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Chlorothiazide Oral Suspension shortage

Chlorothiazide Oral Suspension is currently listed in shortage by the FDA. The FDA lists 1 affected product. This page was last refreshed from FDA data on Oct 5, 2026.

To Be Discontinued ⚠ Supply risk: High Cardiovascular 1 product 237 days First posted Feb 10, 2026 Updated Feb 10, 2026
Here’s the bottom line

Xact Nutrition is stopping chlorothiazide oral suspension (250 mg/5 mL), and this change may be permanent. No other manufacturer is currently listed as a source for this medicine.

Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
1
Affected NDCs
1
Reporting manufacturers
0/1
Reporting mfrs supplying
0/1
Affected strengths supplied
237
Days in shortage
7,744
Medicaid Rx (2026)
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Oct 5, 2026 · today

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Chlorothiazide Oral Suspension. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
1 NDCs
To be discontinued 1
Affected strengths still supplied
Among manufacturers reporting this shortage
0/1 strengths
No supply 1
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
0/1 makers
No supply 1
✓ Other manufacturers not reporting a shortage
Still-marketed Chlorothiazide Oral Suspension from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
Plus 1 alternative dosage form of Chlorothiazide.
See all other options & details →
Shortage timeline
  1. Feb 10, 2026
    Currently in shortage
    1 of 1 product affected.
  2. Feb 10, 2026
    First reported to the FDA
    1 product first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Salix Pharmaceuticals, a division of Bausch Health US, LLC 📞 800-321-4576 1 NDC click to expand
Status NDC / product Strength Availability Related information Reason
To Be Discontinued Diuril, Oral Suspension, 250 mg/5mL (NDC 65649-311-12) NDC 65649-0311-12 — — — —

These rows are manufacturer reports to the FDA for Chlorothiazide Oral Suspension — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Chlorothiazide Oral Suspension? options further down this page.

Why is Chlorothiazide Oral Suspension in shortage?

Salix Pharmaceuticals (a division of Bausch Health) has reported to the FDA that they are permanently stopping production of Diuril oral suspension, 250 mg/5 mL. This means this particular liquid form of chlorothiazide from this manufacturer will no longer be made going forward.

Unfortunately, Salix did not share a specific public reason for why they are discontinuing this product — just that it is being discontinued. It's worth knowing that this report only reflects what Salix has filed with the FDA, so it speaks only to their version of this liquid suspension. Other manufacturers may have their own situations reported separately elsewhere on this page.

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Chlorothiazide Oral Suspension, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Chlorothiazide Oral Suspension?

Chlorothiazide oral suspension (also sold as Diuril) is currently on the FDA shortage list. I want to walk you through what this means so you can plan your next steps calmly.

The one strength on this record, 250 mg/5mL, does not have an available source reported right now. This is the strength most people take as the liquid form, so it is likely the one that affects you.

This product is listed as to be discontinued by the manufacturer that filed this report (Salix Pharmaceuticals). That means the supply problem may be permanent rather than a short-term gap, so a conversation with your prescriber is the right next step. No estimated-recovery date is given in the data.

Here is what I suggest:

  • Do not stop, skip, or change your doses on your own — keep taking it as prescribed while you sort out a plan.
  • Because this liquid is being discontinued, talk with your prescriber or pharmacist soon about options, such as a clinician-chosen alternative that fits your needs.
  • Manufacturer contact numbers are listed on this page for reference, though pharmacies usually make these calls.

Please remember this comes from national, manufacturer-reported FDA data and may not match your local pharmacy's actual stock. Your pharmacist and prescriber can guide you to the safest choice for you.

See “Where else can I get Chlorothiazide Oral Suspension?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Chlorothiazide guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Chlorothiazide guide →

Where else can I get Chlorothiazide Oral Suspension?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Chlorothiazide Oral Suspension is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Alternative dosage forms of Chlorothiazide

A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:

Therapeutic equivalents & pricing 1 productclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Diuril 250 mg/5mLNDC 65649-0311-12 Salix 1 bottle $0.277 — FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Chlorothiazide Oral Suspension — that fall in the same broad treatment class (thiazide and related diuretics) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 008172
GCN 34790
HICL code 003646
Ingredient (HICL) Chlorothiazide
HIC1 code R
Therapeutic class — broad (HIC1) Kidney/Urinary Tract
HIC2 code R1
Therapeutic class — intermediate (HIC2) Affect Primarily Kidneys/Urinary Tract
HIC3 code R1F
Therapeutic class — specific (HIC3) Thiazide And Related Diuretics
AHFS code 24:36.20.00
AHFS class Thiazide Diuretics (24:36)
FDB label name DIURIL 250 MG/5 ML ORAL SUSP
FDB brand name Diuril
Legend status F — Federal legend — prescription drug or device
GPI-1437600020001805
GPI classDiuril
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other cardiovascular shortages

Chlorothiazide Oral Suspension shortage FAQs

Is Chlorothiazide Oral Suspension in shortage?
Yes — the FDA currently lists Chlorothiazide Oral Suspension in shortage (status: “To Be Discontinued”, first reported Feb 10, 2026). 1 of 1 product is affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Which products are affected?
Diuril, Oral Suspension, 250 mg/5mL (NDC 65649-311-12) (NDC 65649-0311-12). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Chlorothiazide Oral Suspension be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Chlorothiazide somewhere?
1 alternative dosage form of Chlorothiazide is also listed. See “Where else can I get Chlorothiazide Oral Suspension?” above — stock still varies by pharmacy.
What should I do if I take Chlorothiazide Oral Suspension?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Chlorothiazide Oral Suspension shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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