Azacitidine Injection Valaciclovir may decrease the excretion rate of Azacitidine which could result in a higher serum level.
Lenalidomide Lenalidomide Valaciclovir may decrease the excretion rate of Lenalidomide which could result in a higher serum level.
Budesonide Budesonide Valaciclovir may decrease the excretion rate of Budesonide which could result in a higher serum level.
Desmopressin Desmopressin Valaciclovir may decrease the excretion rate of Desmopressin which could result in a higher serum level.
Doripenem Injection Doripenem Injection Valaciclovir may decrease the excretion rate of Doripenem which could result in a higher serum level.
Arsenic Trioxide Injection Arsenic Trioxide Injection Valaciclovir may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level.
Desvenlafaxine Desvenlafaxine Valaciclovir may decrease the excretion rate of Desvenlafaxine which could result in a higher serum level.
Cevimeline Cevimeline Valaciclovir may decrease the excretion rate of Cevimeline which could result in a higher serum level.
Leucovorin Injection Leucovorin Injection The excretion of Valaciclovir can be decreased when combined with Leucovorin.
Certolizumab Injection Certolizumab Injection Valaciclovir may decrease the excretion rate of Certolizumab pegol which could result in a higher serum level.
Daptomycin Injection Daptomycin Injection Valaciclovir may decrease the excretion rate of Daptomycin which could result in a higher serum level.
Methylnaltrexone Injection Methylnaltrexone Injection Valaciclovir may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Midazolam Midazolam Valaciclovir may decrease the excretion rate of Midazolam which could result in a higher serum level.
Dexrazoxane Injection Dexrazoxane Injection Valaciclovir may decrease the excretion rate of Dexrazoxane which could result in a higher serum level.
Milnacipran Milnacipran Valaciclovir may decrease the excretion rate of Milnacipran which could result in a higher serum level.
Plerixafor Injection Plerixafor Injection Valaciclovir may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Fesoterodine Fesoterodine Valaciclovir may decrease the excretion rate of Fesoterodine which could result in a higher serum level.
Prasugrel Prasugrel Valaciclovir may decrease the excretion rate of Prasugrel which could result in a higher serum level.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) Tolvaptan may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Dronedarone Dronedarone The excretion of Valaciclovir can be decreased when combined with Dronedarone.
Pralatrexate Injection Pralatrexate Injection Valaciclovir may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection Valaciclovir may decrease the excretion rate of Palonosetron which could result in a higher serum level.
Saxagliptin Saxagliptin Valaciclovir may decrease the excretion rate of Saxagliptin which could result in a higher serum level.
Telavancin Injection Telavancin Injection Valaciclovir may decrease the excretion rate of Telavancin which could result in a higher serum level.
Topotecan Topotecan Valaciclovir may decrease the excretion rate of Topotecan which could result in a higher serum level.
Dalfampridine Dalfampridine Valaciclovir may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Acetaminophen Injection Acetaminophen Injection Valaciclovir may decrease the excretion rate of Acetaminophen which could result in a higher serum level.
Ipilimumab Injection Ipilimumab Injection Valaciclovir may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection Valaciclovir may decrease the excretion rate of Aldesleukin which could result in a higher serum level.
Terbutaline Injection Terbutaline Injection Valaciclovir may decrease the excretion rate of Terbutaline which could result in a higher serum level.
Roflumilast Roflumilast Valaciclovir may decrease the excretion rate of Roflumilast which could result in a higher serum level.
Rivaroxaban Rivaroxaban Valaciclovir may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Ruxolitinib Ruxolitinib Valaciclovir may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Clobazam Clobazam Valaciclovir may decrease the excretion rate of Clobazam which could result in a higher serum level.
Deferiprone Deferiprone Valaciclovir may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Naloxone Injection Naloxone Injection Valaciclovir may decrease the excretion rate of Naloxone which could result in a higher serum level.
Fondaparinux Injection Fondaparinux Injection Valaciclovir may decrease the excretion rate of Fondaparinux which could result in a higher serum level.
Enzalutamide Enzalutamide Valaciclovir may decrease the excretion rate of Enzalutamide which could result in a higher serum level.
Mirabegron Mirabegron Valaciclovir may decrease the excretion rate of Mirabegron which could result in a higher serum level.
