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Rifadin (Rifampin) Injection shortage

Rifadin (and its generic, rifampin injections) is on the FDA’s drug shortage list as of Oct 8, 2026. Brand-name Rifadin is short too: Sanofi-Aventis U.S. says 1 of its 2 Rifadin products is unavailable and 1 is being discontinued. The companies reporting it blame a company discontinuing its product and rising demand.

Current ⚠ Supply risk: High Anti-Infective 4 products 3 companies reporting 2,059 days · 5.6 yr First posted Feb 17, 2021 Updated Oct 6, 2026
Here’s the bottom line

Rifadin (rifampin) injection is in a lasting shortage, driven mainly by generic supply problems — the brand's maker, Sanofi-Aventis, is permanently discontinuing it, while generic versions remain mostly unavailable. The 600 mg vial has one limited source, but the 600 mg/10 mL concentration has no listed supply from any reporting manufacturer.

Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).

Do you take this medicine? See the ‘What to do’ note from Dr. Brian Staiger, PharmD →
4
Affected NDCs
1/3
Reporting makers with supply
1/2
Affected strengths still listed
2,059
Days on the list
64
Medicaid Rx (2025)
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Oct 8, 2026 · today

Is Rifadin still in shortage? — status as of Oct 8, 2026

Yes, still current as of Oct 8, 2026. 1 of the 2 strengths is still made by at least one company; 1 is not. 1 of the 3 companies that reported this shortage says it still has some supply, and we could not find another company that sells it. Your pharmacy may still need to order it.

⚠ Supply risk: High 4 of 5 risk factors
  1. Every strength is still listed by a company — 1 of 2 strengths
  2. More than one company still lists it — 1 of 3 reporting companies with supply
  3. Most affected NDCs still available — 67% unavailable
  4. Not a long-running shortage — 2,059 days
  5. Listed by several companies — 3 companies (3 reporting)

A rule-based estimate of national supply risk, counting both the companies reporting the shortage and the companies listing the same medicine without a report — never your local pharmacy’s stock. How the rating works.

The charts count only the companies that reported this shortage to the FDA; companies that haven’t reported a problem are in the green card, and the Supply-Risk rating counts them too.

Availability of affected NDCs
From the FDA shortage report
4 NDCs
Limited 1 Unavailable 2 To be discontinued 1
Affected strengths still listed by a company
A company on the shortage report with supply, or another company selling that strength
1/2 strengths
Still made by a company 1 No company found making it 1
Reporting companies with supply
Among the 3 companies that reported this shortage
1/3 reporting
Reporting supply 1 Reporting no supply 2
✓ Other companies listing the same medicine — not reporting a shortage
Rifampin Injection listings in the current FDA NDC Directory from companies that have not filed a shortage report — these are not counted in the charts above. Some are repackagers of another company’s product. Stock can still vary by pharmacy.
Plus 6 other dosage forms of rifampin.
See all other options & details →
Shortage timeline
  1. Oct 6, 2026
    Currently in shortage
    4 of 4 products affected.
  2. Oct 5, 2026
    FDA refreshed this shortage record
    1 product updated.
  3. Sep 18, 2026
    FDA refreshed this shortage record
    1 product updated.
  4. Apr 20, 2026
    FDA refreshed this shortage record
    1 product updated.
  5. Apr 20, 2026
    More presentations reported
    1 more product added to the shortage.
  6. Feb 17, 2021
    First reported to the FDA
    3 products first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

Which Rifadin products are affected — by company

Company: Fresenius Kabi USA, LLC 📞 888-386-1300 1 NDC click to expand
Status NDC / product Strength Availability Related information Reason
Current Rifampin Injection, 600 mg NDC 63323-0351-20 600 mg Limited Availability Check wholesalers for inventory Other
Company: Mylan Institutional, a Viatris Company 📞 800-796-9526 1 NDC click to expand
Status NDC / product Strength Availability Related information Reason
Current Rifampin Injection, 600 mg NDC 67457-0445-60 600 mg Unavailable Estimated recovery: Q4 2026 Demand increase for the drug
Company: Sanofi-Aventis U.S. LLC 📞 800-633-1610 2 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Rifadin Injection, 600 mg NDC 00068-0597-01 600 mg Unavailable Discontinuation of the manufacture of the drug Discontinuation of the manufacture of the drug
To Be Discontinued Rifadin Injection, 600 mg/10 mL NDC 00068-0597-01 600 mg/10 mL — Discontinuation of the manufacture of the drug —

These rows are company reports to the FDA for Rifampin Injection — they do not cover every company that lists this medicine. A company appears here only if it told the FDA it has a supply problem, so other companies may still have stock. That’s the basis for the Where else can I get Rifadin or its generic? options further down this page.

Why is Rifadin in shortage?

A note from Dr. Brian Staiger, PharmD · Written Oct 6, 2026

Rifampin injection 600 mg is in short supply right now for a few different reasons depending on the manufacturer. Mylan (a Viatris company) says they can't supply their 600 mg vials right now because more people need this medication than they can currently produce — they expect to have it available again sometime in the fourth quarter of 2026. Fresenius Kabi is still making their 600 mg version, but supply is limited, so availability may vary depending on where you look.

Sanofi-Aventis has permanently stopped making their brand-name version, Rifadin injection 600 mg/10 mL — meaning that specific product won't be coming back from that company. Again, this report only covers these three manufacturers specifically, so supply from other makers may be a separate situation entirely.

FDA reason code(s): Other; Discontinuation of the manufacture of the drug; Demand increase for the drug

Based on the company-reported reason(s) and notes on file with the FDA for Rifampin Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as companies report changes.

