Vancomycin Hydrochloride Injection shortage
Vancomycin Hydrochloride Injection is currently listed in shortage by the FDA. The FDA lists 1 affected product. This page was last refreshed from FDA data on Sep 22, 2026.
Pfizer (Hospira) is permanently stopping production of the NovaPlus vancomycin hydrochloride 10 g injection vial. Other strengths of vancomycin hydrochloride injection are still listed as available from Hikma and Hospira.
Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Vancomycin Hydrochloride Injection. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
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Nov 14, 2025Currently in shortage1 of 1 product affected.
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Nov 14, 2025First reported to the FDA1 product first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: Hospira, Inc., a Pfizer Company 📞 844-646-4398 1 NDC click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| To Be Discontinued | Vancomycin Hydrochloride, Injection, 10 g Vial NovaPlus (NDC 0409-5017-01) | — | — | Discontinuation of the manufacture of the drug | — |
These rows are manufacturer reports to the FDA for Vancomycin Hydrochloride Injection — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Vancomycin Hydrochloride Injection? options further down this page.
Why is Vancomycin Hydrochloride Injection in shortage?
Hospira (a Pfizer company) has reported to the FDA that they are permanently stopping the manufacture of one specific version of vancomycin hydrochloride injection — the 10 g vial sold under the NovaPlus label (NDC 0409-5017-01). That's why this particular product appears on the shortage list.
No specific reason was shared publicly for why Hospira made this decision — the FDA filing simply states it's a discontinuation of manufacturing for this product. It's worth knowing that this applies only to this one specific package and size from Hospira/Pfizer. It does not necessarily mean vancomycin injection as a whole is going away, as other manufacturers and presentations may not be affected by this decision.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Vancomycin Hydrochloride Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Vancomycin Hydrochloride Injection?
Vancomycin Hydrochloride Injection is currently on the FDA shortage list, and I want to walk you through what that means for you.
The specific product affected is the 10 g Vial (NovaPlus) made by Hospira, Inc., a Pfizer Company. This strength has no available source reported right now, and the maker has listed it as being discontinued. In practice, that means this particular supply problem may be permanent rather than a short-term gap. No other strengths are covered by this specific record.
Because this is a discontinuation, the most important next step is a conversation with your prescriber or pharmacist. Here is how I would approach it:
- Do not stop, skip, or change how you use this medicine on your own.
- Ask your pharmacy to check with wholesalers, since local stock can differ from national reports.
- The same medicine, vancomycin, is still made in several strengths by other manufacturers, including Hikma Pharmaceuticals and Hospira. Your pharmacy may be able to source one of these, though it may not be in local stock and a prescriber's guidance is needed to match your dose.
- Ask your prescriber or pharmacist about a suitable option if this exact vial cannot be found.
Manufacturer contact numbers are listed on this page for reference, though pharmacies usually handle those calls. This is general, national information and may not match your pharmacy's actual stock.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.
Where else can I get Vancomycin Hydrochloride Injection?
FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Vancomycin Hydrochloride Injection is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.