Teriflunomide Teriflunomide The excretion of Valaciclovir can be decreased when combined with Teriflunomide.
Teduglutide Injection Teduglutide Injection Valaciclovir may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Alogliptin Alogliptin Valaciclovir may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Pomalidomide Pomalidomide Valaciclovir may decrease the excretion rate of Pomalidomide which could result in a higher serum level.
Canagliflozin Canagliflozin Valaciclovir may decrease the excretion rate of Canagliflozin which could result in a higher serum level.
Methazolamide Methazolamide Methazolamide may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Dabrafenib Dabrafenib The excretion of Valaciclovir can be decreased when combined with Dabrafenib.
Trametinib Trametinib Valaciclovir may decrease the excretion rate of Trametinib which could result in a higher serum level.
Dolutegravir Dolutegravir The excretion of Valaciclovir can be decreased when combined with Dolutegravir.
Levomilnacipran Levomilnacipran Valaciclovir may decrease the excretion rate of Levomilnacipran which could result in a higher serum level.
Ertapenem Injection Ertapenem Injection Valaciclovir may decrease the excretion rate of Ertapenem which could result in a higher serum level.
Vortioxetine Vortioxetine Valaciclovir may decrease the excretion rate of Vortioxetine which could result in a higher serum level.
Ketorolac Injection Ketorolac Injection Ketorolac may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Sofosbuvir Sofosbuvir Valaciclovir may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin Dapagliflozin may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Apremilast Apremilast Valaciclovir may decrease the excretion rate of Apremilast which could result in a higher serum level.
Droxidopa Droxidopa Valaciclovir may decrease the excretion rate of Droxidopa which could result in a higher serum level.
Testosterone Injection Testosterone Injection Valaciclovir may decrease the excretion rate of Testosterone which could result in a higher serum level.
Edoxaban Edoxaban Valaciclovir may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Methamphetamine Methamphetamine Valaciclovir may decrease the excretion rate of Metamfetamine which could result in a higher serum level.
Tasimelteon Tasimelteon Valaciclovir may decrease the excretion rate of Tasimelteon which could result in a higher serum level.
Lenvatinib Lenvatinib The excretion of Valaciclovir can be decreased when combined with Lenvatinib.
Haloperidol Injection Haloperidol Injection Valaciclovir may decrease the excretion rate of Haloperidol which could result in a higher serum level.
Amiloride Amiloride Amiloride may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Macitentan Macitentan Valaciclovir may decrease the excretion rate of Macitentan which could result in a higher serum level.
Penicillin G Procaine Injection Penicillin G Procaine Injection Valaciclovir may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Ixazomib Ixazomib Valaciclovir may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lesinurad Lesinurad Valaciclovir may decrease the excretion rate of Lesinurad which could result in a higher serum level.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Brivaracetam Injection Brivaracetam Injection Valaciclovir may decrease the excretion rate of Brivaracetam which could result in a higher serum level.
Furosemide Injection Furosemide Injection Valaciclovir may decrease the excretion rate of Furosemide which could result in a higher serum level.
Rucaparib Rucaparib The excretion of Valaciclovir can be decreased when combined with Rucaparib.
Lixisenatide Injection Lixisenatide Injection Valaciclovir may decrease the excretion rate of Lixisenatide which could result in a higher serum level.
Doxepin (Insomnia) Doxepin (Insomnia) Valaciclovir may decrease the excretion rate of Doxepin which could result in a higher serum level.
Deutetrabenazine Deutetrabenazine Valaciclovir may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level.
Valbenazine Valbenazine Valaciclovir may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Naldemedine Naldemedine Valaciclovir may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Enasidenib Enasidenib The excretion of Valaciclovir can be decreased when combined with Enasidenib.
Benznidazole Benznidazole Valaciclovir may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Delafloxacin Delafloxacin Valaciclovir may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Letermovir Letermovir The excretion of Valaciclovir can be decreased when combined with Letermovir.
Ertugliflozin Ertugliflozin Ertugliflozin may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Apalutamide Apalutamide Valaciclovir may decrease the excretion rate of Apalutamide which could result in a higher serum level.