What should I do if I take Rifadin?

A note from Dr. Brian Staiger, PharmD · Written Oct 6, 2026

Rifampin Injection is currently on the FDA shortage list, and I want to walk you through what that means for the version you take.

Here is how the strengths break down. The 600 mg strength still has an available source — one manufacturer (Fresenius Kabi) reports limited availability and suggests checking wholesalers for inventory. The 600 mg/10 mL strength currently has no listed source, as the manufacturer that made it reports it is being discontinued. So if you take the 600 mg, supply exists; if you take the 600 mg/10 mL, that specific product may be gone for good.

The reasons on file include increased demand, a discontinuation by one maker, and "other." This shortage has lasted over a year, and one 600 mg supplier estimates recovery around late 2026. Note this affects the generic injection most; the Rifadin brand's 600 mg/10 mL is the discontinued item.

Please do not stop or change your doses on your own. Then consider these steps:

  • If you take the 600 mg, ask your pharmacy to order it — they can check wholesalers and other makers.
  • If your strength is discontinued or can't be found, ask your prescriber or pharmacist about options.
  • Manufacturer contact numbers are listed on this page for reference; pharmacies usually handle those calls.

This is national, manufacturer-reported data and may not match your local pharmacy's actual stock.

See “Where else can I get Rifadin or its generic?” below ↓ The same medicine from companies not reporting a shortage, other dosage forms, and therapeutic equivalents with pricing.
Quick checklist for the pharmacy counter:
  • Ask your pharmacy to check other companies’ versions, other strengths, package sizes, and nearby stores — the options below are a starting point.
  • If this is part of an ongoing or essential regimen (for example HIV, seizure, heart, transplant, diabetes or mental-health medicines), arrange continued supply before you run out rather than rationing doses.
Keep reading
Our full Rifampin guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Rifampin guide →

Where else can I get Rifadin or its generic?

FDA shortages are company-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every company that lists rifampin injections is necessarily short. Below are the other listings in the current FDA NDC Directory that are not reported in shortage: the same medicine from companies that haven’t reported a problem (the reporting companies are excluded), and other dosage forms. These are generic versions of Rifadin — a switch from the brand goes through your pharmacist or prescriber. Some listings are repackagers, which relabel another company’s product. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Other dosage forms of rifampin

A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:

Therapeutic equivalents & pricing 4 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Rifadin IV 600 mg/10mLNDC 00068-0597-01 Sanofi-Aventis 1 vial — AP Discontinued
Rifampin 600 mgNDC 00143-9230-01 Hikma 1 injection — AP FDA listed
Rifampin 600 mgNDC 63323-0351-20 Fresenius 1 vial — AP FDA listed
Rifampin 600 mg/10mLNDC 67457-0445-60 Mylan 1 vial — AP FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Rifadin — that fall in the same broad treatment class (antitubercular antibiotics) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Codes & classification for pharmacists and billers
GCN Seq No 013645
GCN 41470
HICL code 004040
Ingredient (HICL) Rifampin
HIC1 code W
Therapeutic class — broad (HIC1) Anti-Infecting Agents
HIC2 code W1
Therapeutic class — intermediate (HIC2) Antibiotics
HIC3 code W1G
Therapeutic class — specific (HIC3) Antitubercular Antibiotics
AHFS code 08:12.28.30
AHFS class Rifamycin Antibiotics
FDB label name RIFAMPIN IV 600 MG VIAL
FDB brand name Rifampin
Legend status F — Federal legend — prescription drug or device
GPI-1409000080002120
GPI classrifAMPin
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other anti-infective shortages

Rifadin shortage FAQs

Is Rifadin still in shortage?
Yes — as of Oct 8, 2026 the FDA lists Rifadin (and its generic, rifampin injections) as a current shortage (status: “Current”, first reported Feb 17, 2021). Brand-name Rifadin is short too: Sanofi-Aventis U.S. says 1 of its 2 Rifadin products is unavailable and 1 is being discontinued. The FDA’s record for this shortage covers 4 products from 3 companies. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Which strengths of Rifadin are affected?
The FDA record covers 2 strengths: 600 mg, 600 mg/10 mL. We could not find a company still making 600 mg/10 mL right now. Every other strength is still made by at least one company, though stock varies by pharmacy.
Why is Rifadin in shortage?
The companies reporting it blame a company discontinuing its product and rising demand.
Which Rifadin products are affected?
Rifampin Injection, 600 mg (NDC 63323-0351-20); Rifampin Injection, 600 mg (NDC 67457-0445-60); Rifadin Injection, 600 mg (NDC 00068-0597-01) and 1 more. The full per-NDC list (availability, company and status) is in the table above — each NDC links to its own page.
When will Rifadin be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Rifadin or its generic somewhere?
6 other dosage forms of rifampin are also listed. See “Where else can I get Rifadin or its generic?” above — stock still varies by pharmacy.
Is the brand or the generic affected?
The FDA record names Rifadin as well as generic rifampin injections. Brand-name Rifadin is short too: Sanofi-Aventis U.S. says 1 of its 2 Rifadin products is unavailable and 1 is being discontinued. Availability also differs between companies — check the per-NDC table and confirm with your pharmacy.
What should I do if I take Rifadin?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another company or a different strength or package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Rifadin shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (0–2)Several companies still list it and most strengths or pack sizes are still listed by someone — counting both the companies reporting the shortage and the companies listing the same medicine without a report. A listing is not a stock check.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes without a source, or a long-running outage. A company’s discontinuation notice is not an outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (companies listing the same ingredient & form — the "other companies" the rating counts); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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