Same medicine, other manufacturers (not reported short)
Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:
| Product | Strength | Form / route | Manufacturer | NDC |
|---|---|---|---|---|
| Vancomycin Hydrochloride | VANCOMYCIN HYDROCHLORIDE 1.25 g/1 | Injection, Powder, Lyophilized, For Solution · Intravenous | Hikma Pharmaceuticals USA Inc. | 00143-9152-10 |
| Vancomycin Hydrochloride | VANCOMYCIN HYDROCHLORIDE 1.5 g/1 | Injection, Powder, Lyophilized, For Solution · Intravenous | Hikma Pharmaceuticals USA Inc. | 00143-9153-10 |
| Vancomycin Hydrochloride | VANCOMYCIN 750 mg/1 | Injection, Powder, Lyophilized, For Solution · Intravenous | Hikma Pharmaceuticals USA Inc. | 00143-9355-10 |
| Vancomycin Hydrochloride | VANCOMYCIN HYDROCHLORIDE 1 g/1 | Injection, Powder, Lyophilized, For Solution · Intravenous | Hikma Pharmaceuticals USA Inc. | 00143-9357-10 |
| Vancomycin Hydrochloride | VANCOMYCIN HYDROCHLORIDE 5 g/1 | Injection, Powder, For Solution · Intravenous | Hikma Pharmaceuticals USA Inc. | 00143-9358-01 |
| Vancomycin Hydrochloride | VANCOMYCIN HYDROCHLORIDE 10 g/1 | Injection, Powder, For Solution · Intravenous | Hikma Pharmaceuticals USA Inc. | 00143-9359-01 |
| Vancomycin Hydrochloride | VANCOMYCIN HYDROCHLORIDE 500 mg/5mL | Injection, Powder, Lyophilized, For Solution · Intravenous | Hospira, Inc. | 00409-1319-01 |
| Vancomycin Hydrochloride | VANCOMYCIN HYDROCHLORIDE 1.5 g/1 | Injection, Powder, Lyophilized, For Solution · Intravenous | Hospira, Inc. | 00409-3515-01 |
| Vancomycin Hydrochloride | VANCOMYCIN HYDROCHLORIDE 500 mg/1 | Injection, Powder, Lyophilized, For Solution · Intravenous | Hospira, Inc. | 00409-4332-01 |
| Vancomycin Hydrochloride | VANCOMYCIN HYDROCHLORIDE 500 mg/10mL | Injection, Powder, Lyophilized, For Solution · Intravenous | Hospira, Inc. | 00409-6509-01 |
| Vancomycin Hydrochloride | VANCOMYCIN HYDROCHLORIDE 750 mg/1 | Injection, Powder, Lyophilized, For Solution · Intravenous | Hospira, Inc. | 00409-6531-01 |
| Vancomycin Hydrochloride | VANCOMYCIN HYDROCHLORIDE 1 g/1 | Injection, Powder, Lyophilized, For Solution · Intravenous | Hospira, Inc. | 00409-6533-21 |
Alternative dosage forms of Vancomycin Hydrochloride
A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:
Therapeutic equivalents & pricing 15 productsclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| Vancomycin Hydrochloride 5.13 g/g | HIKMA | 1 vial | — | — | FDA listed |
| Vancomycin Hydrochloride 10.25 g/g | HIKMA | 1 vial | — | — | FDA listed |
| Vancomycin Hydrochloride 10 g | Hikma | 1 injection | — | AP | FDA listed |
| Vancomycin Hydrochloride 500 mg/5mL | Hospira, | 1 vial | — | AP | FDA listed |
| Vancomycin Hydrochloride 500 mg/5mL | Hospira, | 1 vial | — | AP | Discontinued |
| Vancomycin 10 g/100mL | Sagent | 1 bottle | — | AP | FDA listed |
| Vancomycin Hydrochloride 10 g | Eugia | 1 vial | — | AP | FDA listed |
| Vancomycin Hydrochloride 10 g/100mL | Fresenius | 1 bottle | — | AP | FDA listed |
| Vancomycin Hydrochloride 100 g | SAMSON | 1 injection | — | — | FDA listed |
| Vancomycin Hydrochloride 10 g/100mL | Mylan | 1 vial | — | AP | FDA listed |
| Vancomycin Hydrochloride 10 g | BluePoint | 1 vial | — | AP | FDA listed |
| Vancomycin Hydrochloride 10 g/100mL | Gland | 1 bottle | — | AP | FDA listed |
| Vancomycin Hydrochloride 10 g | Slate | 1 vial | — | AP | FDA listed |
| Vancomycin Hydrochloride 10 g/95mL | Meitheal | 1 vial | — | AP | FDA listed |
| Vancomycin Hydrochloride 500 mg/5mL | Civica, | 1 vial | — | AP | FDA listed |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Vancomycin Hydrochloride Injection — that fall in the same broad treatment class (vancomycin antibiotics and derivatives) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Identity & classification
Where does this data come from?
Other anti-infective shortages
Vancomycin Hydrochloride Injection shortage FAQs
Is Vancomycin Hydrochloride Injection in shortage?
Which products are affected?
When will Vancomycin Hydrochloride Injection be available again?
Can I still get Vancomycin Hydrochloride somewhere?
What should I do if I take Vancomycin Hydrochloride Injection?
Still have a question about the Vancomycin Hydrochloride Injection shortage?
Ask a pharmacist about this shortage →View Vancomycin Hydrochloride Injection on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.