Avatrombopag Avatrombopag The excretion of Valaciclovir can be decreased when combined with Avatrombopag.
Baricitinib Baricitinib Valaciclovir may decrease the excretion rate of Baricitinib which could result in a higher serum level.
Lofexidine Lofexidine Valaciclovir may decrease the excretion rate of Lofexidine which could result in a higher serum level.
Plazomicin Injection Plazomicin Injection Valaciclovir may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Ivosidenib Ivosidenib The excretion of Valaciclovir can be decreased when combined with Ivosidenib.
Stiripentol Stiripentol Valaciclovir may decrease the excretion rate of Stiripentol which could result in a higher serum level.
Prucalopride Prucalopride Valaciclovir may decrease the excretion rate of Prucalopride which could result in a higher serum level.
Acyclovir Ophthalmic Acyclovir Ophthalmic Valaciclovir may decrease the excretion rate of Acyclovir which could result in a higher serum level.
Esomeprazole Injection Esomeprazole Injection The excretion of Valaciclovir can be decreased when combined with Esomeprazole.
Solriamfetol Solriamfetol Valaciclovir may decrease the excretion rate of Solriamfetol which could result in a higher serum level.
Pitolisant Pitolisant Valaciclovir may decrease the excretion rate of Pitolisant which could result in a higher serum level.
Cabotegravir Cabotegravir The excretion of Valaciclovir can be decreased when combined with Cabotegravir.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives Drospirenone may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Viloxazine Viloxazine Valaciclovir may decrease the excretion rate of Viloxazine which could result in a higher serum level.
Tobramycin Injection Tobramycin Injection Tobramycin may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Fenoprofen Fenoprofen Fenoprofen may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Indomethacin Indomethacin Indomethacin may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Mefenamic Acid Mefenamic Acid Mefenamic acid may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Naproxen Naproxen Naproxen may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Tolmetin Tolmetin Tolmetin may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Sulindac Sulindac Sulindac may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Isotretinoin Isotretinoin Valaciclovir may decrease the excretion rate of Isotretinoin which could result in a higher serum level.
Sucralfate Sucralfate Valaciclovir may decrease the excretion rate of Sucralfate which could result in a higher serum level.
Floxuridine Floxuridine Valaciclovir may decrease the excretion rate of Floxuridine which could result in a higher serum level.
Metaxalone Metaxalone Valaciclovir may decrease the excretion rate of Metaxalone which could result in a higher serum level.
Methotrexate Injection Methotrexate Injection Methotrexate may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Chlorpromazine Chlorpromazine Valaciclovir may decrease the excretion rate of Chlorpromazine which could result in a higher serum level.
Diazepam Diazepam Valaciclovir may decrease the excretion rate of Diazepam which could result in a higher serum level.
Oxazepam Oxazepam Valaciclovir may decrease the excretion rate of Oxazepam which could result in a higher serum level.
Flurazepam Flurazepam Valaciclovir may decrease the excretion rate of Flurazepam which could result in a higher serum level.
Clorazepate Clorazepate Valaciclovir may decrease the excretion rate of Clorazepic acid which could result in a higher serum level.
Lorazepam Lorazepam Valaciclovir may decrease the excretion rate of Lorazepam which could result in a higher serum level.
Carmustine Carmustine Valaciclovir may decrease the excretion rate of Carmustine which could result in a higher serum level.
Amantadine Amantadine Valaciclovir may decrease the excretion rate of Amantadine which could result in a higher serum level.
Codeine Codeine Valaciclovir may decrease the excretion rate of Codeine which could result in a higher serum level.
Phenelzine Phenelzine Valaciclovir may decrease the excretion rate of Phenelzine which could result in a higher serum level.
Tetracycline Tetracycline Valaciclovir may decrease the excretion rate of Tetracycline which could result in a higher serum level.
Minocycline Minocycline The excretion of Valaciclovir can be decreased when combined with Minocycline.
Bleomycin Bleomycin Valaciclovir may decrease the excretion rate of Bleomycin which could result in a higher serum level.
Sulfadiazine Sulfadiazine Valaciclovir may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Methadone Methadone Valaciclovir may decrease the excretion rate of Methadone which could result in a higher serum level.
Benztropine Benztropine Valaciclovir may decrease the excretion rate of Benzatropine which could result in a higher serum level.
Maprotiline Maprotiline Valaciclovir may decrease the excretion rate of Maprotiline which could result in a higher serum level.
Ibuprofen Ibuprofen Valaciclovir may decrease the excretion rate of Ibuprofen which could result in a higher serum level.
Azathioprine Azathioprine Valaciclovir may decrease the excretion rate of Azathioprine which could result in a higher serum level.
Methylphenidate Methylphenidate Valaciclovir may decrease the excretion rate of Methylphenidate which could result in a higher serum level.
Sulfasalazine Sulfasalazine Sulfasalazine may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Phenazopyridine Phenazopyridine The risk or severity of nephrotoxicity can be increased when Valaciclovir is combined with Phenazopyridine.
Carbamazepine Carbamazepine Valaciclovir may decrease the excretion rate of Carbamazepine which could result in a higher serum level.
Methyldopa Methyldopa Valaciclovir may decrease the excretion rate of Methyldopa which could result in a higher serum level.
Hydralazine Hydralazine Valaciclovir may decrease the excretion rate of Hydralazine which could result in a higher serum level.
Cimetidine Cimetidine Valaciclovir may decrease the excretion rate of Cimetidine which could result in a higher serum level.
Gentamicin Injection Gentamicin Injection Gentamicin may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Warfarin Warfarin Valaciclovir may decrease the excretion rate of Warfarin which could result in a higher serum level.
Clonazepam Clonazepam Valaciclovir may decrease the excretion rate of Clonazepam which could result in a higher serum level.
Promethazine Promethazine Valaciclovir may decrease the excretion rate of Promethazine which could result in a higher serum level.
Meclofenamate Meclofenamate Valaciclovir may decrease the excretion rate of Meclofenamic acid which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Valaciclovir may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Digoxin Digoxin Valaciclovir may decrease the excretion rate of Digoxin which could result in a higher serum level.
Chloroquine Chloroquine Valaciclovir may decrease the excretion rate of Chloroquine which could result in a higher serum level.
Triamterene Triamterene The risk or severity of nephrotoxicity can be increased when Triamterene is combined with Valaciclovir.
Chlorothiazide Chlorothiazide Chlorothiazide may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Chlorthalidone Chlorthalidone Chlorthalidone may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Metolazone Metolazone Valaciclovir may decrease the excretion rate of Metolazone which could result in a higher serum level.
Isosorbide Isosorbide Isosorbide may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Secobarbital Secobarbital Valaciclovir may decrease the excretion rate of Secobarbital which could result in a higher serum level.
Desipramine Desipramine Valaciclovir may decrease the excretion rate of Desipramine which could result in a higher serum level.
Amitriptyline Amitriptyline Valaciclovir may decrease the excretion rate of Amitriptyline which could result in a higher serum level.
Imipramine Imipramine Valaciclovir may decrease the excretion rate of Imipramine which could result in a higher serum level.
Probenecid Probenecid Valaciclovir may decrease the excretion rate of Probenecid which could result in a higher serum level.
Quinidine Quinidine Valaciclovir may decrease the excretion rate of Quinidine which could result in a higher serum level.
Procainamide Procainamide Valaciclovir may decrease the excretion rate of Procainamide which could result in a higher serum level.
Isoniazid Isoniazid Valaciclovir may decrease the excretion rate of Isoniazid which could result in a higher serum level.
Pyrazinamide Pyrazinamide Valaciclovir may decrease the excretion rate of Pyrazinamide which could result in a higher serum level.
Rifampin Rifampin The excretion of Valaciclovir can be decreased when combined with Rifampicin.
Disopyramide Disopyramide Valaciclovir may decrease the excretion rate of Disopyramide which could result in a higher serum level.
Valproic Acid Valproic Acid The excretion of Valaciclovir can be decreased when combined with Valproic acid.
Butabarbital Butabarbital Valaciclovir may decrease the excretion rate of Butabarbital which could result in a higher serum level.
Liothyronine Liothyronine Valaciclovir may decrease the excretion rate of Liothyronine which could result in a higher serum level.
Methimazole Methimazole Valaciclovir may decrease the excretion rate of Methimazole which could result in a higher serum level.
Chlorpropamide Chlorpropamide Valaciclovir may decrease the excretion rate of Chlorpropamide which could result in a higher serum level.
Tolbutamide Tolbutamide Valaciclovir may decrease the excretion rate of Tolbutamide which could result in a higher serum level.
Tolazamide Tolazamide Valaciclovir may decrease the excretion rate of Tolazamide which could result in a higher serum level.
Dinoprostone Dinoprostone The excretion of Valaciclovir can be decreased when combined with Dinoprostone.
Baclofen Baclofen Valaciclovir may decrease the excretion rate of Baclofen which could result in a higher serum level.
Ethambutol Ethambutol Valaciclovir may decrease the excretion rate of Ethambutol which could result in a higher serum level.
Methyclothiazide Methyclothiazide Methyclothiazide may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of nephrotoxicity can be increased when Valaciclovir is combined with Hydrochlorothiazide.
Chlorzoxazone Chlorzoxazone Valaciclovir may decrease the excretion rate of Chlorzoxazone which could result in a higher serum level.
Pyridoxine Pyridoxine Valaciclovir may decrease the excretion rate of Pyridoxine which could result in a higher serum level.
Folic Acid Folic Acid Valaciclovir may decrease the excretion rate of Folic acid which could result in a higher serum level.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) Valaciclovir may decrease the excretion rate of Propranolol which could result in a higher serum level.
Spironolactone Spironolactone Spironolactone may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Injection Amphotericin B Injection Amphotericin B may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Mercaptopurine Mercaptopurine The excretion of Valaciclovir can be decreased when combined with Mercaptopurine.
Phytonadione Phytonadione Valaciclovir may decrease the excretion rate of Phylloquinone which could result in a higher serum level.
Amikacin Injection Amikacin Injection Amikacin may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Nadolol Nadolol Valaciclovir may decrease the excretion rate of Nadolol which could result in a higher serum level.
Allopurinol Allopurinol Valaciclovir may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Flavoxate Flavoxate Valaciclovir may decrease the excretion rate of Flavoxate which could result in a higher serum level.
Colchicine Colchicine Valaciclovir may decrease the excretion rate of Colchicine which could result in a higher serum level.
Cefaclor Cefaclor Valaciclovir may decrease the excretion rate of Cefaclor which could result in a higher serum level.
Cefadroxil Cefadroxil Valaciclovir may decrease the excretion rate of Cefadroxil which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Cephalexin Cephalexin Cephalexin may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Dacarbazine Dacarbazine Valaciclovir may decrease the excretion rate of Dacarbazine which could result in a higher serum level.
Acetazolamide Acetazolamide Acetazolamide may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection Valaciclovir may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The therapeutic efficacy of Bacillus calmette-guerin substrain tice live antigen can be decreased when used in combination with Valaciclovir.
Pyrantel Pyrantel Valaciclovir may decrease the excretion rate of Pyrantel which could result in a higher serum level.
Ethacrynic Acid Ethacrynic Acid The risk or severity of nephrotoxicity can be increased when Valaciclovir is combined with Etacrynic acid.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Metoprolol Metoprolol Valaciclovir may decrease the excretion rate of Metoprolol which could result in a higher serum level.
Aspirin Aspirin Valaciclovir may decrease the excretion rate of Acetylsalicylic acid which could result in a higher serum level.
Salsalate Salsalate Salsalate may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Alprazolam Alprazolam Valaciclovir may decrease the excretion rate of Alprazolam which could result in a higher serum level.
Temazepam Temazepam Valaciclovir may decrease the excretion rate of Temazepam which could result in a higher serum level.
Triazolam Triazolam Valaciclovir may decrease the excretion rate of Triazolam which could result in a higher serum level.
Dicyclomine Dicyclomine Valaciclovir may decrease the excretion rate of Dicyclomine which could result in a higher serum level.
Propantheline Propantheline Valaciclovir may decrease the excretion rate of Propantheline which could result in a higher serum level.
Trimethoprim Trimethoprim Valaciclovir may decrease the excretion rate of Trimethoprim which could result in a higher serum level.
Nifedipine Nifedipine Valaciclovir may decrease the excretion rate of Nifedipine which could result in a higher serum level.
Timolol Timolol Valaciclovir may decrease the excretion rate of Timolol which could result in a higher serum level.
Verapamil Verapamil Valaciclovir may decrease the excretion rate of Verapamil which could result in a higher serum level.
Pindolol Pindolol Valaciclovir may decrease the excretion rate of Pindolol which could result in a higher serum level.
Cisplatin Injection Cisplatin Injection Valaciclovir may decrease the excretion rate of Cisplatin which could result in a higher serum level.
Diflunisal Diflunisal Valaciclovir may decrease the excretion rate of Diflunisal which could result in a higher serum level.
Piroxicam Piroxicam Piroxicam may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Bumetanide Bumetanide Valaciclovir may decrease the excretion rate of Bumetanide which could result in a higher serum level.
Glipizide Glipizide Valaciclovir may decrease the excretion rate of Glipizide which could result in a higher serum level.
Indapamide Indapamide Valaciclovir may decrease the excretion rate of Indapamide which could result in a higher serum level.
Amoxicillin Amoxicillin Valaciclovir may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
Oxacillin Injection Oxacillin Injection Valaciclovir may decrease the excretion rate of Oxacillin which could result in a higher serum level.
Pentoxifylline Pentoxifylline Valaciclovir may decrease the excretion rate of Pentoxifylline which could result in a higher serum level.
Pentamidine Injection Pentamidine Injection Pentamidine may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Ceftriaxone Injection Ceftriaxone Injection Valaciclovir may decrease the excretion rate of Ceftriaxone which could result in a higher serum level.
Labetalol Labetalol Valaciclovir may decrease the excretion rate of Labetalol which could result in a higher serum level.
Auranofin Auranofin Valaciclovir may decrease the excretion rate of Auranofin which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection Valaciclovir may decrease the excretion rate of Leuprolide which could result in a higher serum level.
Gemfibrozil Gemfibrozil Valaciclovir may decrease the excretion rate of Gemfibrozil which could result in a higher serum level.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Ketoprofen Ketoprofen Valaciclovir may decrease the excretion rate of Ketoprofen which could result in a higher serum level.
Cefotetan Injection Cefotetan Injection Valaciclovir may decrease the excretion rate of Cefotetan which could result in a higher serum level.
Enalapril Enalapril The excretion of Valaciclovir can be decreased when combined with Enalapril.
Flurbiprofen Flurbiprofen Valaciclovir may decrease the excretion rate of Flurbiprofen which could result in a higher serum level.
Aztreonam Injection Aztreonam Injection Valaciclovir may decrease the excretion rate of Aztreonam which could result in a higher serum level.
Buspirone Buspirone Valaciclovir may decrease the excretion rate of Buspirone which could result in a higher serum level.
Ciprofloxacin Ciprofloxacin Valaciclovir may decrease the excretion rate of Ciprofloxacin which could result in a higher serum level.
Mesalamine Mesalamine Mesalazine may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Diclofenac Diclofenac Diclofenac may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Clozapine Clozapine Valaciclovir may decrease the excretion rate of Clozapine which could result in a higher serum level.
Estazolam Estazolam Valaciclovir may decrease the excretion rate of Estazolam which could result in a higher serum level.
Didanosine Didanosine Valaciclovir may decrease the excretion rate of Didanosine which could result in a higher serum level.
Pentostatin Injection Pentostatin Injection Valaciclovir may decrease the excretion rate of Pentostatin which could result in a higher serum level.
Etodolac Etodolac Valaciclovir may decrease the excretion rate of Etodolac which could result in a higher serum level.
Fosinopril Fosinopril Valaciclovir may decrease the excretion rate of Fosinopril which could result in a higher serum level.
Nabumetone Nabumetone Nabumetone may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Pravastatin Pravastatin The excretion of Valaciclovir can be decreased when combined with Pravastatin.
Lisinopril Lisinopril Valaciclovir may decrease the excretion rate of Lisinopril which could result in a higher serum level.
Oxaprozin Oxaprozin Valaciclovir may decrease the excretion rate of Oxaprozin which could result in a higher serum level.
Bisoprolol Bisoprolol Valaciclovir may decrease the excretion rate of Bisoprolol which could result in a higher serum level.
Isradipine Isradipine Valaciclovir may decrease the excretion rate of Isradipine which could result in a higher serum level.
Venlafaxine Venlafaxine Valaciclovir may decrease the excretion rate of Venlafaxine which could result in a higher serum level.
Fluvoxamine Fluvoxamine Valaciclovir may decrease the excretion rate of Fluvoxamine which could result in a higher serum level.
Nefazodone Nefazodone Valaciclovir may decrease the excretion rate of Nefazodone which could result in a higher serum level.
Lamotrigine Lamotrigine Valaciclovir may decrease the excretion rate of Lamotrigine which could result in a higher serum level.
Tramadol Tramadol Valaciclovir may decrease the excretion rate of Tramadol which could result in a higher serum level.
Carboplatin Injection Carboplatin Injection Valaciclovir may decrease the excretion rate of Carboplatin which could result in a higher serum level.
Lansoprazole Lansoprazole The excretion of Valaciclovir can be decreased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection Valaciclovir may decrease the excretion rate of Ifosfamide which could result in a higher serum level.
Bupropion Bupropion Valaciclovir may decrease the excretion rate of Bupropion which could result in a higher serum level.
Ticlopidine Ticlopidine Valaciclovir may decrease the excretion rate of Ticlopidine which could result in a higher serum level.
Metformin Metformin Valaciclovir may decrease the excretion rate of Metformin which could result in a higher serum level.
Nisoldipine Nisoldipine Valaciclovir may decrease the excretion rate of Nisoldipine which could result in a higher serum level.
Lamivudine Lamivudine Valaciclovir may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Acarbose Acarbose Valaciclovir may decrease the excretion rate of Acarbose which could result in a higher serum level.
Gemcitabine Injection Gemcitabine Injection Valaciclovir may decrease the excretion rate of Gemcitabine which could result in a higher serum level.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Meropenem Injection Meropenem Injection Valaciclovir may decrease the excretion rate of Meropenem which could result in a higher serum level.
Clomipramine Clomipramine Valaciclovir may decrease the excretion rate of Clomipramine which could result in a higher serum level.
Fosfomycin Fosfomycin Valaciclovir may decrease the excretion rate of Fosfomycin which could result in a higher serum level.
Topiramate Topiramate Valaciclovir may decrease the excretion rate of Topiramate which could result in a higher serum level.
Pramipexole Pramipexole Valaciclovir may decrease the excretion rate of Pramipexole which could result in a higher serum level.
Nilutamide Nilutamide Valaciclovir may decrease the excretion rate of Nilutamide which could result in a higher serum level.
Flutamide Flutamide Valaciclovir may decrease the excretion rate of Flutamide which could result in a higher serum level.
Tamsulosin Tamsulosin Valaciclovir may decrease the excretion rate of Tamsulosin which could result in a higher serum level.
Quetiapine Quetiapine Valaciclovir may decrease the excretion rate of Quetiapine which could result in a higher serum level.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Cetirizine Cetirizine Valaciclovir may decrease the excretion rate of Cetirizine which could result in a higher serum level.
Tolcapone Tolcapone Valaciclovir may decrease the excretion rate of Tolcapone which could result in a higher serum level.
Capecitabine Capecitabine Valaciclovir may decrease the excretion rate of Capecitabine which could result in a higher serum level.
Abacavir Abacavir Valaciclovir may decrease the excretion rate of Abacavir which could result in a higher serum level.
Celecoxib Celecoxib Celecoxib may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Rosiglitazone Rosiglitazone Valaciclovir may decrease the excretion rate of Rosiglitazone which could result in a higher serum level.
Tolterodine Tolterodine Valaciclovir may decrease the excretion rate of Tolterodine which could result in a higher serum level.
Oseltamivir Oseltamivir Valaciclovir may decrease the excretion rate of Oseltamivir which could result in a higher serum level.
Balsalazide Balsalazide Balsalazide may decrease the excretion rate of Valaciclovir which could result in a higher serum level.
Nateglinide Nateglinide Valaciclovir may decrease the excretion rate of Nateglinide which could result in a higher serum level.
Rabeprazole Rabeprazole Valaciclovir may decrease the excretion rate of Rabeprazole which could result in a higher serum level.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists